Cheryl Arrowsmith is a Senior Scientist at the Princess Margaret Cancer Centre, Professor in the Department of Medical Biophysics, University of Toronto, and the Chief Scientist of the Structural Genomics Consortium (SGC) at the University of Toronto. Her research focuses on the structural and chemical biology of chromatin and epigenetic regulatory factors especially as relates to cancer and drug discovery. In partnership with major pharmaceutical companies, she leads the SGC’s international open science program that is developing and distributing unencumbered Chemical Probes that support the discovery of new medicines. She received her Ph.D. from the University of Toronto and carried out postdoctoral research at Stanford University, and was co-founder of Affinium Pharmaceuticals, which developed a new medicine for multidrug resistant bacteria. She has published over 300 research articles and was recognized by Clarivate Analytics as being among the worlds top 1% of highly cited scientists in 2018, 2019 and 2022. She was elected an AAAS Fellow (2015), and a Fellow of the Royal Society of Canada (2020).
Liao JC, Lam R, Brazda V, Duan S, Ravichandran M, Ma J, Xiao T, Tempel W, Zuo X, Wang YX, Chirgadze NY, Arrowsmith CH
Structure. 2011-3-9 . 19(3):418-29 .doi: 10.1016/j.str.2010.12.015
PMID: 21397192Yap DB, Chu J, Berg T, Schapira M, Cheng SW, Moradian A, Morin RD, Mungall AJ, Meissner B, Boyle M, Marquez VE, Marra MA, Gascoyne RD, Humphries RK, Arrowsmith CH, Morin GB, Aparicio SA
Blood. 2011-2-24 . 117(8):2451-9 .doi: 10.1182/blood-2010-11-321208
PMID: 21190999Shloush J, Vlassov JE, Engson I, Duan S, Saridakis V, Dhe-Paganon S, Raught B, Sheng Y, Arrowsmith CH
J. Biol. Chem.. 2011-2-11 . 286(6):4796-808 .doi: 10.1074/jbc.M110.157669
PMID: 21084285Kaustov L, Ouyang H, Amaya M, Lemak A, Nady N, Duan S, Wasney GA, Li Z, Vedadi M, Schapira M, Min J, Arrowsmith CH
J. Biol. Chem.. 2011-1-7 . 286(1):521-9 .doi: 10.1074/jbc.M110.191411
PMID: 21047797Ko S, Kang GB, Song SM, Lee JG, Shin DY, Yun JH, Sheng Y, Cheong C, Jeon YH, Jung YK, Arrowsmith CH, Avvakumov GV, Dhe-Paganon S, Yoo YJ, Eom SH, Lee W
J. Biol. Chem.. 2010-11-12 . 285(46):36070-80 .doi: 10.1074/jbc.M110.145219
PMID: 20826778Liu F, Chen X, Allali-Hassani A, Quinn AM, Wigle TJ, Wasney GA, Dong A, Senisterra G, Chau I, Siarheyeva A, Norris JL, Kireev DB, Jadhav A, Herold JM, Janzen WP, Arrowsmith CH, Frye SV, Brown PJ, Simeonov A, Vedadi M, Jin J
J. Med. Chem.. 2010-8-12 . 53(15):5844-57 .doi: 10.1021/jm100478y
PMID: 20614940Vedadi M, Arrowsmith CH, Allali-Hassani A, Senisterra G, Wasney GA
J. Struct. Biol.. 2010-5-11 . 172(1):107-19 .doi: 10.1016/j.jsb.2010.05.005
PMID: 20466062Campagna-Slater V, Arrowsmith AG, Zhao Y, Schapira M
J Chem Inf Model. 2010-3-22 . 50(3):358-67 .doi: 10.1021/ci900427b
PMID: 20112952Wu H, Min J, Lunin VV, Antoshenko T, Dombrovski L, Zeng H, Allali-Hassani A, Campagna-Slater V, Vedadi M, Arrowsmith CH, Plotnikov AN, Schapira M
PLoS ONE. 2010-1-11 . 5(1):e8570 .doi: 10.1371/journal.pone.0008570
PMID: 20084102Liu F, Chen X, Allali-Hassani A, Quinn AM, Wasney GA, Dong A, Barsyte D, Kozieradzki I, Senisterra G, Chau I, Siarheyeva A, Kireev DB, Jadhav A, Herold JM, Frye SV, Arrowsmith CH, Brown PJ, Simeonov A, Vedadi M, Jin J
J. Med. Chem.. 2009-12-24 . 52(24):7950-3 .doi: 10.1021/jm901543m
PMID: 19891491