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A public-private partnership that supports the discovery of new medicines through open access research.
Linkedin Share Button Share on Facebook Tweet Widget Harnessing Protein Degradation for Drug Discovery March 4th 2019, Toronto, Canada Chestnut Residence & Conference Centre, 89 Chestnut St, Toronto, ON M5G 1R, Canada Workshop Edit tabsDetails Register Free Before Feb 14th 2019 Topics: Proteolysis Targeting Chimeras (PROTACs) Small molecule ligands for ubiquitin E3 Ligases Cellular modulation of protein levels with small molecules Supported by ChemNet NSERC CREATE Program ProgrammeConfirmed Speakers 09:00 - 09:40am: Ivan Dikic (Goethe-Universität, Frankfurt) Targeting conventional and non-conventional Ub ligases 09:40 - 10:10am: Frank Sicheri (Lunenfeld-Tanenbaum Institute, University of Toronto) Generating molecular probes to interrogate oncogenic kinase function 10:10 - 10:40am: Lindsey Ingerman James (University of North Carolina) Permeability: the missing link in PROTAC efficiency 10:40 - 11:00am: BREAK (Meeting room foyer) 11:00 - 11:30am: Stefan Knapp (Goethe-Universität, Frankfurt) Designing bi-functional small molecules 11:30 - 12:00pm: Jian Jin (Icahn School of Medicine at Mount Sinai, New York) Novel Degraders Targeting Oncogenic Proteins 12:00 - 12:30pm: Harald Weinstabl (Boehringer Ingelheim, Vienna) Structure-based PROTAC design demonstrates BAF complex ATPase vulnerabilities in cancer 12:30 - 01:30pm: LUNCH (Meeting room foyer) 01:30 - 02:00pm: Danette Daniels (Promega Corporation, Madison) Monitoring dynamics of protein degradation and interactions in live cells 02:00 - 02:30pm: Killian Huber (University of Oxford) Title TBD 02:30 - 03:10pm: Daniel Nomura (University of California) Reimagining Druggability using Chemoproteomic Platforms LocationVenue Chestnut Residence 89 Chestnut St, Toronto, ON M5G 1R, Canada Register
Linkedin Share Button Share on Facebook Tweet Widget Harnessing Protein Degradation for Drug Discovery March 4th 2019, Toronto, Canada Chestnut Residence & Conference Centre, 89 Chestnut St, Toronto, ON M5G 1R, Canada Workshop Edit tabsDetails Register Free Before Feb 14th 2019 Topics: Proteolysis Targeting Chimeras (PROTACs) Small molecule ligands for ubiquitin E3 Ligases Cellular modulation of protein levels with small molecules Supported by ChemNet NSERC CREATE Program ProgrammeConfirmed Speakers 09:00 - 09:40am: Ivan Dikic (Goethe-Universität, Frankfurt) Targeting conventional and non-conventional Ub ligases 09:40 - 10:10am: Frank Sicheri (Lunenfeld-Tanenbaum Institute, University of Toronto) Generating molecular probes to interrogate oncogenic kinase function 10:10 - 10:40am: Lindsey Ingerman James (University of North Carolina) Permeability: the missing link in PROTAC efficiency 10:40 - 11:00am: BREAK (Meeting room foyer) 11:00 - 11:30am: Stefan Knapp (Goethe-Universität, Frankfurt) Designing bi-functional small molecules 11:30 - 12:00pm: Jian Jin (Icahn School of Medicine at Mount Sinai, New York) Novel Degraders Targeting Oncogenic Proteins 12:00 - 12:30pm: Harald Weinstabl (Boehringer Ingelheim, Vienna) Structure-based PROTAC design demonstrates BAF complex ATPase vulnerabilities in cancer 12:30 - 01:30pm: LUNCH (Meeting room foyer) 01:30 - 02:00pm: Danette Daniels (Promega Corporation, Madison) Monitoring dynamics of protein degradation and interactions in live cells 02:00 - 02:30pm: Killian Huber (University of Oxford) Title TBD 02:30 - 03:10pm: Daniel Nomura (University of California) Reimagining Druggability using Chemoproteomic Platforms LocationVenue Chestnut Residence 89 Chestnut St, Toronto, ON M5G 1R, Canada Register
