The SGC at the Center of Medicinal Chemistry of UNICAMP (CQMED) is an affiliated SGC site. It is composed of a team of scientists who are dedicated on characterizing new potential disease targets and developing chemical probes for these targets. This site is located at the Universidade Estadual de Campinas in Brazil and focuses on characterizing Target enabling packages (TEPs) for understudied protein targets. These targets include areas such as female fertility, ribosomal quality control, RNA binding proteins and kinases in human and in infectious diseases.

Team’s capacities:

• Specialized in protein production in E. coli and Insect cells
• Develop Biochemical assays
• Develop chemical probes
• Develop NanoBRET tracers and NanoBret assay applied to infectious disease targets (parasites and bacteria)
• Integrate -omics methodologies and bioinformatics, including studies of alternative splicing
• Structural Biology
• Fragment-based drug discovery by LC-MS (Liquid chromatography coupled to mass spectrometry)
• Investigation of molecular mechanism of new proteins