Opher Gileadi obtained his PhD in Biochemistry at the Hebrew University and was then a postdoctoral fellow at Stanford University Medical School. Subsequently he led a research group at the Weizmann Institute of Science. From 2004-2021 he was both at SGC University of Oxford, first as head of the Biotechnology group, then as Principal Investigator of the Genome Integrity & Repair Group as well as Head of the SGC Kinase Chemical Biology Center at the State University of Campinas (UNICAMP). In 2021 Opher took at position as Executive Director, Protein Science and Structure at Exscientia, but re-join the SGC at Karolinska in 2023.
Opher leads the Protein Science team at SGC Karolinska, focussing on developing antibodies and target-enabling packages (TEPs) for under-investigated proteins of humans and pathogens.
Berridge G, Chalk R, D'Avanzo N, Dong L, Doyle D, Kim JI, Xia X, Burgess-Brown N, Deriso A, Carpenter EP, Gileadi O
Anal. Biochem.. 2011-3-15 . 410(2):272-80 .doi: 10.1016/j.ab.2010.11.008
PMID: 21093405Froese DS, Kochan G, Muniz JR, Wu X, Gileadi C, Ugochukwu E, Krysztofinska E, Gravel RA, Oppermann U, Yue WW
J. Biol. Chem.. 2010-12-3 . 285(49):38204-13 .doi: 10.1074/jbc.M110.177717
PMID: 20876572Lucic B, Zhang Y, King O, Mendoza-Maldonado R, Berti M, Niesen FH, Burgess-Brown NA, Pike AC, Cooper CD, Gileadi O, Vindigni A
Nucleic Acids Res.. 2010-11-8 . 39(5):1703-17 .doi: 10.1093/nar/gkq1031
PMID: 21059676Panigrahi GB, Slean MM, Simard JP, Gileadi O, Pearson CE
Proc. Natl. Acad. Sci. U.S.A.. 2010-7-13 . 107(28):12593-8 .doi: 10.1073/pnas.0909087107
PMID: 20571119Savitsky P, Bray J, Cooper CD, Marsden BD, Mahajan P, Burgess-Brown NA, Gileadi O
J. Struct. Biol.. 2010-6-10 . 172(1):3-13 .doi: 10.1016/j.jsb.2010.06.008
PMID: 20541610Vindigni A, Marino F, Gileadi O
Biophys. Chem.. 2010-3-20 . 149(3):67-77 .doi: 10.1016/j.bpc.2010.03.012
PMID: 20392558Pike AC, Shrestha B, Popuri V, Burgess-Brown N, Muzzolini L, Costantini S, Vindigni A, Gileadi O
Proc. Natl. Acad. Sci. U.S.A.. 2009-1-27 . 106(4):1039-44 .doi: 10.1073/pnas.0806908106
PMID: 19151156Gileadi O, Burgess-Brown NA, Colebrook SM, Berridge G, Savitsky P, Smee CE, Loppnau P, Johansson C, Salah E, Pantic NH
Methods Mol. Biol.. 2008-6-11 . 426:221-46 .doi: 10.1007/978-1-60327-058-8_14
PMID: 18542867Shrestha B, Smee C, Gileadi O
Methods Mol. Biol.. 2008-3-29 . 439:269-89 .doi: 10.1007/978-1-59745-188-8_19
PMID: 18370110Gräslund S, Nordlund P, Weigelt J, Hallberg BM, Bray J, Gileadi O, Knapp S, Oppermann U, Arrowsmith C, Hui R, Ming J, dhe-Paganon S, Park HW, Savchenko A, Yee A, Edwards A, Vincentelli R, Cambillau C, Kim R, Kim SH, Rao Z, Shi Y, Terwilliger TC, Kim CY, Hung LW, Waldo GS, Peleg Y, Albeck S, Unger T, Dym O, Prilusky J, Sussman JL, Stevens RC, Lesley SA, Wilson IA, Joachimiak A, Collart F, Dementieva I, Donnelly MI, Eschenfeldt WH, Kim Y, Stols L, Wu R, Zhou M, Burley SK, Emtage JS, Sauder JM, Thompson D, Bain K, Luz J, Gheyi T, Zhang F, Atwell S, Almo SC, Bonanno JB, Fiser A, Swaminathan S, Studier FW, Chance MR, Sali A, Acton TB, Xiao R, Zhao L, Ma LC, Hunt JF, Tong L, Cunningham K, Inouye M, Anderson S, Janjua H, Shastry R, Ho CK, Wang D, Wang H, Jiang M, Montelione GT, Stuart DI, Owens RJ, Daenke S, Schütz A, Heinemann U, Yokoyama S, Büssow K, Gunsalus KC
Nat. Methods. 2008-2-1 . 5(2):135-46 .doi: 10.1038/nmeth.f.202
PMID: 18235434