SGC | STRUCTURES GALLERY

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624 structures for iSee collection

Name: Human growth hormone releasing hormone receptor (extracellular domain)
PDB Code: 2XDG
Target Class: Membrane proteins
Target: GHRHR
Disease Area:
Date Deposited: Apr 30 2010

[?]

Name: Human pleckstrin homology domain interacting protein (2nd bromodomain)
PDB Code: 3MB3
Target Class: Bromodomain
Target: PHIP
Disease Area:
Date Deposited: Mar 25 2010

[?]

Name: Human Vasoactive Intestinal Peptide Receptor 2 - GPCR extracellular domain
PDB Code: 2X57
Target Class: Membrane proteins
Target: VIPR2 (GPCR extracellular domain)
Disease Area:
Date Deposited: Feb 05 2010

[?]

Name: Human macro domain 1
PDB Code: 2X47
Target Class: Miscellaneous
Target: MACROD1
Disease Area: metabolism, chromatin and epigenetics, signalling
Date Deposited: Jan 28 2010

[?]

Name: Human aspartyl aminopeptidase
PDB Code: 3L6S
Target Class: Proteases
Target: DNPEP
Disease Area:
Date Deposited: Dec 24 2009

[?]

Name: Human hydroxysteroid dehydrogenase like 2
PDB Code: 3KVO
Target Class: Oxidoreductases
Target: SDHL
Disease Area:
Date Deposited: Nov 30 2009

[?]

Name: Human ral guanine nucleotide dissociation stimulator, RAS-associating domain
PDB Code: 3KH0
Target Class: G-Protein Regulators
Target: RALGDS
Disease Area: cancer
Date Deposited: Oct 30 2009

[?]

Name: Human plant homeodomain finger protein 8
PDB Code: 2WWU
Target Class: Oxidoreductases
Target: PHF8
Disease Area: chromatin and epigenetics, neurobiology
Date Deposited: Oct 29 2009

[?]

Name: Human tight junction protein 3 (zona occludens 3), kinase domain
PDB Code: 3KFV
Target Class: Non-protein Kinase
Target: TJP3
Disease Area:
Date Deposited: Oct 28 2009

[?]

Name: Human phosphatidylserine receptor beta
PDB Code: 3K2O
Target Class: Oxidoreductases
Target: PTDSR
Disease Area: signalling
Date Deposited: Sep 30 2009

[?]

Name: Plasmodium falciparum CDPK3 (PFC0420w), CAD domain
PDB Code: 3K21
Target Class: Protein Kinase
Target: CDPK3
Disease Area: parasitic disease
Date Deposited: Sep 29 2009

[?]

Name: Plasmodium falciparum SIR2A (PF13_0152) in complex with AMP
PDB Code: 3JWP
Target Class: Miscellaneous
Target: SIR2A
Disease Area: parasitic disease
Date Deposited: Sep 18 2009

[?]

Name: Human embryonic ectoderm development (EED) in complex with a trimethylated H4K20 peptide
PDB Code: 3JPX
Target Class: Miscellaneous
Target: EED
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Sep 04 2009

[?]

Name: Human D4, zinc and double PHD fingers family 2 - zinc finger domain
PDB Code: 3IUF
Target Class: Miscellaneous
Target: DPF2
Disease Area: cancer
Date Deposited: Aug 31 2009

[?]

Name: Human glutamate-oxaloacetate transaminase 1
PDB Code: 3II0
Target Class: Miscellaneous
Target: GOT1
Disease Area: metabolism
Date Deposited: Jul 31 2009

[?]

Name: Human ubiquitin specific peptidase 5 in covalent complex with ubiquitin
PDB Code: 3IHP
Target Class: Ubiquitylation
Target: USP5
Disease Area: signalling
Date Deposited: Jul 31 2009

[?]

Name: Plasmodium falciparum HSP90, N-terminal domain, in complex with ADP analog
PDB Code: 3IED
Target Class: Miscellaneous
Target: HSP90
Disease Area: parasitic disease
Date Deposited: Jul 22 2009

[?]

Name: Human E3 Ligase GRAIL, PA domain
PDB Code: 3ICU
Target Class: Ubiquitylation
Target: RNF128
Disease Area: metabolism, signalling
Date Deposited: Jul 18 2009

[?]

Name: Human WD repeat domain 92, WD repeats domain
PDB Code: 3I2N
Target Class: Miscellaneous
Target: WDR92
Disease Area: Cancer, Chromatin and Epigenetics
Date Deposited: Jun 30 2009

[?]

Name: Toxoplasma gondii CDPK3, TGME49_105860
PDB Code: 3HZT
Target Class: Malaria
Target: CDPK3
Disease Area: Parasitic Disease
Date Deposited: Jun 24 2009

[?]

Name: Toxoplasma gondii CDPK1, TGME49_101440, in presence of calcium
PDB Code: 3HX4
Target Class: Malaria
Target: CDPK1
Disease Area: Parasitic Disease
Date Deposited: Jun 19 2009

[?]

Name: Human v-abl Abelson murine leukemia viral oncogene homolog 2 in complex with K00546
PDB Code: 3HMI
Target Class: Protein Kinase
Target: ABL2 + K00546
Disease Area: cancer, signalling, neurobiology
Date Deposited: May 29 2009

[?]

Name: Human plexin B1, cytoplasminc domain
PDB Code: 3HM6
Target Class: G-Protein Regulators
Target: PLXNB1
Disease Area: Cancer
Date Deposited: May 28 2009

[?]

Name: Human hexokinase 3, C-terminal hexokinase domain
PDB Code: 3HM8
Target Class: Non-protein Kinase
Target: HK3
Disease Area: Metabolism
Date Deposited: May 28 2009

[?]

Name: Human type I activin receptor (kinase domain) in complex with FKBP12 and dorsomorphin
PDB Code: 3H9R
Target Class: Protein Kinase
Target: ACVR1 + FKBP12 + dorsomorphin
Disease Area:
Date Deposited: Apr 30 2009

[?]

Name: Human ring finger protein 2, C-terminal domain
PDB Code: 3H8H
Target Class: Ubiquitylation
Target: RNF2
Disease Area: Cancer, Chromatin and Epigenetics
Date Deposited: Apr 29 2009

[?]

Name: Human ubiquitin-like modifier activating enzyme 5 in complex with ATP
PDB Code: 3H8V
Target Class: Ubiquitylation
Target: UBA5
Disease Area: Signalling
Date Deposited: Apr 29 2009

[?]

Name: Human fragile X mental retardation, autosomal homolog 2, Tudor domains
PDB Code: 3H8Z
Target Class: Methyl-lysine readers
Target: FXR2
Disease Area: Cancer, Chromatin and Epigenetics
Date Deposited: Apr 29 2009

[?]

Name: Human v-abl Abelson murine leukemia viral oncogene homolog 2 in complex with imatinib (Gleevec)
PDB Code: 3GVU
Target Class: Protein Kinase
Target: ABL2 + imatinib (Gleevec)
Disease Area:
Date Deposited: Mar 31 2009

[?]

Name: Human palmitoyl-protein thioesterase 1
PDB Code: 3GRO
Target Class: Miscellaneous
Target: PPT1
Disease Area:
Date Deposited: Mar 31 2009

[?]

Name: Human ubiquitin-like modifier activating enzyme 5 in complex with AMPPNP
PDB Code: 3GUC
Target Class: Ubiquitylation
Target: UBA5
Disease Area: Signalling
Date Deposited: Mar 30 2009

[?]

Name: Trypanosoma brucei UDP-glucose phosphorylase
PDB Code: 3GUE
Target Class: Miscellaneous
Target: Tb10.389.0330
Disease Area: Metabolism, parasitic disease
Date Deposited: Mar 29 2009

[?]

Name: Human MST4 (Mst3 and SOK1-related kinase)
PDB Code: 3GGF
Target Class: Protein Kinase
Target: MST4
Disease Area: cancer
Date Deposited: Feb 28 2009

[?]

Name: Human TTK protein kinase in complex with pyrrolopyridine
PDB Code: 3GFW
Target Class: Protein Kinase
Target: TTK + pyrrolopyridine
Disease Area: cancer, signalling
Date Deposited: Feb 27 2009

[?]

Name: Human Intersectin 2, RhoGEF domain
PDB Code: 3GF9
Target Class: G-Protein Regulators
Target: ITSN2
Disease Area: Neurobiology, Signalling
Date Deposited: Feb 26 2009

[?]

Name: Human kinesin KIF13B, motor domain, in complex with ADP
PDB Code: 3GBJ
Target Class: Miscellaneous
Target: KIF13B
Disease Area: Cancer, Neurobiology
Date Deposited: Feb 19 2009

[?]

Name: Human pyruvate kinase, muscle, S437Y variant
PDB Code: 3G2G
Target Class: Non-protein Kinase
Target: PKM2
Disease Area: Cancer
Date Deposited: Jan 31 2009

[?]

Name: Human bromodomain adjacent to zinc finger domain, 2B
PDB Code: 3G0L
Target Class: Bromodomain
Target: BAZ2B
Disease Area:
Date Deposited: Jan 28 2009

[?]

Name: Plasmodium falciparum putative bolA-like protein PFE0790c
PDB Code: 2KDN
Target Class: Miscellaneous
Target: PFE0790c
Disease Area: Parasitic Disease
Date Deposited: Jan 12 2009

[?]

Name: Trypanosoma brucei CTP synthetase - glutaminase domain in complex with acivicin
PDB Code: 2W7T
Target Class: Nucleotide metabolism
Target: TBCTPS
Disease Area: parasitic disease
Date Deposited: Dec 30 2008

[?]

Name: Human sorting nexin-17, PX domain
PDB Code: 3FOG
Target Class: Phosphoinosotide dependent signalling
Target: SNX17
Disease Area:
Date Deposited: Dec 30 2008

[?]

Name: Human START domain of Acyl-coenzyme A thioesterase 11
PDB Code: 3FO5
Target Class: Lipid signalling
Target: ACOT11
Disease Area:
Date Deposited: Dec 27 2008

[?]

Name: Human haspin in complex with an isoquinoline
PDB Code: 3FMD
Target Class: Protein Kinase
Target: GSG2 + K00084
Disease Area: chromatin and epigenetics, signalling
Date Deposited: Dec 21 2008

[?]

Name: Human dCMP deaminase
PDB Code: 2W4L
Target Class: Nucleotide metabolism
Target: DCTD
Disease Area: cancer
Date Deposited: Nov 28 2008

[?]

Name: human calcium/calmodulin-dependent protein kinase IV in complex with K00546
PDB Code: 2W4O
Target Class: Protein Kinase
Target: CAMK4
Disease Area: signalling
Date Deposited: Nov 28 2008

[?]

Name: Human DEAD box RNA helicase DDX5 (p68)
PDB Code: 3FE2
Target Class: ATPases
Target: DDX5
Disease Area: cancer
Date Deposited: Nov 27 2008

[?]

Name: Human heat shock 70kDa protein 6 (HSP70B)
PDB Code: 3FE1
Target Class: ATPases
Target: HSPA6
Disease Area: cancer
Date Deposited: Nov 27 2008

[?]

Name: Human choline kinase alpha in complex with hemicholinium-3 and ADP
PDB Code: 3G15
Target Class: Non-protein Kinase
Target: CHKA
Disease Area: cancer
Date Deposited: Oct 31 2008

[?]

Name: Human jumonji domain containing 2E in complex with 2,4-PDCA
PDB Code: 2W2I
Target Class: Miscellaneous
Target: JMJD2E (LOC390245) + 2,4-PDCA
Disease Area: chromatin and epigenetics
Date Deposited: Oct 31 2008

[?]

Name: Human haspin in complex with an Imidazo-pyridazine ligand
PDB Code: 3F2N
Target Class: Protein Kinase
Target: GSG2 + K00508
Disease Area: chromatin and epigenetics, signalling
Date Deposited: Oct 30 2008

[?]

Name: Human SPRY domain-containing SOCS box protein SSB-1 in complex with peptide
PDB Code: 3F2O
Target Class: SOCS-box-containing
Target: SPSB1
Disease Area: signalling
Date Deposited: Oct 30 2008

[?]

Name: Human NUMB-like protein, phosphotyrosine interaction domain
PDB Code: 3F0W
Target Class: Miscellaneous
Target: NUMBL
Disease Area: neurobiology
Date Deposited: Oct 27 2008

[?]

Name: Plasmodium vivax geranylgeranylpyrophosphate synthase in complex with IPP and zoledronate
PDB Code: 3EZ3
Target Class: Transferases
Target: PvGGPPS
Disease Area: parasitic disease
Date Deposited: Oct 22 2008

[?]

Name: Human DEAD-box RNA-helicase DDX19 in complex with ADP
PDB Code: 3EWS
Target Class: ATPases
Target: DDX19
Disease Area: cancer
Date Deposited: Oct 16 2008

[?]

Name: Human SKI-like
PDB Code: 3EQ5
Target Class: Signalling proteins
Target: SKIL
Disease Area: cancer
Date Deposited: Sep 30 2008

[?]

Name: Human CTP synthetase 2 - glutaminase domain in complex with 5-OXO-L-NORLEUCINE
PDB Code: 2V4U
Target Class: Nucleotide metabolism
Target: CTPS2
Disease Area: cancer
Date Deposited: Sep 29 2008

[?]

Name: Human neuroepithelial cell transforming gene 1 isoform 1
PDB Code: 3EO2
Target Class: G-Protein Regulators
Target: NET1
Disease Area: cancer, neurobiology
Date Deposited: Sep 26 2008

[?]

Name: Human Glutamine-Fructose-6-Phosphate Transaminase 1 (GFPT1)
PDB Code: 2V4M
Target Class: Amino oxidases
Target: GFPT1
Disease Area:
Date Deposited: Sep 26 2008

[?]

Name: Human glucosamine (UDP-N-acetyl)-2-epimerase-N-acetylmannosamine kinase
PDB Code: 3EO3
Target Class: Non-protein Kinase
Target: GNE
Disease Area: metabolism, cancer
Date Deposited: Sep 26 2008

[?]

Name: Human CTP:Phosphoethanolamine Cytidylyltransferase
PDB Code: 3ELB
Target Class: AA metabolic enzymes
Target: PCYT2
Disease Area: cancer
Date Deposited: Sep 22 2008

[?]

Name: Human phosphogluconate dehydrogenase
PDB Code: 2JKV
Target Class: Miscellaneous
Target: PGD
Disease Area:
Date Deposited: Aug 31 2008

[?]

Name: Human microtubule-associated protein 1 light chain 3 alpha isoform a [Homo sapiens]
PDB Code: 3ECI
Target Class: ubiquitin family
Target: MAP1LC3A
Disease Area:
Date Deposited: Aug 30 2008

[?]

Name: Human FLJ10324 (RADIL), RA domain
PDB Code: 3EC8
Target Class: Cell-type specific expression
Target: FLJ10324
Disease Area:
Date Deposited: Aug 29 2008

[?]

Name: Human hypothetical protein LOC27351
PDB Code: 3EBQ
Target Class: ubiquitin family
Target: PPPDE1
Disease Area:
Date Deposited: Aug 28 2008

[?]

Name: Human phospholipase A2-activating protein isoform 1 PUL domain in complex with P97 C-terminal peptide
PDB Code: 3EBB
Target Class: ubiquitin family
Target: PLAA
Disease Area: neurobiology
Date Deposited: Aug 27 2008

[?]

Name: Human Rho GTPase activating protein 11A, RhoGAP domain
PDB Code: 3EAP
Target Class: GTPases
Target: ARHGAP11A
Disease Area: signalling, neurobiology
Date Deposited: Aug 26 2008

[?]

Name: Human SPRY domain-containing SOCS box protein SSB-1
PDB Code: 2JK9
Target Class: SOCS-box-containing
Target: SPSB1
Disease Area: signalling
Date Deposited: Aug 22 2008

[?]

Name: Human haspin in complex with a pyrazole-pyridazine ligand
PDB Code: 3E7V
Target Class: Protein Kinase
Target: GSG2 + K00522
Disease Area: chromatin and epigenetics
Date Deposited: Aug 19 2008

[?]

Name: Human PTK9L protein tyrosine kinase 9-like (2nd ADF-H domain)
PDB Code: 2W0I
Target Class: Signalling proteins
Target: PTK9L (2nd ADF-H domain)
Disease Area: signalling
Date Deposited: Aug 18 2008

[?]

Name: human chromosome 6 open reading frame 197 [Homo sapiens]
PDB Code: 3DZX
Target Class: G-Protein Regulators
Target: TBC1D22B
Disease Area:
Date Deposited: Jul 30 2008

[?]

Name: Human RAB3B, member RAS oncogene family
PDB Code: 3DZ8
Target Class: GTPases
Target: RAB3B
Disease Area: cancer, signalling
Date Deposited: Jul 29 2008

[?]

Name: Human tyrosine aminotransferase
PDB Code: 3DYD
Target Class: AA metabolic enzymes
Target: TAT
Disease Area:
Date Deposited: Jul 27 2008

[?]

Name: Human CREB binding protein (bromodomain)
PDB Code: 3DWY
Target Class: Bromodomain
Target: CREBBP (bromodomain)
Disease Area:
Date Deposited: Jul 23 2008

[?]

Name: Human ADP-ribosylation factor GTPase activating protein 1
PDB Code: 3DWD
Target Class: G-Protein Regulators
Target: ARFGAP1
Disease Area: cancer, neurobiology
Date Deposited: Jul 22 2008

[?]

Name: Human guanine monophosphate synthetase
PDB Code: 2VXO
Target Class: Nucleotide metabolism
Target: GMPS
Disease Area: cancer
Date Deposited: Jul 08 2008

[?]

Name: Human chromobox homolog 3 in complex with a tri-methylated lysine peptide
PDB Code: 3DM1
Target Class: Methyl-lysine readers
Target: CBX3
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Jun 30 2008

[?]

Name: Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A in complex with K00611a
PDB Code: 2VX3
Target Class: Protein Kinase
Target: DYRK1A + K00611a
Disease Area: signalling, neurobiology
Date Deposited: Jun 30 2008

[?]

Name: Human haspin in complex with AMP
PDB Code: 3DLZ
Target Class: Protein Kinase
Target: GSG2 + AMP
Disease Area: chromatin and epigenetics, signalling
Date Deposited: Jun 30 2008

[?]

Name: Human DEAD-box RNA-helicase DDX52, conserved domain I in complex with ADP
PDB Code: 3DKP
Target Class: ATPases
Target: DDX52
Disease Area: cancer
Date Deposited: Jun 25 2008

[?]

Name: Human HECTD1 CPH Domain
PDB Code: 3DKM
Target Class: ubiquitin family
Target: HECTD1
Disease Area: signalling
Date Deposited: Jun 25 2008

[?]

Name: Human ephrin type-A receptor 7 kinase domain in complex with inhibitor ALW-II-49-7
PDB Code: 3DKO
Target Class: Protein Kinase
Target: EPHA7
Disease Area: cancer, signalling
Date Deposited: Jun 25 2008

[?]

Name: Human tRNA-specific adenosine-34 deaminase subunit ADAT2
PDB Code: 3DH1
Target Class: Nucleotide metabolism
Target: DEADC1
Disease Area:
Date Deposited: Jun 17 2008

[?]

Name: Human Ribonucleotide reductase, subunit M2 B
PDB Code: 2VUX
Target Class: Nucleotide metabolism
Target: RRM2B
Disease Area: metabolism, cancer
Date Deposited: May 31 2008

[?]

Name: Human haspin in complex with 5-Iodotubercidin
PDB Code: 2VUW
Target Class: Protein Kinase
Target: GSG2 + K00224
Disease Area: chromatin and epigenetics, signalling
Date Deposited: May 30 2008

[?]

Name: Human two AAA domain containing protein
PDB Code: 3DAI
Target Class: Bromodomain
Target: ATAD2
Disease Area: chromatin and epigenetics, signalling
Date Deposited: May 29 2008

[?]

Name: Human UHRF1, tandem tudor domain
PDB Code: 3DB4
Target Class: Miscellaneous
Target: UHRF1
Disease Area: cancer, chromatin and epigenetics, signalling
Date Deposited: May 29 2008

[?]

Name: Human UHRF1, tandem tudor domain, in complex with H3K9 peptide
PDB Code: 3DB3
Target Class: Miscellaneous
Target: UHRF1
Disease Area: cancer, chromatin and epigenetics, signalling
Date Deposited: May 29 2008

[?]

Name: Human carbonic anhydrase XIII
PDB Code: 3DA2
Target Class: Miscellaneous
Target: CA13
Disease Area: metabolism, signalling
Date Deposited: May 28 2008

[?]

Name: Human Fidgetin-like 1
PDB Code: 3D8B
Target Class: ATPases
Target: FIGNL1
Disease Area:
Date Deposited: May 23 2008

[?]

Name: Human GCN5 general control of amino-acid synthesis 5-like 2
PDB Code: 3D7C
Target Class: Bromodomain
Target: GCN5L2
Disease Area:
Date Deposited: May 21 2008

[?]

Name: Human dual specificity phosphatase 16
PDB Code: 2VSW
Target Class: Phosphatases
Target: DUSP16
Disease Area: signalling
Date Deposited: Apr 30 2008

[?]

Name: Human ephrin receptor EPHA2 in complex with ephrin A1 isoform a precursor
PDB Code: 3CZU
Target Class: Protein Kinase
Target: EPHA2-EFNA1 complex
Disease Area: cancer, signalling
Date Deposited: Apr 30 2008

[?]

Name: Human glutaminase
PDB Code: 3CZD
Target Class: AA metabolic enzymes
Target: GLS
Disease Area: cancer
Date Deposited: Apr 29 2008

[?]

Name: Human glutathione peroxidase 8
PDB Code: 3CYN
Target Class: Oxidoreductases
Target: LOC493869 (GPX8)
Disease Area:
Date Deposited: Apr 25 2008

[?]

Name: Human chimerin 1
PDB Code: 3CXL
Target Class: G-Protein Regulators
Target: CHN1
Disease Area: neurobiology
Date Deposited: Apr 24 2008

[?]

Name: Human nuclear receptor subfamily 1, group D, member 2 in complex with heme
PDB Code: 3CQV
Target Class: Miscellaneous
Target: NR1D2
Disease Area: metabolism, cancer, drug metabolism and toxicology
Date Deposited: Apr 03 2008

[?]

Name: Human eukaryotic translation initiation factor 5A
PDB Code: 3CPF
Target Class: G-Protein Regulators
Target: EIF5A
Disease Area: cancer
Date Deposited: Mar 31 2008

[?]

Name: Human peroxisomal delta3,5, delta2,4-dienoyl CoA isomerase
PDB Code: 2VRE
Target Class: Miscellaneous
Target: ECH1
Disease Area:
Date Deposited: Mar 31 2008

[?]

Name: Human class II alcohol dehydrogenase in complex with NAD and Zn
PDB Code: 3COS
Target Class: Oxidoreductases
Target: ADH4
Disease Area:
Date Deposited: Mar 31 2008

[?]

Name: Human farnesyl diphosphate synthase in complex with NE58025
PDB Code: 3CP6
Target Class: Miscellaneous
Target: FDPS + NE58025
Disease Area: metabolism, signalling
Date Deposited: Mar 31 2008

[?]

Name: Human Protein Receptor Tyrosine Phosphatase E
PDB Code: 2JJD
Target Class: Phosphatases
Target: PTPRE
Disease Area: metabolism, signalling, neurobiology
Date Deposited: Mar 31 2008

[?]

Name: Human Nudix motif 16 (NUDT16)
PDB Code: 3COU
Target Class: Nucleotide metabolism
Target: NUDT16
Disease Area: cancer
Date Deposited: Mar 29 2008

[?]

Name: Human neuroblastoma RAS viral (v-ras) oncogene homolog in complex with GDP
PDB Code: 3CON
Target Class: GTPases
Target: NRAS
Disease Area: cancer, signalling
Date Deposited: Mar 28 2008

[?]

Name: Human chromobox homolog 4 [Homo sapiens]
PDB Code: 2K28
Target Class: Methyl-lysine readers
Target: CBX4
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Mar 27 2008

[?]

Name: Human Dihydropyrimidinase
PDB Code: 2VR2
Target Class: Oxidoreductases
Target: DHP
Disease Area: drug metabolism and toxicology
Date Deposited: Mar 25 2008

[?]

Name: Human Set and Ring associated (SRA) domain of UHRF1 bound to methylated DNA
PDB Code: 3CLZ
Target Class: ubiquitin family
Target: UHRF1
Disease Area: cancer, chromatin and epigenetics, signalling
Date Deposited: Mar 20 2008

[?]

Name: Human cytosolic sulfotransferase, sub-family 1B, cember 1 in complex with PAP and Resveratrol
PDB Code: 3CKL
Target Class: Transferases
Target: SULT1B1
Disease Area: metabolism, cancer, drug metabolism and toxicology
Date Deposited: Mar 16 2008

[?]

Name: Human methyltransferase like 1 in complex with SAM
PDB Code: 3CKK
Target Class: Transferases
Target: METTL1
Disease Area: metabolism
Date Deposited: Mar 16 2008

[?]

Name: Human baculoviral IAP repeat-containing 6, Ubiquitin-conjugating domain
PDB Code: 3CEG
Target Class: Apoptosisubiquitin family
Target: BIRC6
Disease Area: cancer, signalling
Date Deposited: Feb 29 2008

[?]

Name: Human guanine monophosphate synthetase - glutaminase domain
PDB Code: 2VPI
Target Class: Nucleotide metabolism
Target: GMPS
Disease Area: cancer
Date Deposited: Feb 29 2008

[?]

Name: Human TTK protein kinase
PDB Code: 3CEK
Target Class: Protein Kinase
Target: TTK
Disease Area: signalling
Date Deposited: Feb 29 2008

[?]

Name: Human kelch-like 12
PDB Code: 2VPJ
Target Class: BTB-Kelch
Target: KLHL12
Disease Area: signalling
Date Deposited: Feb 29 2008

[?]

Name: Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor PJ34
PDB Code: 3CE0
Target Class: Poly ADP-ribose polymerase
Target: PARP3
Disease Area: cancer
Date Deposited: Feb 28 2008

[?]

Name: Human chromobox homolog 7
PDB Code: 2K1B
Target Class: Methyl-lysine readers
Target: CBX7
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Feb 25 2008

[?]

Name: Human Protein Tyrosine Kinase 2 Beta
PDB Code: 3CC6
Target Class: Protein Kinase
Target: PTK2B
Disease Area: metabolism
Date Deposited: Feb 25 2008

[?]

Name: Human REM2 RAS (RAD and GEM)-like GTP binding 2 in complex with GDP
PDB Code: 3CBQ
Target Class: GTPases
Target: REM2
Disease Area: metabolism, signalling
Date Deposited: Feb 22 2008

[?]

Name: Human EPH receptor A2 ligand binding domain
PDB Code: 3C8X
Target Class: Protein Kinase
Target: EPHA2
Disease Area: cancer, signalling
Date Deposited: Feb 14 2008

[?]

Name: Human RAS-like, family 12 protein in complex with GDP
PDB Code: 3C5C
Target Class: GTPases
Target: RASL12
Disease Area: signalling
Date Deposited: Jan 31 2008

[?]

Name: Human glucocorticoid receptor DNA binding factor 1 isoform b in complex with a GTP analogue
PDB Code: 3C5H
Target Class: GTPases
Target: GRLF1
Disease Area: cancer
Date Deposited: Jan 31 2008

[?]

Name: Human xenobiotic/medium-chain fatty acid:CoA ligase in complex with ATP/AMP
PDB Code: 3C5E
Target Class: Miscellaneous
Target: LOC148158 + ATP/AMP
Disease Area: metabolism, drug metabolism and toxicology
Date Deposited: Jan 31 2008

[?]

Name: Human reticulon 4 interacting protein 1 in complex with NADPH
PDB Code: 2VN8
Target Class: Oxidoreductases
Target: RTN4IP1 + NADPH
Disease Area: signalling, neurobiology
Date Deposited: Jan 31 2008

[?]

Name: Human zinc binding alcohol dehydrogenase, domain containing 1
PDB Code: 2VNA
Target Class: Oxidoreductases
Target: ZADH1
Disease Area: metabolism
Date Deposited: Jan 31 2008

[?]

Name: Human histone deacetylase 6 zinc finger domain
PDB Code: 3C5K
Target Class: Miscellaneous
Target: HDAC6
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Jan 31 2008

[?]

Name: Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor KU0058948
PDB Code: 3C49
Target Class: Poly ADP-ribose polymerase
Target: PARP3
Disease Area: cancer
Date Deposited: Jan 30 2008

[?]

Name: Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor DR2313
PDB Code: 3C4H
Target Class: Poly ADP-ribose polymerase
Target: PARP3
Disease Area: cancer
Date Deposited: Jan 30 2008

[?]

Name: Human Bcl2-A1 in complex with BIM-BH3 peptide
PDB Code: 2VM6
Target Class: Apoptosis
Target: BCL2A1
Disease Area: cancer, signalling, neurobiology
Date Deposited: Jan 23 2008

[?]

Name: Human baculoviral inhibitor of apoptosis repeat-containing protein 1 (BIRC1), BIR2 domain
PDB Code: 2VM5
Target Class: Apoptosis
Target: BIRC1
Disease Area: cancer, signalling, neurobiology
Date Deposited: Jan 23 2008

[?]

Name: Human ubiquitin-conjugating enzyme UBCH6
PDB Code: 3BZH
Target Class: ubiquitin family
Target: UBE2E1
Disease Area: signalling
Date Deposited: Jan 17 2008

[?]

Name: Human OTU domain, ubiquitin aldehyde binding 1 [Homo sapiens]
PDB Code: 2ZFY
Target Class: ubiquitin family
Target: OTUB1
Disease Area: signalling
Date Deposited: Jan 16 2008

[?]

Name: Human CTP synthetase 2 - glutaminase domain
PDB Code: 2VKT
Target Class: Nucleotide metabolism
Target: CTPS2
Disease Area: cancer
Date Deposited: Dec 28 2007

[?]

Name: Human BTB domain protein BDPL
PDB Code: 2VKP
Target Class: BTB-Kelch
Target: BTBD6
Disease Area:
Date Deposited: Dec 21 2007

[?]

Name: Human membrane associated guanylate kinase, WW and PDZ domain containing 1 (6th domain)
PDB Code: 3BPU
Target Class: Linkers
Target: MAGI1
Disease Area: neurobiology
Date Deposited: Dec 19 2007

[?]

Name: Human MER kinase domain in complex with 2-(2-hydroxyethylamino)-6-(3-chloroanilino)-9isopropylpurine
PDB Code: 3BPR
Target Class: Protein Kinase
Target: MERTK
Disease Area: cancer, signalling
Date Deposited: Dec 18 2007

[?]

Name: Human Histone-lysine N-methyltransferase SETMAR methyltransferase domain in complex with AdoHcy
PDB Code: 3BO5
Target Class: Transferases
Target: SETMAR
Disease Area: cancer
Date Deposited: Dec 17 2007

[?]

Name: Human Poly(ADP-Ribose) Polymerase15
PDB Code: 3BLJ
Target Class: Poly ADP-ribose polymerase
Target: PARP15
Disease Area: cancer
Date Deposited: Dec 11 2007

[?]

Name: Human short-chain acyl CoA dehydrogenase
PDB Code: 2VIG
Target Class: Oxidoreductases
Target: ACADS
Disease Area: metabolism, neurobiology
Date Deposited: Nov 30 2007

[?]

Name: Human suppressor of cytokine signaling 6: SH2 complex with c-KIT phosphopeptide
PDB Code: 2VIF
Target Class: SOCS-box-containing
Target: SOCS6 + phosphopeptide
Disease Area: metabolism, signalling
Date Deposited: Nov 30 2007

[?]

Name: Human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein - Ubiquitin-like domain
PDB Code: 2JXX
Target Class: ubiquitin family
Target: NFATC2IP
Disease Area: signalling
Date Deposited: Nov 30 2007

[?]

Name: Human Thiamine Triphosphatase
PDB Code: 3BHD
Target Class: Phosphatases
Target: THTPA
Disease Area: metabolism
Date Deposited: Nov 28 2007

[?]

Name: Human RNA (guanine-N7-) methyltransferase in complex with S-(5
PDB Code: 3BGV
Target Class: Transferases
Target: RNMT
Disease Area: cancer
Date Deposited: Nov 27 2007

[?]

Name: Human kinesin family member 22 in complex with ADP
PDB Code: 3BFN
Target Class: Miscellaneous
Target: KIF22
Disease Area: cancer
Date Deposited: Nov 22 2007

[?]

Name: Human mucosa associated lymphoid tissue lymphoma translocation gene 1 (Malt1) immunoglobulin-like domain
PDB Code: 3BFO
Target Class: Proteases
Target: MALT1
Disease Area: cancer
Date Deposited: Nov 22 2007

[?]

Name: Human DEAD-box RNA-helicase DDX47, conserved domain I in complex with AMP
PDB Code: 3BER
Target Class: ATPases
Target: DDX47
Disease Area: cancer
Date Deposited: Nov 20 2007

[?]

Name: Human Acyl-coenzyme A thioesterase 12
PDB Code: 3B7K
Target Class: Lipid signalling
Target: ACOT12
Disease Area:
Date Deposited: Oct 31 2007

[?]

Name: Human farnesyl diphosphate synthase in complex with minodronate
PDB Code: 3B7L
Target Class: Miscellaneous
Target: FDPS + minodronate
Disease Area: metabolism, signalling
Date Deposited: Oct 31 2007

[?]

Name: Human xenobiotic/medium-chain fatty acid:CoA ligase
PDB Code: 3B7W
Target Class: Miscellaneous
Target: LOC148158
Disease Area: metabolism, drug metabolism and toxicology
Date Deposited: Oct 31 2007

[?]

Name: Human protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)
PDB Code: 3B7O
Target Class: Phosphatases
Target: PTPN11
Disease Area:
Date Deposited: Oct 31 2007

[?]

Name: Human GLI-Krüppel family member HKR3
PDB Code: 3B84
Target Class: BTB-Kelch
Target: HKR3
Disease Area:
Date Deposited: Oct 31 2007

[?]

Name: Human E3 ubiquitin-protein hect ligase NEDD4 C2 domain
PDB Code: 3B7Y
Target Class: ubiquitin family
Target: NEDD4
Disease Area: signalling, neurobiology
Date Deposited: Oct 31 2007

[?]

Name: Human FK506-binding protein 6
PDB Code: 3B7X
Target Class: isomerases
Target: FKBP6
Disease Area: signalling
Date Deposited: Oct 31 2007

[?]

Name: Human DECH-box RNA Helicase MDA5, DECH-domain
PDB Code: 3B6E
Target Class: ATPases
Target: MDA5
Disease Area: cancer
Date Deposited: Oct 29 2007

[?]

Name: Human kinesin family member 3B bound to ADP
PDB Code: 3B6U
Target Class: Miscellaneous
Target: KIF3B
Disease Area:
Date Deposited: Oct 29 2007

[?]

Name: Cryptosporidium parvum GTPase, putative Rab1a
PDB Code: 2RHD
Target Class: Malaria
Target: Cp-Rab1a
Disease Area: parasitic disease
Date Deposited: Oct 09 2007

[?]

Name: Human myotonin-protein kinase, Form I
PDB Code: 2VD5
Target Class: Protein Kinase
Target: DMPK1
Disease Area: signalling
Date Deposited: Sep 30 2007

[?]

Name: Human bromodomain, testis-specific [isoform a; tv1]
PDB Code: 2RFJ
Target Class: Bromodomain
Target: BRDT
Disease Area:
Date Deposited: Sep 30 2007

[?]

Name: Human jumonji domain containing 2A in complex with inhibitor
PDB Code: 2VD7
Target Class: Miscellaneous
Target: JMJD2A + inhibitor
Disease Area: chromatin and epigenetics
Date Deposited: Sep 30 2007

[?]

Name: Human Tankyrase 1 - catalytic PARP-domain
PDB Code: 2RF5
Target Class: Poly ADP-ribose polymerase
Target: TNKS1
Disease Area: cancer
Date Deposited: Sep 28 2007

[?]

Name: Human plexin B1 - Rho family GTPase 1 complex
PDB Code: 2REX
Target Class: GTPases
Target: PLXNB1 + RND1
Disease Area: cancer
Date Deposited: Sep 27 2007

[?]

Name: Human mitogen-activated protein kinase kinase kinase 10 (SH3 domain)
PDB Code: 2RF0
Target Class: KinasesLinkers
Target: MAP3K10
Disease Area:
Date Deposited: Sep 27 2007

[?]

Name: Human sulfotransferase family, cytosolic, 1C, member 3
PDB Code: 2REO
Target Class: Transferases
Target: SULT1C3
Disease Area: drug metabolism and toxicology
Date Deposited: Sep 26 2007

[?]

Name: Human kinesin family member C1
PDB Code: 2REP
Target Class: Miscellaneous
Target: KIFC1
Disease Area: cancer
Date Deposited: Sep 26 2007

[?]

Name: Plasmodium falciparum pyrroline carboxylate reductase
PDB Code: 2RCY
Target Class: Malaria
Target: Pf-P5CR
Disease Area: parasitic disease
Date Deposited: Sep 20 2007

[?]

Name: Human StAR-related lipid transfer protein 5
PDB Code: 2R55
Target Class: Lipid signalling
Target: STARD5
Disease Area: cancer
Date Deposited: Sep 03 2007

[?]

Name: Human membrane associated guanylate kinase, WW and PDZ domain containing 1 (9th domain)
PDB Code: 2R4H
Target Class: Linkers
Target: MAGI1
Disease Area: neurobiology
Date Deposited: Aug 31 2007

[?]

Name: Human PTK9L protein tyrosine kinase 9-like (1st. cofilin domain)
PDB Code: 2VAC
Target Class: Protein Kinase
Target: PTK9L (1st. cofilin domain)
Disease Area:
Date Deposited: Aug 30 2007

[?]

Name: Human suppressor of variegation 3-9 homolog 2 methyltransferase domain
PDB Code: 2R3A
Target Class: Transferases
Target: SUV39H2
Disease Area: cancer
Date Deposited: Aug 29 2007

[?]

Name: Human glutathione peroxidase 3
PDB Code: 2R37
Target Class: Oxidoreductases
Target: GPX3
Disease Area: metabolism, cancer, chromatin and epigenetics
Date Deposited: Aug 29 2007

[?]

Name: Human aminoimidazole ribonucleotide synthetase, AIRS domain
PDB Code: 2V9Y
Target Class: Nucleotide metabolism
Target: GART
Disease Area: cancer
Date Deposited: Aug 28 2007

[?]

Name: Human plexin B1 effector domain
PDB Code: 2R2O
Target Class: GTPases
Target: PLXNB1
Disease Area: cancer
Date Deposited: Aug 27 2007

[?]

Name: Human ephrin receptor EphA5
PDB Code: 2R2P
Target Class: Protein Kinase
Target: EPHA5
Disease Area: cancer, signalling
Date Deposited: Aug 27 2007

[?]

Name: Human GABA(A) receptor-associated protein like 1
PDB Code: 2R2Q
Target Class: ubiquitin family
Target: GABARAPL1
Disease Area:
Date Deposited: Aug 26 2007

[?]

Name: human p53-associated parkin-like cytoplasmic protein - CPH domain (NMR)
PDB Code: 2JUF
Target Class: ubiquitin family
Target: PARC
Disease Area: cancer
Date Deposited: Aug 23 2007

[?]

Name: Plasmodium falciparum ubiquitin-conjugating enzyme, putative
PDB Code: 2R0J
Target Class: Malaria
Target: Pf-UBC13
Disease Area: parasitic disease
Date Deposited: Aug 20 2007

[?]

Name: Human Paraplegin, AAA domain in complex with ADP
PDB Code: 2QZ4
Target Class: ATPases
Target: SPG7
Disease Area: neurobiology
Date Deposited: Aug 16 2007

[?]

Name: Human natrium-phosphate cotransporter IIa C-terminal-associated protein 2
PDB Code: 2V90
Target Class: Linkers
Target: PDZD3
Disease Area: signalling
Date Deposited: Aug 16 2007

[?]

Name: Plasmodium falciparum nucleolar GTP-binding protein 1
PDB Code: 2QU8
Target Class: Malaria
Target: Pf-NOG1
Disease Area: parasitic disease
Date Deposited: Aug 03 2007

[?]

Name: Human calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma
PDB Code: 2V7O
Target Class: Protein Kinase
Target: CAMK2G
Disease Area: metabolism, cancer, signalling, neurobiology
Date Deposited: Jul 31 2007

[?]

Name: Human acyl-CoA thioesterase 7
PDB Code: 2QQ2
Target Class: Lipid signalling
Target: ACOT7
Disease Area: metabolism
Date Deposited: Jul 26 2007

[?]

Name: Human TBC1 domain family, member 14
PDB Code: 2QQ8
Target Class: GTPases
Target: TBC1D14
Disease Area:
Date Deposited: Jul 26 2007

[?]

Name: Human dehydrogenase/reductase (SDR family) member 1
PDB Code: 2QQ5
Target Class: Oxidoreductases
Target: DHRS1
Disease Area:
Date Deposited: Jul 26 2007

[?]

Name: Human PR domain-containing protein 2, methyltransferase domain
PDB Code: 2QPW
Target Class: Transferases
Target: PRDM2
Disease Area: cancer
Date Deposited: Jul 25 2007

[?]

Name: Toxoplasma gondii apicoplast-targeted acyl carrier protein
PDB Code: 2QNW
Target Class: Transferases
Target: Tg-ACP
Disease Area: parasitic disease
Date Deposited: Jul 20 2007

[?]

Name: Human Septin 2 in complex with GDP [Homo sapiens]
PDB Code: 2QNR
Target Class: GTPases
Target: SEPT2
Disease Area: cancer
Date Deposited: Jul 19 2007

[?]

Name: Human vaccinia related kinase 2
PDB Code: 2V62
Target Class: Protein Kinase
Target: VRK2
Disease Area: signalling
Date Deposited: Jul 13 2007

[?]

Name: Human ephrin receptor EphB4 precursor; hepatoma transmembrane kinase Homo sapiens
PDB Code: 2QKQ
Target Class: Protein Kinase
Target: EPHB4
Disease Area: cancer, signalling
Date Deposited: Jul 11 2007

[?]

Name: Cryptosporidium parvum cyclin-dependent kinase with indirubin 3
PDB Code: 2QKR
Target Class: Malaria
Target: Cp-CDK (cgd5_2510)
Disease Area: parasitic disease
Date Deposited: Jul 11 2007

[?]

Name: Human glycinamide ribonucleotide synthetase, GARS domain
PDB Code: 2QK4
Target Class: Nucleotide metabolism
Target: GART
Disease Area: cancer
Date Deposited: Jul 10 2007

[?]

Name: Human farnesyl diphosphate synthase (Thr210 to Ser mutatnt bound to risidronate)
PDB Code: 2QIS
Target Class: Miscellaneous
Target: FDPS
Disease Area: metabolism, cancer, signalling
Date Deposited: Jul 05 2007

[?]

Name: Human Cysteine Sulfinic Acid Decarboxylase in complex with PLP
PDB Code: 2JIS
Target Class: AA metabolic enzymes
Target: CSAD
Disease Area: cancer
Date Deposited: Jun 30 2007

[?]

Name: Human ubiquitin-conjugating enzyme E2Q
PDB Code: 2QGX
Target Class: ubiquitin family
Target: UBE2Q1
Disease Area: cancer
Date Deposited: Jun 29 2007

[?]

Name: Human vaccinia related kinase 3
PDB Code: 2JII
Target Class: Protein Kinase
Target: VRK3
Disease Area: signalling, neurobiology
Date Deposited: Jun 28 2007

[?]

Name: Human synaptojanin 2 binding protein
PDB Code: 2JIK
Target Class: Linkers
Target: SYNJ2BP
Disease Area: signalling
Date Deposited: Jun 28 2007

[?]

Name: Human synaptojanin 2 binding protein
PDB Code: 2JIN
Target Class: Linkers
Target: SYNJ2BP
Disease Area: signalling
Date Deposited: Jun 28 2007

[?]

Name: Human UDP-glucose dehydrogenase (in complex with product)
PDB Code: 2QG4
Target Class: Oxidoreductases
Target: UGDH
Disease Area: metabolism, cancer, signalling, neurobiology
Date Deposited: Jun 28 2007

[?]

Name: Cryptosporidium parvum calcium dependent protein kinase
PDB Code: 2QG5
Target Class: Malaria
Target: Cp-CDPK (cgd7_1840)
Disease Area: parasitic disease
Date Deposited: Jun 28 2007

[?]

Name: Plasmodium vivax ethanolamine kinase
PDB Code: 2QG7
Target Class: Malaria
Target: Pv-EK
Disease Area: parasitic disease
Date Deposited: Jun 28 2007

[?]

Name: Human protein tyrosine phosphatase, receptor type, N polypeptide 2
PDB Code: 2QEP
Target Class: Phosphatases
Target: PTPRN2
Disease Area: neurobiology, signalling, metabolism
Date Deposited: Jun 27 2007

[?]

Name: Human calpain 7 C2 domain
PDB Code: 2QFE
Target Class: Proteases
Target: CAPN7
Disease Area: neurobiology
Date Deposited: Jun 27 2007

[?]

Name: Human TBC1 domain family, member 22A [Homo sapiens]
PDB Code: 2QFZ
Target Class: GTPases
Target: TBC1D22A
Disease Area: signalling
Date Deposited: Jun 27 2007

[?]

Name: Human Adenylosuccinate synthetase isozyme 2
PDB Code: 2V40
Target Class: Nucleotide metabolism
Target: ADSS2
Disease Area: cancer, drug metabolism and toxicology
Date Deposited: Jun 26 2007

[?]

Name: Human membrane associated guanylate kinase, WW and PDZ domain containing 1(7th domain)
PDB Code: 2Q9V
Target Class: Miscellaneous
Target: MAGI1
Disease Area:
Date Deposited: Jun 14 2007

[?]

Name: Human diphosphoinositol phosphohydrolase 1 in complex with IP6 and magnesiumfluoride
PDB Code: 2Q9P
Target Class: Phosphatases
Target: NUDT3
Disease Area: signalling
Date Deposited: Jun 13 2007

[?]

Name: Human orotidine 5\'-phosphate decarboxylase domain of uridine monophosphate synthetase (UMPS) in complex with UMP
PDB Code: 2V30
Target Class: Nucleotide metabolism
Target: UMPS
Disease Area: cancer
Date Deposited: Jun 10 2007

[?]

Name: Human SPRY domain-containing SOCS box protein SSB-4
PDB Code: 2V24
Target Class: SOCS-box-containing
Target: SPSB4
Disease Area:
Date Deposited: May 31 2007

[?]

Name: Human UDP-glucose dehydrogenase
PDB Code: 2Q3E
Target Class: Oxidoreductases
Target: UGDH
Disease Area: drug metabolism and toxicology, metabolism, neurobiology, signalling, cancer
Date Deposited: May 30 2007

[?]

Name: Human enigma protein [isoform 1]
PDB Code: 2Q3G
Target Class: Miscellaneous
Target: PDLIM7
Disease Area: metabolism, signalling
Date Deposited: May 30 2007

[?]

Name: Human ras homolog gene family, member U
PDB Code: 2Q3H
Target Class: GTPases
Target: RHOU
Disease Area: signalling, cancer
Date Deposited: May 30 2007

[?]

Name: Human PDZ and LIM domain 4
PDB Code: 2V1W
Target Class: Miscellaneous
Target: PDLIM4
Disease Area: neurobiology, cancer, signalling
Date Deposited: May 30 2007

[?]

Name: Human RecQ protein-like [isoform 1; tv1]
PDB Code: 2V1X
Target Class: DEAD
Target: RECQL
Disease Area: cancer
Date Deposited: May 30 2007

[?]

Name: Human selenoprotein S
PDB Code: 2Q2F
Target Class: Diabetes
Target: SELS
Disease Area: signalling
Date Deposited: May 28 2007

[?]

Name: Human Ras-related GTP binding D [Homo sapiens]
PDB Code: 2Q3F
Target Class: GTPases
Target: RRAGD
Disease Area: cancer
Date Deposited: May 27 2007

[?]

Name: Human hypothetical protein MGC2408
PDB Code: 2PXX
Target Class: Transferases
Target: MGC2408
Disease Area:
Date Deposited: May 14 2007

[?]

Name: human START domain containing protein 13
PDB Code: 2PSO
Target Class: Lipid signalling
Target: STARD13
Disease Area: cancer
Date Deposited: May 07 2007

[?]

Name: human Poly [ADP-ribose] polymerase 12
PDB Code: 2PQF
Target Class: Poly ADP-ribose polymerase
Target: PARP12
Disease Area: cancer
Date Deposited: May 02 2007

[?]

Name: human L3MBTL
PDB Code: 2PQW
Target Class: Methyl-lysine readers
Target: L3MBTL
Disease Area: cancer, chromatin and epigenetics
Date Deposited: May 02 2007

[?]

Name: Human testis and skeletal muscle-specific dual specificity phosphatase [isoform 6]
PDB Code: 2PQ5
Target Class: Phosphatases
Target: DUSP13
Disease Area: signalling
Date Deposited: May 01 2007

[?]

Name: Human gigaxonin
PDB Code: 2PPI
Target Class: BTB-Kelch
Target: GAN
Disease Area: neurobiology
Date Deposited: Apr 30 2007

[?]

Name: human pancreatic lipase-related protein 1
PDB Code: 2PPL
Target Class: Miscellaneous
Target: PNLIPRP1
Disease Area: metabolism
Date Deposited: Apr 30 2007

[?]

Name: Human protein kinase C gamma, C2 domain
PDB Code: 2UZP
Target Class: Protein Kinase
Target: PRKCG, C2 domain
Disease Area: neurobiology, cancer, signalling
Date Deposited: Apr 30 2007

[?]

Name: Human PDZ and LIM domain 5
PDB Code: 2UZC
Target Class: Miscellaneous
Target: PDLIM5
Disease Area: signalling, neurobiology, cancer
Date Deposited: Apr 27 2007

[?]

Name: Cp-CyPJ - Cryptosporidium parvum cyclophilin J
PDB Code: 2POE
Target Class: Malaria
Target: Cp-CyPJ (cgd2_1660)
Disease Area: parasitic disease
Date Deposited: Apr 26 2007

[?]

Name: human guanine deaminase
PDB Code: 2UZ9
Target Class: Nucleotide metabolism
Target: GUAD
Disease Area: signalling
Date Deposited: Apr 26 2007

[?]

Name: human isopentenyl-diphosphate delta isomerase 2
PDB Code: 2PNY
Target Class: Diabetes
Target: IDI2
Disease Area: metabolism
Date Deposited: Apr 25 2007

[?]

Name: Human peroxiredoxin 4 (thioredoxin peroxidase)
PDB Code: 2PN8
Target Class: Oxidoreductases
Target: PRDX4
Disease Area: cancer, metabolism
Date Deposited: Apr 24 2007

[?]

Name: human KRAS
PDB Code: 3GFT
Target Class: GTPases
Target: KRASB
Disease Area: signalling, cancer
Date Deposited: Apr 23 2007

[?]

Name: human RASEF calcium binding domain
PDB Code: 2PMY
Target Class: GTPases
Target: RASEF
Disease Area: signalling
Date Deposited: Apr 23 2007

[?]

Name: Plasmodium falciparum ribosomal RNA methyltransferase in complex with SAM
PDB Code: 2PLW
Target Class: Malaria
Target: Pf-FtsJ
Disease Area: parasitic disease
Date Deposited: Apr 20 2007

[?]

Name: human DEAD-box RNA Helicase DDX10, DEAD domain
PDB Code: 2PL3
Target Class: DExD-DExH RNA helicases
Target: DDX10
Disease Area: cancer
Date Deposited: Apr 19 2007

[?]

Name: Human glycerol 3 phosphate dehydrogenase like enzyme
PDB Code: 2PLA
Target Class: Oxidoreductases
Target: KIAA0089
Disease Area: metabolism
Date Deposited: Apr 19 2007

[?]

Name: Human PDZ and LIM domain 1 (elfin)
PDB Code: 2PKT
Target Class: Linkers
Target: PDLIM1
Disease Area: cancer
Date Deposited: Apr 18 2007

[?]

Name: human N-acetyltransferase 2 (arylamine N-acetyltransferase)
PDB Code: 2PFR
Target Class: Transferases
Target: NAT2
Disease Area: metabolism, drug metabolism and toxicology, cancer
Date Deposited: Apr 04 2007

[?]

Name: Cryptosporidium parvum conserved protein of unknown function
PDB Code: 2PD0
Target Class: Malaria
Target: cgd2_2020
Disease Area: parasitic disease
Date Deposited: Mar 31 2007

[?]

Name: Human hydroxysteroid (17-beta) dehydrogenase 8
PDB Code: 2PD6
Target Class: Oxidoreductases
Target: HSD17B8
Disease Area: cancer, signalling
Date Deposited: Mar 31 2007

[?]

Name: human FK506-binding protein 2 [Homo sapiens]
PDB Code: 2PBC
Target Class: isomerases
Target: FKBP2
Disease Area: signalling
Date Deposited: Mar 28 2007

[?]

Name: Plasmodium falciparum protein-L-isoaspartate O-methyltransferase beta-aspartate methyltransferase, putative
PDB Code: 2PBF
Target Class: Malaria
Target: Pf-PCMT
Disease Area: parasitic disease
Date Deposited: Mar 28 2007

[?]

Name: Human PDZ and LIM domain 2 [isoform 2]
PDB Code: 2PA1
Target Class: Linkers
Target: PDLIM2
Disease Area: cancer
Date Deposited: Mar 27 2007

[?]

Name: Human protein tyrosine phosphatase, non-receptor type 9
PDB Code: 2PA5
Target Class: Phosphatases
Target: PTPN9
Disease Area: metabolism, cancer, signalling
Date Deposited: Mar 27 2007

[?]

Name: Human calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma, association domain
PDB Code: 2UX0
Target Class: Protein Kinase
Target: CAMK2G
Disease Area: neurobiology, cancer, signalling, metabolism
Date Deposited: Mar 26 2007

[?]

Name: Human 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
PDB Code: 2P8U
Target Class: Oxidoreductases
Target: HMGCS1
Disease Area: metabolism
Date Deposited: Mar 23 2007

[?]

Name: Human DEAD-box RNA Helicase DDX41, Helicase domain
PDB Code: 2P6N
Target Class: DExD-DExH RNA helicases
Target: DDX41
Disease Area:
Date Deposited: Mar 19 2007

[?]

Name: human protein tyrosine phosphatase, non-receptor type 22 (lymphoid) [isoform 1]
PDB Code: 2P6X
Target Class: Phosphatases
Target: PTPN22
Disease Area: metabolism, cancer, signalling
Date Deposited: Mar 19 2007

[?]

Name: human RAS and EF hand domain containing [Homo sapiens]
PDB Code: 2P5S
Target Class: GTPases
Target: RASEF
Disease Area: signalling
Date Deposited: Mar 16 2007

[?]

Name: Plasmodium vivax ClpB chaperone - first nucleotide binding domain
PDB Code: 2P65
Target Class: Malaria
Target: Pv-ClpB-NBD1
Disease Area: parasitic disease
Date Deposited: Mar 16 2007

[?]

Name: Human zinc finger protein 289, ID1 regulated
PDB Code: 2P57
Target Class: GTPases
Target: ZNF289
Disease Area: signalling
Date Deposited: Mar 14 2007

[?]

Name: Human Uridine-Cytidine Kinase 1 in complex with ADP
PDB Code: 2UVQ
Target Class: Nucleotide metabolism
Target: UCK1
Disease Area: cancer
Date Deposited: Mar 13 2007

[?]

Name: glutathione peroxidase 7
PDB Code: 2P31
Target Class: Oxidoreductases
Target: GPX7
Disease Area: cancer, metabolism
Date Deposited: Mar 08 2007

[?]

Name: Human baculoviral inhibitor of apoptosis repeat containing protein 3 (BIRC3), BIR3 domain
PDB Code: 2UVL
Target Class: Apoptosis
Target: BIRC3
Disease Area: cancer
Date Deposited: Mar 08 2007

[?]

Name: Human histone acetyltransferase 1
PDB Code: 2P0W
Target Class: Transferases
Target: HAT1
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Mar 01 2007

[?]

Name: Human short/ branched chain acyl CoA dehydrogenase
PDB Code: 2JIF
Target Class: Oxidoreductases
Target: ACADSB
Disease Area: metabolism
Date Deposited: Feb 28 2007

[?]

Name: Human synapsin III in complex with AMPPNP
PDB Code: 2P0A
Target Class: Vesicle Transport
Target: SYN3
Disease Area: neurobiology
Date Deposited: Feb 28 2007

[?]

Name: Mer - human c-mer proto-oncogene tyrosine kinase
PDB Code: 2P0C
Target Class: Protein Kinase
Target: MERTK
Disease Area: cancer, signalling
Date Deposited: Feb 28 2007

[?]

Name: Human nicotiamide ribose kinase 1 in complex with tiazofurin
PDB Code: 2P0E
Target Class: Non-protein Kinase
Target: NRK1
Disease Area: metabolism, drug metabolism and toxicology
Date Deposited: Feb 28 2007

[?]

Name: Sex comb on midleg homolog 1
PDB Code: 2P0K
Target Class: Methyl-lysine readers
Target: SCMH1
Disease Area: chromatin and epigenetics
Date Deposited: Feb 28 2007

[?]

Name: Human solute carrier family 9 isoform 3 regulator 1 (SLC9A3R1) - 2nd PDZ domain
PDB Code: 2OZF
Target Class: Linkers
Target: NHERF-1(2nd PDZ domain)
Disease Area: cancer
Date Deposited: Feb 26 2007

[?]

Name: Human phosphoribosylpyrophosphate synthetase - associated protein 41 (pap41)
PDB Code: 2JI4
Target Class: Nucleotide metabolism
Target: PRPSAP2
Disease Area: neurobiology, cancer, signalling
Date Deposited: Feb 25 2007

[?]

Name: Human DEAD-box RNA helicase DDX20, DEAD domain in complex with ADP
PDB Code: 2OXC
Target Class: DExD-DExH RNA helicases
Target: DDX20
Disease Area: neurobiology
Date Deposited: Feb 20 2007

[?]

Name: pancreatic lipase-related protein 2
PDB Code: 2OXE
Target Class: Miscellaneous
Target: LIPS
Disease Area: metabolism
Date Deposited: Feb 20 2007

[?]

Name: Human jumonji domain containing 2A in complex with dimethylated H3K9 peptide
PDB Code: 2OX0
Target Class: Oxidoreductases
Target: JMJD2A + H3K9(me2) peptide
Disease Area: chromatin and epigenetics, cancer
Date Deposited: Feb 19 2007

[?]

Name: Human Uridine monophosphate synthetase - Orotidine-5
PDB Code: 2JGY
Target Class: Nucleotide metabolism
Target: UMPS
Disease Area: cancer
Date Deposited: Feb 16 2007

[?]

Name: Cryptosporidium parvum ADP-ribosylation factor GTPase-activating protein
PDB Code: 2OWA
Target Class: Malaria
Target: Cp-ARFGAP
Disease Area: parasitic disease
Date Deposited: Feb 15 2007

[?]

Name: Human GTPase activating protein
PDB Code: 2OVJ
Target Class: GTPases
Target: RACGAP1
Disease Area: cancer, signalling
Date Deposited: Feb 14 2007

[?]

Name: Human bromodomain containing protein 4 - domain 2
PDB Code: 2OUO
Target Class: Bromodomain
Target: BRD4 domain 2
Disease Area: signalling, chromatin and epigenetics, cancer
Date Deposited: Feb 12 2007

[?]

Name: Human ras-related C3 botulinum toxin substrate 3 (GTPase Rac3) in complex with human p21(CDKN1A) activated kinase 4
PDB Code: 2OV2
Target Class: GTPases
Target: RAC3 + PAK4
Disease Area: neurobiology, signalling, cancer
Date Deposited: Feb 12 2007

[?]

Name: Human HIV-1 Tat interactive protein, 60kDa isoform 2
PDB Code: 2OU2
Target Class: Transferases
Target: HTATIP
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Feb 09 2007

[?]

Name: Human jumonji domain containing 2A in complex with monomethylated H3K9 peptide
PDB Code: 2OT7
Target Class: Oxidoreductases
Target: JMJD2A + H3K9(me1) peptide
Disease Area: cancer, chromatin and epigenetics
Date Deposited: Feb 07 2007

[?]

Name: Human bromodomain containing protein 4 - domain 1
PDB Code: 2OSS
Target Class: Bromodomain
Target: BRD4 domain 1
Disease Area: cancer, signalling, chromatin and epigenetics
Date Deposited: Feb 06 2007

[?]

Name: Human jumonji domain containing 2A in complex with trimethylated H3K36 peptide
PDB Code: 2OS2
Target Class: Oxidoreductases
Target: JMJD2A + H3K36(me3) peptide
Disease Area: chromatin and epigenetics, cancer
Date Deposited: Feb 05 2007

[?]

Name: Human chimerin 1 Rho-GAP domain
PDB Code: 2OSA
Target Class: GTPases
Target: CHN1
Disease Area: neurobiology
Date Deposited: Feb 05 2007

[?]

Name: Human cytosolic fatty acid synthase - malonyl/acetyl-ACP transferase domain in complex with Malonyl-CoA
PDB Code: 2JFK
Target Class: Oxidoreductases
Target: FAS transferase domain + CoA
Disease Area: metabolism, cancer
Date Deposited: Feb 02 2007

[?]

Name: Human regulator of G-protein signalling 14 (NMR)
PDB Code: 2JNU
Target Class: G-Protein Regulators
Target: RGS14
Disease Area: signalling
Date Deposited: Feb 02 2007

[?]

Name: Human cytosolic fatty acid synthase
PDB Code: 2JFD
Target Class: Oxidoreductases
Target: FAS
Disease Area: cancer, metabolism
Date Deposited: Jan 31 2007

[?]

Name: Human jumonji domain containing 2A in complex with trimethylated H3K9 peptide
PDB Code: 2OQ6
Target Class: Oxidoreductases
Target: JMJD2A + H3K9(me3) peptide
Disease Area: chromatin and epigenetics, cancer
Date Deposited: Jan 31 2007

[?]

Name: Human jumonji domain containing 2A in complex with Ni and N-oxalylglycine
PDB Code: 2OQ7
Target Class: Oxidoreductases
Target: JMJD2A + Ni and N-oxalylglycine
Disease Area: chromatin and epigenetics, cancer
Date Deposited: Jan 31 2007

[?]

Name: Cryptosporidium parvum translation initiation factor 1A
PDB Code: 2OQK
Target Class: Malaria
Target: Cp-eIF-1A
Disease Area: parasitic disease
Date Deposited: Jan 31 2007

[?]

Name: Human phytanoyl-CoA dioxygenase domain containing 1
PDB Code: 2OPW
Target Class: Oxidoreductases
Target: PHYD1
Disease Area: metabolism
Date Deposited: Jan 30 2007

[?]

Name: Human Protein Tyrosine Phosphatase Receptor T
PDB Code: 2OOQ
Target Class: Phosphatases
Target: PTPRT
Disease Area: cancer, signalling, neurobiology
Date Deposited: Jan 26 2007

[?]

Name: Human bromodomain containing protein 3 - domain 2
PDB Code: 2OO1
Target Class: Bromodomain
Target: BRD3 domain 2
Disease Area: cancer, signalling
Date Deposited: Jan 25 2007

[?]

Name: Human ubiquitin-protein ligase NEDD4-like catalytic domain
PDB Code: 2ONI
Target Class: ubiquitin family
Target: NEDD4L
Disease Area: signalling, neurobiology
Date Deposited: Jan 24 2007

[?]

Name: Plasmodium falciparum ubiquitin conjugating enzyme - putative homologue to human UBE2H
PDB Code: 2ONU
Target Class: Malaria
Target: Pf-UBE2H
Disease Area: parasitic disease
Date Deposited: Jan 24 2007

[?]

Name: Human C terminal binding protein 2
PDB Code: 2OME
Target Class: Oxidoreductases
Target: CTBP2
Disease Area: metabolism
Date Deposited: Jan 22 2007

[?]

Name: Human cytochrome P450, family 2, R1 in complex with vitamin D3
PDB Code: 2OJD
Target Class: Miscellaneous
Target: CYP2R1
Disease Area: metabolism
Date Deposited: Jan 19 2007

[?]

Name: Human HIV-1 Rev binding protein
PDB Code: 2OLM
Target Class: GTPases
Target: HRB
Disease Area: cancer, signalling
Date Deposited: Jan 19 2007

[?]

Name: Human Uridine-Cytidine Kinase 1
PDB Code: 2JEO
Target Class: Nucleotide metabolism
Target: UCK1
Disease Area: cancer
Date Deposited: Jan 18 2007

[?]

Name: Human Glutamine Synthetase
PDB Code: 2OJW
Target Class: AA metabolic enzymes
Target: GS
Disease Area: neurobiology, metabolism
Date Deposited: Jan 15 2007

[?]

Name: Human RAB25 - member of RAS oncogene family
PDB Code: 2OIL
Target Class: GTPases
Target: RAB25
Disease Area: signalling
Date Deposited: Jan 11 2007

[?]

Name: Human BCL2 antagonist/killer 1
PDB Code: 2JCN
Target Class: Apoptosis
Target: BAK1
Disease Area: cancer, neurobiology
Date Deposited: Dec 27 2006

[?]

Name: Human Cytosolic 5'-Nuclotidase II in complex with Beryllium Trifluoride
PDB Code: 2JCM
Target Class: Phosphatases
Target: NT5C2
Disease Area: metabolism, cancer
Date Deposited: Dec 27 2006

[?]

Name: Human Inositol 1,3,4-trisphosphate 5/6-kinase
PDB Code: 2ODT
Target Class: Phosphoinosotide dependent signalling
Target: ITPK1
Disease Area: signalling
Date Deposited: Dec 26 2006

[?]

Name: Human Cell Division Control protein 42 in complex with human p21 activated kinase 6
PDB Code: 2ODB
Target Class: Protein Kinase
Target: CDC42 + PAK6
Disease Area: signalling, cancer
Date Deposited: Dec 22 2006

[?]

Name: Human regulator of G-protein signalling 8 in complex with Galphai3
PDB Code: 2ODE
Target Class: G-Protein Regulators
Target: RGS8 + Galphai3
Disease Area: neurobiology, signalling, cancer, metabolism
Date Deposited: Dec 22 2006

[?]

Name: Human solute carrier family 9 isoform 3 regulator 2 (SLC9A3R2) - 1st PDZ domain
PDB Code: 2OCS
Target Class: Linkers
Target: NHERF-2 (1st PDZ domain)
Disease Area: signalling
Date Deposited: Dec 21 2006

[?]

Name: Human Cytosolic 5'-Nuclotidase II in complex with Adenosine
PDB Code: 2JC9
Target Class: Phosphatases
Target: NT5C2
Disease Area: cancer, metabolism
Date Deposited: Dec 21 2006

[?]

Name: Human Ca2+/calmodulin-dependent protein kinase I-delta
PDB Code: 2JC6
Target Class: Protein Kinase
Target: CAMK1D
Disease Area: signalling
Date Deposited: Dec 20 2006

[?]

Name: Human methionine adenosyltransferase I
PDB Code: 2OBV
Target Class: Oxidoreductases
Target: MAT1
Disease Area: metabolism, cancer
Date Deposited: Dec 20 2006

[?]

Name: Human Tyrosine-protein phosphatase non-receptor type 18
PDB Code: 2OC3
Target Class: Phosphatases
Target: PTPN18
Disease Area: neurobiology, signalling, cancer
Date Deposited: Dec 20 2006

[?]

Name: Human Rab9 like protein
PDB Code: 2OCB
Target Class: GTPases
Target: RAB9B
Disease Area: neurobiology
Date Deposited: Dec 20 2006

[?]

Name: Human Mak3 homologue
PDB Code: 2OB0
Target Class: Transferases
Target: MAK3
Disease Area: chromatin and epigenetics
Date Deposited: Dec 18 2006

[?]

Name: Human ubiquitin conjugating enzyme CDC34
PDB Code: 2OB4
Target Class: ubiquitin family
Target: CDC34
Disease Area: signalling
Date Deposited: Dec 18 2006

[?]

Name: Human euchromatic histone-lysine N-methyltransferase 2
PDB Code: 2O8J
Target Class: Transferases
Target: EHMT2
Disease Area: chromatin and epigenetics
Date Deposited: Dec 12 2006

[?]

Name: Cryptosporidium parvum 14-3-3 protein
PDB Code: 2O8P
Target Class: Malaria
Target: Cp-14-3-3
Disease Area: parasitic disease
Date Deposited: Dec 12 2006

[?]

Name: Human Phosphoribosyl transferase domain containing 1
PDB Code: 2JBH
Target Class: Nucleotide metabolism
Target: PRTFDC1
Disease Area: metabolism
Date Deposited: Dec 07 2006

[?]

Name: Human Ras-related GTP-binding protein 4B
PDB Code: 2O52
Target Class: GTPases
Target: RAB4B
Disease Area: signalling
Date Deposited: Dec 05 2006

[?]

Name: Human multiple PDZ domain protein (1st domain)
PDB Code: 2O2T
Target Class: Linkers
Target: MPDZA (1st domain)
Disease Area: cancer, neurobiology
Date Deposited: Nov 30 2006

[?]

Name: Human MAP2K5 (MEK5)-MAP3K3 (MEKK3) Phox domain complex
PDB Code: 2O2V
Target Class: Protein Kinase
Target: MAP2K5 + MAP3K3
Disease Area: signalling, metabolism, cancer
Date Deposited: Nov 30 2006

[?]

Name: Human PP2A regulatory subunit B56g
PDB Code: 2JAK
Target Class: Phosphatases
Target: PPP2R5C
Disease Area: signalling, cancer, neurobiology
Date Deposited: Nov 29 2006

[?]

Name: Human Ca2+/calmodulin-dependent protein kinase I-gamma
PDB Code: 2JAM
Target Class: Protein Kinase
Target: CAMK1G
Disease Area: neurobiology, signalling
Date Deposited: Nov 29 2006

[?]

Name: Plasmodium vivax ribonucleotide reductase R2 subunit
PDB Code: 2O1Z
Target Class: Malaria
Target: Pv-RNR-R2
Disease Area: parasitic disease
Date Deposited: Nov 29 2006

[?]

Name: Human UBCE2I-HIP2 protein-protein complex
PDB Code: 2O25
Target Class: ubiquitin family
Target: UBCE2I-HIP2
Disease Area: signalling
Date Deposited: Nov 29 2006

[?]

Name: Human hexokinase 2
PDB Code: 2NZT
Target Class: Non-protein Kinase
Target: HK2
Disease Area: cancer, metabolism
Date Deposited: Nov 26 2006

[?]

Name: Human cell division protein FtsJ homolog 2 isoform b
PDB Code: 2NYU
Target Class: Transferases
Target: FTSJ2
Disease Area:
Date Deposited: Nov 24 2006

[?]

Name: Human Hydroxyacid Oxidase 1
PDB Code: 2NZL
Target Class: Oxidoreductases
Target: HAO1
Disease Area: metabolism
Date Deposited: Nov 24 2006

[?]

Name: Human RAS-like GTP-binding protein REM1 in complex with GDP
PDB Code: 2NZJ
Target Class: GTPases
Target: REM1
Disease Area: signalling, cancer
Date Deposited: Nov 23 2006

[?]

Name: Human Argininosuccinate synthase
PDB Code: 2NZ2
Target Class: AA metabolic enzymes
Target: ASS
Disease Area: metabolism
Date Deposited: Nov 22 2006

[?]

Name: Human Tyrosine Receptor Phosphatase J - CS mutant
PDB Code: 2NZ6
Target Class: Phosphatases
Target: PTPRJ CS mutant
Disease Area: signalling, cancer
Date Deposited: Nov 22 2006

[?]

Name: Human bromodomain containing protein 3 - domain 1
PDB Code: 2NXB
Target Class: Bromodomain
Target: BRD3 domain 1
Disease Area: signalling, cancer
Date Deposited: Nov 17 2006

[?]

Name: Human SLK (Ste20-like kinase) in complex with K00606a
PDB Code: 2UV2
Target Class: Protein Kinase
Target: SLK + K00606a
Disease Area: signalling, cancer
Date Deposited: Nov 16 2006

[?]

Name: Human kinesin family member 9
PDB Code: 2NR8
Target Class: Miscellaneous
Target: KIF9
Disease Area: cancer
Date Deposited: Nov 01 2006

[?]

Name: Human p53 inducible oxidoreductase
PDB Code: 2J8Z
Target Class: Oxidoreductases
Target: TP53I3
Disease Area: cancer
Date Deposited: Oct 31 2006

[?]

Name: Human Death Associated Kinase 3
PDB Code: 2J90
Target Class: Protein Kinase
Target: DAPK3
Disease Area: cancer, signalling
Date Deposited: Oct 31 2006

[?]

Name: Human MAP2K5 (MEK5)-MAP3K2 (MEKK2) Phox domain complex
PDB Code: 2NPT
Target Class: Protein Kinase
Target: MAP2K5 + MAP3K2
Disease Area: cancer, signalling, neurobiology
Date Deposited: Oct 30 2006

[?]

Name: Human calpain 8
PDB Code: 2NQA
Target Class: Proteases
Target: CAPN8
Disease Area: signalling, cancer
Date Deposited: Oct 30 2006

[?]

Name: Human cleavage and polyadenylation specificity factor 5 in complex with a sulphate ion
PDB Code: 2J8Q
Target Class: Nucleotide metabolism
Target: CPSF5
Disease Area: metabolism
Date Deposited: Oct 27 2006

[?]

Name: Cryptosporidium parvum 14-3-3 protein epsilon in complex with phosphorylated peptide
PDB Code: 2NPM
Target Class: Malaria
Target: Cp-YWHAE
Disease Area: parasitic disease
Date Deposited: Oct 27 2006

[?]

Name: Human Cystathionine gamma lyase
PDB Code: 2NMP
Target Class: AA metabolic enzymes
Target: CTH
Disease Area: metabolism
Date Deposited: Oct 23 2006

[?]

Name: Human Protein Tyrosine Phosphatase Receptor G (PTPRG) D1-D2 domain
PDB Code: 2NLK
Target Class: Phosphatases
Target: PTPRG
Disease Area: cancer, signalling, neurobiology
Date Deposited: Oct 20 2006

[?]

Name: Human Adenylosuccinate Lyase in complex with AMP
PDB Code: 2J91
Target Class: Nucleotide metabolism
Target: ADSL
Disease Area: cancer, neurobiology
Date Deposited: Oct 19 2006

[?]

Name: Human Serine Threonine kinase 10 (STK10, LOK)
PDB Code: 2J7T
Target Class: Protein Kinase
Target: STK10
Disease Area: signalling, cancer
Date Deposited: Oct 17 2006

[?]

Name: Human stromal membrane-associated protein 1-like
PDB Code: 2IQJ
Target Class: GTPases
Target: SMAP1L
Disease Area: signalling
Date Deposited: Oct 13 2006

[?]

Name: Human fibrillarin
PDB Code: 2IPX
Target Class: Transferases
Target: FBL
Disease Area: metabolism
Date Deposited: Oct 12 2006

[?]

Name: Human regulator of G-protein signalling 16 in complex with the activated state of Galpha1
PDB Code: 2IK8
Target Class: G-Protein Regulators
Target: RGS16 + Galpha1
Disease Area: metabolism, signalling, neurobiology
Date Deposited: Oct 02 2006

[?]

Name: Human RAB12 like protein
PDB Code: 2IL1
Target Class: GTPases
Target: LOC201475
Disease Area: signalling
Date Deposited: Oct 02 2006

[?]

Name: Cryptosporidium parvum 14-3-3 protein
PDB Code: 2IJP
Target Class: Malaria
Target: Cp-YWHAZ
Disease Area: parasitic disease
Date Deposited: Sep 30 2006

[?]

Name: Human aldehyde dehydrogenase 7A1
PDB Code: 2J6L
Target Class: Oxidoreductases
Target: ALDH7A1
Disease Area: neurobiology, metabolism
Date Deposited: Sep 29 2006

[?]

Name: Human nicotinamide N-methyltransferase
PDB Code: 2IIP
Target Class: Transferases
Target: NNMT
Disease Area: metabolism
Date Deposited: Sep 27 2006

[?]

Name: Human regulator of G-protein signalling 10 in complex with the activated state of Galphai3
PDB Code: 2IHB
Target Class: G-Protein Regulators
Target: RGS10 + Galphai3
Disease Area: neurobiology, metabolism, signalling
Date Deposited: Sep 26 2006

[?]

Name: Human BTB and CNC homology 1
PDB Code: 2IHC
Target Class: BTB-Kelch
Target: BACH1
Disease Area: cancer, signalling
Date Deposited: Sep 26 2006

[?]

Name: Human regulator of G-protein signalling 8
PDB Code: 2IHD
Target Class: G-Protein Regulators
Target: RGS8
Disease Area: signalling, neurobiology, cancer
Date Deposited: Sep 26 2006

[?]

Name: Human peroxisomal acetyl-CoA acyl transferase 1
PDB Code: 2IIK
Target Class: Oxidoreductases
Target: ACAA1
Disease Area: metabolism
Date Deposited: Sep 26 2006

[?]

Name: The TIR domain of human Toll-Like Receptor 10 (TLR10)
PDB Code: 2J67
Target Class: Signalling proteins
Target: TLR10
Disease Area: parasitic disease
Date Deposited: Sep 26 2006

[?]

Name: Human euchromatic histone methyltransferase 1
PDB Code: 2IGQ
Target Class: Transferases
Target: EHMT1
Disease Area: chromatin and epigenetics
Date Deposited: Sep 23 2006

[?]

Name: Human choline kinase beta
PDB Code: 2IG7
Target Class: Non-protein Kinase
Target: CHKB
Disease Area: metabolism
Date Deposited: Sep 22 2006

[?]

Name: Human ras-related C3 botulinum toxin substrate 3 (GTPase Rac3) in complex with GPPnhP
PDB Code: 2IC5
Target Class: GTPases
Target: RAC3 in complex with GPPnhP
Disease Area: signalling, neurobiology, cancer
Date Deposited: Sep 12 2006

[?]

Name: Human ubiquitin specific protease 2 in complex with Ubiquitin
PDB Code: 2IBI
Target Class: ubiquitin family
Target: USP2
Disease Area: signalling
Date Deposited: Sep 11 2006

[?]

Name: Human Aldehyde reductase like 6
PDB Code: 2IBN
Target Class: Oxidoreductases
Target: ALDRL6
Disease Area: signalling, metabolism
Date Deposited: Sep 11 2006

[?]

Name: Human SLK (Ste20-like kinase)
PDB Code: 2J51
Target Class: Protein Kinase
Target: SLK
Disease Area: cancer, signalling
Date Deposited: Sep 08 2006

[?]

Name: Human Hydroxyisobutyrate dehydrogenase in complex with cofactor
PDB Code: 2I9P
Target Class: Oxidoreductases
Target: HIBADH + cofactor
Disease Area: metabolism
Date Deposited: Sep 06 2006

[?]

Name: Human pantothnate kinase 1
PDB Code: 2I7N
Target Class: Non-protein Kinase
Target: PANK1
Disease Area: neurobiology, metabolism
Date Deposited: Aug 31 2006

[?]

Name: Human pantothnate kinase 3
PDB Code: 2I7P
Target Class: Non-protein Kinase
Target: PANK3
Disease Area: neurobiology, metabolism
Date Deposited: Aug 31 2006

[?]

Name: Human choline kinase alpha
PDB Code: 2I7Q
Target Class: Non-protein Kinase
Target: CHKA
Disease Area: cancer
Date Deposited: Aug 31 2006

[?]

Name: Plasmodium vivax 2-cys peroxiredoxin - reduced conformation
PDB Code: 2I81
Target Class: Malaria
Target: Pv-2cys-Prx
Disease Area: parasitic disease
Date Deposited: Aug 31 2006

[?]

Name: Human Tyrosine Phosphatase N4 (MEG-1), phosphatase domain
PDB Code: 2I75
Target Class: Phosphatases
Target: PTPN4
Disease Area: neurobiology, signalling
Date Deposited: Aug 30 2006

[?]

Name: Human calpain 13
PDB Code: 2I7A
Target Class: Proteases
Target: CAPN13
Disease Area: signalling
Date Deposited: Aug 30 2006

[?]

Name: Human MAP Kinase 6
PDB Code: 2I6L
Target Class: Protein Kinase
Target: MAPK6
Disease Area: cancer, signalling
Date Deposited: Aug 29 2006

[?]

Name: Human ubiquitin conjugating enzyme E2
PDB Code: 2I6T
Target Class: ubiquitin family
Target: UEV3
Disease Area: signalling
Date Deposited: Aug 29 2006

[?]

Name: Human regulator of G-protein signalling 10 (NMR)
PDB Code: 2I59
Target Class: G-Protein Regulators
Target: RGS10
Disease Area: signalling, neurobiology
Date Deposited: Aug 24 2006

[?]

Name: Human histone deacetylase 7A isoform a
PDB Code: 2NVR
Target Class: Miscellaneous
Target: HDAC7
Disease Area: chromatin and epigenetics
Date Deposited: Aug 24 2006

[?]

Name: Human glutathione peroxidase 5
PDB Code: 2I3Y
Target Class: Oxidoreductases
Target: GPX5
Disease Area: metabolism
Date Deposited: Aug 21 2006

[?]

Name: Human DEAD-box RNA helicase DDX3X
PDB Code: 2I4I
Target Class: DExD-DExH RNA helicases
Target: DDX3X
Disease Area: cancer
Date Deposited: Aug 21 2006

[?]

Name: Human Purine 5-prime-nucleotidase (NT5C2)
PDB Code: 2J2C
Target Class: Phosphatases
Target: NT5C2
Disease Area: metabolism, cancer
Date Deposited: Aug 16 2006

[?]

Name: Human Proviral Integration Site for MuLV (PIm1) in complex with LY333531
PDB Code: 2J2I
Target Class: Protein Kinase
Target: PIM1 in complex with LY333531
Disease Area: cancer, signalling
Date Deposited: Aug 16 2006

[?]

Name: First PDZ domain of the human discs, large homolog 3 protein
PDB Code: 2I1N
Target Class: Linkers
Target: DLG3 (1st PDZ domain)
Disease Area: signalling
Date Deposited: Aug 14 2006

[?]

Name: Human Ras homolog gene family, member D
PDB Code: 2J1L
Target Class: GTPases
Target: RHOD
Disease Area: signalling
Date Deposited: Aug 14 2006

[?]

Name: Human p21(CDKN1A) activated kinase 4
PDB Code: 2J0I
Target Class: Protein Kinase
Target: PAK4
Disease Area: cancer, neurobiology, signalling
Date Deposited: Aug 03 2006

[?]

Name: Human phosphohistidine phosphatase 1
PDB Code: 2HW4
Target Class: Phosphatases
Target: PHPT1
Disease Area: signalling
Date Deposited: Jul 31 2006

[?]

Name: Human Enoyl-coenzyme A (CoA) Hydratase Short Chain 1
PDB Code: 2HW5
Target Class: Oxidoreductases
Target: ECHS1
Disease Area: metabolism, cancer
Date Deposited: Jul 31 2006

[?]

Name: Human Pyrroline 5 Carboxylate Reductase
PDB Code: 2IZZ
Target Class: Oxidoreductases
Target: PYCR
Disease Area: cancer, metabolism
Date Deposited: Jul 31 2006

[?]

Name: Plasmodium vivax adenylosuccinate lyase
PDB Code: 2HVG
Target Class: Malaria
Target: Pv-ASL
Disease Area: parasitic disease
Date Deposited: Jul 28 2006

[?]

Name: Human RAB43 protein
PDB Code: 2HUP
Target Class: GTPases
Target: RAB43
Disease Area: signalling
Date Deposited: Jul 27 2006

[?]

Name: Human Casein Kinase I gamma 3 in complex with K00576: a di-substituted diaminothiazole scaffold
PDB Code: 2IZR
Target Class: Protein Kinase
Target: CSNK1G3 + K00576
Disease Area: cancer, signalling
Date Deposited: Jul 26 2006

[?]

Name: Human Casein Kinase I gamma 3 in complex with K00577: a di-substituted diaminothiazole scaffold
PDB Code: 2IZS
Target Class: Protein Kinase
Target: CSNK1G3 + K00577
Disease Area: cancer, signalling
Date Deposited: Jul 26 2006

[?]

Name: Human Casein Kinase I gamma 3 in complex with CGP74514A
PDB Code: 2IZT
Target Class: Protein Kinase
Target: CSNK1G3 + CGP74514A
Disease Area: cancer, signalling
Date Deposited: Jul 26 2006

[?]

Name: Human Casein Kinase I gamma 3 in complex with Purvalanol A
PDB Code: 2IZU
Target Class: Protein Kinase
Target: CSNK1G3 + K00227
Disease Area: cancer, signalling
Date Deposited: Jul 26 2006

[?]

Name: Human SOCS4-ElonginC-ElonginB complex
PDB Code: 2IZV
Target Class: SOCS-box-containing
Target: SOCS4-Elongin B/C
Disease Area: signalling
Date Deposited: Jul 26 2006

[?]

Name: Human Glutaredoxin 2 with iron-sulphur cluster
PDB Code: 2HT9
Target Class: Oxidoreductases
Target: GLRX2 + FeS
Disease Area: neurobiology, metabolism
Date Deposited: Jul 25 2006

[?]

Name: Human Carbonyl Reductase
PDB Code: 2HRB
Target Class: Oxidoreductases
Target: CBR3
Disease Area: neurobiology, cancer, metabolism, drug metabolism and toxicology
Date Deposited: Jul 20 2006

[?]

Name: Human ribonucleotide reductase, R2 subunit
PDB Code: 2UW2
Target Class: Nucleotide metabolism
Target: RRM2
Disease Area: cancer
Date Deposited: Jul 17 2006

[?]

Name: Human ketohexokinase
PDB Code: 2HLZ
Target Class: Non-protein Kinase
Target: KHK
Disease Area: metabolism
Date Deposited: Jul 10 2006

[?]

Name: Human multiple PDZ domain protein (3rd domain)
PDB Code: 2IWN
Target Class: Linkers
Target: MPDZ (3rd domain)
Disease Area: cancer, neurobiology
Date Deposited: Jul 03 2006

[?]

Name: Human multiple PDZ domain protein (12th domain)
PDB Code: 2IWO
Target Class: Linkers
Target: MPDZ (12th domain)
Disease Area: cancer, neurobiology
Date Deposited: Jul 03 2006

[?]

Name: Human multiple PDZ domain protein (12th domain), alt. crystal form
PDB Code: 2IWP
Target Class: Linkers
Target: MPDZ (12th domain), alt. crystal form
Disease Area: cancer, neurobiology
Date Deposited: Jul 03 2006

[?]

Name: Human multiple PDZ domain protein (7th domain), alt. crystal form
PDB Code: 2IWQ
Target Class: Linkers
Target: MPDZ (7th domain), alt. crystal form
Disease Area: cancer, neurobiology
Date Deposited: Jul 03 2006

[?]

Name: Human Centaurin Gamma 1 - GTPase Domain, alt. crystal form
PDB Code: 2IWR
Target Class: GTPases
Target: CENTG1, alt. crystal form
Disease Area: signalling, neurobiology, cancer
Date Deposited: Jul 03 2006

[?]

Name: Cryptosporidium parvum malate dehydrogenase with ADP ribose bound
PDB Code: 2HJR
Target Class: Malaria
Target: Cp-MDH
Disease Area: parasitic disease
Date Deposited: Jun 30 2006

[?]

structure gallery

624 structures for iSee collection