Structure Gallery

Name: Human Aurora B Kinase in complex with INCENP and VX-680
PDB Code: 4AF3
Target Class: MiscellaneousProtein Kinase
Target: XX07AURKB
Disease Area:
Date Deposited: 2012-01-16

Name: Crystal structure of human LACTB2
PDB Code: 4AD9
Target Class: Miscellaneous
Target: LACTB2
Disease Area: cancer, metabolism
Date Deposited: 2011-12-22

Name: Full length Mouse STRAP (TTC5)
PDB Code: 4ABN
Target Class: Miscellaneous
Target: TTC5MMA
Disease Area:
Date Deposited: 2011-12-09

Name: JMJD5 domain of human Lysine-specific demethylase 8 (KDM8) in complex with N-oxalylglycine (NOG)
PDB Code: 4AAP
Target Class: Oxidoreductases
Target: FLJ13798
Disease Area:
Date Deposited: 2011-12-05

Name: Human P63 Tetramerization 2 domain
PDB Code: 4A9Z
Target Class: Miscellaneous
Target: TP73L
Disease Area: cancer, signalling, neurobiology
Date Deposited: 2011-11-30

Name: Catalytic domain of the heterodimeric human soluble guanylate cyclase 1
PDB Code: 3UVJ
Target Class: Nucleotide metabolismSignalling proteins
Target: XX13GUCY1A3
Disease Area:
Date Deposited: 2011-11-30

Name: Human CDKL2 kinase domain
PDB Code: 4AAA
Target Class: Protein Kinase
Target: CDKL2
Disease Area:
Date Deposited: 2011-11-30

Name: Human Mitochondrial ABC Transporter, ABCB10 (plate form)
PDB Code: 4AA3
Target Class: Membrane proteins
Target: ABCB10
Disease Area:
Date Deposited: 2011-11-30

Name: Bromodomain of human nucleosome-remodeling factor subunit BPTF
PDB Code: 3UV2
Target Class: Bromodomain
Target: FALZ
Disease Area:
Date Deposited: 2011-11-29

Name: Second bromodomain of human Transcription initiation factor TFIID subunit 1 (TAF1)
PDB Code: 3UV4
Target Class: Bromodomain
Target: TAF1
Disease Area: cancer, signalling
Date Deposited: 2011-11-29

Name: tandem bromodomains of human Transcription initiation factor TFIID subunit 1 (TAF1)
PDB Code: 3UV5
Target Class: Bromodomain
Target: TAF1
Disease Area: cancer, signalling
Date Deposited: 2011-11-29

Name: Bromodomain of human Transcription activator BRG1 (SMARCA4) in complex with N-Methyl-2-pyrrolidone
PDB Code: 3UVD
Target Class: Bromodomain
Target: SMARCA4
Disease Area:
Date Deposited: 2011-11-29

Name: Human l(3)mbt-like 3, 3 MBT repeats
PDB Code: 3UT1
Target Class: Methyl-lysine readers
Target: L3MBTL3
Disease Area: chromatin and epigenetics
Date Deposited: 2011-11-24

Name: Human WD repeat domain 5 in complex with methyl 3-((3-methoxy-phenyl)-formylamino)-4-(4-methyl-piperazin-1-yl)-benzoate
PDB Code: 3UR4
Target Class: Miscellaneous
Target: WDR5
Disease Area: cancer, chromatin and epigenetics
Date Deposited: 2011-11-21

Name: Plasmodium falciparum guanine monophosphate synthetase (PF10_0123), in complex with GMP
PDB Code: 3UOW
Target Class: Transferases
Target: PfGMPS
Disease Area: parasitic disease
Date Deposited: 2011-11-17

Name: Human lamin B2, C-terminal IF-tail domain
PDB Code: 2LLL
Target Class: Miscellaneous
Target: LMNB2
Disease Area: signalling
Date Deposited: 2011-11-11

Name: Human cyclin D binding myb-like transcription factor 1, N-terminal myb-like 1 domain
PDB Code: 2LLK
Target Class: Miscellaneous
Target: DMTF1
Disease Area: signalling
Date Deposited: 2011-11-10

Name: Crystal Structure of human FABP9
PDB Code: 4A60
Target Class: Lipid signalling
Target: FABP9
Disease Area:
Date Deposited: 2011-10-31

Name: Crystal structure of the N-terminal domain of human Cul4B at 2.57Å resolution
PDB Code: 4A64
Target Class: Miscellaneous
Target: CUL4B
Disease Area:
Date Deposited: 2011-10-31

Name: Human p73-ASPP2 complex at 2.6 Å resolution
PDB Code: 4A63
Target Class: Miscellaneous
Target: XX01TP73
Disease Area:
Date Deposited: 2011-10-31

Name: First bromodomain of human BRD4 in complex with Alprazolam
PDB Code: 3U5J
Target Class: Bromodomain
Target: BRD4
Disease Area: cancer, chromatin and epigenetics, signalling
Date Deposited: 2011-10-11

Name: First bromodomain of human BRD4 in complex with Midazolam
PDB Code: 3U5K
Target Class: Bromodomain
Target: BRD4
Disease Area: cancer, chromatin and epigenetics, signalling
Date Deposited: 2011-10-11

Name: First bromodomain of human BRD4 in complex with a benzo-triazepine ligand (BzT-7)
PDB Code: 3U5L
Target Class: Bromodomain
Target: BRD4
Disease Area: cancer, chromatin and epigenetics, signalling
Date Deposited: 2011-10-11

Name: Human Glycogenin-1 (GYG1) complexed with manganese and glucose or a glucal species
PDB Code: 3U2W
Target Class: Miscellaneous
Target: GYG1
Disease Area:
Date Deposited: 2011-10-04

Name: Human Glycogenin-1 (GYG1) complexed with manganese, UDP and maltotetraose
PDB Code: 3U2U
Target Class: Miscellaneous
Target: GYG1
Disease Area:
Date Deposited: 2011-10-04

Name: Human Glycogenin-1 (GYG1) complexed with manganese, UDP and 1-deoxyglucose
PDB Code: 3U2X
Target Class: Miscellaneous
Target: GYG1
Disease Area:
Date Deposited: 2011-10-04

Name: Human Glycogenin-1 (GYG1) complexed with manganese
PDB Code: 3U2T
Target Class: Miscellaneous
Target: GYG1
Disease Area:
Date Deposited: 2011-10-04

Name: Human pyruvate kinase M2 in complex with activator
PDB Code: 3U2Z
Target Class: Non-protein Kinase
Target: PKM2
Disease Area: cancer
Date Deposited: 2011-10-04

Name: Human Glycogenin-1 (GYG1) complexed with manganese, UDP and maltohexaose
PDB Code: 3U2V
Target Class: Miscellaneous
Target: GYG1
Disease Area:
Date Deposited: 2011-10-04

Name: BAR domain of human Amphiphysin, isoform 1
PDB Code: 4A3A
Target Class: Miscellaneous
Target: AMPH
Disease Area:
Date Deposited: 2011-09-30

Name: Human RNA polymerase-associated protein RTF1 homolog, Plus-3 domain
PDB Code: 3U1U
Target Class: Methyl-lysine readers
Target: RTF1
Disease Area: chromatin and epigenetics
Date Deposited: 2011-09-30

Name: 2nd SH3 domain from Human CD2AP in complex with a proline-rich peptide from human RIN3
PDB Code: 3U23
Target Class: Miscellaneous
Target: CD2AP
Disease Area:
Date Deposited: 2011-09-30

Name: Human ubiquitin specific peptidase 37, pleckstrin homology domain
PDB Code: 3U12
Target Class: Ubiquitylation
Target: USP37
Disease Area: signalling
Date Deposited: 2011-09-29

Name: Human vesicle amine transporter VAT-1 homolog-like protein
PDB Code: 4A27
Target Class: Oxidoreductases
Target: KIAA1576
Disease Area:
Date Deposited: 2011-09-22

Name: Human mitochondrial endo-exonuclease
PDB Code: 4A1N
Target Class: Miscellaneous
Target: ENDOGL1
Disease Area: metabolism
Date Deposited: 2011-09-16

Name: Human itchy E3 ubiquitin protein ligase homolog, HECT domain
PDB Code: 3TUG
Target Class: Ubiquitylation
Target: ITCH
Disease Area: cancer
Date Deposited: 2011-09-16

Name: Crystal Structure of the Kinase Domain of ROR2
PDB Code: 3ZZW
Target Class: Protein Kinase
Target: ROR2
Disease Area: signalling
Date Deposited: 2011-09-05

Name: Human serine threonine kinase-10 bound to bosutinib
PDB Code: 3ZZ2
Target Class: Protein Kinase
Target: STK10
Disease Area: cancer, signalling
Date Deposited: 2011-08-31

Name: Human poly-bromodomain containing protein 1, fourth bromodomain
PDB Code: 3TLP
Target Class: Bromodomain
Target: PB1
Disease Area: cancer, chromatin and epigenetics, signalling
Date Deposited: 2011-08-30

Name: Plasmodium falciparum adenylate kinase (PF10_0086), in complex with ADP and ATP
PDB Code: 3TLX
Target Class: Non-protein Kinase
Target: Pf-AK
Disease Area: parasitic disease
Date Deposited: 2011-08-30

Name: Human glutaredoxin 3, first glutaredoxin domain
PDB Code: 3ZYW
Target Class: Oxidoreductases
Target: TXNL2
Disease Area: cancer, signalling
Date Deposited: 2011-08-29

Name: Human tandem VHS and FYVE domains of Hepatocyte growth factor-regulated tyrosine kinase substrate
PDB Code: 3ZYQ
Target Class: Miscellaneous
Target: HGS
Disease Area:
Date Deposited: 2011-08-24

Name: Human FYVE domain of endofin
PDB Code: 3T7L
Target Class: Miscellaneous
Target: ZFYVE16
Disease Area:
Date Deposited: 2011-07-30

Name: Human Glycogenin-1 in complex with manganese and UDP, in a triclinic closed form
PDB Code: 3T7M
Target Class: Miscellaneous
Target: GYG1
Disease Area:
Date Deposited: 2011-07-30

Name: Human Glycogenin-1 in complex with manganese and UDP, in a monoclinic closed form
PDB Code: 3T7N
Target Class: Miscellaneous
Target: GYG1
Disease Area:
Date Deposited: 2011-07-30

Name: Human Glycogenin-1 in complex with manganese, UDP-Glucose and glucose
PDB Code: 3T7O
Target Class: Miscellaneous
Target: GYG1
Disease Area:
Date Deposited: 2011-07-30

Name: Human glyoxalase domain-containing protein 5
PDB Code: 3ZW5
Target Class: Oxidoreductases
Target: GLOD5
Disease Area:
Date Deposited: 2011-07-28

Name: Human tRNase Z, short form
PDB Code: 3ZWF
Target Class: Miscellaneous
Target: ELAC1
Disease Area: cancer
Date Deposited: 2011-07-28

Name: Human DOT1-like histone H3 methyltransferase, in complex with Bromo-deaza-SAH
PDB Code: 3SX0
Target Class: Transferases
Target: DOT1L
Disease Area: cancer, chromatin and epigenetics
Date Deposited: 2011-07-15

Name: First bromodomain of human BRD4 in complex with a dihydro-quinazolin ligand
PDB Code: 3SVF
Target Class: Bromodomain
Target: BRD4
Disease Area: cancer, chromatin and epigenetics, signalling
Date Deposited: 2011-07-12

Name: First bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand
PDB Code: 3SVG
Target Class: Bromodomain
Target: BRD4
Disease Area: cancer, chromatin and epigenetics, signalling
Date Deposited: 2011-07-12

Name: Human CREB binding protein (bromodomain) in complex with a 3,5-dimethylisoxazol ligand
PDB Code: 3SVH
Target Class: Bromodomain
Target: CREBBP
Disease Area: cancer, metabolism, chromatin and epigenetics, signalling, neurobiology
Date Deposited: 2011-07-12

Name: Human activin receptor type-IIA (ACVR2A) kinase domain in complex with a quinazolin
PDB Code: 3SOC
Target Class: Protein Kinase
Target: ACVR2
Disease Area: cancer
Date Deposited: 2011-06-30

Name: 3rd PDZ domain of the human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (MAGI3)
PDB Code: 3SOE
Target Class: PDZ linkers
Target: MAGI3
Disease Area: cancer
Date Deposited: 2011-06-30

Name: BAR domain of human amphiphysin, isoform 1 .
PDB Code: 3SOG
Target Class: Miscellaneous
Target: AMPH
Disease Area:
Date Deposited: 2011-06-30

Name: Human methylmalonyl aciduria type C with homocystinuria
PDB Code: 3SOM
Target Class: Miscellaneous
Target: MMACHC
Disease Area:
Date Deposited: 2011-06-30

Name: Human ankyrin repeat, family A (RFXANK-like), 2
PDB Code: 3SO8
Target Class: Miscellaneous
Target: ANKRA2
Disease Area: signalling
Date Deposited: 2011-06-29

Name: Human HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2, N-terminal domain
PDB Code: 2LFE
Target Class: Ubiquitylation
Target: HECW2
Disease Area: cancer
Date Deposited: 2011-06-29

Name: Human Poly (ADP-ribose) polymerase family, member 14 in complex with a quinazoline inhibitor
PDB Code: 3SMI
Target Class: Poly ADP-ribose polymerase
Target: PARP14
Disease Area: cancer
Date Deposited: 2011-06-28

Name: Human Poly (ADP-ribose) polymerase family, member 14 in complex with a pyrimidine-like inhibitor
PDB Code: 3SMJ
Target Class: Poly ADP-ribose polymerase
Target: PARP14
Disease Area: cancer
Date Deposited: 2011-06-28

Name: Human cytochrome P450, family 7, subfamily A, polypeptide 1, in complex with cholest-4-en-3-one
PDB Code: 3SN5
Target Class: Miscellaneous
Target: CYP7A1
Disease Area: metabolism
Date Deposited: 2011-06-28

Name: Human pantothenate kinase 3 in complex with a pantothenate analog
PDB Code: 3SMS
Target Class: Non-protein Kinase
Target: PANK3
Disease Area: metabolism
Date Deposited: 2011-06-28

Name: Human pantothenate kinase 1 in complex with acetyl-coA (monoclinic crystal)
PDB Code: 3SMP
Target Class: Non-protein Kinase
Target: PANK1
Disease Area: metabolism
Date Deposited: 2011-06-28

Name: Human SET domain containing 3 in complex with S-adenosyl-methionine
PDB Code: 3SMT
Target Class: Transferases
Target: SETD3
Disease Area: chromatin and epigenetics
Date Deposited: 2011-06-28

Name: Human eukaryotic translation initiation factor 4E, in complex with a 4EBP1 peptide complex, without cap
PDB Code: 3SMU
Target Class: G-Protein Regulators
Target: EIF4E
Disease Area: cancer
Date Deposited: 2011-06-28

Name: Human WD repeat domain 5 in complex with 2-chloro-N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]benzamide
PDB Code: 3SMR
Target Class: Miscellaneous
Target: WDR5
Disease Area: chromatin and epigenetics
Date Deposited: 2011-06-28

Name: Human protein arginine methyltransferase 3 in complex with 1-(1,2,3-benzothiadiazol-6-yl)-3-[2-(cyclohexen-1-yl)ethyl]urea
PDB Code: 3SMQ
Target Class: Transferases
Target: PRMT3
Disease Area: chromatin and epigenetics
Date Deposited: 2011-06-28

Name: Human Poly (ADP-ribose) polymerase family, member 14 in complex with 6(5H)-phenanthridinone
PDB Code: 3SE2
Target Class: Poly ADP-ribose polymerase
Target: PARP14
Disease Area: cancer
Date Deposited: 2011-06-27

Name: Human metabotropic glutamate receptor 3, extracellular ligand binding domain, in complex with antagonist LY341495
PDB Code: 3SM9
Target Class: Membrane proteins
Target: GRM3
Disease Area: neurobiology
Date Deposited: 2011-06-27

Name: Human LIMK1 kinase domain in complex with staurosporine
PDB Code: 3S95
Target Class: Phosphoinosotide dependent signalling
Target: LIMK1
Disease Area: cancer
Date Deposited: 2011-05-31

Name: Human BRD3, first bromodomain in complex with the inhibitor JQ1
PDB Code: 3S91
Target Class: Bromodomain
Target: BRD3
Disease Area: cancer, signalling
Date Deposited: 2011-05-31

Name: Human BRD3, second bromodomain in complex with the inhibitor JQ1
PDB Code: 3S92
Target Class: Bromodomain
Target: BRD3
Disease Area: cancer, signalling
Date Deposited: 2011-05-31

Name: Human acetyl-CoA carboxylase 1, biotin carboxylase
PDB Code: 2YL2
Target Class: Miscellaneous
Target: ACACA
Disease Area: cancer
Date Deposited: 2011-05-31

Name: Human mitochondrial ABC transporter, ABCB10
PDB Code: 2YL4
Target Class: Membrane proteins
Target: ABCB10
Disease Area:
Date Deposited: 2011-05-31

Name: Human tudor domain containing 5, conserved motif
PDB Code: 3S93
Target Class: Methyl-lysine readers
Target: TDRD5
Disease Area: chromatin and epigenetics
Date Deposited: 2011-05-31

Name: Human mitochondrial enolase superfamily member 1
PDB Code: 4A35
Target Class: Miscellaneous
Target: ENOSF1
Disease Area:
Date Deposited: 2011-05-31

Name: Human SET domain containing 1A, RRM domain
PDB Code: 3S8S
Target Class: Transferases
Target: SETD1A
Disease Area: chromatin and epigenetics
Date Deposited: 2011-05-30

Name: Human suppressor of variegation 4-20 homolog 1, SET domain, in complex with S-adenosyl-L methionine
PDB Code: 3S8P
Target Class: Transferases
Target: SUV420H1
Disease Area: chromatin and epigenetics
Date Deposited: 2011-05-30

Name: Human DNA-damage inducible 1 homolog 1, retroviral-like protease (rvp) domain
PDB Code: 3S8I
Target Class: Ubiquitylation
Target: DDI1
Disease Area: signalling
Date Deposited: 2011-05-28

Name: Plasmodium falciparum methionine aminopeptidase 1b (PF10_0150)
PDB Code: 3S6B
Target Class: Proteases
Target: PfMetAP1b
Disease Area: parasitic disease
Date Deposited: 2011-05-25

Name: Human thiamin pyrophosphokinase 1
PDB Code: 3S4Y
Target Class: Non-protein Kinase
Target: TPK1
Disease Area: metabolism
Date Deposited: 2011-05-20

Name: Rabbit ryanodine receptor 1 (skeletal), RYR domain
PDB Code: 3RQR
Target Class: Proteases
Target: RYR1
Disease Area: metabolism
Date Deposited: 2011-04-28

Name: Human complement component 1, q subcomponent binding protein
PDB Code: 3RPX
Target Class: Miscellaneous
Target: C1QBP
Disease Area: cancer, metabolism
Date Deposited: 2011-04-27

Name: Human suppressor of variegation 4-20 homolog 2, methyltransferase domain, in complex with S-adenosyl-L-methionine
PDB Code: 3RQ4
Target Class: Transferases
Target: SUV420H2
Disease Area: chromatin and epigenetics
Date Deposited: 2011-04-27

Name: Toxoplasma gondii mitogen-activated protein kinase (25.m01780)
PDB Code: 3RP9
Target Class: Protein Kinase
Target: MAPK
Disease Area: parasitic disease
Date Deposited: 2011-04-26

Name: Human baiap2a BAI1-associated protein 2a
PDB Code: 3RNJ
Target Class: Miscellaneous
Target: BAIAP2
Disease Area:
Date Deposited: 2011-04-22

Name: Human malonyl CoA decarboxylase
PDB Code: 2YGW
Target Class: Miscellaneous
Target: MLYCD
Disease Area: metabolism
Date Deposited: 2011-04-21

Name: Human Methylmalonyl-CoA epimerase
PDB Code: 3RMU
Target Class: Oxidoreductases
Target: MCEE
Disease Area:
Date Deposited: 2011-04-21

Name: Human Glycogenin-1 T83M mutant in complex with manganese and UDP
PDB Code: 3RMV
Target Class: Miscellaneous
Target: GYG1
Disease Area:
Date Deposited: 2011-04-21

Name: Human Glycogenin-1 T83M mutant in complex with manganese and UDP-glucose
PDB Code: 3RMW
Target Class: Miscellaneous
Target: GYG1
Disease Area:
Date Deposited: 2011-04-21

Name: Human HECT domain containing 1, helical bundle domain
PDB Code: 2LC3
Target Class: Ubiquitylation
Target: HECTD1
Disease Area: signalling
Date Deposited: 2011-04-15

Name: Human Myotubularin related protein 6 (MTMR6)
PDB Code: 2YF0
Target Class: Phosphoinosotide dependent signalling
Target: MTMR6
Disease Area: signalling
Date Deposited: 2011-03-31

Name: Human MLH1 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), DNA-mismatch domain
PDB Code: 3RBN
Target Class: Miscellaneous
Target: MLH1
Disease Area: cancer, chromatin and epigenetics
Date Deposited: 2011-03-31

Name: Human PR domain containing 11, methyltransferase domain
PDB Code: 3RAY
Target Class: Transferases
Target: PRMD11
Disease Area: chromatin and epigenetics
Date Deposited: 2011-03-31

Name: Human BRD1 (bromodomain)
PDB Code: 3RCW
Target Class: Bromodomain
Target: BRD1
Disease Area:
Date Deposited: 2011-03-31

Name: Human aspartate beta-hydroxylase isoform a
PDB Code: 3RCQ
Target Class: Oxidoreductases
Target: ASPH
Disease Area: cancer
Date Deposited: 2011-03-31

Name: Human phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PDB Code: 2YBX
Target Class: Protein Kinase
Target: PIP4K2A
Disease Area: neurobiology
Date Deposited: 2011-03-30

Name: Human tudor domain containing 7, N-terminal domain
PDB Code: 3RCO
Target Class: Methyl-lysine readers
Target: TDRD7
Disease Area: chromatin and epigenetics
Date Deposited: 2011-03-30

Name: Human cdc-2 like kinase 3 in complex with leucettine L₄₁
PDB Code: 3RAW
Target Class: Protein Kinase
Target: CLK3
Disease Area: signalling, neurobiology
Date Deposited: 2011-03-28

Name: Human malignant T cell amplified sequence 1
PDB Code: 3R90
Target Class: Miscellaneous
Target: MCTS1
Disease Area: cancer
Date Deposited: 2011-03-24