SGC Publications

 

Müller S, Filippakopoulos P, Knapp S. (2011)

Bromodomains as therapeutic targets

ERMM in press

 

Picaud, SS, Kavanagh, KL, Yue, W W, Lee, WH, Müller-Knapp S, Gileadi, O, Sacchettini, J Oppermann, U. (2011).

Structural basis of fumarate hydratase deficiency.

J Inherited Metabol. Disease. 34(3), 671-676

 

Müller S and Knapp S. (2010).

Targeting kinases for the treatment of inflammatory disease.

Expert Opinion in Drug Discovery 5, 867-881.

 

Müller S, Weigelt, J. (2010)

Open-access public-private partnerships to enable drug discovery--new approaches.

iDrugs 13(3),175-80

 

Fedorov, O, Müller S, Knapp S. (2010)

The (un)targeted cancer kinome.

Nat. Chem. Biol. 6(3),166-169.

 

Filippakopoulos P, Müller S, Knapp S. (2009)

SH2 domains: modulators of nonreceptor tyrosine kinase activity.

Curr Opin Struct Biol. 19(6),643-9.

 

Müller S, Knapp S. (2009)

Out of the box binding determines specificity of SH2 domain interaction.

Structure. 17(8),1040-1.

 

Barr, AJ Ugochukwu, E, Lee, WH, King, O, Filippakopoulos, P, Müller S, Knapp, S. (2009).

Large-scale structural analysis of the classical human protein tyrosine phosphatome.

Cell.136(2), 352-63.

 

Gileadi O, Knapp S, Lee WH, Marsden BD, Müller S, Niesen FH, Kavanagh KL, Ball LJ, von Delft F, Doyle DA, Oppermann UC, Sundström M. (2007).

The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins.

J Struct Funct Genomics. 8(2-3), 107-19.

 

Bunkoczi G, Salah E, Filippakopoulos P, Fedorov O, Müller S, Sobott F, Parker SA, Zhang H, Min W, Turk BE, Knapp S. (2007).

Structural and functional characterization of the human protein kinase ASK1.

Structure. 15(10), 1215-26.

 

Fedorov O, Marsden B, Pogacic V, Rellos P, Müller S, Bullock AN, Schwaller J, Sundström M, Knapp S. (2007)

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.

Proc Natl Acad Sci U S A. 104(51), 20523-8.

 

 

 

Pre-SGC Publications

 

Sitia G, Iannacone M, Müller S, Bianchi ME, Guidotti LG. (2007).

Treatment with HMGB1 inhibitors diminishes CTL-induced liver disease in HBV transgenic mice.

J Leukoc Biol. 81,100-7.

 

Limana F, Germani A, Zacheo A, Kajstura J, Di Carlo A, Borsellino G, Leoni O, Palumbo R, Battistini L, Rastaldo R, Müller S, Pompilio G, Anversa P, Bianchi ME, Capogrossi MC. (2005).

Exogenous high-mobility group box 1 protein induces myocardial regeneration after infarction via enhanced cardiac C-kit+ cell proliferation and differentiation.

Circ Res. 97, 73-83.

 

Knapp, S, Müller, S, Digilio, G, Comelli, L, Bonaldi, T, Bianchi, ME, Musco, G. (2004).

The long acidic tail of high mobility group box 1 (HMGB1) protein forms an extended and flexible structure that interacts with specific residues within and between the HMG boxes.

Biochemistry 43, 11992-11997

 

Rovere-Querini, P, Capobianco, A, Scaffidi, P, Valentinis, B, Catalanotti, F, Giazzon, M, Dumitriu, IE, Müller, S, Iannacone, M, Traversari, C, Bianchi, ME, Manfredi, AA. (2004)

HMGB1 is an endogenous immune adjuvant released by necrotic cells.

EMBO Rep. 8, 825-830.

 

Müller, S, Ronfani, L, Bianchi ME. (2004)

Regulated expression and subcellular localization of HMGB1, a chromatin protein with a cytokine function.

J. Int. Med. 255, 332-343

 

Agresti, A, Lupo, R, Bianchi, ME, Müller, S. (2003)

HMGB1 interacts differentially with members of the Rel family of transcription factors.

Biochem Biophys Res Commun, 302(2), 421-426.

 

Müller, S, Bianchi, ME, Knapp S. (2001).

Thermodynamics of HMGB1 interaction with duplex DNA.

Biochemistry 34,1 0254-61

 

Müller, S, Scaffidi, P, Degryse, B, Bonaldi, T, Ronfani, L, Agresti, A, Beltrame, M, Bianchi ME. (2001).

The double life of HMGB1 chromatin protein: architectural factor and extracellular signal.

EMBO J. 20, 4337-4340.

 

Degryse, B, Bonaldi, T, Scaffidi, P, Müller, S, Resnati, M, Arrigoni, G, Bianchi, ME. (2001).

The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells.

J Cell Biol. 152, 1197-206.

 

Chauveau, C, Jansson, E, Müller, S, Cogne, M, Pettersson, S. (1999).

Cutting edge: Ig heavy chain 3' HS1-4 directs correct spatial position-independent expression of a linked transgene to B lineage cells.

J. Immunol. 163, 4637-4641

 

Müller, S, Maas, A, Islam, CT, Sideras, P, Suske, G, Philipsen, S, Xanthopoulos, KG, Hendricks, RW, Smith, CIE. (1999).

Synergistic activation of the human Btk promoter by transcription factors Sp1/3 and PU.1.

Biochem. Biophys. Res. Comm. 259, 364-369

 

Smith, CIE, Bäckesjö, M, Berglöf, A, Brandén, L, Islam, T, Mattsom, PT, Mohamed, AJ, Müller, S, Nore, B, Vihinen, M (1998).

X-linked agammaglobulinemia: lack of mature B lineage cells caused by mutations in the Btk kinase.

Springer Seminars in Immunopathology 19, 369-381

 

Müller, S, Sideras, P, Smith, CIE Xanthopoulos, KG. (1996).

Cell specific expression of human Bruton's agammaglobulinemia tyrosine kinase gene (Btk) is regulated by Sp1- and Spi-1/PU.1-family members.

Oncogene 13, 1955-1964.

 

Khan, WN, Alt, FW, Gerstein, RM, Malynn, BA, Larsson, I, Rathbun, G, Davidson, L, Müller, S, Kantor, AB, Herzenberg, LA, Rosen, FS, Sideras, P. (1995).

Defective B cell development and function in Btk-deficient mice.

Immunity 3, 283-299.

 

Vorechovski, I, Vihinen, M, de Saint Basile, G, Honsova, S, Hammarström, L, Müller, S, Nilsson, L, Fischer, A, Smith, CIE. (1995).

DNA-based mutation analysis of Bruton's tyrosine kinase gene in patients with X-linked agammaglobulinaemia.

Hum. Mol. Gen. 4, 51-58.

 

Sideras, P* and Müller, S,* Shiels, H, Jin, H, Khan, WN, Nilsson, L, Parkinson, E, Thomas, JD, Branden, L, Larsson, I, Paul, WE, Rosen, FS, Alt, JD, Vetrie, D, Smith, CIE, Xanthopoulos, KG. (1994).

Genomic organization of mouse and human Bruton's agammaglobulinemia tyrosine kinase (Btk) loci.

J.Immunol. 153, 5607-5617.

* shared first authorship

 

Hagen, G, Müller, S, Beato, M,  Suske G. (1994).

Sp1-mediated transcriptional activation is repressed by Sp3.

EMBO J. 13, 3843-3851

 

Hagen, G., Müller, S., Beato, M. and Suske, G. (1992).

Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes.

Nucleic Acids Res. 20, 5519-5525.