We are seeking candidates for a Research Assistant position to join the Structural Genomics Consortium. We aim to promote the discovery of new drugs by investigating genes linked to human disease.
The SGC aims to decipher the function of genes involved in human disease using structural, biochemical, and chemical approaches. Our central activity is purification, crystallization and structure determination by X-ray crystallography. The Genome Integrity group (headed by Dr Opher Gileadi) has focussed on genes involved in DNA repair and its regulation, but also on various other genes (often of unknown function) implicated in human diseases.
You will have experience in recombinant protein expression, protein biochemistry, biochemical and cellular assays, or protein crystallization. You will purify a variety of proteins, pursue crystallization projects, will test the quality of the proteins and crystals, perform biophysical characterization (e.g. mass spec, ITC), and perform activity assays. After learning the core techniques, you will be expected to drive the optimization and development of research methods, and to help in tutoring new students and members of staff in your areas of expertise.
You will be educated to degree level or equivalent and possess previous experience in animal cell culture. Familiarity with MS Office products, such as Word, Excel, and PowerPoint would be essential.
The job involves use of sophisticated equipment and extensive electronic documentation.
You will also be required to upload a CV and supporting statement which explains how you meet the selection criteria for the post.
Only applications received before 12.00 noon on 5 April 2017 will be considered.
The SGC as part of the Nuffield Department of Medicine is a family friendly department: http://www.ndm.ox.ac.uk/family-friendly