A collection of well-characterized chemical probes and related reagents for the study of methylation-mediated signaling.

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains

The SGC is a public-private partnership that supports the discovery of new medicines through open access research.

Created, discovered and shared by the SGC without restriction on use: innovation for everyone.

A Global network of multi-talented and multi-cultural team of cross-disciplinary scientists: all committed to accelerate drug discovery.

Informing and engaging to transform drug discovery into an inclusive endeavour.

Real and tangible innovation through continuing exploration of novel proteins of relevance to drug discovery.

During the COVID-19 pandemic, Structural Genomics Consortium is taking measures to prevent the spread of the disease.

Departments are instructed by the University’s Registrar to continue to work from home where possible, and manage the return to on site working, based on the University guidelines for risk assessments and work prioritisation.

This is to restrict contact between individuals as far as possible. The University remains open and operating as far as possible with the following restrictions -

  • No public access to the University
  • On-site activity permitted where it cannot be undertaken remotely, driven by safety, capacity and other factors such as schools reopening/other changes in government guidelines
  • Teaching and assessment are undertaken remotely where possible and, depending on government guidelines, gatherings of staff and students only permitted where essential for teaching and assessment to take place


Protect our community. Protect the vulnerable. Protect yourself.

covid-19 response

SGC Oxford

SGC Oxford seeks to generate high quality reagents to accelerate the discovery of new medicines and place them into the public domain without restriction. Using 3D structures of human proteins and the reagents generated as part of the structure determination process as well as the chemical probes identified, we work with organisations within Oxford, the UK and the rest of the world to further the understanding of the biological roles of these proteins. We have particular interests in human protein kinases, metabolism-associated proteins, integral membrane proteins and proteins associated with epigenetics.

Contact Us

Old Road Campus Research Building

TDI Building

The SGC Oxford laboratories, under the direction of Prof. Chas Bountra, are housed within the University's Old Road Campus located in Headington, Oxford. SGC Oxford is part of the Nuffield Department of Clinical Medicine and scientists at SGC Oxford are affiliated with several University Departments including the Kennedy Institute and the Botnar Research Centre, NDORMS. Contact details

Careers in Oxford

There are currently no open vacancies with the SGC Oxford. Please check back periodically for opportunities which may arise in any of our sites.
Green Impact

Green Impact is an environmental accreditation scheme that brings together staff and students across the University to play an active role in improving the sustainable practices of their office, building or department. At the end of the year – joined by the Vice-Chancellor – teams, students and management come together to celebrate the part they have played in creating a positive impact at the University. The SGC is part of the Green Impact team for Old Road Campus Research Building (ORCRB). In 2016, ORCRB achieved the Bronze Award, and is aiming for the Silver Award in 2017.

If you have any suggestions for how improving our environmental impact please contact orcrb.greenimpact@ndm.ox.ac.uk

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