SGC Oxford seeks to solve the structures of human proteins of medical relevance and place them into the public domain without restriction. Using these structures and the reagents generated as part of the structure determination process as well as the chemical probes identified, we work with organisations within Oxford, the UK and the rest of the world to further the understanding of the biological roles of these proteins. We have particular interests in human protein kinases, metabolism-associated proteins, integral membrane proteins and proteins associated with epigenetics.
The SGC Oxford laboratories, under the direction of Prof. Chas Bountra, are housed within the University's Old Road Campus located up the hill in Headington, Oxford. SGC Oxford is part of the Nuffield Department of Clinical Medicine and scientists at SGC Oxford are affiliated with several University Departments including the Botnar Research Centre at The Institute of Musculoskeletal Sciences and the Department of Oncology.