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The successful segregation of chromosomes in mitosis requires the timely coordination of cell cycle events to ensure the bipo¬lar attachment of sister chromatids via their kinetochores to the mitotic spindle before the initiation of anaphase. Deregulation of this process or uncoupling of its…
Apicomplexan parasites are a diverse group of protozoan parasites, several of which cause important human and animal diseases, such as malaria, cryptosporidiosis and toxoplasmosis. Many of these diseases are endemic in developing countries, which are impacted by the lack of cost-efficient…
Toxoplasmosis is a parasitic disease caused by the apicomplexan protozoa Toxoplasma gondii and can pose a significant threat to immunocompromised individuals, e.g. those undergoing organ transplantation or chemotherapy and HIV/AIDS patients, who cannot fight back the infection and are thus…
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