SGC | Annotated Phylogenetic Trees - Ligand Browser

HDAC1

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APHA KI: 10 µM Pubmed IDs: 20139990	Apicidin KI: 0.00004 µM Pubmed IDs: 20139990	CI-994 KI: 0.05 µM Pubmed IDs: 20139990
Depudecin KI: 5.5 µM Pubmed IDs: 20139990	FK-228 KI: 1.1 µM Pubmed IDs: 20139990	HC-Toxin KI: 0.19 µM Pubmed IDs: 20139990
ITF-2357 KI: 0.39 µM Pubmed IDs: 20139990	LACI-824 KI: 9 µM Pubmed IDs: 20139990	LBH-589 KI: 3.2 µM Pubmed IDs: 20139990
MGCD-0103 KI: 0.009 µM Pubmed IDs: 20139990	MS-275 KI: 0.022 µM Pubmed IDs: 20139990	4-PBHA KI: 0.295 µM Pubmed IDs: 20139990
PXD-101 KI: 0.25 µM Pubmed IDs: 20139990	Pyroxamide KI: 0.0027 µM Pubmed IDs: 20139990	SAHA KI: 0.0013 µM Pubmed IDs: 20139990
Scriptaid KI: 8 µM Pubmed IDs: 20139990	SuberoHA KI: 0.019 µM Pubmed IDs: 20139990	Trichostatin KI: 0.8 µM Pubmed IDs: 20139990
Tubacin KI: 0.028 µM Pubmed IDs: 20139990

HDAC2

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APHA KI: 0.125 µM Pubmed IDs: 20139990	Apicidin KI: 0.00012 µM Pubmed IDs: 20139990	CI-994 KI: 0.19 µM Pubmed IDs: 20139990
Depudecin KI: 12.5 µM Pubmed IDs: 20139990	FK-228 KI: 0.000038 µM Pubmed IDs: 20139990	HC-Toxin KI: 0.47 µM Pubmed IDs: 20139990
ITF-2357 KI: 0.003 µM Pubmed IDs: 20139990	LACI-824 KI: 0.0014 µM Pubmed IDs: 20139990	LBH-589 KI: 0.00065 µM Pubmed IDs: 20139990
MGCD-0103 KI: 0.034 µM Pubmed IDs: 20139990	MS-275 KI: 0.065 µM Pubmed IDs: 20139990	4-PBHA KI: 0.43 µM Pubmed IDs: 20139990
PXD-101 KI: 0.00085 µM Pubmed IDs: 20139990	Pyroxamide KI: 0.0036 µM Pubmed IDs: 20139990	SAHA KI: 0.0016 µM Pubmed IDs: 20139990
Scriptaid KI: 0.0022 µM Pubmed IDs: 20139990	SuberoHA KI: 0.029 µM Pubmed IDs: 20139990	Trichostatin KI: 0.00065 µM Pubmed IDs: 20139990
Tubacin KI: 0.042 µM Pubmed IDs: 20139990

HDAC3

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APHA KI: 0.25 µM Pubmed IDs: 20139990	Apicidin KI: 0.00026 µM Pubmed IDs: 20139990	CI-994 KI: 0.55 µM Pubmed IDs: 20139990
Depudecin KI: 14.5 µM Pubmed IDs: 20139990	FK-228 KI: 0.00015 µM Pubmed IDs: 20139990	HC-Toxin KI: 1.35 µM Pubmed IDs: 20139990
ITF-2357 KI: 0.003 µM Pubmed IDs: 20139990	LACI-824 KI: 0.0042 µM Pubmed IDs: 20139990	LBH-589 KI: 0.0011 µM Pubmed IDs: 20139990
MGCD-0103 KI: 0.265 µM Pubmed IDs: 20139990	MS-275 KI: 0.36 µM Pubmed IDs: 20139990	4-PBHA KI: 1.65 µM Pubmed IDs: 20139990
PXD-101 KI: 0.0015 µM Pubmed IDs: 20139990	Pyroxamide KI: 0.008 µM Pubmed IDs: 20139990	SAHA KI: 0.005 µM Pubmed IDs: 20139990
Scriptaid KI: 0.0041 µM Pubmed IDs: 20139990	SuberoHA KI: 0.125 µM Pubmed IDs: 20139990	Trichostatin KI: 0.0005 µM Pubmed IDs: 20139990
Tubacin KI: 0.275 µM Pubmed IDs: 20139990

HDAC4

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APHA KI: 17.5 µM Pubmed IDs: 20139990	FK-228 KI: 0.0205 µM Pubmed IDs: 20139990	ITF-2357 KI: 1.05 µM Pubmed IDs: 20139990
LACI-824 KI: 2.25 µM Pubmed IDs: 20139990	LBH-589 KI: 0.55 µM Pubmed IDs: 20139990	PXD-101 KI: 0.38 µM Pubmed IDs: 20139990
Scriptaid KI: 7.5 µM Pubmed IDs: 20139990	Trichostatin KI: 1.4 µM Pubmed IDs: 20139990	Tubacin KI: 17 µM Pubmed IDs: 20139990
lobera13_1 IC50: 0.126 µM Pubmed IDs: 23524983	burli13_cmpd31 IC50: 0.025 µM Pubmed IDs: 24261862

HDAC5

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APHA KI: 11.5 µM Pubmed IDs: 20139990	FK-228 KI: 0.55 µM Pubmed IDs: 20139990	ITF-2357 KI: 0.6 µM Pubmed IDs: 20139990
LACI-824 KI: 0.42 µM Pubmed IDs: 20139990	LBH-589 KI: 0.08 µM Pubmed IDs: 20139990	4-PBHA KI: 16 µM Pubmed IDs: 20139990
PXD-101 KI: 0.175 µM Pubmed IDs: 20139990	Pyroxamide KI: 4.75 µM Pubmed IDs: 20139990	SAHA KI: 3.6 µM Pubmed IDs: 20139990
Scriptaid KI: 1 µM Pubmed IDs: 20139990	SuberoHA KI: 9.5 µM Pubmed IDs: 20139990	Trichostatin KI: 0.26 µM Pubmed IDs: 20139990
Tubacin KI: 1.5 µM Pubmed IDs: 20139990	lobera13_1 IC50: 0.08 µM Pubmed IDs: 23524983

HDAC6

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APHA KI: 0.03 µM Pubmed IDs: 20139990	FK-228 KI: 0.0095 µM Pubmed IDs: 20139990	ITF-2357 KI: 0.0042 µM Pubmed IDs: 20139990
LACI-824 KI: 0.0095 µM Pubmed IDs: 20139990	LBH-589 KI: 0.0015 µM Pubmed IDs: 20139990	Niltubacin KI: 2.2 µM Pubmed IDs: 20139990
4-PBHA KI: 0.15 µM Pubmed IDs: 20139990	PXD-101 KI: 0.0016 µM Pubmed IDs: 20139990	Pyroxamide KI: 0.0048 µM Pubmed IDs: 20139990
SAHA KI: 0.0016 µM Pubmed IDs: 20139990	Scriptaid KI: 0.00025 µM Pubmed IDs: 20139990	SuberoHA KI: 0.0145 µM Pubmed IDs: 20139990
Trichostatin KI: 0.001 µM Pubmed IDs: 20139990	Tubacin KI: 0.016 µM Pubmed IDs: 20139990	blackburn13_cmpd5a IC50: 0.036 µM Pubmed IDs: 23964961

HDAC7

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APHA KI: 7 µM Pubmed IDs: 20139990	FK-228 KI: 1.25 µM Pubmed IDs: 20139990	ITF-2357 KI: 0.24 µM Pubmed IDs: 20139990
LACI-824 KI: 9.5 µM Pubmed IDs: 20139990	LBH-589 KI: 4.55 µM Pubmed IDs: 20139990	PXD-101 KI: 0.075 µM Pubmed IDs: 20139990
Scriptaid KI: 2.25 µM Pubmed IDs: 20139990	Trichostatin KI: 0.195 µM Pubmed IDs: 20139990	Tubacin KI: 8.5 µM Pubmed IDs: 20139990
lobera13_1 IC50: 0.036 µM Pubmed IDs: 23524983

HDAC8

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APHA KI: 0.6 µM Pubmed IDs: 20139990	Apicidin KI: 0.049 µM Pubmed IDs: 20139990	FK-228 KI: 0.00015 µM Pubmed IDs: 20139990
HC-Toxin KI: 10.5 µM Pubmed IDs: 20139990	ITF-2357 KI: 0.039 µM Pubmed IDs: 20139990	LACI-824 KI: 0.34 µM Pubmed IDs: 20139990
LBH-589 KI: 0.105 µM Pubmed IDs: 20139990	Niltubacin KI: 0.75 µM Pubmed IDs: 20139990	4-PBHA KI: 1.85 µM Pubmed IDs: 20139990
PXD-101 KI: 0.025 µM Pubmed IDs: 20139990	Pyroxamide KI: 1 µM Pubmed IDs: 20139990	SAHA KI: 0.48 µM Pubmed IDs: 20139990
Scriptaid KI: 0.105 µM Pubmed IDs: 20139990	SuberoHA KI: 0.95 µM Pubmed IDs: 20139990	Trichostatin KI: 0.045 µM Pubmed IDs: 20139990
Tubacin KI: 0.17 µM Pubmed IDs: 20139990

HDAC9

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lobera13_1
IC50: 0.019 µM
Pubmed IDs: 23524983

SIRT1

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EX-527 IC50: 0.1 µM Pubmed IDs: 16354677	trapp_cmpd_12J IC50: 3.5 µM Pubmed IDs: 17149860	suramin_analog IC50: 0.093 µM Pubmed IDs: 17628866
dish13_cmpd31 IC50: 0.004 µM Pubmed IDs: 23570514

SIRT2

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medda_cmpd_6j IC50: 1 µM Pubmed IDs: 19419202	trapp_cmpd_12J IC50: 0.8 µM Pubmed IDs: 17149860	dish13_cmpd31 IC50: 0.001 µM Pubmed IDs: 23570514
SirReal2 IC50: 0.4 µM Pubmed IDs: 25672491	TM IC50: 0.028 µM Pubmed IDs: 26977881

SIRT3

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dish13_cmpd31
IC50: 0.007 µM
Pubmed IDs: 23570514