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Research Associate Professor (UNC) - Principal Investigator (SGC)
David Drewry is a renowned leader in the medicinal chemistry of protein kinases and is one of the principal architects of the research strategy at the SGC-UNC to build an open and collaborative research network to promote target discovery. He previously enjoyed more than 24 years as a medicinal chemist with GlaxoSmithKline and legacy companies, where he led teams working across the preclinical spectrum of drug discovery. His research interests include the art and science of medicinal chemistry, kinase inhibitor design, utilization of annotated sets of kinase inhibitors to build understanding of signaling networks and precompetitive chemical biology to facilitate target identification. After earning a Bachelor’s of Science degree, cum laude, in chemistry from Yale University, Drewry earned his doctorate at the University of California, Berkeley in the laboratory of Paul Bartlett, working on the design, synthesis and mechanistic studies of zinc protease inhibitors. Drewry is currently the head of chemistry at Meryx Pharmaceuticals, a biotech startup focused on small-molecule inhibitors of Mer kinase that was a spinoff from the UNC Eshelman School of Pharmacy. Drewry enjoys running, reading and relaxing with his family at local restaurants, the movie theater or in the kitchen playing board games.
Curr. Opinion in Chem Biol.. 2010 289-298. doi: 10.1016/j.cbpa.2010.03.024
PMID: 20413343
2015
J. Med. Chem.. 04.30.2015 . doi: 10.1021/acs.jmedchem.5b00256
PMID: 25856009
Sci. Rep.. 03.05.2015 5:8771. doi: 10.1038/srep08771
PMID: 25740547
2013
PLoS One. 2013 8(3):e57888. doi: 10.1371/journal.pone.0057888
PMID: 23505445
Future Med. Chem.. 2013 2295-310. doi: 10.4155/fmc.12.183
PMID: 23234552
2010
J Org Chem.. 10.01.2010 6693-5. doi: 10.1021/jo101077g
PMID: 20804180
J. Med. Chem.. 05.27.2010 3973-4001. doi: 10.1021/jm901870q
PMID: 20420387
Curr. Opinion in Chem Biol.. 06.14.2010 289-298. doi: 10.1016/j.cbpa.2010.03.024
PMID: 20413343
2009
Bioorg. Med. Chem. Lett.. 02.01.2009 1018-1021. doi: 10.1016/j.bmcl.2008.11.041
PMID: 19097784
2008
J. Chem Inf. and Model.. 12.2008 2395-2403. doi: 10.1021/ci800276t
PMID: 19053525
J. Med. Chem.. 12.25.2008 7898-7914. doi: 10.1021/jm8011036
PMID: 19035792