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Oxford
Artemis (DCLRE1C, SNM1C)
Currently several radio-sensitising and chemotherapeutic agents are used in conjunction with radiotherapy to enhance the efficacy of cancer treatment. DCLRE1C/Artemis is a major player in both programmed (V(D)J) recombination and non-programmed c-NHEJ DSB repair. This makes Artemis and other DSB repair enzymes an attractive pharmacological target for the radiosensitisation of tumours.
Human T-box transcription factor T (Brachyury)
Chordoma is a rare cancer occurring along the spinal cord (OMIM: 215400). Chordoma is derived from an embryonic tissue, the notochord, and over-expresses the embryonic transcription factor T-box transcription factor T, the homologue of mouse Brachyury
Postdoctoral Scientist in Structural Biology
Applications are invited for a highly motivated Postdoctoral Scientist in Structural Biology to work with the Centre for Medicines Discovery (CMD).
Research Assistant
We are seeking to appoint a Research Assistant for the Centre for Medicines Discovery (CMD). This post will be working under the guidance of the Principle Investigator and a postdoctoral scientist on all aspects of the research in the group.
Research Assistant in Cloning and Protein Production
Research Assistant – Chemical Biology (Target Engagement & Screening)
Reporting to the Chemical Probes Group Leader, the main responsibility of this post is to perform and develop cellular assays and model systems to study the function of disease-relevant genes and determine the cellular effects of small molecule probes using a variety of functional assays.
Research Software Engineer
We are seeking to appoint a Research Software Engineer to join the Centre for Medicines Discovery to support the ongoing high-throughput serology screening platform at the University of Oxford. This is an exciting opportunity to join a multi-disciplinary team who are providing rapid and cutting-edge COVID-19 tests for hundreds of thousands of patient samples from across the UK over the coming year.
Postdoctoral Scientist – Protein Biochemistry & Structural Biology
Research Assistant – Chemical Biology (Molecular & Cellular Biology)
We are seeking a Research Assistant in Chemical Biology (Molecular & Cellular Biology). Reporting to the Chemical Biology & Chemical Probes Group Leader, the main responsibility of this post is to perform and develop cellular assays and model systems to study the function of disease-relevant genes and determine the cellular effects of small molecule probes using a variety of functional assays.
Postdoctoral Scientist – Small Molecules Modulating Protein Function
We are seeking a highly enthusiastic and dedicated Postdoctoral Research Scientist to work on development of a chemogenomics compound library in Dr. Jon Elkins' group.