We have an opportunity for a Postdoctoral Scientist in the group of Dr Frank von Delft, jointly head of the Protein Crystallography group at the SGC and beamline I04-1 of Diamond synchrotron. The groups have partnered in a joint research project to establishing fragment screening by crystal structure as a routine and accessible experiment, and are collaborating on how this can directly predict chemical synthesis for novel ligands.
The Fragment Screening post will be responsible for performing complete fragment screening experiments on prioritized SGC targets, to support chemical biology of these targets. The methodology goal is to establish best-practice for the experiment, and ensure that the methods and infrastructures under development do lead to a routine process. Extensive experience in crystallisation and protein crystallography is essential.
This post requires a scientist that is able to drive research programs independently, work well in a team, is instinctively collaborative, and understands the importance of shared credit to drive science. A strong interest in developing methodology is essential, and an interest in programming is a distinct advantage. A PhD around protein crystallography (or equivalent training and experience), and a record of publishing scientific papers will be required.
Only applications received before 12.00 noon on Friday 5 October 2018 will be considered.
The SGC as part of the Nuffield Department of Medicine is a family friendly department: http://www.ndm.ox.ac.uk/family-friendly