SGC | STRUCTURES GALLERY

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1128 structures

Name: Human vaccinia related kinase 1
PDB Code: 3OP5
Target Class: Protein Kinase
Target: VRK1
Disease Area:
Date Deposited: Aug 31 2010

Name: Human Cbl-c (Cbl-3) TKB domain in complex with EGFR pY1069 peptide
PDB Code: 3OP0
Target Class: Signalling proteins
Target: Cbl-c + EGFR pY1069 peptide
Disease Area:
Date Deposited: Aug 31 2010

Name: Human transketolase
PDB Code: 3OOY
Target Class: Transferases
Target: TKT
Disease Area: cancer, metabolism, signalling, neurobiology
Date Deposited: Aug 31 2010

Name: Human activin A receptor, type I in complex with the imidazo[1,2-b]pyridazine inhibitor K00507
PDB Code: 3OOM
Target Class: Protein Kinase
Target: ACVR1 + K00507
Disease Area: cancer, signalling
Date Deposited: Aug 31 2010

Name: Human bromodomain containing protein 2 in complex with SGCBD01 probe against BET subfamily
PDB Code: 3ONI
Target Class: Bromodomain
Target: BRD2 + SGCBD01 Probe
Disease Area: cancer
Date Deposited: Aug 31 2010

Name: Trypanosoma brucei HSP90 (Tb10.26.1080) N-terminal domain, in complex with a thienopyrimidine derivative
PDB Code: 3OMU
Target Class: Miscellaneous
Target: HSP90
Disease Area: parasitic disease
Date Deposited: Aug 27 2010

Name: Human E3 ligase UHRF2, SRA domain
PDB Code: 3OLN
Target Class: Ubiquitylation
Target: UHRF2
Disease Area: cancer, chromatin and epigenetics, signalling
Date Deposited: Aug 26 2010

Name: Human staphylococcal nuclease and tudor domain containing 1, extended Tudor domain, in complex with PIWIL1 peptide R4me2s
PDB Code: 3OMC
Target Class: Methyl-lysine readers
Target: SND1
Disease Area: chromatin and epigenetics
Date Deposited: Aug 26 2010

Name: Human staphylococcal nuclease and tudor domain containing 1, extended Tudor domain, in complex with PIWIL1 peptide R14me2s
PDB Code: 3OMG
Target Class: Methyl-lysine readers
Target: SND1
Disease Area: chromatin and epigenetics
Date Deposited: Aug 26 2010

Name: Human OTU domain containing 7A, UBA-like domain
PDB Code: 2L2D
Target Class: Ubiquitylation
Target: OTUD7A
Disease Area: signalling
Date Deposited: Aug 17 2010

Name: Human Ras homolog enriched in brain like 1, in complex with GMP-PNP
PDB Code: 3OES
Target Class: GTPases
Target: RHEBL1
Disease Area: signalling
Date Deposited: Aug 13 2010

Name: Human kelch-like protein 2 (Mayven)
PDB Code: 2XN4
Target Class: Miscellaneous
Target: KLHL2
Disease Area:
Date Deposited: Jul 30 2010

Name: Human PHD finger protein 13, PHD-type zinc finger domain, in complex with H3K4me3
PDB Code: 3O7A
Target Class: Methyl-lysine readers
Target: PHF13
Disease Area: chromatin and epigenetics
Date Deposited: Jul 30 2010

Name: Trypanosoma brucei HSP90 (Tb10.26.1080) N-terminal domain, in complex with inhibitor BIIB021
PDB Code: 3O6O
Target Class: Miscellaneous
Target: HSP90
Disease Area: parasitic disease
Date Deposited: Jul 29 2010

Name: Human PHD finger protein 13, PHD-type zinc finger domain
PDB Code: 3O70
Target Class: Methyl-lysine readers
Target: PHF13
Disease Area: chromatin and epigenetics
Date Deposited: Jul 29 2010

Name: Human JMJD2C catalytic domain
PDB Code: 2XML
Target Class: Oxidoreductases
Target: JMJD2C
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Jul 28 2010

Name: Human Dehydrogenase/Reductase (SDR family) member 4 (DHRS4)
PDB Code: 3O4R
Target Class: Oxidoreductases
Target: DHRS4
Disease Area:
Date Deposited: Jul 27 2010

Name: Plasmodium vivax CDPK3 (PVX_119610), CAD domain
PDB Code: 3O4Y
Target Class: Protein Kinase
Target: PvCDPK3
Disease Area: parasitic disease
Date Deposited: Jul 27 2010

Name: Human membrane protein, palmitoylated 7, PDZ domain
PDB Code: 3O46
Target Class: Non-protein Kinase
Target: MPP7
Disease Area: cancer, signalling
Date Deposited: Jul 26 2010

Name: Human ADP-ribosylation factor GTPase activating protein 1 - ARF1 fusion protein in complex with GDP
PDB Code: 3O47
Target Class: G-Protein Regulators
Target: ARFGAP1
Disease Area: cancer, neurobiology
Date Deposited: Jul 26 2010

Name: Human phosphoglycerate mutase family member 5 (PGAM5) in complex with phosphate
PDB Code: 3O0T
Target Class: Phosphatases
Target: PGAM5
Disease Area: signalling
Date Deposited: Jul 20 2010

Name: Human CECR2 (Bromodomain)
PDB Code: 3NXB
Target Class: Bromodomain
Target: CECR2
Disease Area:
Date Deposited: Jul 13 2010

Name: Human ABL2 in complex with Aurora Kinase Inhibitor VX-680
PDB Code: 3NSV
Target Class: Protein Kinase
Target: ABL2 + VX-680
Disease Area: cancer, signalling, neurobiology
Date Deposited: Jul 02 2010

Name: Human ephrin type-A receptor 7, ligand binding domain
PDB Code: 3NRU
Target Class: Protein Kinase
Target: EPHA7
Disease Area: cancer, signalling
Date Deposited: Jun 30 2010

Name: Crystal structure of human SHIP-2
PDB Code: 3NR8
Target Class: Phosphoinosotide dependent signalling
Target: SHIP2
Disease Area: metabolism, signalling
Date Deposited: Jun 30 2010

Name: Human YSK1A (Yeast Sps1/Ste20-related Kinase 1)
PDB Code: 2XIK
Target Class: Protein Kinase
Target: YSK1
Disease Area: signalling
Date Deposited: Jun 30 2010

Name: Human TatD DNase domain containing 1
PDB Code: 2XIO
Target Class: Miscellaneous
Target: TATDN1
Disease Area:
Date Deposited: Jun 30 2010

Name: Human Peripheral myelin protein 2
PDB Code: 3NR3
Target Class: Miscellaneous
Target: PMP2
Disease Area: metabolism
Date Deposited: Jun 30 2010

Name: Human methylmalonyl-CoA mutase in binary complex with adenosylcobalamin
PDB Code: 2XIJ
Target Class: Miscellaneous
Target: MUT + adenosylcobalamin
Disease Area: metabolism, cancer, neurobiology
Date Deposited: Jun 30 2010

Name: Human methylmalonyl-CoA mutase in ternary complex with adenosylcobalamin and malonyl CoA
PDB Code: 2XIQ
Target Class: Miscellaneous
Target: MUT + adenosylcobalamin + malonyl CoA
Disease Area: metabolism, cancer, neurobiology
Date Deposited: Jun 30 2010

Name: Human tumor protein p73
PDB Code: 2XIP
Target Class: Miscellaneous
Target: TP73
Disease Area: cancer, signalling, neurobiology
Date Deposited: Jun 30 2010

Name: Human CLK2 (cdc2-like kinase 2)
PDB Code: 3NR9
Target Class: Protein Kinase
Target: CLK2
Disease Area:
Date Deposited: Jun 30 2010

Name: Human EHMT2/G9a, methyltransferase domain, in complex with UNC0638
PDB Code: 3NNI
Target Class: Transferases
Target: EHMT2
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Jun 23 2010

Name: Plasmodium falciparum putative activator of Hsp90 ATPase homolog 1-like protein (PFC0360w)
PDB Code: 3NI8
Target Class: Miscellaneous
Target: Aha-1
Disease Area: parasitic disease
Date Deposited: Jun 15 2010

Name: Plasmodium falciparum mitogen-activated protein kinase 2, PF11_0147
PDB Code: 3NIE
Target Class: Protein Kinase
Target: MAPK2
Disease Area: parasitic disease
Date Deposited: Jun 15 2010

Name: Human membrane protein, palmitoylated 1, 55kDa - Kinase domain
PDB Code: 3NEY
Target Class: Non-protein Kinase
Target: MPP1
Disease Area: signalling
Date Deposited: Jun 09 2010

Name: Human kinesin light chain 1, tetratricopeptide repeat domain
PDB Code: 3NF1
Target Class: Miscellaneous
Target: KLC1
Disease Area: cancer, neurobiology
Date Deposited: Jun 09 2010

Name: Crystal Structure of INPP5B (apo)
PDB Code: 3N9V
Target Class: Phosphoinosotide dependent signalling
Target: INPP5B
Disease Area: signalling
Date Deposited: May 31 2010

Name: Crystal Structure of the Complex between the 25 kDa Subunit and the 59 kDa Subunit (RRM domain) of Human Cleavage Factor Im
PDB Code: 3N9U
Target Class: Nucleotide metabolism
Target: CPSF5_CPSF7
Disease Area: cancer
Date Deposited: May 31 2010

Name: Human mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), in complex with ATP
PDB Code: 3NA3
Target Class: ATPases
Target: MLH1
Disease Area: cancer
Date Deposited: May 31 2010

Name: Human cytochrome P450, family 11, subfamily A, polypeptide 1, in complex with cholesterol
PDB Code: 3N9Y
Target Class: Miscellaneous
Target: CYP11A1
Disease Area: metabolism, drug metabolism and toxicology
Date Deposited: May 31 2010

Name: Human cytochrome P450, family 11, subfamily A, polypeptide 1, in complex with 22-hydroxycholesterol
PDB Code: 3N9Z
Target Class: Miscellaneous
Target: CYP11A1
Disease Area: metabolism, drug metabolism and toxicology
Date Deposited: May 31 2010

Name: Human cytochrome P450, family 11, subfamily A, polypeptide 1, in complex with 20,22-dihydroxycholesterol
PDB Code: 3NA0
Target Class: Miscellaneous
Target: CYP11A1
Disease Area: metabolism, drug metabolism and toxicology
Date Deposited: May 31 2010

Name: Plasmodium berghei mitogen-activated protein kinase, PB000659.00.0
PDB Code: 3N9X
Target Class: Protein Kinase
Target: MAPK
Disease Area: parasitic disease
Date Deposited: May 30 2010

Name: Substrate binding domain of the human heat shock 70kDa protein 9 (mortalin)
PDB Code: 3N8E
Target Class: ATPases
Target: HSPA9
Disease Area: cancer
Date Deposited: May 28 2010

Name: Plasmodium falciparum putative activator of Hsp90 ATPase (PFC0270w)
PDB Code: 3N72
Target Class: Miscellaneous
Target: Aha-1
Disease Area: parasitic disease
Date Deposited: May 26 2010

Name: Human ubiquitin specific protease 8, catalytic domain, in complex with the ubiquitin variant UBV8.2
PDB Code: 3N3K
Target Class: Ubiquitylation
Target: USP8
Disease Area: signalling
Date Deposited: May 20 2010

Name: Human dipeptidyl peptidase 7 in complex with inhibitor GSK237826A
PDB Code: 3N0T
Target Class: Proteases
Target: DPP7
Disease Area:
Date Deposited: May 14 2010

Name: Human activin receptor-like kinase 1 (ALK1) kinase domain bound to LDN-193189
PDB Code: 3MY0
Target Class: Protein Kinase
Target: ACVRL1
Disease Area: cancer
Date Deposited: May 08 2010

Name: Human MYC induced nuclear antigen isoform 2
PDB Code: 2XDV
Target Class: Oxidoreductases
Target: MINA
Disease Area: cancer, chromatin and epigenetics, signalling
Date Deposited: May 07 2010

Name: Human type 1 tumor necrosis factor receptor shedding aminopeptidase regulator isoform a
PDB Code: 2XDT
Target Class: Proteases
Target: ERAP1
Disease Area: cancer, signalling
Date Deposited: May 07 2010

Name: Human phosphoglycerate mutase family member 5
PDB Code: 3MXO
Target Class: Phosphatases
Target: PGAM5
Disease Area: signalling
Date Deposited: May 07 2010

Name: Human JMJD2C tudor domain
PDB Code: 2XDP
Target Class: Oxidoreductases
Target: JMJD2C
Disease Area: cancer, chromatin and epigenetics
Date Deposited: May 06 2010

Name: Human Early B-cell factor 3 IPT/TIG domain and dimerisation helices
PDB Code: 3MUJ
Target Class: Miscellaneous
Target: EBF3
Disease Area: chromatin and epigenetics
Date Deposited: May 03 2010

Name: Human growth hormone releasing hormone receptor (extracellular domain)
PDB Code: 2XDG
Target Class: Membrane proteins
Target: GHRHR
Disease Area:
Date Deposited: Apr 30 2010

[?]

Name: ACVR1 (ALK2) kinase in complex with a 2-aminopyridine inhibitor (K02288a)
PDB Code: 3MTF
Target Class: Protein Kinase
Target: ACVR1 + 2-aminopyridine inhibitor
Disease Area: cancer, signalling
Date Deposited: Apr 30 2010

Name: Human PCTAIRE protein kinase 1 in complex with Indirubin E804
PDB Code: 3MTL
Target Class: Protein Kinase
Target: PCTK1 + Indirubin E804
Disease Area: signalling
Date Deposited: Apr 30 2010

Name: Human ubiquitin specific peptidase 21 in complex with the ubiquitin variant UBV21.4
PDB Code: 3MTN
Target Class: Ubiquitylation
Target: USP21
Disease Area: signalling
Date Deposited: Apr 30 2010

Name: Human suppressor of variegation 3-9 homolog 1, chromodomain
PDB Code: 3MTS
Target Class: Methyl-lysine readers
Target: SUV39H1
Disease Area: chromatin and epigenetics
Date Deposited: Apr 30 2010

Name: Crystal Structure of INPP5B in complex with phosphatidylinositol 4-phosphate
PDB Code: 3MTC
Target Class: Phosphoinosotide dependent signalling
Target: INPP5B
Disease Area: signalling
Date Deposited: Apr 30 2010

Name: Human S-adenosylhomocysteine hydrolase-like protein 1 in complex with NAD
PDB Code: 3MTG
Target Class: AA metabolic enzymes
Target: AHCYL1
Disease Area: cancer, metabolism
Date Deposited: Apr 30 2010

Name: Human H2A histone family, member Y2
PDB Code: 2XD7
Target Class: Miscellaneous
Target: H2AFY2
Disease Area:
Date Deposited: Apr 29 2010

Name: Human gamma-butyrobetaine hydroxylase; gamma-butyrobetaine, 2-oxoglutarate dioxygenase 1
PDB Code: 3MS5
Target Class: Oxidoreductases
Target: BBOX1
Disease Area: metabolism
Date Deposited: Apr 29 2010

Name: Plasmodium falciparum CDPK6 (PF11_0239), C-terminal domain
PDB Code: 3MSE
Target Class: Protein Kinase
Target: CDPK6
Disease Area: parasitic disease
Date Deposited: Apr 29 2010

Name: Human bromodomain of ash1 (absent, small, or homeotic)-like
PDB Code: 3MQM
Target Class: Bromodomain
Target: ASH1L
Disease Area: chromatin and epigenetics, signalling
Date Deposited: Apr 28 2010

Name: Human Early B-cell factor 1 IPT/TIG domain
PDB Code: 3MQI
Target Class: Miscellaneous
Target: EBF1
Disease Area: chromatin and epigenetics
Date Deposited: Apr 28 2010

Name: Human FYVE, RhoGEF and PH domain containing 5
PDB Code: 3MPX
Target Class: G-Protein Regulators
Target: FGD5
Disease Area: signalling
Date Deposited: Apr 27 2010

Name: Human metabotropic glutamate receptor 7, extracellular ligand binding domain, in complex with antagonist LY341495
PDB Code: 3MQ4
Target Class: Membrane proteins
Target: GRM7
Disease Area: neurobiology
Date Deposited: Apr 27 2010

Name: Human Lamin-B1 coil 2 Segment
PDB Code: 3MOV
Target Class: Miscellaneous
Target: LMNB1
Disease Area:
Date Deposited: Apr 23 2010

Name: Human bromodomain and PHD finger containing 1, PWWP domain in complex with H3K36me3
PDB Code: 3MO8
Target Class: Methyl-lysine readers
Target: BRPF1
Disease Area: chromatin and epigenetics
Date Deposited: Apr 22 2010

Name: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
PDB Code: 3MHK
Target Class: Poly ADP-ribose polymerase
Target: TNKS2
Disease Area: cancer
Date Deposited: Apr 08 2010

Name: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
PDB Code: 3MHJ
Target Class: Poly ADP-ribose polymerase
Target: TNKS2
Disease Area: cancer
Date Deposited: Apr 08 2010

Name: Human carbonic anhydrase VII [isoform 1]
PDB Code: 3MDZ
Target Class: Miscellaneous
Target: CA7
Disease Area: neurobiology
Date Deposited: Mar 31 2010

Name: Human ankyrin repeat and SOCS box protein 9 in complex with Elongin BC
PDB Code: 2XAI
Target Class: Signalling proteins
Target: ASB9 + Elongin BC
Disease Area:
Date Deposited: Mar 31 2010

Name: Human bone morphogenic protein receptor type I B (BMPR1B) in complex with FKBP12 and LDN-193189
PDB Code: 3MDY
Target Class: Protein Kinase
Target: BMPR1B + FKBP12 + LDN-193189
Disease Area:
Date Deposited: Mar 31 2010

Name: Cryptosporidium parvum choline kinase in complex with Decamethonium bromide and KNa-Tartrate
PDB Code: 3MES
Target Class: Non-protein Kinase
Target: CpChK
Disease Area: parasitic disease
Date Deposited: Mar 31 2010

Name: Cryptosporidium parvum pyruvate kinase (cgd1_2040) in complex with citrate
PDB Code: 3MA8
Target Class: Non-protein Kinase
Target: PYRK1
Disease Area: parasitic disease
Date Deposited: Mar 31 2010

Name: Human coiled-coil domain containing 101, SGF29 tudor-like domain, in complex with H3K4Me2
PDB Code: 3MET
Target Class: Methyl-lysine readers
Target: CCDC101
Disease Area: chromatin and epigenetics
Date Deposited: Mar 31 2010

Name: Human coiled-coil domain containing 101, SGF29 tudor-like domain, in complex with H3R2me2sK4me3
PDB Code: 3MEU
Target Class: Methyl-lysine readers
Target: CCDC101
Disease Area: chromatin and epigenetics
Date Deposited: Mar 31 2010

Name: Human coiled-coil domain containing 101, SGF29 tudor-like domain, in complex with H3[R2A]K4me3
PDB Code: 3MEV
Target Class: Methyl-lysine readers
Target: CCDC101
Disease Area: chromatin and epigenetics
Date Deposited: Mar 31 2010

Name: Human SET and MYND domain containing 3, methyltransferase domain, in complex with S-adenosyl-methionine
PDB Code: 3MEK
Target Class: Transferases
Target: SMYD3
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Mar 31 2010

Name: Human pyruvate kinase M2 in complex with soluble activator
PDB Code: 3ME3
Target Class: Non-protein Kinase
Target: PKM2
Disease Area: cancer
Date Deposited: Mar 31 2010

Name: Human coiled-coil domain containing 101, SGF29 tudor-like domain, in complex with H3K4me3
PDB Code: 3ME9
Target Class: Methyl-lysine readers
Target: CCDC101
Disease Area: chromatin and epigenetics
Date Deposited: Mar 31 2010

Name: Human coiled-coil domain containing 101, SGF29 tudor-like domain, in complex with H3K4me3
PDB Code: 3MEA
Target Class: Methyl-lysine readers
Target: CCDC101
Disease Area: chromatin and epigenetics
Date Deposited: Mar 31 2010

Name: Human coiled-coil domain containing 101, SGF29 tudor-like domain
PDB Code: 3MEW
Target Class: Methyl-lysine readers
Target: CCDC101
Disease Area: chromatin and epigenetics
Date Deposited: Mar 30 2010

Name: Crystal structure of human diphosphoinositol polyphosphate phosphohydrolase 3-alpha
PDB Code: 3MCF
Target Class: Nucleotide metabolism
Target: NUDT10
Disease Area: signalling
Date Deposited: Mar 29 2010

Name: Human EPH receptor A2 ligand binding and cysteine-rich domains in complex with EPH receptor A1
PDB Code: 3MBW
Target Class: Protein Kinase
Target: EPHA2 EPHA1
Disease Area: cancer, signalling
Date Deposited: Mar 26 2010

Name: Human ubiquitin specific peptidase 7, UBL1 domain
PDB Code: 2KVR
Target Class: Ubiquitylation
Target: USP7
Disease Area: cancer
Date Deposited: Mar 26 2010

Name: Human polybromo 1 (5th bromodomain) in complex with NMP
PDB Code: 3MB4
Target Class: Bromodomain
Target: PB1 + NMP
Disease Area: cancer, chromatin and epigenetics, signalling
Date Deposited: Mar 25 2010

Name: Human pleckstrin homology domain interacting protein (2nd bromodomain)
PDB Code: 3MB3
Target Class: Bromodomain
Target: PHIP
Disease Area:
Date Deposited: Mar 25 2010

[?]

Name: Human Methionine-R-Sulfoxide Reductase B1 (MsrB1/ SEPX1)
PDB Code: 3MAO
Target Class: Oxidoreductases
Target: SEPX1
Disease Area:
Date Deposited: Mar 24 2010

Name: Toxoplasma gondii CDPK1 in complex with inhibitor 3BrB-PP1
PDB Code: 3MA6
Target Class: Protein Kinase
Target: TgCDPK1
Disease Area: parasitic disease
Date Deposited: Mar 23 2010

Name: Human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a naphtho-difuran ligand
PDB Code: 3MA3
Target Class: Protein Kinase
Target: PIM1 + consensus peptide + naphtho-difuran ligand
Disease Area: cancer, chromatin and epigenetics, signalling
Date Deposited: Mar 23 2010

Name: Human Nuclear Valosin containing protein Like (NVL), C-terminal AAA-ATPase domain
PDB Code: 2X8A
Target Class: ATPases
Target: NVL
Disease Area: neurobiology
Date Deposited: Mar 08 2010

Name: Human Early B-cell factor 1 DNA-binding domain
PDB Code: 3LYR
Target Class: Miscellaneous
Target: EBF1
Disease Area: chromatin and epigenetics
Date Deposited: Feb 28 2010

Name: Human MGC45594 in complex with NADP and fenoprofen (FUP)
PDB Code: 2X7H
Target Class: Oxidoreductases
Target: MGC45594 + NADP + fenoprofen (FUP)
Disease Area:
Date Deposited: Feb 26 2010

Name: Human SRPK2 (serine/arginine-rich protein-specific kinase 2)
PDB Code: 2X7G
Target Class: Protein Kinase
Target: SRPK2
Disease Area:
Date Deposited: Feb 26 2010

Name: Structure of Human TRAF2 and NCK interacting kinase (TNIK)
PDB Code: 2X7F
Target Class: Protein Kinase
Target: TNIK
Disease Area:
Date Deposited: Feb 26 2010

Name: Human DEAD-box RNA helicase DDX18, DEAD-domain
PDB Code: 3LY5
Target Class: DExD-DExH RNA helicases
Target: DDX18
Disease Area: cancer
Date Deposited: Feb 26 2010

Name: Human bromodomain containing 1, PWWP domain
PDB Code: 3LYI
Target Class: Methyl-lysine readers
Target: BRD1
Disease Area: chromatin and epigenetics
Date Deposited: Feb 26 2010

Name: Human GTPase IMAP family member 1, in complex with GDP
PDB Code: 3LXW
Target Class: GTPases
Target: GIMAP1
Disease Area: signalling
Date Deposited: Feb 25 2010

Name: Human GTPase IMAP family member 4, in complex with GDP
PDB Code: 3LXX
Target Class: GTPases
Target: GIMAP4
Disease Area: signalling
Date Deposited: Feb 25 2010

Name: Bromodomain of Human ATAD2B (AAA domain containing 2B)
PDB Code: 3LXJ
Target Class: Bromodomain
Target: KIAA1240
Disease Area:
Date Deposited: Feb 25 2010

Name: Human lens crystallin Beta-crystallin A4
PDB Code: 3LWK
Target Class: Miscellaneous
Target: CRYBA4
Disease Area: metabolism
Date Deposited: Feb 24 2010

Name: Human coiled-coil domain containing 101, SGF29 tudor-like domain
PDB Code: 3LX7
Target Class: Methyl-lysine readers
Target: CCDC101
Disease Area: chromatin and epigenetics
Date Deposited: Feb 24 2010

Name: Human M-phase phosphoprotein 8, chromodomain
PDB Code: 3LWE
Target Class: Methyl-lysine readers
Target: MPHOSPH8
Disease Area: chromatin and epigenetics
Date Deposited: Feb 24 2010

Name: Crystal structure of human PIK3C3 in complex with 3-[4-(4-Morpholinyl)thieno[3,2-d]pyrimidin-2-yl]-phenol (Compound 15E)
PDB Code: 3LS8
Target Class: Phosphoinosotide dependent signalling
Target: PIK3C3
Disease Area: cancer, signalling
Date Deposited: Feb 12 2010

Name: Human ZC3HAV1 (ARTD13), C-terminal PARP domain
PDB Code: 2X5Y
Target Class: Poly ADP-ribose polymerase
Target: ZC3HAV1
Disease Area: cancer
Date Deposited: Feb 11 2010

Name: Human Vasoactive Intestinal Peptide Receptor 2 - GPCR extracellular domain
PDB Code: 2X57
Target Class: Membrane proteins
Target: VIPR2 (GPCR extracellular domain)
Disease Area:
Date Deposited: Feb 05 2010

[?]

Name: Human ubiquitin specific peptidase 15, DUSP domain
PDB Code: 3LMN
Target Class: Ubiquitylation
Target: USP15
Disease Area: cancer, signalling
Date Deposited: Jan 31 2010

Name: Human metabotropic glutamate receptor 5, extracellular ligand binding domain, in complex with glutamate
PDB Code: 3LMK
Target Class: Membrane proteins
Target: GRM5
Disease Area: neurobiology
Date Deposited: Jan 30 2010

Name: Plasmodium falciparum Lammer (PF14_0431), kinase domain, in complex with AMP-PNP
PDB Code: 3LLT
Target Class: Protein Kinase
Target: LAMMER
Disease Area: parasitic disease
Date Deposited: Jan 29 2010

Name: Human DNA (cytosine-5-)-methyltransferase 3 alpha, PWWP domain
PDB Code: 3LLR
Target Class: Transferases
Target: DNMT3A
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Jan 29 2010

Name: Human Ras-related GTP binding C, Ras domain, bound to GMP-PNP
PDB Code: 3LLU
Target Class: GTPases
Target: RRAGC
Disease Area: cancer, signalling
Date Deposited: Jan 29 2010

Name: Human Serine/Threonine Kinase 17B (STK17B) in complex with the kinase compound Quercetin
PDB Code: 3LM5
Target Class: Protein Kinase
Target: STK17B + Quercetin
Disease Area: signalling
Date Deposited: Jan 29 2010

Name: Human Serine/Threonine Kinase 17B (STK17B) in complex with the kinase compound ASC68
PDB Code: 3LM0
Target Class: Protein Kinase
Target: STK17B + ASC68
Disease Area: signalling
Date Deposited: Jan 29 2010

Name: Human Myosin Light Chain Kinase Family Member 4
PDB Code: 2X4F
Target Class: Protein Kinase
Target: LOC340156
Disease Area: signalling
Date Deposited: Jan 29 2010

Name: Human phospholysine phosphohistidine inorganic pyrophosphate phosphatase LHPP
PDB Code: 2X4D
Target Class: Miscellaneous
Target: LHPP
Disease Area: metabolism, signalling, neurobiology
Date Deposited: Jan 29 2010

Name: DEAH (Asp-Glu-Ala-His box polypeptide 9 isoform 1
PDB Code: 3LLM
Target Class: DExD-DExH RNA helicases
Target: DHX9
Disease Area: cancer
Date Deposited: Jan 29 2010

Name: Human cyclin G associated kinase
PDB Code: 3LL6
Target Class: Protein Kinase
Target: GAK
Disease Area: cancer, signalling
Date Deposited: Jan 29 2010

Name: Human macro domain 1
PDB Code: 2X47
Target Class: Miscellaneous
Target: MACROD1
Disease Area: metabolism, chromatin and epigenetics, signalling
Date Deposited: Jan 28 2010

[?]

Name: Human centaurin alpha-1, full-length, in complex with head group of PIP3
PDB Code: 3LJU
Target Class: G-Protein Regulators
Target: CENTA1
Disease Area: signalling
Date Deposited: Jan 26 2010

Name: Cryptosporidium parvum CDPK3 (cgd5_820), full-length, in complex with Ca2+ and AMPPNP
PDB Code: 3LIJ
Target Class: Protein Kinase
Target: CpCDPK3
Disease Area: parasitic disease
Date Deposited: Jan 25 2010

Name: Human aspartyl aminopeptidase
PDB Code: 3L6S
Target Class: Proteases
Target: DNPEP
Disease Area:
Date Deposited: Dec 24 2009

[?]

Name: An uncharacterised human oxidoreductase + raloxifene
PDB Code: 2X1H
Target Class: Oxidoreductases
Target: MGC45594 + raloxifene
Disease Area:
Date Deposited: Dec 24 2009

Name: C. parvum HSP70 (cgd2_20), ATP binding domain
PDB Code: 3L6Q
Target Class: ATPases
Target: CpHSP70
Disease Area: parasitic disease
Date Deposited: Dec 24 2009

Name: Human v-akt murine thymoma viral oncogene homolog 3, PH domain
PDB Code: 2X18
Target Class: Protein Kinase
Target: AKT3 (PH domain)
Disease Area: cancer, signalling, neurobiology
Date Deposited: Dec 22 2009

Name: Human haloacid dehalogenase-like hydrolase domain containing 1A
PDB Code: 3L5K
Target Class: Miscellaneous
Target: HDHD1A
Disease Area:
Date Deposited: Dec 22 2009

Name: Human glia maturation factor, gamma
PDB Code: 3L50
Target Class: Miscellaneous
Target: GMFG
Disease Area:
Date Deposited: Dec 21 2009

Name: Human HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1, 2nd WW domain
PDB Code: 3L4H
Target Class: Ubiquitylation
Target: HECW1
Disease Area: cancer
Date Deposited: Dec 20 2009

Name: C. parvum HSP70 (cgd2_20), ATP binding domain, in complex with ADP and inorganic phosphate
PDB Code: 3L4I
Target Class: ATPases
Target: CpHSP70
Disease Area: parasitic disease
Date Deposited: Dec 20 2009

Name: Human bromodomain and PHD finger containing 1, PWWP domain
PDB Code: 3L42
Target Class: Methyl-lysine readers
Target: BRPF1
Disease Area: chromatin and epigenetics
Date Deposited: Dec 18 2009

Name: Human dynamin 3, GTPase domain, in complex with GDP
PDB Code: 3L43
Target Class: GTPases
Target: DNM3
Disease Area: cancer
Date Deposited: Dec 18 2009

Name: Human epithelial cell transforming sequence 2 oncogene, second BRCT domain
PDB Code: 3L46
Target Class: G-Protein Regulators
Target: ECT2
Disease Area: cancer
Date Deposited: Dec 18 2009

Name: Cryptosporidium parvum CDPK3, cgd5_820, calcium binding domain
PDB Code: 3L19
Target Class: Protein Kinase
Target: CpCDPK3
Disease Area: parasitic disease
Date Deposited: Dec 11 2009

Name: Human NUDT16-like protein 1 (Syndesmos)
PDB Code: 3KVH
Target Class: Nucleotide metabolism
Target: NUDT16L1
Disease Area: cancer
Date Deposited: Nov 30 2009

Name: C. parvum HSP70 (cgd2_20), ATP binding domain + AMPPNP
PDB Code: 3KVG
Target Class: ATPases
Target: CpHSP70
Disease Area: parasitic disease
Date Deposited: Nov 30 2009

Name: Human hydroxysteroid dehydrogenase like 2
PDB Code: 3KVO
Target Class: Oxidoreductases
Target: SDHL
Disease Area:
Date Deposited: Nov 30 2009

[?]

Name: Vasopressin-activated calcium-mobilizing receptor-1
PDB Code: 2WZK
Target Class: Signalling proteins
Target: CUL5
Disease Area:
Date Deposited: Nov 30 2009

Name: Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 + indirubin
PDB Code: 3KVW
Target Class: Protein Kinase
Target: DYRK2 + indirubin
Disease Area: cancer, metabolism, signalling, neurobiology
Date Deposited: Nov 30 2009

Name: Human ring finger protein 168, ring finger domain
PDB Code: 3L11
Target Class: Ubiquitylation
Target: RNF168
Disease Area: cancer, neurobiology
Date Deposited: Nov 29 2009

Name: Human plexin C1, ubiquitin like domain
PDB Code: 3KUZ
Target Class: G-Protein Regulators
Target: PLXNC1
Disease Area: cancer
Date Deposited: Nov 28 2009

Name: Human chromobox homolog 3, chromo shadow domain
PDB Code: 3KUP
Target Class: Methyl-lysine readers
Target: CBX3
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Nov 27 2009

Name: Human deleted in liver cancer 1, RhoGAP domain
PDB Code: 3KUQ
Target Class: G-Protein Regulators
Target: DLC1
Disease Area: cancer
Date Deposited: Nov 27 2009

Name: Human EPH receptor A8, kinase domain
PDB Code: 3KUL
Target Class: Protein Kinase
Target: EPHA8
Disease Area: signalling
Date Deposited: Nov 27 2009

Name: Human fragile X mental retardation-related protein 1, Agenet domain
PDB Code: 3KUF
Target Class: Miscellaneous
Target: FXR1
Disease Area: signalling
Date Deposited: Nov 27 2009

Name: Toxoplasma gondii CDPK1, TGME49_101440, inactivated form
PDB Code: 3KU2
Target Class: Protein Kinase
Target: TgCDPK1
Disease Area: parasitic disease
Date Deposited: Nov 26 2009

Name: Human thioredoxin-like protein 2
PDB Code: 2WZ9
Target Class: Oxidoreductases
Target: TXNL2
Disease Area: cancer, signalling
Date Deposited: Nov 25 2009

Name: Human guanylate cyclase 1, soluble, beta 3
PDB Code: 2WZ1
Target Class: Miscellaneous
Target: GUCY1B3
Disease Area: cancer
Date Deposited: Nov 23 2009

Name: Human metabotropic glutamate receptor 1, extracellular ligand binding domain, in complex with the antagonist LY341495
PDB Code: 3KS9
Target Class: Ubiquitylation
Target: GRM1 + LY341495
Disease Area:
Date Deposited: Nov 20 2009

Name: Human Tankyrase-2, catalytic PARP domain
PDB Code: 3KR7
Target Class: Poly ADP-ribose polymerase
Target: Tankyrase-2
Disease Area: cancer
Date Deposited: Nov 18 2009

Name: Human Tankyrase-2, catalytic PARP domain in complex with inhibitor XAV939
PDB Code: 3KR8
Target Class: Poly ADP-ribose polymerase
Target: Tankyrase-2 + XAV939
Disease Area: cancer
Date Deposited: Nov 18 2009

Name: Human UDP-glucose dehydrogenase in complex with Uridine-5'-diphosphoglucose
PDB Code: 3KHU
Target Class: Oxidoreductases
Target: UGDH + S00790a
Disease Area: metabolism, signalling, neurobiology, drug metabolism and toxicology
Date Deposited: Oct 31 2009

Name: Human RecQ protein-like [isoform 1; tv1] in complex with double-stranded DNA
PDB Code: 2WWY
Target Class: Miscellaneous
Target: RECQL + dsDNA
Disease Area: chromatin and epigenetics
Date Deposited: Oct 31 2009

Name: Human EPH receptors A1 and A2, SAM domains complex
PDB Code: 3KKA
Target Class: Protein Kinase
Target: EPHA1 EPHA2
Disease Area: cancer, signalling
Date Deposited: Oct 30 2009

Name: Human ral guanine nucleotide dissociation stimulator, RAS-associating domain
PDB Code: 3KH0
Target Class: G-Protein Regulators
Target: RALGDS
Disease Area: cancer
Date Deposited: Oct 30 2009

[?]

Name: Human poly(ADP-ribose) polymerase 15, macro domain 2 in complex with adenosine-5-diphosphoribose
PDB Code: 3KH6
Target Class: Poly ADP-ribose polymerase
Target: PARP15 (macro domain)
Disease Area: cancer
Date Deposited: Oct 30 2009

Name: Human microtubule associated serine/threonine kinase 3 (PDZ domain)
PDB Code: 3KHF
Target Class: PDZ linkers
Target: MAST3 (PDZ domain)
Disease Area: signalling
Date Deposited: Oct 30 2009

Name: Human methylmalonic aciduria type A precursor in complex with GMP-PNP
PDB Code: 2WWW
Target Class: Miscellaneous
Target: MMAA + Z00118
Disease Area: metabolism, neurobiology
Date Deposited: Oct 30 2009

Name: Plasmodium falciparum pyruvate kinase (PFF1300w)
PDB Code: 3KHD
Target Class: Non-protein Kinase
Target: PYRK1
Disease Area: parasitic disease
Date Deposited: Oct 30 2009

Name: Toxoplasma gondii CDPK (541.m00134), calcium-loaded calmodulin-like domain
PDB Code: 3KHE
Target Class: Protein Kinase
Target: CDPK3
Disease Area: parasitic disease
Date Deposited: Oct 30 2009

Name: Human plant homeodomain finger protein 8
PDB Code: 2WWU
Target Class: Oxidoreductases
Target: PHF8
Disease Area: chromatin and epigenetics, neurobiology
Date Deposited: Oct 29 2009

[?]

Name: Human tight junction protein 3 (zona occludens 3), kinase domain
PDB Code: 3KFV
Target Class: Non-protein Kinase
Target: TJP3
Disease Area:
Date Deposited: Oct 28 2009

[?]

Name: Human prostaglandin-H2 D-isomerase
PDB Code: 2WWP
Target Class: Miscellaneous
Target: PTGDS
Disease Area: signalling
Date Deposited: Oct 26 2009

Name: Human poly(ADP-ribose) polymerase 2
PDB Code: 3KCZ
Target Class: Poly ADP-ribose polymerase
Target: PARP2
Disease Area: cancer
Date Deposited: Oct 22 2009

Name: The phox homology domain of human phosphoinositide-3-kinase-C2-gamma
PDB Code: 2WWE
Target Class: Phosphoinosotide dependent signalling
Target: PIK3C2G
Disease Area: cancer
Date Deposited: Oct 22 2009

Name: poly (ADP-ribose) polymerase 2, catalytic fragment in complex with ABT888
PDB Code: 3KJD
Target Class: Poly ADP-ribose polymerase
Target: PARP2 + ABT888
Disease Area: cancer
Date Deposited: Oct 22 2009

Name: Human hect domain and RLD 2, third RLD domain
PDB Code: 3KCI
Target Class: Ubiquitylation
Target: HERC2
Disease Area:
Date Deposited: Oct 21 2009

Name: Human EHMT2/G9a, methyltransferase domain, in complex with 2,4-Diamino-7-aminoalkoxy-quinazoline
PDB Code: 3K5K
Target Class: Transferases
Target: EHMT2
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Oct 07 2009

Name: Human sirtuin 6 in complex with adenosine-5-diphosphoribose
PDB Code: 3K35
Target Class: Miscellaneous
Target: SIRT6
Disease Area: chromatin and epigenetics
Date Deposited: Oct 01 2009

Name: Acyl-CoA thioesterase 4
PDB Code: 3K2I
Target Class: Lipid signalling
Target: ACOT4
Disease Area: metabolism
Date Deposited: Sep 30 2009

Name: Human cdc-2 like kinase 3 in complex with V25
PDB Code: 2WU7
Target Class: Protein Kinase
Target: CLK3 + V25
Disease Area: signalling, neurobiology
Date Deposited: Sep 30 2009

Name: Human cdc-2 like kinase 3 in complex with DKI
PDB Code: 2WU6
Target Class: Protein Kinase
Target: CLK3 + DKI
Disease Area: signalling, neurobiology
Date Deposited: Sep 30 2009

Name: Human polybromo 1 (3rd bromodomain)
PDB Code: 3K2J
Target Class: Bromodomain
Target: PB1
Disease Area: chromatin and epigenetics, signalling
Date Deposited: Sep 30 2009

Name: Human dual-specificity tyrosine phosphorylation regulated kinase 2
PDB Code: 3K2L
Target Class: Protein Kinase
Target: DYRK2
Disease Area:
Date Deposited: Sep 30 2009

Name: Human phosphatidylserine receptor beta
PDB Code: 3K2O
Target Class: Oxidoreductases
Target: PTDSR
Disease Area: signalling
Date Deposited: Sep 30 2009

[?]

Name: Plasmodium falciparum CDPK3 (PFC0420w), CAD domain
PDB Code: 3K21
Target Class: Protein Kinase
Target: CDPK3
Disease Area: parasitic disease
Date Deposited: Sep 29 2009

[?]

Name: Human haloacid dehalogenase-like hydrolase domain containing 3
PDB Code: 3K1Z
Target Class: Miscellaneous
Target: HDHD3
Disease Area:
Date Deposited: Sep 29 2009

Name: Human mucosa associated lymphoid tissue lymphoma translocation gene 1, tandem Ig domains
PDB Code: 3K0W
Target Class: Proteases
Target: MALT1
Disease Area: cancer
Date Deposited: Sep 25 2009

Name: Human intersectin 2, C2 domain
PDB Code: 3JZY
Target Class: G-Protein Regulators
Target: ITSN2
Disease Area: signalling, neurobiology
Date Deposited: Sep 24 2009

Name: Mouse ubiquitin specific peptidase 4 (proto-oncogene), N-terminal domains
PDB Code: 3JYU
Target Class: Ubiquitylation
Target: USP4
Disease Area: cancer
Date Deposited: Sep 22 2009

Name: Human dipeptidyl peptidase 7
PDB Code: 3JYH
Target Class: Proteases
Target: DPP7
Disease Area:
Date Deposited: Sep 21 2009

Name: Plasmodium falciparum SIR2A (PF13_0152) in complex with AMP
PDB Code: 3JWP
Target Class: Miscellaneous
Target: SIR2A
Disease Area: parasitic disease
Date Deposited: Sep 18 2009

[?]

Name: Human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90055
PDB Code: 3JTK
Target Class: Transferases
Target: NMT1
Disease Area: parasitic disease
Date Deposited: Sep 12 2009

Name: Human embryonic ectoderm development (EED) in complex with a trimethylated H4K20 peptide
PDB Code: 3JPX
Target Class: Miscellaneous
Target: EED
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Sep 04 2009

[?]

Name: Human PIM1 in complex with a consensus peptide and a pyrrolo-[2,3-a]carbazole
PDB Code: 3JPV
Target Class: Protein Kinase
Target: PIM1 + Pyrrolo-[2-3]carbazole
Disease Area: chromatin and epigenetics, signalling
Date Deposited: Sep 04 2009

Name: Human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD85646
PDB Code: 3IWE
Target Class: Transferases
Target: NMT1
Disease Area: parasitic disease
Date Deposited: Sep 02 2009

Name: 70kDa heat shock protein 5 (BiP) ATPase domain in complex with ADP
PDB Code: 3IUC
Target Class: ATPases
Target: HSPA5
Disease Area: cancer
Date Deposited: Aug 31 2009

Name: Human D4, zinc and double PHD fingers family 2 - zinc finger domain
PDB Code: 3IUF
Target Class: Miscellaneous
Target: DPF2
Disease Area: cancer
Date Deposited: Aug 31 2009

[?]

Name: Human Rho GTPase-activating protein
PDB Code: 3IUG
Target Class: G-Protein Regulators
Target: RICS
Disease Area: neurobiology
Date Deposited: Aug 31 2009

Name: Human IQ motif containing GTPase activating protein 3, C-terminal domain
PDB Code: 3ISU
Target Class: G-Protein Regulators
Target: IQGAP3
Disease Area: cancer, signalling
Date Deposited: Aug 31 2009

Name: Human tumor susceptibility gene 101, coiled-coil domain
PDB Code: 3IV1
Target Class: Ubiquitylation
Target: TSG101
Disease Area: cancer
Date Deposited: Aug 31 2009

Name: Human DEAD-box RNA helicase DDX53, DEAD-box domain in complex with AMP
PDB Code: 3IUY
Target Class: ATPases
Target: DDX53
Disease Area: cancer
Date Deposited: Aug 31 2009

Name: Human polybromo 1 (1st bromodomain)
PDB Code: 3IU5
Target Class: Bromodomain
Target: PB1
Disease Area: chromatin and epigenetics, signalling
Date Deposited: Aug 30 2009

Name: Human polybromo 1 (6th bromodomain)
PDB Code: 3IU6
Target Class: Bromodomain
Target: PB1
Disease Area: chromatin and epigenetics, signalling
Date Deposited: Aug 30 2009

Name: Human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90096
PDB Code: 3IU2
Target Class: Transferases
Target: NMT1
Disease Area: parasitic disease
Date Deposited: Aug 29 2009

Name: Human type-I N-myristoyltransferase with bound myristoyl-CoA
PDB Code: 3IU1
Target Class: Transferases
Target: NMT1
Disease Area: parasitic disease
Date Deposited: Aug 29 2009

Name: Human UDP-glucose dehydrogenase, apo form
PDB Code: 3ITK
Target Class: Oxidoreductases
Target: UGDH
Disease Area: metabolism, signalling, neurobiology, drug metabolism and toxicology
Date Deposited: Aug 28 2009

Name: Human 4-hydroxyphenylpyruvate dioxygenase
PDB Code: 3ISQ
Target Class: Oxidoreductases
Target: HPD
Disease Area:
Date Deposited: Aug 27 2009

Name: Toxoplasma gondii CDPK6, 38.m00014, kinase domain in complex with AMP-PNP
PDB Code: 3IS5
Target Class: Protein Kinase
Target: CDPK6
Disease Area: parasitic disease
Date Deposited: Aug 25 2009

Name: Human 3-hydroxyacyl-ACP dehydratase
PDB Code: 3IR3
Target Class: Miscellaneous
Target: HTD2
Disease Area:
Date Deposited: Aug 21 2009

Name: Human Sorting Nexin 7, phox homology (px) domain
PDB Code: 3IQ2
Target Class: Phosphoinosotide dependent signalling
Target: SNX7
Disease Area: signalling
Date Deposited: Aug 19 2009

Name: Human haspin in complex with 5-Iodotubercidin
PDB Code: 3IQ7
Target Class: Protein Kinase
Target: GSG2 + K00224
Disease Area: chromatin and epigenetics, signalling
Date Deposited: Aug 19 2009

Name: Human glutamate-oxaloacetate transaminase 1
PDB Code: 3II0
Target Class: Miscellaneous
Target: GOT1
Disease Area: metabolism
Date Deposited: Jul 31 2009

[?]

Name: Human kelch-like 7
PDB Code: 3II7
Target Class: Miscellaneous
Target: KLHL7
Disease Area:
Date Deposited: Jul 31 2009

Name: Human ubiquitin specific peptidase 5 in covalent complex with ubiquitin
PDB Code: 3IHP
Target Class: Ubiquitylation
Target: USP5
Disease Area: signalling
Date Deposited: Jul 31 2009

[?]

Name: Human centaurin gamma 3, RAS domain
PDB Code: 3IHW
Target Class: GTPases
Target: CENTG3
Disease Area: signalling
Date Deposited: Jul 31 2009

Name: Human PR domain-containing protein 10, methyltransferase domain
PDB Code: 3IHX
Target Class: Methyltransferases
Target: PRDM10
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Jul 31 2009

Name: Phosphoinositide-3-kinase, class 3
PDB Code: 3IHY
Target Class: Non-protein Kinase
Target: PIK3C3
Disease Area: cancer, signalling
Date Deposited: Jul 31 2009

Name: Human methyl-CpG binding domain protein 4, C-terminal glycosylase domain
PDB Code: 3IHO
Target Class: Miscellaneous
Target: MBD4
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Jul 30 2009

Name: Human alanine aminotransferase 2 in complex with PLP
PDB Code: 3IHJ
Target Class: AA metabolic enzymes
Target: GPT2
Disease Area: metabolism
Date Deposited: Jul 30 2009

Name: Human CTPS2 in complex with ADP
PDB Code: 3IHL
Target Class: Nucleotide metabolism
Target: CTPS2
Disease Area: cancer
Date Deposited: Jul 30 2009

Name: Cryptosporidium Parvum CDPK1, cgd3_920, in complex with AMPPNP
PDB Code: 3IGO
Target Class: Malaria
Target: CDPK1
Disease Area: parasitic disease
Date Deposited: Jul 28 2009

Name: Human IQ motif containing GTPase activating protein 2, RasGAP C-terminal (RGC) domain
PDB Code: 3IEZ
Target Class: G-Protein Regulators
Target: IQGAP2
Disease Area: cancer
Date Deposited: Jul 23 2009

Name: Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A in complex with consensus peptide
PDB Code: 2WO6
Target Class: Protein Kinase
Target: DYRK1A + consensus peptide
Disease Area: signalling, neurobiology
Date Deposited: Jul 22 2009

Name: Plasmodium falciparum HSP90, N-terminal domain, in complex with ADP analog
PDB Code: 3IED
Target Class: Miscellaneous
Target: HSP90
Disease Area: parasitic disease
Date Deposited: Jul 22 2009

[?]

Name: Human ribosomal protein S6 kinase, 90kDa, polypeptide 1
PDB Code: 2WNT
Target Class: Protein Kinase
Target: RPS6KA1
Disease Area: signalling, neurobiology
Date Deposited: Jul 20 2009

Name: Human OPRTASE domain of Uridine 5
PDB Code: 2WNS
Target Class: Nucleotide metabolism
Target: UMPS
Disease Area: metabolism
Date Deposited: Jul 19 2009

Name: Human E3 Ligase GRAIL, PA domain
PDB Code: 3ICU
Target Class: Ubiquitylation
Target: RNF128
Disease Area: metabolism, signalling
Date Deposited: Jul 18 2009

[?]

Name: Human adenosine deaminase
PDB Code: 3IAR
Target Class: Miscellaneous
Target: ADA
Disease Area: metabolism
Date Deposited: Jul 14 2009

Name: Human SH3 domain of LIM and SH3 domain protein 1
PDB Code: 3I35
Target Class: Cell-type specific expression
Target: LASP1
Disease Area: cancer, signalling
Date Deposited: Jun 30 2009

Name: human Homo sapiens heat shock 70kDa protein 2 (HSPA2)
PDB Code: 3I33
Target Class: ATPases
Target: HSPA2
Disease Area: cancer
Date Deposited: Jun 30 2009

Name: Human NmrA-like family domain containing 1 in complex with NADP and 2-(4-chloro-phenylamino)-nicotinic acid
PDB Code: 2WMD
Target Class: Oxidoreductases
Target: NMRAL1+ NADP + nicotinic acid
Disease Area: metabolism, signalling
Date Deposited: Jun 30 2009

Name: Human kelch-like 11
PDB Code: 3I3N
Target Class: BTB-Kelch
Target: KLHL11
Disease Area:
Date Deposited: Jun 30 2009

Name: Human E1A binding protein p300 (bromodomain)
PDB Code: 3I3J
Target Class: Bromodomain
Target: EP300 (bromodomain)
Disease Area: cancer, metabolism, chromatin and epigenetics, signalling, neurobiology
Date Deposited: Jun 30 2009

Name: Human magnesium-dependent phosphatase 1
PDB Code: 2WM8
Target Class: Miscellaneous
Target: MGC5987
Disease Area:
Date Deposited: Jun 30 2009

Name: Human WD repeat domain 92, WD repeats domain
PDB Code: 3I2N
Target Class: Miscellaneous
Target: WDR92
Disease Area: Cancer, Chromatin and Epigenetics
Date Deposited: Jun 30 2009

[?]

Name: Human chromobox homolog 5, chromo shadow Domain
PDB Code: 3I3C
Target Class: Methyl-lysine readers
Target: CBX5
Disease Area: Cancer, Chromatin and Epigenetics
Date Deposited: Jun 30 2009

Name: Human ubiquitin specific peptidase 21 in complex with Ubiquitin
PDB Code: 3I3T
Target Class: Ubiquitylation
Target: USP21
Disease Area: signalling
Date Deposited: Jun 30 2009

Name: Human ubiquilin 1, ubiquitin-like domain
PDB Code: 2KLC
Target Class: Ubiquitylation
Target: UBQLN1
Disease Area: neurobiology
Date Deposited: Jun 30 2009

Name: Human lanosterol 14alpha-demethylase (CYP51) in complex with ketoconazole
PDB Code: 3I3K
Target Class: Miscellaneous
Target: CYP51A1
Disease Area: drug metabolism and toxicology
Date Deposited: Jun 30 2009

Name: Human 6 pyruvoyl tetrahydrobiopterin synthase
PDB Code: 3I2B
Target Class: Miscellaneous
Target: PTS
Disease Area:
Date Deposited: Jun 29 2009

Name: Human NmrA-like family domain containing 1 in complex with NADP and niflumic acid
PDB Code: 2WM3
Target Class: Oxidoreductases
Target: NMRAL1 + NADP + niflumic acid
Disease Area: metabolism, signalling
Date Deposited: Jun 29 2009

Name: Human MOCS3, rhodanese-like domain
PDB Code: 3I2V
Target Class: Ubiquitylation
Target: MOCS3
Disease Area: Metabolism
Date Deposited: Jun 29 2009

Name: Toxoplasma gondii CDPK3, TGME49_105860
PDB Code: 3HZT
Target Class: Malaria
Target: CDPK3
Disease Area: Parasitic Disease
Date Deposited: Jun 24 2009

[?]

Name: Human RAB GTPase activating protein 1-like
PDB Code: 3HZJ
Target Class: G-Protein Regulators
Target: RABGAP1L
Disease Area: Cancer
Date Deposited: Jun 23 2009

Name: Toxoplasma gondii CDPK1, TGME49_101440, in presence of calcium
PDB Code: 3HX4
Target Class: Malaria
Target: CDPK1
Disease Area: Parasitic Disease
Date Deposited: Jun 19 2009

[?]

Name: Kinase domain of human VEGFR1
PDB Code: 3HNG
Target Class: Protein Kinase
Target: FLT1 (KINASE DOMAIN)
Disease Area: cancer
Date Deposited: May 31 2009

Name: Human DNA methyltransferase 1 associated protein 1, SANT domain
PDB Code: 3HM5
Target Class: Transferases
Target: DMAP1
Disease Area:
Date Deposited: May 30 2009

Name: Human Lamin B1
PDB Code: 3HN9
Target Class: Miscellaneous
Target: LMNB1
Disease Area:
Date Deposited: May 30 2009

Name: Human euchromatic histone methyltransferase 1 in complex with SAH and mono-Methylated H3K9 peptide
PDB Code: 3HNA
Target Class: Transferases
Target: EHMT1
Disease Area: chromatin and epigenetics
Date Deposited: May 30 2009

Name: Human bromodomain containing 9
PDB Code: 3HME
Target Class: Bromodomain
Target: BRD9
Disease Area: chromatin and epigenetics
Date Deposited: May 29 2009

Name: Human v-abl Abelson murine leukemia viral oncogene homolog 2 in complex with K00546
PDB Code: 3HMI
Target Class: Protein Kinase
Target: ABL2 + K00546
Disease Area: cancer, signalling, neurobiology
Date Deposited: May 29 2009

[?]

Name: Human TAF1-like RNA polymerase II (bromodomain)
PDB Code: 3HMH
Target Class: Bromodomain
Target: TAF1L
Disease Area:
Date Deposited: May 29 2009

Name: Human polybromo 1 (2nd bromodomain)
PDB Code: 3HMF
Target Class: Bromodomain
Target: PB1
Disease Area: cancer, chromatin and epigenetics, signalling
Date Deposited: May 29 2009

Name: Human haloacid dehalogenase-like hydrolase domain containing 2
PDB Code: 3HLT
Target Class: Miscellaneous
Target: HDHD2
Disease Area:
Date Deposited: May 29 2009

Name: Human plexin B1, cytoplasminc domain
PDB Code: 3HM6
Target Class: G-Protein Regulators
Target: PLXNB1
Disease Area: Cancer
Date Deposited: May 28 2009

[?]

Name: Human hexokinase 3, C-terminal hexokinase domain
PDB Code: 3HM8
Target Class: Non-protein Kinase
Target: HK3
Disease Area: Metabolism
Date Deposited: May 28 2009

[?]

Name: Human Poly (ADP-ribose) Polymerase 10, catalytic domain in complex with an inhibitor 3-Aminobenzamide
PDB Code: 3HKV
Target Class: Poly ADP-ribose polymerase
Target: PARP10
Disease Area: cancer
Date Deposited: May 26 2009

Name: Cryptosporidium Parvum calcium dependent protein kinase cgd7_40, kinase domain in complex with ANP
PDB Code: 3HKO
Target Class: Malaria
Target: CpCDPK4-Pk (cgd7_40)
Disease Area:
Date Deposited: May 25 2009

Name: Leishmania Major HSP90, middle and C-terminal domain
PDB Code: 3HJC
Target Class: Miscellaneous
Target: LmHSP90
Disease Area:
Date Deposited: May 21 2009

Name: Human Ephrin receptor EPHA1, SAM domain
PDB Code: 3HIL
Target Class: Protein Kinase
Target: EPHA1
Disease Area:
Date Deposited: May 20 2009

Name: Human acyl-CoA binding domain 4 in complex with stearoyl-CoA
PDB Code: 2WH5
Target Class: Miscellaneous
Target: ACBD4 + stearoyl-CoA
Disease Area:
Date Deposited: Apr 30 2009

Name: Human sperm-specific glyceraldehyde-3-phosphate dehydrogenase complex with NAD and phosphate
PDB Code: 3H9E
Target Class: Oxidoreductases
Target: GAPDHS
Disease Area: metabolism
Date Deposited: Apr 30 2009

Name: Human TTK protein kinase in complex with a pyrimido-diazepin ligand
PDB Code: 3H9F
Target Class: Protein Kinase
Target: TTK + pyrimido-diazepin ligand
Disease Area: cancer, signalling
Date Deposited: Apr 30 2009

Name: Human type I activin receptor (kinase domain) in complex with FKBP12 and dorsomorphin
PDB Code: 3H9R
Target Class: Protein Kinase
Target: ACVR1 + FKBP12 + dorsomorphin
Disease Area:
Date Deposited: Apr 30 2009

[?]

Name: S-adenosyl homocysteine hydrolase (SAHH) from Trypanosoma brucei
PDB Code: 3H9U
Target Class: AA metabolic enzymes
Target: TBSAH
Disease Area: parasitic disease
Date Deposited: Apr 30 2009

Name: human nudix (nucleoside diphosphate linked moiety X)-type motif 6, C-terminal domain
PDB Code: 3H95
Target Class: Nucleotide metabolism
Target: NUDT6
Disease Area: cancer
Date Deposited: Apr 30 2009

Name: Human ring finger protein 2, C-terminal domain
PDB Code: 3H8H
Target Class: Ubiquitylation
Target: RNF2
Disease Area: Cancer, Chromatin and Epigenetics
Date Deposited: Apr 29 2009

[?]

Name: Human ephrin type-A receptor 7, SAM domain
PDB Code: 3H8M
Target Class: Protein Kinase
Target: EPHA7
Disease Area: Cancer, Signalling
Date Deposited: Apr 29 2009

Name: Human ubiquitin-like modifier activating enzyme 5 in complex with ATP
PDB Code: 3H8V
Target Class: Ubiquitylation
Target: UBA5
Disease Area: Signalling
Date Deposited: Apr 29 2009

[?]

Name: Human fragile X mental retardation, autosomal homolog 2, Tudor domains
PDB Code: 3H8Z
Target Class: Methyl-lysine readers
Target: FXR2
Disease Area: Cancer, Chromatin and Epigenetics
Date Deposited: Apr 29 2009

[?]

Name: Human chromobox homolog 2 in complex with H3K27 peptide
PDB Code: 3H91
Target Class: Methyl-lysine readers
Target: CBX2
Disease Area: Cancer, Chromatin and Epigenetics
Date Deposited: Apr 29 2009

Name: Human thioredoxin reductase 3 (glutaredoxin domain)
PDB Code: 3H8Q
Target Class: Oxidoreductases
Target: TXNRD3
Disease Area: metabolism
Date Deposited: Apr 29 2009

Name: Leishmania Major HSP90, N-terminal domain, in complex with ATP mimetic
PDB Code: 3H80
Target Class: Miscellaneous
Target: LmHSP90
Disease Area: parasitic disease
Date Deposited: Apr 28 2009

Name: Human Plexin-D1, ubiquitin-like domain
PDB Code: 3H6N
Target Class: G-Protein Regulators
Target: PLXND1
Disease Area: Cancer, Signalling
Date Deposited: Apr 24 2009

Name: Human pyruvate kinase, muscle, in complex with activator NCGC00031955
PDB Code: 3H6O
Target Class: Non-protein Kinase
Target: PKM2
Disease Area: Cancer
Date Deposited: Apr 23 2009

Name: Leishmania major N-myristoyltransferase in complex with myristoyl-CoA
PDB Code: 3H5Z
Target Class: Transferases
Target: LmNMT
Disease Area: parasitic disease
Date Deposited: Apr 22 2009

Name: Human Ribonucleotide Reductase R1 subunit (RRM1) in complex with dATP and Magnesium.
PDB Code: 2WGH
Target Class: Nucleotide metabolism
Target: RRM1
Disease Area: cancer
Date Deposited: Apr 19 2009

Name: Human s-adenosyl homocysteine hydrolase-like 2 protein (AHCYL2)
PDB Code: 3GVP
Target Class: AA metabolic enzymes
Target: KIAA0828
Disease Area: metabolism, cancer
Date Deposited: Mar 31 2009

Name: Human CAMK2D in complex with SU6656 and calmodulin
PDB Code: 2WEL
Target Class: Protein Kinase
Target: CAMK2D+SU6656+calmodulin
Disease Area: metabolism, chromatin and epigenetics, neurobiology
Date Deposited: Mar 31 2009

Name: Human v-abl Abelson murine leukemia viral oncogene homolog 2 in complex with imatinib (Gleevec)
PDB Code: 3GVU
Target Class: Protein Kinase
Target: ABL2 + imatinib (Gleevec)
Disease Area:
Date Deposited: Mar 31 2009

[?]

Name: Human pyruvate kinase, muscle, in complex with Aps03-54
PDB Code: 3GQY
Target Class: Non-protein Kinase
Target: PKM2
Disease Area: Cancer
Date Deposited: Mar 31 2009

Name: Human pyruvate kinase, muscle, in complex with MBB01-45
PDB Code: 3GR4
Target Class: Non-protein Kinase
Target: PKM2
Disease Area: Cancer
Date Deposited: Mar 31 2009

Name: Human palmitoyl-protein thioesterase 1
PDB Code: 3GRO
Target Class: Miscellaneous
Target: PPT1
Disease Area:
Date Deposited: Mar 31 2009

[?]

Name: Cryptosporidium parvum calcium dependent protein kinase cgd3_920 in complex with 3-MB-PP1
PDB Code: 2WEI
Target Class: Malaria
Target: CpCDPK4
Disease Area: Parasitic Disease
Date Deposited: Mar 31 2009

Name: A functionally unannotated human medium-chain dehydrogenase/reductase in complex with diclofenac
PDB Code: 2WEK
Target Class: Oxidoreductases
Target: MGC45594 + diclofenac
Disease Area:
Date Deposited: Mar 31 2009

Name: Human ubiquitin-like modifier activating enzyme 5 in complex with AMPPNP
PDB Code: 3GUC
Target Class: Ubiquitylation
Target: UBA5
Disease Area: Signalling
Date Deposited: Mar 30 2009

[?]

Name: Human 3’ (2’), 5’-bisphosphate nucleotidase 1 (BPNT1) in complex with AMP, Mg and PO4
PDB Code: 2WEF
Target Class: Nucleotide metabolism
Target: BPNT1
Disease Area: neurobiology
Date Deposited: Mar 30 2009

Name: Human chromobox homolog 6 in complex with H3K9 peptide
PDB Code: 3GV6
Target Class: Methyl-lysine readers
Target: CBX6
Disease Area: Chromatin and Epigenetics
Date Deposited: Mar 30 2009

Name: Human HDAC6 zinc finger domain in complex with ubiquitin C-terminal peptide RLRGG
PDB Code: 3GV4
Target Class: Miscellaneous
Target: HDAC6
Disease Area: Cancer, Chromatin and Epigenetics
Date Deposited: Mar 30 2009

Name: Trypanosoma brucei UDP-glucose phosphorylase
PDB Code: 3GUE
Target Class: Miscellaneous
Target: Tb10.389.0330
Disease Area: Metabolism, parasitic disease
Date Deposited: Mar 29 2009

[?]

Name: Human Poly (ADP-ribose) Polymerase 14, catalytic domain in complex with an inhibitor 3-Aminobenzamide
PDB Code: 3GOY
Target Class: Poly ADP-ribose polymerase
Target: PARP14
Disease Area: cancer
Date Deposited: Mar 20 2009

Name: Human mitogen-activated protein kinase 11 in complex with nilotinib
PDB Code: 3GP0
Target Class: Protein Kinase
Target: MAPK11+ nilotinib
Disease Area: signalling
Date Deposited: Mar 20 2009

Name: Human MST4 (Mst3 and SOK1-related kinase)
PDB Code: 3GGF
Target Class: Protein Kinase
Target: MST4
Disease Area: cancer
Date Deposited: Feb 28 2009

[?]

Name: Human PDZ domain protein GIPC2
PDB Code: 3GGE
Target Class: Linkers
Target: GIPC2
Disease Area: signalling
Date Deposited: Feb 28 2009

Name: Human putative acyl-CoA dehydrogenase 11
PDB Code: 2WBI
Target Class: Oxidoreductases
Target: ACAD11
Disease Area:
Date Deposited: Feb 28 2009

Name: Human p300/CBP-associated factor (PCAF) - bromodomain
PDB Code: 3GG3
Target Class: Bromodomain
Target: PCAF
Disease Area: cancer, chromatin and epigenetics, signalling, neurobiology
Date Deposited: Feb 27 2009

Name: Human TTK protein kinase in complex with pyrrolopyridine
PDB Code: 3GFW
Target Class: Protein Kinase
Target: TTK + pyrrolopyridine
Disease Area: cancer, signalling
Date Deposited: Feb 27 2009

[?]

Name: Human NUDT18, NUDIX domain
PDB Code: 3GG6
Target Class: Nucleotide metabolism
Target: NUDT18
Disease Area:
Date Deposited: Feb 27 2009

Name: Human FK506-binding protein 3
PDB Code: 2KFV
Target Class: Isomerases
Target: FKBP3
Disease Area:
Date Deposited: Feb 27 2009

Name: Toxoplasma gondii pyruvate kinase
PDB Code: 3GG8
Target Class: Non-protein Kinase
Target: 55.m00007
Disease Area: Parasitic Disease
Date Deposited: Feb 27 2009

Name: Human Poly(ADP-ribose) polymerase 15, catalytic fragment in complex with an inhibitor PJ34
PDB Code: 3GEY
Target Class: Poly ADP-ribose polymerase
Target: PARP15 + PJ34
Disease Area: cancer
Date Deposited: Feb 26 2009

Name: Human Intersectin 2, RhoGEF domain
PDB Code: 3GF9
Target Class: G-Protein Regulators
Target: ITSN2
Disease Area: Neurobiology, Signalling
Date Deposited: Feb 26 2009

[?]

Name: Human histone-binding protein RBBP4
PDB Code: 3GFC
Target Class: Miscellaneous
Target: RBBP4
Disease Area:
Date Deposited: Feb 26 2009

Name: Human heat shock 70 kDa protein 1-like, ATP-ase domain in complex with ADP
PDB Code: 3GDQ
Target Class: ATPases
Target: HSPA1L
Disease Area:
Date Deposited: Feb 24 2009

Name: Human kinesin KIF13B, motor domain, in complex with ADP
PDB Code: 3GBJ
Target Class: Miscellaneous
Target: KIF13B
Disease Area: Cancer, Neurobiology
Date Deposited: Feb 19 2009

[?]

Name: Human pyruvate kinase, muscle, S437Y variant
PDB Code: 3G2G
Target Class: Non-protein Kinase
Target: PKM2
Disease Area: Cancer
Date Deposited: Jan 31 2009

[?]

Name: Human melanoma antigen family A, 4
PDB Code: 2WA0
Target Class: Miscellaneous
Target: MAGEA4
Disease Area: cancer, signalling
Date Deposited: Jan 31 2009

Name: Human bone morphogenetic protein receptor, type II (serine/threonine kinase) [isoform 1 precursor]
PDB Code: 3G2F
Target Class: Protein Kinase
Target: BMPR2
Disease Area: cancer
Date Deposited: Jan 31 2009

Name: Human SET domain-containing protein 2, methyltransferase domain, in complex with SAM
PDB Code: 3H6L
Target Class: Transferases
Target: SETD2
Disease Area:
Date Deposited: Jan 31 2009

Name: Human glutaredoxin 5 with iron-sulphur cluster
PDB Code: 2WEM
Target Class: Oxidoreductases
Target: GLRX5
Disease Area: metabolism
Date Deposited: Jan 31 2009

Name: Human HECT, UBA and WWE domain containing 1
PDB Code: 3G1N
Target Class: Ubiquitylation
Target: HUWE1
Disease Area:
Date Deposited: Jan 30 2009

Name: Leishmania major S-adenosylhomocysteine hydrolase
PDB Code: 3G1U
Target Class: Miscellaneous
Target: LMSAH
Disease Area: parasitic disease
Date Deposited: Jan 30 2009

Name: Human HERC2 E3 ligase, cytochrome-b5-like domain
PDB Code: 2KEO
Target Class: Ubiquitylation
Target: HERC2
Disease Area:
Date Deposited: Jan 30 2009

Name: Human Dead-box RNA helicase DDX19, in complex with an ATP-analogue and RNA
PDB Code: 3G0H
Target Class: ATPases
Target: DDX19
Disease Area: cancer
Date Deposited: Jan 28 2009

Name: Human bromodomain adjacent to zinc finger domain, 2B
PDB Code: 3G0L
Target Class: Bromodomain
Target: BAZ2B
Disease Area:
Date Deposited: Jan 28 2009

[?]

Name: Human polybromo 1 (5th bromodomain)
PDB Code: 3G0J
Target Class: Bromodomain
Target: PB1
Disease Area:
Date Deposited: Jan 28 2009

Name: Human bicoid-interacting protein 3 homolog, methyltransferase domain in complex with SAM
PDB Code: 3G07
Target Class: Transferases
Target: MEPCE
Disease Area:
Date Deposited: Jan 27 2009

Name: Human zinc binding alcohol dehydrogenase, domain containing 1 in complex with phenylbutazone
PDB Code: 2W98
Target Class: Oxidoreductases
Target: ZADH1 + phenylbutazone
Disease Area: metabolism
Date Deposited: Jan 22 2009

Name: Human NUDT6, N-terminal domain
PDB Code: 3FXT
Target Class: Nucleotide metabolism
Target: NUDT6
Disease Area: cancer
Date Deposited: Jan 21 2009

Name: Human dipeptidyl peptidase III
PDB Code: 3FVY
Target Class: Proteases
Target: DPP3
Disease Area:
Date Deposited: Jan 16 2009

Name: Plasmodium falciparum putative bolA-like protein PFE0790c
PDB Code: 2KDN
Target Class: Miscellaneous
Target: PFE0790c
Disease Area: Parasitic Disease
Date Deposited: Jan 12 2009

[?]

Name: Human homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 2
PDB Code: 2KDB
Target Class: Ubiquitylation
Target: HERPUD2
Disease Area:
Date Deposited: Jan 06 2009

Name: Trypanosoma brucei CTP synthetase - glutaminase domain in complex with acivicin
PDB Code: 2W7T
Target Class: Nucleotide metabolism
Target: TBCTPS
Disease Area: parasitic disease
Date Deposited: Dec 30 2008

[?]

Name: Human sorting nexin-17, PX domain
PDB Code: 3FOG
Target Class: Phosphoinosotide dependent signalling
Target: SNX17
Disease Area:
Date Deposited: Dec 30 2008

[?]

Name: Human DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B), PWWP domain
PDB Code: 3FLG
Target Class: Transferases
Target: DNMT3B
Disease Area:
Date Deposited: Dec 29 2008

Name: Human START domain of Acyl-coenzyme A thioesterase 11
PDB Code: 3FO5
Target Class: Lipid signalling
Target: ACOT11
Disease Area:
Date Deposited: Dec 27 2008

[?]

Name: Human microtubule associated serine/threonine kinase 4 (1st PDZ domain)
PDB Code: 2W7R
Target Class: Linkers
Target: MAST4 (1st PDZ domain)
Disease Area:
Date Deposited: Dec 24 2008

Name: Human mitogen-activated protein kinase kinase 6 in complex with K00207
PDB Code: 3FME
Target Class: Protein Kinase
Target: MAP2K6
Disease Area:
Date Deposited: Dec 21 2008

Name: Human haspin in complex with an isoquinoline
PDB Code: 3FMD
Target Class: Protein Kinase
Target: GSG2 + K00084
Disease Area: chromatin and epigenetics, signalling
Date Deposited: Dec 21 2008

[?]

Name: Human acyl-Coenzyme A binding domain containing 5 in complex with stearoyl-CoA
PDB Code: 3FLV
Target Class: Miscellaneous
Target: ACBD5 + stearoyl-CoA
Disease Area:
Date Deposited: Dec 19 2008

Name: Human WD40 protein CIAO1
PDB Code: 3FM0
Target Class: Miscellaneous
Target: CIAO1
Disease Area:
Date Deposited: Dec 19 2008

Name: Human full-length centaurin alpha-1 in complex with the FHA domain of KIF13B
PDB Code: 3FM8
Target Class: G-Protein Regulators
Target: CENTA1
Disease Area: Signalling
Date Deposited: Dec 19 2008

Name: Plasmodium Falciparum choline kinase PF14_0020 in complex with ADP
PDB Code: 3FI8
Target Class: Non-protein Kinase
Target: PfChK
Disease Area: Parasitic Disease
Date Deposited: Dec 18 2008

Name: Human UHRF1, RING domain
PDB Code: 3FL2
Target Class: Ubiquitylation
Target: UHRF1
Disease Area:
Date Deposited: Dec 18 2008

Name: Human Ephrin receptor EPHA2, Ectodomain
PDB Code: 3FL7
Target Class: Protein Kinase
Target: EPHA2
Disease Area: Cancer, Signalling
Date Deposited: Dec 18 2008

Name: Plasmodium falciparum bromodomain-containing protein PF10_0328
PDB Code: 3FKM
Target Class: Bromodomain
Target: PF10_0328
Disease Area: chromatin and epigenetics, parasitic disease
Date Deposited: Dec 17 2008

Name: Human kaiso
PDB Code: 3FKC
Target Class: BTB-Kelch
Target: ZBTB33
Disease Area: metabolism, cancer, chromatin and epigenetics, signalling, neurobiology
Date Deposited: Dec 16 2008

Name: Human human glucocorticoid receptor DNA-binding factor 1, RhoGAP domain
PDB Code: 3FK2
Target Class: G-Protein Regulators
Target: GRLF1
Disease Area: Cancer, Signalling
Date Deposited: Dec 15 2008

Name: Human zinc binding alcohol dehydrogenase, domain containing 1 in complex with 18beta-glycyrrhetinic acid
PDB Code: 2W4Q
Target Class: Oxidoreductases
Target: ZADH1
Disease Area:
Date Deposited: Nov 30 2008

Name: Human choline kinase beta in complex with phosphorylated hemicholinium-3 and adenosine nucleotide
PDB Code: 3FEG
Target Class: Non-protein Kinase
Target: CHKB
Disease Area: Metabolism
Date Deposited: Nov 30 2008

Name: Human centaurin alpha-1
PDB Code: 3FEH
Target Class: G-Protein Regulators
Target: CENTA1
Disease Area: Signalling
Date Deposited: Nov 30 2008

Name: Human tudor and KH domain containing
PDB Code: 3FDR
Target Class: Methyl-lysine readers
Target: TDRD2
Disease Area:
Date Deposited: Nov 30 2008

Name: Human chromobox homolog 5 (CBX5) in complex with H3K9(me)3 peptide
PDB Code: 3FDT
Target Class: Methyl-lysine readers
Target: CBX5
Disease Area:
Date Deposited: Nov 30 2008

Name: Human MBT domain containing 1
PDB Code: 3FEO
Target Class: Methyl-lysine readers
Target: MBTD1
Disease Area:
Date Deposited: Nov 30 2008

Name: Human dCMP deaminase
PDB Code: 2W4L
Target Class: Nucleotide metabolism
Target: DCTD
Disease Area: cancer
Date Deposited: Nov 28 2008

[?]

Name: Human N-acetylneuraminic acid phosphatase
PDB Code: 2W4M
Target Class: Miscellaneous
Target: NANP
Disease Area:
Date Deposited: Nov 28 2008

Name: human calcium/calmodulin-dependent protein kinase IV in complex with K00546
PDB Code: 2W4O
Target Class: Protein Kinase
Target: CAMK4
Disease Area: signalling
Date Deposited: Nov 28 2008

[?]

Name: Human DEAD box RNA helicase DDX5 (p68)
PDB Code: 3FE2
Target Class: ATPases
Target: DDX5
Disease Area: cancer
Date Deposited: Nov 27 2008

[?]

Name: Human heat shock 70kDa protein 6 (HSP70B)
PDB Code: 3FE1
Target Class: ATPases
Target: HSPA6
Disease Area: cancer
Date Deposited: Nov 27 2008

[?]

Name: Human carbonic anhydrase VI
PDB Code: 3FE4
Target Class: Miscellaneous
Target: CA6
Disease Area:
Date Deposited: Nov 27 2008

Name: Human SCRIB1 (1st PDZ domain)
PDB Code: 2W4F
Target Class: Linkers
Target: SCRIB1
Disease Area:
Date Deposited: Nov 25 2008

Name: Trypanosoma brucei acetyltransferase, Tb11.01.2886
PDB Code: 3FB3
Target Class: Transferases
Target: Tb11.01.2886
Disease Area: Parasitic Disease
Date Deposited: Nov 18 2008

Name: Trypanosoma brucei phosphomannosemutase, TB.10.700.370
PDB Code: 3F9R
Target Class: Transferases
Target: Tb10.70.0370
Disease Area: Parasitic Disease
Date Deposited: Nov 14 2008

Name: Cryptosporidium parvum calcium dependent protein kinase cgd7_1840 in complex with indirubin E804
PDB Code: 3F3Z
Target Class: Malaria
Target: CpCDPK8
Disease Area: parasitic disease
Date Deposited: Oct 31 2008

Name: Human choline kinase alpha in complex with hemicholinium-3
PDB Code: 3F2R
Target Class: Non-protein Kinase
Target: CHKA
Disease Area: cancer
Date Deposited: Oct 31 2008

Name: Human choline kinase alpha in complex with hemicholinium-3 and ADP
PDB Code: 3G15
Target Class: Non-protein Kinase
Target: CHKA
Disease Area: cancer
Date Deposited: Oct 31 2008

[?]

Name: Human carbonic anhydrase VIII
PDB Code: 2W2J
Target Class: Miscellaneous
Target: CA8
Disease Area:
Date Deposited: Oct 31 2008

Name: Human jumonji domain containing 2E in complex with 2,4-PDCA
PDB Code: 2W2I
Target Class: Miscellaneous
Target: JMJD2E (LOC390245) + 2,4-PDCA
Disease Area: chromatin and epigenetics
Date Deposited: Oct 31 2008

[?]

Name: Human lambda-crystallin in complex with NAD
PDB Code: 3F3S
Target Class: Miscellaneous
Target: CRYL1
Disease Area:
Date Deposited: Oct 31 2008

Name: Human Histone-lysine N-methyltransferase SETMAR, transposase domain
PDB Code: 3F2K
Target Class: Transferases
Target: SETMAR
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Oct 31 2008

Name: Human chromobox homolog 1 (CBX1)
PDB Code: 3F2U
Target Class: Methyl-lysine readers
Target: CBX1
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Oct 31 2008

Name: Human haspin in complex with an Imidazo-pyridazine ligand
PDB Code: 3F2N
Target Class: Protein Kinase
Target: GSG2 + K00508
Disease Area: chromatin and epigenetics, signalling
Date Deposited: Oct 30 2008

[?]

Name: Human SPRY domain-containing SOCS box protein SSB-1 in complex with peptide
PDB Code: 3F2O
Target Class: SOCS-box-containing
Target: SPSB1
Disease Area: signalling
Date Deposited: Oct 30 2008

[?]

Name: Human calcium/calmodulin-dependent protein kinase (CaM kinase) II delta - association domain
PDB Code: 2W2C
Target Class: Protein Kinase
Target: CAMK2D association domain
Disease Area: metabolism, signalling, neurobiology
Date Deposited: Oct 28 2008

Name: Human NUMB-like protein, phosphotyrosine interaction domain
PDB Code: 3F0W
Target Class: Miscellaneous
Target: NUMBL
Disease Area: neurobiology
Date Deposited: Oct 27 2008

[?]

Name: Plasmodium vivax geranylgeranylpyrophosphate synthase in complex with IPP and zoledronate
PDB Code: 3EZ3
Target Class: Transferases
Target: PvGGPPS
Disease Area: parasitic disease
Date Deposited: Oct 22 2008

[?]

Name: Human xenobiotic/medium-chain fatty acid:CoA ligase (L64P mutation) in complex with CoA
PDB Code: 3GPC
Target Class: Miscellaneous
Target: LOC148158
Disease Area: metabolism, drug metabolism and toxicology
Date Deposited: Oct 21 2008

Name: Human DEAD-box RNA-helicase DDX19 in complex with ADP
PDB Code: 3EWS
Target Class: ATPases
Target: DDX19
Disease Area: cancer
Date Deposited: Oct 16 2008

[?]

Name: Human RNA (guanine-N7-) methyltransferase (RNMT) in complex with sinefungin
PDB Code: 3EPP
Target Class: Transferases
Target: RNMT
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Sep 30 2008

Name: Human PR domain containing 12
PDB Code: 3EP0
Target Class: Transferases
Target: PRDM12
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Sep 30 2008

Name: Human SKI-like
PDB Code: 3EQ5
Target Class: Signalling proteins
Target: SKIL
Disease Area: cancer
Date Deposited: Sep 30 2008

[?]

Name: Human DNA (cytosine-5-)-methyltransferase 1
PDB Code: 3EPZ
Target Class: Transferases
Target: DNMT1
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Sep 30 2008

Name: Crystal structure of human acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in a ternary complex with products (AMP and Butyryl-CoA)
PDB Code: 3EQ6
Target Class: Miscellaneous
Target: LOC148158
Disease Area: metabolism, drug metabolism and toxicology
Date Deposited: Sep 30 2008

Name: Human G-protein subunit alpha (GNAI3) in complex with an engineered regulator of G-protein signaling type 2 domain
PDB Code: 2V4Z
Target Class: GTPases
Target: RGS2 + Galphai3
Disease Area: neurobiology
Date Deposited: Sep 30 2008

Name: Human 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)
PDB Code: 2V4W
Target Class: Miscellaneous
Target: HMGCS2
Disease Area:
Date Deposited: Sep 30 2008

Name: Human acyl-Coenzyme A binding domain containing 7
PDB Code: 3EPY
Target Class: Miscellaneous
Target: ACBD7
Disease Area:
Date Deposited: Sep 30 2008

Name: Human CTP synthetase 2 - glutaminase domain in complex with 5-OXO-L-NORLEUCINE
PDB Code: 2V4U
Target Class: Nucleotide metabolism
Target: CTPS2
Disease Area: cancer
Date Deposited: Sep 29 2008

[?]

Name: Plasmodium falciparum phosphoglycerate mutase
PDB Code: 3EOZ
Target Class: isomerasesTransferases
Target: PfPGM
Disease Area: parasitic disease
Date Deposited: Sep 29 2008

Name: Human neuroepithelial cell transforming gene 1 isoform 1
PDB Code: 3EO2
Target Class: G-Protein Regulators
Target: NET1
Disease Area: cancer, neurobiology
Date Deposited: Sep 26 2008

[?]

Name: Human Glutamine-Fructose-6-Phosphate Transaminase 1 (GFPT1)
PDB Code: 2V4M
Target Class: Amino oxidases
Target: GFPT1
Disease Area:
Date Deposited: Sep 26 2008

[?]

Name: Human glucosamine (UDP-N-acetyl)-2-epimerase-N-acetylmannosamine kinase
PDB Code: 3EO3
Target Class: Non-protein Kinase
Target: GNE
Disease Area: metabolism, cancer
Date Deposited: Sep 26 2008

[?]

Name: Toxoplasma gondii pyruvate kinase 55.m00007
PDB Code: 3EOE
Target Class: Non-protein Kinase
Target: 55.m00007
Disease Area: parasitic disease
Date Deposited: Sep 26 2008

Name: Human SPRY domain-containing SOCS box protein SSB-2 in complex with peptide
PDB Code: 3EMW
Target Class: SOCS-box-containing
Target: SPSB2
Disease Area:
Date Deposited: Sep 25 2008

Name: Human CTP:Phosphoethanolamine Cytidylyltransferase
PDB Code: 3ELB
Target Class: AA metabolic enzymes
Target: PCYT2
Disease Area: cancer
Date Deposited: Sep 22 2008

[?]

Name: Human phosphogluconate dehydrogenase
PDB Code: 2JKV
Target Class: Miscellaneous
Target: PGD
Disease Area:
Date Deposited: Aug 31 2008

[?]

Name: Human propionyl-CoA carboxylase (N-term, biotin acceptor domain)
PDB Code: 2JKU
Target Class: Miscellaneous
Target: PCCA
Disease Area:
Date Deposited: Aug 30 2008

Name: Human microtubule-associated protein 1 light chain 3 alpha isoform a [Homo sapiens]
PDB Code: 3ECI
Target Class: ubiquitin family
Target: MAP1LC3A
Disease Area:
Date Deposited: Aug 30 2008

[?]

Name: Human FLJ10324 (RADIL), RA domain
PDB Code: 3EC8
Target Class: Cell-type specific expression
Target: FLJ10324
Disease Area:
Date Deposited: Aug 29 2008

[?]

Name: Human hypothetical protein LOC27351
PDB Code: 3EBQ
Target Class: ubiquitin family
Target: PPPDE1
Disease Area:
Date Deposited: Aug 28 2008

[?]

Name: Human phospholipase A2-activating protein isoform 1 PUL domain in complex with P97 C-terminal peptide
PDB Code: 3EBB
Target Class: ubiquitin family
Target: PLAA
Disease Area: neurobiology
Date Deposited: Aug 27 2008

[?]

Name: Human Rho GTPase activating protein 11A, RhoGAP domain
PDB Code: 3EAP
Target Class: GTPases
Target: ARHGAP11A
Disease Area: signalling, neurobiology
Date Deposited: Aug 26 2008

[?]

Name: Cryptosporidium parvum cgd4 in complex with indirubin E804
PDB Code: 3EB0
Target Class: Malaria
Target: cgd4_240
Disease Area: parasitic disease
Date Deposited: Aug 26 2008

Name: Human hepatoma-derived growth factor-related protein 2, PWWP domain
PDB Code: 3EAE
Target Class: Miscellaneous
Target: HDGF2
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Aug 25 2008

Name: Human SPRY domain-containing SOCS box protein SSB-1
PDB Code: 2JK9
Target Class: SOCS-box-containing
Target: SPSB1
Disease Area: signalling
Date Deposited: Aug 22 2008

[?]

Name: Plasmodium falciparum ubiquitin conjugating enzyme Pf-UBC13 in complex with Pf-Uev1a
PDB Code: 3E95
Target Class: ubiquitin family
Target: Pf-UBC13
Disease Area: parasitic disease
Date Deposited: Aug 21 2008

Name: Human haspin in complex with a pyrazole-pyridazine ligand
PDB Code: 3E7V
Target Class: Protein Kinase
Target: GSG2 + K00522
Disease Area: chromatin and epigenetics
Date Deposited: Aug 19 2008

[?]

Name: Human phosphoserine aminotransferase in complex with PLP
PDB Code: 3E77
Target Class: AA metabolic enzymes
Target: SERC
Disease Area: cancer
Date Deposited: Aug 18 2008

Name: Human PTK9L protein tyrosine kinase 9-like (2nd ADF-H domain)
PDB Code: 2W0I
Target Class: Signalling proteins
Target: PTK9L (2nd ADF-H domain)
Disease Area: signalling
Date Deposited: Aug 18 2008

[?]

Name: Human damage-specific DNA binding protein 1
PDB Code: 3E0C
Target Class: Miscellaneous
Target: DDB1
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Jul 31 2008

Name: Toxoplasma gondii rhoptry kinase
PDB Code: 3DZO
Target Class: Malaria
Target: 33.m01398
Disease Area: parasitic disease
Date Deposited: Jul 30 2008

Name: Human ephrin receptor EphA3 in complex with inhibitor ALW-38.3
PDB Code: 3DZQ
Target Class: Protein Kinase
Target: EPHA3
Disease Area: cancer, signalling
Date Deposited: Jul 30 2008

Name: human chromosome 6 open reading frame 197 [Homo sapiens]
PDB Code: 3DZX
Target Class: G-Protein Regulators
Target: TBC1D22B
Disease Area:
Date Deposited: Jul 30 2008

[?]

Name: Tax1 (human T-cell leukemia virus type I) binding protein 3
PDB Code: 2VZ5
Target Class: Linkers
Target: TAX1BP3
Disease Area: signalling
Date Deposited: Jul 30 2008

Name: Human fumarate hydratase precursor
PDB Code: 3E04
Target Class: Miscellaneous
Target: FH
Disease Area:
Date Deposited: Jul 30 2008

Name: Human calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha
PDB Code: 2VZ6
Target Class: Protein Kinase
Target: CAMK2A
Disease Area: signalling, neurobiology
Date Deposited: Jul 30 2008

Name: Human xenobiotic/medium-chain fatty acid:CoA ligase (L64P mutation) in complex with AMP
PDB Code: 2VZE
Target Class: Miscellaneous
Target: LOC148158 (L64P) + AMP
Disease Area: metabolism, drug metabolism and toxicology
Date Deposited: Jul 30 2008

Name: Human RAB3B, member RAS oncogene family
PDB Code: 3DZ8
Target Class: GTPases
Target: RAB3B
Disease Area: cancer, signalling
Date Deposited: Jul 29 2008

[?]

Name: Human tyrosine aminotransferase
PDB Code: 3DYD
Target Class: AA metabolic enzymes
Target: TAT
Disease Area:
Date Deposited: Jul 27 2008

[?]

Name: Toxoplasma gondii calcium dependent protein kinase 541.m00134, kinase domain
PDB Code: 3DXN
Target Class: Malaria
Target: 541.m00134
Disease Area: parasitic disease
Date Deposited: Jul 24 2008

Name: Human CREB binding protein (bromodomain)
PDB Code: 3DWY
Target Class: Bromodomain
Target: CREBBP (bromodomain)
Disease Area:
Date Deposited: Jul 23 2008

[?]

Name: Human ADP-ribosylation factor GTPase activating protein 1
PDB Code: 3DWD
Target Class: G-Protein Regulators
Target: ARFGAP1
Disease Area: cancer, neurobiology
Date Deposited: Jul 22 2008

[?]

Name: Human guanine monophosphate synthetase
PDB Code: 2VXO
Target Class: Nucleotide metabolism
Target: GMPS
Disease Area: cancer
Date Deposited: Jul 08 2008

[?]

Name: Human chromobox homolog 3 in complex with a tri-methylated lysine peptide
PDB Code: 3DM1
Target Class: Methyl-lysine readers
Target: CBX3
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Jun 30 2008

[?]

Name: Human enoyl Coenzyme A hydratase domain containing 3
PDB Code: 2VX2
Target Class: Miscellaneous
Target: ECHDC3
Disease Area:
Date Deposited: Jun 30 2008

Name: Human 3-oxoacid CoA transferase
PDB Code: 3DLX
Target Class: Miscellaneous
Target: OXCT
Disease Area:
Date Deposited: Jun 30 2008

Name: Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A in complex with K00611a
PDB Code: 2VX3
Target Class: Protein Kinase
Target: DYRK1A + K00611a
Disease Area: signalling, neurobiology
Date Deposited: Jun 30 2008

[?]

Name: Human haspin in complex with AMP
PDB Code: 3DLZ
Target Class: Protein Kinase
Target: GSG2 + AMP
Disease Area: chromatin and epigenetics, signalling
Date Deposited: Jun 30 2008

[?]

Name: Human PDZ domain containing ring finger 1 (2nd PDZ domain)
PDB Code: 2VWR
Target Class: Linkers
Target: LNX2 (2nd PDZ domain)
Disease Area: neurobiology
Date Deposited: Jun 28 2008

Name: Human histone-lysine N-2 methyltransferase (SET domain bifurcated 1), Tudor domain
PDB Code: 3DLM
Target Class: Transferases
Target: SETDB1
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Jun 27 2008

Name: Human carnosine dipeptidase 1
PDB Code: 3DLJ
Target Class: Proteases
Target: CNDP1
Disease Area:
Date Deposited: Jun 27 2008

Name: Human ubiquitin-conjugating enzyme E2-like, LDH domain
PDB Code: 3DL2
Target Class: ubiquitin family
Target: UEV3
Disease Area: signalling
Date Deposited: Jun 26 2008

Name: Human CYP2R1 in complex with 1-alpha-hydroxy-vitamin D2
PDB Code: 3DL9
Target Class: Miscellaneous
Target: CYP2R1
Disease Area: metabolism
Date Deposited: Jun 26 2008

Name: Human DEAD-box RNA-helicase DDX52, conserved domain I in complex with ADP
PDB Code: 3DKP
Target Class: ATPases
Target: DDX52
Disease Area: cancer
Date Deposited: Jun 25 2008

[?]

Name: Human HECTD1 CPH Domain
PDB Code: 3DKM
Target Class: ubiquitin family
Target: HECTD1
Disease Area: signalling
Date Deposited: Jun 25 2008

[?]

Name: Human ephrin type-A receptor 7 kinase domain in complex with inhibitor ALW-II-49-7
PDB Code: 3DKO
Target Class: Protein Kinase
Target: EPHA7
Disease Area: cancer, signalling
Date Deposited: Jun 25 2008

[?]

Name: Human tRNA-specific adenosine-34 deaminase subunit ADAT2
PDB Code: 3DH1
Target Class: Nucleotide metabolism
Target: DEADC1
Disease Area:
Date Deposited: Jun 17 2008

[?]

Name: Cryptosporidium parvum calcium dependent protein kinase 1, protein kinase domain
PDB Code: 3DFA
Target Class: Malaria
Target: Cp-CDPK1-Pk
Disease Area: parasitic disease
Date Deposited: Jun 11 2008

Name: Human Ribonucleotide reductase, subunit M2 B
PDB Code: 2VUX
Target Class: Nucleotide metabolism
Target: RRM2B
Disease Area: metabolism, cancer
Date Deposited: May 31 2008

[?]

Name: Human Lethal(3)malignant brain tumor-like 2 protein in complex with H4K20me
PDB Code: 3DBB
Target Class: Methyl-lysine readers
Target: L3MBTL2
Disease Area: cancer, chromatin and epigenetics
Date Deposited: May 31 2008

Name: Human cytochrome P450, family 7, subfamily A, polypeptide 1
PDB Code: 3DAX
Target Class: Miscellaneous
Target: CYP7A1
Disease Area: metabolism
Date Deposited: May 30 2008

Name: Human haspin in complex with 5-Iodotubercidin
PDB Code: 2VUW
Target Class: Protein Kinase
Target: GSG2 + K00224
Disease Area: chromatin and epigenetics, signalling
Date Deposited: May 30 2008

[?]

Name: Human xenobiotic/medium-chain fatty acid:CoA ligase in complex with AMP-CPP
PDB Code: 3DAY
Target Class: Miscellaneous
Target: LOC148158 + AMP-CPP
Disease Area: metabolism, drug metabolism and toxicology
Date Deposited: May 30 2008

Name: Human two AAA domain containing protein
PDB Code: 3DAI
Target Class: Bromodomain
Target: ATAD2
Disease Area: chromatin and epigenetics, signalling
Date Deposited: May 29 2008

[?]

Name: Human UHRF1, tandem tudor domain
PDB Code: 3DB4
Target Class: Miscellaneous
Target: UHRF1
Disease Area: cancer, chromatin and epigenetics, signalling
Date Deposited: May 29 2008

[?]

Name: Human UHRF1, tandem tudor domain, in complex with H3K9 peptide
PDB Code: 3DB3
Target Class: Miscellaneous
Target: UHRF1
Disease Area: cancer, chromatin and epigenetics, signalling
Date Deposited: May 29 2008

[?]

Name: Human PR domain-containing protein 1 methyltransferase domain
PDB Code: 3DAL
Target Class: Transferases
Target: PRDM1
Disease Area: cancer
Date Deposited: May 29 2008

Name: Human PR domain-containing protein 4 methyltransferase domain
PDB Code: 3DB5
Target Class: Transferases
Target: PRDM4
Disease Area: cancer
Date Deposited: May 29 2008

Name: Human carbonic anhydrase XIII
PDB Code: 3DA2
Target Class: Miscellaneous
Target: CA13
Disease Area: metabolism, signalling
Date Deposited: May 28 2008

[?]

Name: Human Fidgetin-like 1
PDB Code: 3D8B
Target Class: ATPases
Target: FIGNL1
Disease Area:
Date Deposited: May 23 2008

[?]

Name: Cryptosporidium parvum phosphoglycerate mutase
PDB Code: 3D8H
Target Class: isomerasesTransferases
Target: Cp-PGM
Disease Area: parasitic disease
Date Deposited: May 23 2008

Name: Human GCN5 general control of amino-acid synthesis 5-like 2
PDB Code: 3D7C
Target Class: Bromodomain
Target: GCN5L2
Disease Area:
Date Deposited: May 21 2008

[?]

Name: Human arachidonate 12-lipoxygenase
PDB Code: 3D3L
Target Class: Miscellaneous
Target: ALOX12
Disease Area: cancer
Date Deposited: May 12 2008

Name: Human PDZ domain containing 1 (4th PDZ domain)
PDB Code: 2VSP
Target Class: Linkers
Target: PDZK1
Disease Area: metabolism, signalling
Date Deposited: Apr 30 2008

Name: Human dual specificity phosphatase 16
PDB Code: 2VSW
Target Class: Phosphatases
Target: DUSP16
Disease Area: signalling
Date Deposited: Apr 30 2008

[?]

Name: Human ephrin receptor EPHA2 in complex with ephrin A1 isoform a precursor
PDB Code: 3CZU
Target Class: Protein Kinase
Target: EPHA2-EFNA1 complex
Disease Area: cancer, signalling
Date Deposited: Apr 30 2008

[?]

Name: Human rhophilin-like protein (PDZ domain)
PDB Code: 2VSV
Target Class: Linkers
Target: RHPN2
Disease Area:
Date Deposited: Apr 29 2008

Name: Human cytochrome P450, family 2, R1 in complex with vitamin D2
PDB Code: 3CZH
Target Class: Miscellaneous
Target: CYP2R1
Disease Area: metabolism
Date Deposited: Apr 29 2008

Name: Human glutaminase
PDB Code: 3CZD
Target Class: AA metabolic enzymes
Target: GLS
Disease Area: cancer
Date Deposited: Apr 29 2008

[?]

Name: Human PIM1 in complex with a consensus peptide and a Beta Carboline Ligand (CARB-10)
PDB Code: 3CXW
Target Class: Protein Kinase
Target: PIM1+ peptide + CARB-10
Disease Area: chromatin and epigenetics, signalling
Date Deposited: Apr 25 2008

Name: Human PIM1 in complex with a consensus peptide and a Beta Carboline Ligand (CARB-13)
PDB Code: 3CY2
Target Class: Protein Kinase
Target: PIM1 + peptide + CARB-13
Disease Area: chromatin and epigenetics, signalling
Date Deposited: Apr 25 2008

Name: Human PIM1 in complex with a consensus peptide and the JNK Inhibitor V
PDB Code: 3CY3
Target Class: Protein Kinase
Target: PIM1 + peptide + JNK Inhibitor V
Disease Area: chromatin and epigenetics, signalling
Date Deposited: Apr 25 2008

Name: Human glutathione peroxidase 8
PDB Code: 3CYN
Target Class: Oxidoreductases
Target: LOC493869 (GPX8)
Disease Area:
Date Deposited: Apr 25 2008

[?]

Name: Plasmodium falciparum thioredoxin
PDB Code: 3CXG
Target Class: Oxidoreductases
Target: PfTrx
Disease Area: parasitic disease
Date Deposited: Apr 24 2008

Name: Human chimerin 1
PDB Code: 3CXL
Target Class: G-Protein Regulators
Target: CHN1
Disease Area: neurobiology
Date Deposited: Apr 24 2008

[?]

Name: Human nuclear receptor subfamily 1, group D, member 2 in complex with heme
PDB Code: 3CQV
Target Class: Miscellaneous
Target: NR1D2
Disease Area: metabolism, cancer, drug metabolism and toxicology
Date Deposited: Apr 03 2008

[?]

Name: Cp-GAPDH+NAD: Cryptosporidium parvum glyceraldehyde-3-phosphate dehydrogenase (cgd6_3790) in complex with NAD
PDB Code: 3CPS
Target Class: Oxidoreductases
Target: Cp-GAPDH+NAD
Disease Area: parasitic disease
Date Deposited: Apr 01 2008

Name: Human eukaryotic translation initiation factor 5A
PDB Code: 3CPF
Target Class: G-Protein Regulators
Target: EIF5A
Disease Area: cancer
Date Deposited: Mar 31 2008

[?]

Name: Human basic beta 2 syntrophin
PDB Code: 2VRF
Target Class: Linkers
Target: SNTB2
Disease Area:
Date Deposited: Mar 31 2008

Name: Human peroxisomal delta3,5, delta2,4-dienoyl CoA isomerase
PDB Code: 2VRE
Target Class: Miscellaneous
Target: ECH1
Disease Area:
Date Deposited: Mar 31 2008

[?]

Name: Human class II alcohol dehydrogenase in complex with NAD and Zn
PDB Code: 3COS
Target Class: Oxidoreductases
Target: ADH4
Disease Area:
Date Deposited: Mar 31 2008

[?]

Name: Human farnesyl diphosphate synthase in complex with NE58025
PDB Code: 3CP6
Target Class: Miscellaneous
Target: FDPS + NE58025
Disease Area: metabolism, signalling
Date Deposited: Mar 31 2008

[?]

Name: Human Protein Receptor Tyrosine Phosphatase E
PDB Code: 2JJD
Target Class: Phosphatases
Target: PTPRE
Disease Area: metabolism, signalling, neurobiology
Date Deposited: Mar 31 2008

[?]

Name: Human Nudix motif 16 (NUDT16)
PDB Code: 3COU
Target Class: Nucleotide metabolism
Target: NUDT16
Disease Area: cancer
Date Deposited: Mar 29 2008

[?]

Name: Human Cystathionine Gamma-Lyase in complex with DL-propargylglycine
PDB Code: 3COG
Target Class: AA metabolic enzymes
Target: CTH
Disease Area: metabolism, neurobiology
Date Deposited: Mar 28 2008

Name: Human neuroblastoma RAS viral (v-ras) oncogene homolog in complex with GDP
PDB Code: 3CON
Target Class: GTPases
Target: NRAS
Disease Area: cancer, signalling
Date Deposited: Mar 28 2008

[?]

Name: Human chromobox homolog 4 [Homo sapiens]
PDB Code: 2K28
Target Class: Methyl-lysine readers
Target: CBX4
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Mar 27 2008

[?]

Name: Human Dihydropyrimidinase
PDB Code: 2VR2
Target Class: Oxidoreductases
Target: DHP
Disease Area: drug metabolism and toxicology
Date Deposited: Mar 25 2008

[?]

Name: Plasmodium falciparum Rab5a protein (PFB0500c) in complex with GDP
PDB Code: 3CLV
Target Class: GTPases
Target: Pf-RAB5A
Disease Area: parasitic disease
Date Deposited: Mar 20 2008

Name: Human Set and Ring associated (SRA) domain of UHRF1 bound to methylated DNA
PDB Code: 3CLZ
Target Class: ubiquitin family
Target: UHRF1
Disease Area: cancer, chromatin and epigenetics, signalling
Date Deposited: Mar 20 2008

[?]

Name: Human cytosolic sulfotransferase, sub-family 1B, cember 1 in complex with PAP and Resveratrol
PDB Code: 3CKL
Target Class: Transferases
Target: SULT1B1
Disease Area: metabolism, cancer, drug metabolism and toxicology
Date Deposited: Mar 16 2008

[?]

Name: Human methyltransferase like 1 in complex with SAM
PDB Code: 3CKK
Target Class: Transferases
Target: METTL1
Disease Area: metabolism
Date Deposited: Mar 16 2008

[?]

Name: Human baculoviral IAP repeat-containing 6, Ubiquitin-conjugating domain
PDB Code: 3CEG
Target Class: Apoptosisubiquitin family
Target: BIRC6
Disease Area: cancer, signalling
Date Deposited: Feb 29 2008

[?]

Name: Human guanine monophosphate synthetase - glutaminase domain
PDB Code: 2VPI
Target Class: Nucleotide metabolism
Target: GMPS
Disease Area: cancer
Date Deposited: Feb 29 2008

[?]

Name: Human TTK protein kinase
PDB Code: 3CEK
Target Class: Protein Kinase
Target: TTK
Disease Area: signalling
Date Deposited: Feb 29 2008

[?]

Name: PDZ domain of human protein tyrosine phosphatase, non-receptor type 4
PDB Code: 2VPH
Target Class: Linkers
Target: PTPN4
Disease Area: signalling, neurobiology
Date Deposited: Feb 29 2008

Name: Human kelch-like 12
PDB Code: 2VPJ
Target Class: BTB-Kelch
Target: KLHL12
Disease Area: signalling
Date Deposited: Feb 29 2008

[?]

Name: Human myoneurin
PDB Code: 2VPK
Target Class: BTB-Kelch
Target: MYNN
Disease Area: signalling, neurobiology
Date Deposited: Feb 29 2008

Name: Human Lethal(3)malignant brain tumor-like 2 protein
PDB Code: 3CEY
Target Class: Methyl-lysine readers
Target: L3MBTL2
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Feb 29 2008

Name: Human kinesin light chain 2 TPR domain
PDB Code: 3CEQ
Target Class: Miscellaneous
Target: KLC2
Disease Area: neurobiology
Date Deposited: Feb 29 2008

Name: Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor PJ34
PDB Code: 3CE0
Target Class: Poly ADP-ribose polymerase
Target: PARP3
Disease Area: cancer
Date Deposited: Feb 28 2008

[?]

Name: Toxoplasma gondii specific mitochondrial acyl carrier protein
PDB Code: 3CE7
Target Class: Lipid signalling
Target: Tg-mACP
Disease Area: parasitic disease
Date Deposited: Feb 28 2008

Name: Human feline sarcoma oncogene (active) in complex with Staurosporine and a Consensus Peptide
PDB Code: 3CD3
Target Class: Protein Kinase
Target: FES + staurosporin + peptide
Disease Area: signalling
Date Deposited: Feb 26 2008

structure gallery

1128 structures