Search Pubmed for publications of Dr. Park.
Reference List:
Strushkevich N, Usanov SA, Plotnikov AN, Jones G, Park HW: Structural analysis of CYP2R1 in complex with vitamin D3. J.Mol.Biol. 2008, 380:95-106.
Senisterra GA, Soo HB, Park HW, Vedadi M: Application of high-throughput isothermal denaturation to assess protein stability and screen for ligands. J.Biomol.Screen. 2008, 13:337-342.
Tempel W, Tong Y, Dimov S, Bochkarev A, Park H: First crystallographic models of human TBC domains in the context of a family-wide structural analysis. Proteins 2008, 71:497-502.
Park HW: Structure determination of the motor domain of yeast kinesin kar3 by x-ray crystallography. Methods Mol.Biol. 2007, 392:199-211.
Tong Y, Chugha P, Hota PK, Alviani RS, Li M, Tempel W, Shen L, Park HW, Buck M: Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain. J.Biol.Chem. 2007, 282:37215-37224.
Tempel W, Rabeh WM, Bogan KL, Belenky P, Wojcik M, Seidle HF, Nedyalkova L, Yang T, Sauve AA, Park HW, Brenner C: Nicotinamide riboside kinase structures reveal new pathways to NAD+. PLoS.Biol. 2007, 5:e263.
Hong BS, Senisterra G, Rabeh WM, Vedadi M, Leonardi R, Zhang YM, Rock CO, Jackowski S, Park HW: Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder. J.Biol.Chem. 2007, 282:27984-27993.
Shanmuganatham KK, Ravichandran M, Howe MM, Park HW: Crystallization and preliminary X-ray analysis of phage Mu activator protein C in a complex with promoter DNA. Acta Crystallogr.Sect.F.Struct.Biol.Cryst.Commun. 2007, 63:620-623.
Hong BS, Yun MK, Zhang YM, Chohnan S, Rock CO, White SW, Jackowski S, Park HW, Leonardi R: Prokaryotic type II and type III pantothenate kinases: The same monomer fold creates dimers with distinct catalytic properties. Structure. 2006, 14: 1251-1261.
Virga KG, Zhang YM, Leonardi R, Ivey RA, Hevener K, Park HW, Jackowski S, Rock CO, Lee RE: Structure-activity relationships and enzyme inhibition of pantothenamide-type pantothenate kinase inhibitors. Bioorg.Med.Chem. 2006, 14:1007-1020.
Chu HM, Yun M, Anderson DE, Sage H, Park HW, Endow SA: Kar3 interaction with Cik1 alters motor structure and function. EMBO J. 2005, 24:3214-3223.
Ismail SA, Park HW: Structural analysis of human liver glyceraldehyde-3-phosphate dehydrogenase. Acta Crystallogr.D.Biol.Crystallogr. 2005, 61:1508-1513.
Aziz RK, Ismail SA, Park HW, Kotb M: Post-proteomic identification of a novel phage-encoded streptodornase, Sda1, in invasive M1T1 Streptococcus pyogenes. Mol.Microbiol. 2004, 54:184-197.
Brown VM, Krynetski EY, Krynetskaia NF, Grieger D, Mukatira ST, Murti KG, Slaughter CA, Park HW, Evans WE: A novel CRM1-mediated nuclear export signal governs nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase following genotoxic stress. J.Biol.Chem. 2004, 279:5984-5992.
Higuchi H, Bronner CE, Park HW, Endow SA: Rapid double 8-nm steps by a kinesin mutant. EMBO J. 2004, 23:2993-2999.
Ivey RA, Zhang YM, Virga KG, Hevener K, Lee RE, Rock CO, Jackowski S, Park HW: The structure of the pantothenate kinase.ADP.pantothenate ternary complex reveals the relationship between the binding sites for substrate, allosteric regulator, and antimetabolites. J.Biol.Chem. 2004, 279:35622-35629.
Kumaraswami M, Howe MM, Park HW: Crystal structure of the Mor protein of bacteriophage Mu, a member of the Mor/C family of transcription activators. J.Biol.Chem. 2004, 279:16581-16590.
Rock CO, Park HW, Jackowski S: Role of feedback regulation of pantothenate kinase (CoaA) in control of coenzyme A levels in Escherichia coli. J.Bacteriol. 2003, 185:3410-3415.
Yun M, Bronner CE, Park CG, Cha SS, Park HW, Endow SA: Rotation of the stalk/neck and one head in a new crystal structure of the kinesin motor protein, Ncd. EMBO J. 2003, 22:5382-5389.
Yun M, Keshvara L, Park CG, Zhang YM, Dickerson JB, Zheng J, Rock CO, Curran T, Park HW: Crystal structures of the Dab homology domains of mouse disabled 1 and 2. J.Biol.Chem. 2003, 278:36572-36581.
Kwak BY, Zhang YM, Yun M, Heath RJ, Rock CO, Jackowski S, Park HW: Structure and mechanism of CTP:phosphocholine cytidylyltransferase (LicC) from Streptococcus pneumoniae. J.Biol.Chem. 2002, 277:4343-4350.
Rock CO, Heath RJ, Park HW, Jackowski S: The licC gene of Streptococcus pneumoniae encodes a CTP:phosphocholine cytidylyltransferase. J.Bacteriol. 2001, 183:4927-4931.
Yun M, Zhang X, Park CG, Park HW, Endow SA: A structural pathway for activation of the kinesin motor ATPase. EMBO J. 2001, 20:2611-2618.
Rodriguez AC, Park HW, Mao C, Beese LS: Crystal structure of a pol alpha family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. 9 degrees N-7. J.Mol.Biol. 2000, 299:447-462.
Yun M, Park CG, Kim JY, Rock CO, Jackowski S, Park HW: Structural basis for the feedback regulation of Escherichia coli pantothenate kinase by coenzyme A. J.Biol.Chem. 2000, 275:28093-28099.
Yun M, Park CG, Kim JY, Park HW: Structural analysis of glyceraldehyde 3-phosphate dehydrogenase from Escherichia coli: direct evidence of substrate binding and cofactor-induced conformational changes. Biochemistry 2000, 39:10702-10710.
Park HW, Beese LS: Protein farnesyltransferase. Curr.Opin.Struct.Biol. 1997, 7: 873-880.
Park HW, Boduluri SR, Moomaw JF, Casey PJ, Beese LS: Crystal structure of protein farnesyltransferase at 2.25 angstrom resolution. Science 1997, 275:1800-1804.
Park HW, Kim ST, Sancar A, Deisenhofer J: Crystal structure of DNA photolyase from Escherichia coli. Science 1995, 268:1866-1872.
Park HW, Sancar A, Deisenhofer J: Crystallization and preliminary crystallographic analysis of Escherichia coli DNA photolyase. J.Mol.Biol. 1993, 231:1122-1125.
