Oxford

Towards an understanding of the role of DNA methylation in rheumatoid arthritis: therapeutic and diagnostic implications.

Cribbs A,Feldmann M,Oppermann U.
Therapeutic advances in musculoskeletal disease. 2015 doi: http://dx.doi.org/10.1177/1759720X15598307
PMID: 26425149

Discovery of ML324, a JMJD2 demethylase inhibitor with demonstrated antiviral activity.

Rai G,Kawamura A,Tumber A,Liang Y,Vogel JL,Arbuckle JH,Rose NR,Dexheimer TS,Foley TL,King ON,Quinn A,Mott BT,Schofield CJ,Oppermann U,Jadhav A,Simeonov A,Kristie TM,Maloney DJ.
Book. 2010 65 . doi: https://www.ncbi.nlm.nih.gov/books/NBK169450/
PMID: 24260783

Human UTY(KDM6C) is a male-specific N-methyl lysyl demethylase.

Walport LJ,Hopkinson RJ,Vollmar M,Madden SK,Gileadi C,Oppermann U,Schofield CJ,Johansson C.
The Journal of biological chemistry. 2014 289(26):18302-18313 . doi: http://dx.doi.org/10.1074/jbc.M114.555052
PMID: 24798337

Type 1 11beta-hydroxysteroid dehydrogenase as universal drug target in metabolic diseases?

Oppermann U.
Endocrine, metabolic & immune disorders drug targets. 2006 6(3):259-269 . doi: http://www.eurekaselect.com/77053/article
PMID: 17017977

Structural and mechanistic studies on gamma-butyrobetaine hydroxylase.

Leung IK,Krojer TJ,Kochan GT,Henry L,von Delft F,Claridge TD,Oppermann U,McDonough MA,Schofield CJ.
Chemistry & biology. 2010 17(12):1316-1324 . doi: http://dx.doi.org/10.1016/j.chembiol.2010.09.016
PMID: 21168767

NVS-BPTF-1

FOP Friends and FOP France renewed partnership with SGC Oxford

SGC at the University of Oxford is pleased to announce that two patient foundations, FOP Friends and FOP France, have renewed their long standing partnership with SGC Oxford to support research into the rare congenital syndrome fibrodysplasia ossificans progressiva (FOP). The research led by Dr Alex Bullock aims to better define the molecular mechanisms that cause FOP and to develop new treatments.

Posted Wednesday 13th February 2019