Opher Gileadi obtained his PhD in Biochemistry at the Hebrew University and was then a postdoctoral fellow at Stanford University Medical School. Subsequently he led a research group at the Weizmann Institute of Science. From 2004-2021 he was both at SGC University of Oxford, first as head of the Biotechnology group, then as Principal Investigator of the Genome Integrity & Repair Group as well as Head of the SGC Kinase Chemical Biology Center at the State University of Campinas (UNICAMP). In 2021 Opher took at position as Executive Director, Protein Science and Structure at Exscientia, but re-join the SGC at Karolinska in 2023.
Opher leads the Protein Science team at SGC Karolinska, focussing on developing antibodies and target-enabling packages (TEPs) for under-investigated proteins of humans and pathogens.
Newman JA, Cooper CD, Roos AK, Aitkenhead H, Oppermann UC, Cho HJ, Osman R, Gileadi O
PLoS ONE. 2016-2-24 . 11(2):e0148762 .doi: 10.1371/journal.pone.0148762
PMID: 26910052Levy S, Allerston CK, Liveanu V, Habib MR, Gileadi O, Schuster G
Nucleic Acids Res.. 2016-1-29 . .doi: 10.1093/nar/gkw050
PMID: 26826708Broderick R, Nieminuszczy J, Baddock HT, Deshpande RA, Gileadi O, Paull TT, McHugh PJ, Niedzwiedz W
Nat. Cell Biol.. 2016-1-25 . .doi: 10.1038/ncb3303
PMID: 26807646Bavetsias V, Lanigan RM, Ruda GF, Atrash B, McLaughlin MG, Tumber A, Mok NY, Le Bihan YV, Dempster S, Boxall KJ, Jeganathan F, Hatch SB, Savitsky P, Velupillai S, Krojer T, England KS, Sejberg J, Thai C, Donovan A, Pal A, Scozzafava G, Bennett JM, Kawamura A, Johansson C, Szykowska A, Gileadi C, Burgess-Brown NA, von Delft F, Oppermann U, Walters Z, Shipley J, Raynaud FI, Westaway SM, Prinjha RK, Fedorov O, Burke R, Schofield CJ, Westwood IM, Bountra C, Müller S, van Montfort RL, Brennan PE, Blagg J
J. Med. Chem.. 2016-1-7 . .doi: 10.1021/acs.jmedchem.5b01635
PMID: 26741168Korczynska M, Le DD, Younger N, Gregori-Puigjané E, Tumber A, Krojer T, Velupillai S, Gileadi C, Nowak RP, Iwasa E, Pollock SB, Ortiz Torres I, Oppermann U, Shoichet BK, Fujimori DG
J. Med. Chem.. 2015-12-23 . .doi: 10.1021/acs.jmedchem.5b01527
PMID: 26699912Newman JA, Cooper CD, Aitkenhead H, Gileadi O
Structure. 2015-12-1 . 23(12):2319-30 .doi: 10.1016/j.str.2015.10.014
PMID: 26636256Allerston CK, Lee SY, Newman JA, Schofield CJ, McHugh PJ, Gileadi O
Nucleic Acids Res.. 2015-11-17 . .doi: 10.1093/nar/gkv1256
PMID: 26582912Brem J, van Berkel SS, Zollman D, Lee SY, Gileadi O, McHugh PJ, Walsh TR, McDonough MA, Schofield CJ
Antimicrob. Agents Chemother.. 2015-10-19 . .doi: 10.1128/AAC.01335-15
PMID: 26482303Newman JA, Savitsky P, Allerston CK, Bizard AH, Özer Ö, Sarlós K, Liu Y, Pardon E, Steyaert J, Hickson ID, Gileadi O
Nucleic Acids Res.. 2015-4-21 . .doi: 10.1093/nar/gkv373
PMID: 25901030Cooper CD, Newman JA, Aitkenhead H, Allerston CK, Gileadi O
J. Biol. Chem.. 2015-4-12 . .doi: 10.1074/jbc.M115.646737
PMID: 25866208