Click here to obtain this probe.
The SGC in collaboration with the Memorial Sloan Kettering Cancer Center has developed SKI-73, a chemical probe for PRMT4. SKI-73 is a prodrug of SKI-72, a potent and selective inhibitor of PRMT4 and is active in cells.
Data relating to the discovery of this probe is being prepared for publication. In the meantime, in order to facilitate research by the community we are making this compound available through this website