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International Structural Genomics Consortium Announces $48.9 Million in Additional Funding to Continue the Search for New Medicines

The international Structural Genomics Consortium (SGC) today announced $48.9 million in new funding has been attained

The Drug Discovery Unit at the University of Dundee identifies new N-myristoyltransferase inhibitors as leads to treat sleeping sickness

"Sleeping sickness", also known as human African trypanosomiasis, is responsible for approximately 30,000 deaths each year and 70 million people are at risk of infection, as estimated by the World Health Organization

Small molecule compound used to probe into the role of Mps1

Functional and localization experiments in mammalian cells have demonstrated that Mps1 is essential for the fidelity of the cell cycle and genomic stability.

Opening the gates for a new therapeutic opportunity in the fight against apicomplexan parasites

Apicomplexan parasites are a diverse group of protozoan parasites, several of which cause important human and animal diseases, such as malaria, cryptosporidiosis and toxoplasmosis

SGC joins European Union Framework Programme 7 grant on Affinomics.

The SGC has been awarded more than 0.5 M Euro as part of a joint EU FP7 -Health grant: 'Protein Binders for Characterisation of Human Proteome Function: Generation, Validation, Application "Affinomics", which encompasses 15 participant labs in eight different European countries for 5 years.

Structural Genomics Consortium releases 1000th protein structure.

The Structural Genomics Consortium (SGC), an international public-private partnership that aims to determine three dimensional structures of medically important proteins, announced today the release into the public domain of its 1000th high resolution protein structure.

Genetic and Structural Studies Highlight Novel Key Factors in Autoimmune Diseases

A research team led by scientists from Oxford University (including the Structural Genomics Consortium, the Botnar Research Centre, the Weatherall Institute of Molecular Medicine, the Wellcome Building for Molecular Physiology, and the australian Diamantina Institute in Brisbane), have successfully deciphered the molecular mechanism how an ER protease (ERAP1) functions in a key step in cellular immunity- the processing of peptide antigens that are presented to Major Histocompatibilty Complex 1 (MHC1) molecules.

Cerep to build epigenetics screening and profiling laboratory in Toronto

The Structural Genomic Consortium (SGC) announced  today  that  SGC and  Cerep, a worldleading biotechnology company, will enter into a collaboration to develop open access biochemical and cell-based  assays for the discovery of small molecule chemical probes and drug candidates on epigenetic targets. As part of the collaboration, Cerep will open a laboratory in Toronto from which it will offer its screening and profiling services.

Wellcome Trust 75 Years Celebration

As part of the celebrations, Wellcome Trust researchers from the SGC, the Department of Zoology, the University Museum of Natural History and the Museum of History of Science at the University of Oxford present a stimulating series of events.

Unique public-private research partnership leads world in determining 3-d structure of proteins related to human disease

Structural Genomics Consortium reaches project milestone ahead of schedule

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