We are seeking a highly enthusiastic and dedicated Postdoctoral Research Scientist with membrane protein structural biology experience to develop the pipeline for membrane protein production for structural and functional studies for Professor Liz Carpenters group at the SGC. You will be involved in a range of projects involving proteins that have been shown to be mutated in neuropsychiatric disease, cancer and rare and metabolic disease. You will be joining a group of experienced membrane protein structural biologists who have solved the structures of eleven proteins involved in human disease. You will be responsible for running and developing the membrane protein production pipeline, producing proteins for structural studies, growing crystals for X-ray crystallography and preparing grids for structural studies, combined with biophysical and biochemical methods to study function.
To qualify for this post you would need a PhD (or equivalent) or be close to completing this qualification in a relevant area of protein science. You should have proven experience in: protein expression, purification, crystallisation and/or grid preparation using a variety of methods, preferably on membrane proteins. You will also have experience in using biophysical and biochemical methods to study protein function. You will have excellent presentation and written communication skills, and have a proven record in preparation of high quality research publications. You will be highly self-motivated, well-organized and flexible, with strong planning and problem solving skills, able to work independently and as part of a team, and to collaborate with colleagues and external collaborators.
This post is fixed-term until 30 June, 2020, in the first instance.
You will be required to upload a CV and supporting statement, which explains how you meet the selection criteria for the post.
Only applications received before 12.00 noon on 23 August 2018 will be considered. Interviews will be taking place in week commencing 3 September 2018.
The SGC as part of the Nuffield Department of Medicine is a family friendly department: http://www.ndm.ox.ac.uk/family-friendly