Alex Bullock: Understanding growth signals
Growth factors and signals are fundamental to many diseases. A single point mutation in the DNA coding for a bone morphogenetic protein is responsible for the development of Fibrodysplasia ossificans progressiva (FOP), a very debilitating disease where muscles are progressively turned into bones. Understanding these mechanisms allowed the selection of a drug, currently used to treat cancer, that may possibly be repurposed to treat FOP.
Learn more about the methods Dr Alex Bullockuses and the development of new drugs in NDM series of podcasts on Revolutionary Biology.