SGC | Annotated Phylogenetic Trees - Ligand Browser

PARP1

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BMN673 IC50: 0.0006 µM Pubmed IDs: 23881923	Niraparib IC50: 0.002 µM Pubmed IDs: 23881923	Olaparib IC50: 0.004 µM Pubmed IDs: 18800822
PJ34 IC50: 0.02 µM Pubmed IDs: 22343925,12006805,18809672	Rucaparib IC50: 0.0014 µM Pubmed IDs: 17363489	Veliparib IC50: 0.005 µM Pubmed IDs: 23881923,24398383,19759537
DR2313 IC50: 0.2 µM Pubmed IDs: 15466246	ME328 IC50: 6.3 µM Pubmed IDs: 23742272	5-AIQ IC50: 0.94 µM Pubmed IDs: 21127791
DPQ IC50: 4.5 µM Pubmed IDs: 18409175

PARP10

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Olaparib
IC50: 2.04 µM
Pubmed IDs: 23485441

PARP15

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Olaparib
IC50: 0.925 µM
Pubmed IDs: 23485441

PARP2

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Niraparib IC50: 0.002 µM Pubmed IDs: 24398383	Olaparib IC50: 0.001 µM Pubmed IDs: 18800822	PJ34 IC50: 0.02 µM Pubmed IDs: 22343925
XAV939 IC50: 0.114 µM Pubmed IDs: 19759537	ME328 IC50: 10.2 µM Pubmed IDs: 23742272	5-AIQ IC50: 1.04 µM Pubmed IDs: 21127791
DPQ IC50: 5.3 µM Pubmed IDs: 18409175

PARP3

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Niraparib
IC50: 0.33 µM
Pubmed IDs: 24398383

ME328
IC50: 0.8 µM
Pubmed IDs: 23742272

PARP4

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Niraparib
IC50: 1.3 µM
Pubmed IDs: 19873981

TNKS1

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Niraparib IC50: 0.57 µM Pubmed IDs: 24398383	Olaparib IC50: 1.5 µM Pubmed IDs: 18800822	PJ34 IC50: 0.57 µM Pubmed IDs: 19759537
Rucaparib IC50: 0.014 µM Pubmed IDs: 24900770	XAV939 IC50: 0.011 µM Pubmed IDs: 19759537	ME328 IC50: 30 µM Pubmed IDs: 23742272

TNKS2

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PJ34
IC50: 0.22 µM
Pubmed IDs: 24900770

XAV939
IC50: 0.004 µM
Pubmed IDs: 19759537

ME328
IC50: 30 µM
Pubmed IDs: 23742272