TOronto Ubiquitin Club And Network (TOUCAN)

TOronto Ubiquitin Club And Network [TOUCAN]

TOUCAN is a Toronto-wide (bi-)monthly meeting of folks interested in all things Ubiquitin started in Feb. 2013. There are more than a dozen labs in Greater Toronto Area working in the field of ubiquitin and ubiquitin-like proteins.  We have complementary interests and technologies. TOUCAN aims to bring scientists together and to promote collaboration by sharing research progresss and knowledge. TOUCAN is proudly sponsored by SGC and UbpBio, a ubiquitin company based on Colorado. Please contact <yufeng.tong at > if you want to know more details or to be added to mail list for future event notice.


Upcoming Events:

Title: Structural Biology Of Mitochondrial Quality Control System Involved In Parkinson's Disease

Speaker:Professor Kalle Gehring, Department of Biochemistry, McGill University
Date &Time: Friday, July 24, 2015, 11:30am - 12:30 pm
Location: Princess Margaret Cancer Centre 7-605, 610 University Ave

Ubiqutin Research in Toronto

Toronto is a strong-hold of ubiquitin biology research,especially in structural biology of ubiquitin-related systems

Past Events:

Feb 20, 2015, Friday 2:30-3:30pm at MaRS Centre, TMDT 4-204

Chemistry and Biolog of Protein Ubiquitination in DNA Damage Response
by Invited speaker: Zhihao Zhuang from University of Delaware, on USP1 inhibitors.

Feburary 12, 2013, at Medical School Building, Rm. 2173, University of Toronto

Ubiquitin biology program in Structural Genomics Consortium - the phase 3, by Dr. Yufeng Tong, Structural Genomics Consortium

Pathogen E3 Ubiquitin ligases – the unwelcomed participants in host ubiquitination system, by Dr. Alexei Savchenko, Structural Proteomics in Toronto

April 2, 2013, at Medical School Building, Rm. 2173, University of Toronto

Ubiquitin Variants as Modulators of Enzymes in the Ubiquitin System
by Dr. Sachdev Sidhu from Donnelly Centre for Cellular and Biomolecular Research, University of Toronto

Identification of ubiquitin E2 interacting partners links Rad6 to new cellular functions
by Dr. Brian Raught from Department of Medical Biophysics, University of Toronto

April 30, 2013, at Best Auditorium Rm.114, University of Toronto

Topic: The E3 ubiquitin ligases RNF126 and Rabring7 regulate endosomal sorting of the Epidermal Growth Factor Receptor

Christopher J. Smith from Dr. Jane McGlade lab, University of Toronto

Topic: Rnf8 and Rnf168 E3 ligases: Guardians of genomic integrity

Dr. Marie-Ho Halabby from Dr. Razq Hakem Lab, Ontario Cancer Institute

June 11, 2013

Topic: USP7/HAUSP is a Regulator of UbE2E1/UBCH6

by Dr. Vivian Saridakis from York University

Topic: USP7 regulates UbE2E1/UBCH6 activity in the PRC1 complex and represses the p16 locus and growth inhibition

by Dr. Yi Sheng from York University

Aug. 12, 2013

Special TOUCAN talk by Dr. Jiemin Wong from East China Normal University at Shanghai

Topic: Regulation of DNA Methylation by UHRF family of proteins

Oct. 15, 2013

Topic: The multiple functions of USP7
Speaker: Dr. Lori Frappier from Department of Molecular Genetics at the University of Toronto 

Topic: Multivalent Structures of Cullin E3 Ligase Complexes
Speaker: Dr. Gil Privé from Department of Biochemistry at the University of Toronto

Nov. 12, 2013

Topic: 53BP1 is a reader of the DNA damage-induced H2A Lys15 ubiquitin mark, Speaker: Dr. Amelie Fradet Turcotte  from Daniel Durocher Lab

Topic: Role of Tyrosine phosphorylation of Nedd4 in regulation of its catalytic activity,  Speaker: Dr. Avinash Persaud from Daniela Rotin Lab

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