Skip to main content

Search form

Search

About
A public-private partnership that supports the discovery of new medicines through open access research.
About SGC

Partners

Research Laboratories

SGC-Toronto

SGC-UNC

SGC-Frankfurt

SGC-Karolinska

SGC-Neuro

Governance

Collaborators

Open Science

Equity, Diversity and Inclusion

Impact
Science and Resources
Proteins

Structure Gallery

Expression Vectors

Plasmids

Constructs

Production Protocols

ChromoHub Phylogenetic Trees

UbiHub Phylogenetic Trees

ChemBioPort
Chemical Probes Program

CHEMICAL PROBES

Donated chemical probes

Chemical Handles

Human Kinase Chemical Probe Program

ANTIBODIES

TARGET ENABLING PACKAGES (TEPs)

TISSUE PLATFORM

Open Lab Notebooks

Open Chemistry Network

PUBLICATIONS
People
Global

Aled Edwards, CEO

Susan McCormick, CFO

Max Morgan, General Counsel and Public Policy Director
SGC Toronto

Cheryl Arrowsmith

Dalia Barsyte-Lovejoy

Takis Prinos

Matthieu Schapira

Levon Halabelian

Rachel Harding

SGC UNC

Tim Willson

Alison Axtman

David Drewry

Peter J. Brown

Rafael M. Couñago

SGC UCL

Mat Todd

SGC Karolinska

Michael Sundström

Opher Gileadi
SGC Frankfurt

Stefan Knapp

Susanne Müller-Knapp

Thomas Hanke

Vladimir Rogov

Krishnal Saxena

Andreas Joerger

Václav Němec

Andreas Krämer

Sandra Röhm

SGC Neuro

Edward Fon

Thomas Durcan

Jean-François Trempe

Ziv Gan-Or

Peter McPherson

Carl Laflamme

Roxanne Lariviere
News & Outreach
News & Events

News from SGC

Press Releases

Events

Blog
Tweets by thesgconline
Careers

Home » Science and Resources » Proteins » Structure Gallery

Structure Gallery

Text Search

Families

Diseases

Status

Group

Site

Added After

Date

E.g., 03/10/2023

Added Before

Date

E.g., 03/10/2023

Has datapack

2281 structures found


	PDB: 8GCY Target: CBLB Deposited: 03/03/2023 Human E3 ubiquitin-protein ligase CBL-B, TKB domain, in complex with N-Aryl isoindolin-1-one Target Class: Ubiquitylation - E3 Ligases Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 8G5E Target: SETDB1 Deposited: 13/02/2023 Human histone-lysine N-methyltransferase SETDB1, triple Tudor domain, in complex with compound UNC6535 Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 8G2F Target: PRMT3 Deposited: 03/02/2023 Human protein arginine N-methyltransferase 3, methyltransferase domain, in complex with compound II710 Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: MedChem


	PDB: 8G2I Target: CARM1 Deposited: 03/02/2023 Human protein arginine methyltransferase CARM1, methyltransferase domain, in complex with compound YD1290 Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 8F8E Target: DCAF1 Deposited: 21/11/2022 Human DDB1- and CUL4-associated factor 1, WDR domain, in complex with small molecule OICR-8268 Target Class: WDR Disease Areas: Signalling Site: Toronto Status: Follow-up not counted


	PDB: 8F0W Target: 53BP1 Deposited: 04/11/2022 Human TP53 binding protein tandem Tudor domain in complex with MFP-5956 Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 8EOM Target: 53BP1 Deposited: 03/10/2022 Human TP53 binding protein, tandem Tudor domain, in complex with compound MFP-5973 Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 8EM8 Target: pfPKG Deposited: 27/09/2022 Plasmodium falciparum cGMP-dependent protein kinase PKG in complex with RY-1-165 Target Class: Kinase-Other Disease Areas: Parasitic disease Site: Toronto Status: MedChem


	PDB: 8DYS Target: EIF2A Deposited: 05/08/2022 Human eukaryotic translation initiation factor 2A, WDR domain Target Class: WDR Disease Areas: Signalling Site: Toronto Status: Counted


	PDB: 8D41 Target: COPB2 Deposited: 01/06/2022 Human Coatomer subunit beta, WDR domain, in complex with covalent fragment OICR-6254 Target Class: WDR Disease Areas: Cancer Site: Toronto Status: MedChem


	PDB: 8D30 Target: COPB2 Deposited: 31/05/2022 Human Coatomer subunit beta, WDR domain Target Class: WDR Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 7UW7 Target: TRIP12 Deposited: 02/05/2022 Human E3 ubiquitin-protein ligase TRIP12 isoform 2, WWE domain, in complex with ADP Target Class: Ubiquitylation - E3 Ligases Disease Areas: Signalling and cancer Site: Toronto Status: Counted


	PDB: 7UFV Target: DCAF1 Deposited: 23/03/2022 Human DDB1- and CUL4-associated factor 1, WDR domain, in complex with small molecule OICR-6766 Target Class: Ubiquitylation - E3 Ligases, WDR Disease Areas: Signalling Site: Toronto Status: MedChem


	PDB: 7U8I Target: CARM1 Deposited: 08/03/2022 Human histone-arginine methyltransferase CARM1 in complex with bi-substrate inhibitor MT556 Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: MedChem


	PDB: 7T39 Target: PRMT9 Deposited: 07/12/2021 Human protein arginine N-methyltransferase 9, methyltransferase domain, in complex with inhibitor MT221 Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 7SUL Target: SEC31A Deposited: 17/11/2021 Human protein transport protein Sec31A, WDR domain Target Class: WDR Disease Areas: Signalling Site: Toronto Status: Counted


	PDB: 7STY Target: CORO1C Deposited: 15/11/2021 Human Coronin-1C, WDR domain Target Class: WDR Disease Areas: Signalling Site: Toronto Status: Counted


	PDB: 7SSE Target: DCAF1 Deposited: 10/11/2021 Human DDB1- and CUL4-associated factor 1, WDR domain, in complex with small molecule CYCA-117-70 Target Class: Ubiquitylation - E3 Ligases, WDR Disease Areas: Signalling and cancer Site: Toronto Status: MedChem


	PDB: 7SLZ Target: GID4 Deposited: 25/10/2021 Human glucose-induced degradation protein 4 homolog, substrate binding domain, in complex with chemical probe PFI-7 Target Class: Ubiquitylation - E3 Ligases Disease Areas: Signalling Site: Toronto Status: MedChem


	PDB: 7S12 Target: GID4 Deposited: 31/08/2021 Human glucose-induced degradation protein 4 homolog, substrate binding domain, in complex with small molecule UBF9092 Target Class: Ubiquitylation - E3 Ligases Disease Areas: Signalling Site: Toronto Status: MedChem


	PDB: 7RUO Target: UTP15 Deposited: 17/08/2021 Human U3 small nucleolar RNA-associated protein 15 homolog, WDR domain Target Class: WDR Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 7RBQ Target: PRMT9 Deposited: 06/07/2021 Human protein arginine N-methyltransferase 9, methyltransferase domain, in complex with inhibitor MT556 Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Counted


	PDB: 7MT1 Target: PAFAH1B1 Deposited: 12/05/2021 Human platelet-activating factor acetylhydrolase IB subunit beta, WDR domain Target Class: WDR Disease Areas: Neurobiology Site: Toronto Status: Counted


	PDB: 7MEQ Target: TMPRSS2 Deposited: 07/04/2021 Human Transmembrane protease serine 2, SRCR and serine protease domains, in complex with Nafamostat Target Class: Proteases Disease Areas: COVID Site: Toronto Status: Counted


	PDB: 7M3X Target: RBBP7 Deposited: 19/03/2021 Human histone-binding protein RBBP7 Target Class: WDR Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 7LQT Target: PPP1R10 Deposited: 15/02/2021 Serine/threonine-protein phosphatase 1 regulatory subunit 10, PPP1R10, N-terminal TFIIS domain, fused to Myc Homology Box 0 Target Class: Miscellaneous Disease Areas: Cancer Site: Status: Counted


	PDB: 7LMT Target: WHSC1 Deposited: 05/02/2021 Human Histone-lysine N-methyltransferase NSD2, first PWWP domain, in complex with MRT10241866a Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 7LH9 Target: BRD1 Deposited: 21/01/2021 Human Bromodomain-containing protein 1, PWWP domain, in complex with DNA Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: Counted


	PDB: 7KYX Target: CORO6 Deposited: 09/12/2020 Human Coronin-6, WDR domain Target Class: WDR Disease Areas: Signalling Site: Toronto Status: Counted


	PDB: 7KXT Target: EED Deposited: 04/12/2020 Human Polycomb protein EED, WDR domain, in complex with Astemizole Target Class: WDR Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 7KQQ Target: WDR55 Deposited: 16/11/2020 WD repeat-containing protein 55, WDR domain Target Class: WDR Disease Areas: Signalling Site: Toronto Status: Counted


	PDB: 7KLJ Target: KIF21A Deposited: 04/11/2020 Human Kinesin-like protein KIF21A, WDR domain Target Class: WDR Disease Areas: Signalling Site: Toronto Status: Counted


	PDB: 7JYA Target: FEM1C Deposited: 29/08/2020 Human E3 ligase protein fem-1 homolog C, ankyrin repeat, in complex with peptide Target Class: Ubiquitylation - E3 Ligases Disease Areas: Signalling Site: Toronto Status: Counted


	PDB: 6XKC Target: FEM1C Deposited: 25/06/2020 Human protein fem-1 homolog C, N-terminal ankyrin repeat Target Class: Ubiquitylation - E3 Ligases Disease Areas: Signalling Site: Toronto Status: Counted


	PDB: 6XKB Target: SCAF4 Deposited: 25/06/2020 Human SR-related and CTD-associated factor 4, CID domain, in complex with peptide S2,S5p-CTD Target Class: Miscellaneous Disease Areas: Signalling Site: Toronto Status: Counted


	PDB: 6XCG Target: WHSC1 Deposited: 08/06/2020 Human histone-lysine N-methyltransferase NSD2, first PWWP domain, in complex with chemical probe UNC6934 Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 6WZZ Target: GID4 Deposited: 14/05/2020 Human Glucose-induced degradation protein 4, substrate binding domain, in complex VGLWKS peptide Target Class: Ubiquitylation - E3 Ligases Disease Areas: Signalling Site: Toronto Status: Follow-up official


	PDB: 6YWL Target: CVNSP3B Deposited: 30/04/2020 Crystal structure of SARS-CoV-2 (Covid-19) NSP3 macrodomain in complex with ADP-ribose Target Class: Disease Areas: SARS-COV-2 Site: Frankfurt Status:


	PDB: 6YWK Target: CVNSP3B Deposited: 30/04/2020 Crystal structure of SARS-CoV-2 (Covid-19) NSP3 macrodomain in complex with HEPES Target Class: Disease Areas: SARS-COV-2 Site: Frankfurt Status:


	PDB: 6YWM Target: CVNSP3B Deposited: 30/04/2020 Crystal structure of SARS-CoV-2 (Covid-19) NSP3 macrodomain in complex with MES Target Class: Disease Areas: SARS-COV-2 Site: Frankfurt Status:

FBXW11/SKP1 - Beta Catenin


	PDB: 6WNX Target: FBXW11/SKP1 - Beta Catenin Deposited: 23/04/2020 Human F-box/WD repeat-containing protein 11, F-box and WDR domains, in complex with SKP1 and a pSer33/pSer37 Beta-Catenin peptide Target Class: Ubiquitylation - E3 Ligases, WDR Disease Areas: Signalling and cancer Site: Toronto Status: Counted


	PDB: 6WHH Target: WDR41 Deposited: 08/04/2020 Human WD repeat-containing protein 41, WDR domain Target Class: WDR Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 6WAT Target: PHF1 Deposited: 31/03/2020 Human PHD finger protein 1, Tudor domain, in complex with H3K27me3 peptide Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6WAV Target: PHF1 Deposited: 31/03/2020 Human PHD finger protein 1, Tudor domain, in complex with H3K36me3 peptide Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6WAU Target: PHF19 Deposited: 31/03/2020 Human PHD finger protein 19, Tudor domain, in complex with H3K27me3 peptide Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6WAJ Target: NLE1 Deposited: 25/03/2020 Human Notchless protein homolog 1, N-terminal ubiquitin-like domain Target Class: Miscellaneous Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 6VYC Target: WDR91 Deposited: 26/02/2020 Human WD repeat-containing protein 91, WDR domain Target Class: WDR Disease Areas: Signalling Site: Toronto Status: Counted


	PDB: 6VTI Target: PPP1R10 Deposited: 12/02/2020 Human Serine/threonine-protein phosphatase 1 regulatory subunit 10, N-terminal domain Target Class: Miscellaneous Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 6VAH Target: TEAD2 Deposited: 23/12/2019 Human TEA domain transcription factor 2, YAP binding domain, in complex with flufenamic acid derivative Target Class: Miscellaneous Disease Areas: Signalling and cancer Site: Toronto Status: Follow-up official


	PDB: 6VCS Target: UHRF1 Deposited: 23/12/2019 Human ubiquitin like with PHD and ring finger domains 1, SRA domain, in complex with DNA Target Class: Miscellaneous Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6VA5 Target: 53BP1 Deposited: 20/12/2019 Human tumor protein p53 binding protein 1, tudor domain, in complex with inhibitor MFP-4184 Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 6V9T Target: TDRD3 Deposited: 16/12/2019 Human tudor domain containing 3, tudor domain, in complex with small molecule Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: MedChem


	PDB: 6V3N Target: CDYL2 Deposited: 10/12/2019 Human chromodomain Y like 2, chromodomain, in complex with H3K27me3 peptide Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6TN8 Target: ACVR1 Deposited: 06/12/2019 Human activin A receptor type 1 Target Class: Protein Kinase/TKL Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6V41 Target: CDY1 Deposited: 27/11/2019 Human chromodomain Y-linked 1, chromodomain, in complex with H3K9me3 peptide Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6V2S Target: MPP8 Deposited: 25/11/2019 Human M-phase phosphoprotein 8, chromodomain, in complex with peptido-mimetic UNC3866 Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 6V2D Target: CDYL2 Deposited: 22/11/2019 Human chromodomain Y like 2, chromodomain, in complex with peptido-mimetic UNC3866 Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: MedChem


	PDB: 6T8N Target: ACVR1 Deposited: 24/10/2019 Human activin A receptor type 1 Target Class: Protein Kinase/TKL Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6UPT Target: 53BP1 Deposited: 18/10/2019 Human tumor protein p53 binding protein 1, tudor domain, in complex with inhibitor MFP-2706 Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 6T6D Target: ACVR1 Deposited: 18/10/2019 Human activin A receptor type 1 Target Class: Protein Kinase/TKL Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6SZM Target: ACVR1 Deposited: 02/10/2019 Human activin A receptor type 1 Target Class: Protein Kinase/TKL Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6UHD Target: HAT1 Deposited: 27/09/2019 Human histone acetyltransferase 1, full length, in complex with isobutyryl-CoA and H4K12A mutant Target Class: Chromatin Regulation, Transferases Disease Areas: Epigenetics Site: Toronto Status: Follow-up official


	PDB: 6SY1 Target: DHTKD1 Deposited: 26/09/2019 Human dehydrogenase E1 and transketolase domain containing 1 Target Class: Oxidoreductases Disease Areas: Metabolism Site: Oxford Status: Counted


	PDB: 6UE6 Target: WHSC1 Deposited: 20/09/2019 Human nuclear receptor binding SET domain protein 2, first PWWP domain, in complex with small molecule MR837 Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 6SRH Target: ACVR1 Deposited: 05/09/2019 Human activin A receptor type 1 Target Class: Protein Kinase/TKL Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6SFO Target: MAPK14A Deposited: 01/08/2019 MAPK14 with bound inhibitor SR-318 Target Class: Protein Kinase/CMGC Disease Areas: Site: Frankfurt Status: Follow-up not counted


	PDB: 6SE4 Target: BRD4 Deposited: 29/07/2019 Human bromodomain containing 4 Target Class: Bromodomain Disease Areas: Cancer and epigenetics Site: Oxford Status: MedChem


	PDB: 6S5F Target: RAB39B Deposited: 01/07/2019 Human RAB39B, member RAS oncogene family Target Class: Vesicle Transport Disease Areas: Cancer Site: Oxford Status: Counted


	PDB: 6S5H Target: RAB38 Deposited: 01/07/2019 Human RAB38, member RAS oncogene family Target Class: Vesicle Transport Disease Areas: Cancer Site: Oxford Status: Counted


	PDB: 6PFL Target: HUWE1 Deposited: 21/06/2019 Human HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase, WWE domain, in complex with ADP-ribose Target Class: Ubiquitin Related Biology Disease Areas: Cancer Site: Toronto Status: Follow-up official


	PDB: 6PED Target: N6AMT1-TRMT112 Deposited: 20/06/2019 Human methyltransferase dimer N6AMT1-TRMT112, methyltransferase domain, in complex with S-adenosyl-homocysteine Target Class: Methyltransferases Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 6PDM Target: PRMT9 Deposited: 19/06/2019 Human protein arginine methyltransferase 9, full-length Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6PBG Target: COPA Deposited: 13/06/2019 Human coatomer protein complex subunit alpha, WDR domain Target Class: WDR Disease Areas: Neurobiology Site: Toronto Status: Counted


	PDB: 6P7I Target: HRMT1L6 Deposited: 05/06/2019 Human protein arginine methyltransferase 6, full-length, in complex with covalent inhibitor YS17-117 Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 6P0R Target: SUV39H2 Deposited: 17/05/2019 Human suppressor of variegation 3-9 homolog 2, methyltransferase domain, in complex with inhibitor OTS186935 Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 6P0Q Target: WDR12 Deposited: 17/05/2019 Human WD repeat domain 12, ubiquitin-like domain Target Class: Ubiquitin Related Biology Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 6OQM Target: MSH6 Deposited: 26/04/2019 Human mutS homolog 6, PWWP domain Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6FNU Target: MET12SCA Deposited: 17/04/2019 Structure of S. cerevisiae Methylenetetrahydrofolate reductase 1, catalytic domain Target Class: Disease Areas: Site: Oxford Status: Official


	PDB: 6NP7 Target: BDF2 Deposited: 17/04/2019 Trypanosoma cruzi TcCLB.506553.20, bromodomain Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Counted


	PDB: 6RCT Target: CLK3A Deposited: 11/04/2019 Crystal structure of CLK3 in complex with T3-CLK Target Class: Protein Kinase/CMGC Disease Areas: Site: Frankfurt Status: Not counted


	PDB: 6RAA Target: CLK1A Deposited: 05/04/2019 CLK1 Kinase domain with bound imidazopyridin inhibitor T3-CLK Target Class: Protein Kinase/CMGC Disease Areas: Site: Frankfurt Status: MedChem


	PDB: 6OGN Target: PRMT7 Deposited: 03/04/2019 Mouse protein arginine methyltransferase 7, full-length, in complex with chemical probe SGC8158 Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6OGK Target: MECP2 Deposited: 02/04/2019 Human methyl-CpG binding protein 2, MBD domain, in complex with A(5CM)AC DNA Target Class: Chromatin Regulation Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6OGJ Target: MECP2 Deposited: 02/04/2019 Human methyl-CpG binding protein 2, MBD domain, in complex with ACAC DNA Target Class: Chromatin Regulation Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6OEB Target: HMCES Deposited: 27/03/2019 Human 5-hydroxymethylcytosine binding ES cell specific, SRAP domain, in complex with 3' overhang DNA Target Class: RNA/DNA Processing/DNA-Repair Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 6OE7 Target: HMCES Deposited: 27/03/2019 Human 5-hydroxymethylcytosine binding ES cell specific, SRAP domain, cross-linked to DNA abasic site Target Class: RNA/DNA Processing/DNA-Repair Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 6OEA Target: HMCES Deposited: 27/03/2019 Human 5-hydroxymethylcytosine binding ES cell specific, SRAP domain, in complex with longer 3' overhang DNA Target Class: RNA/DNA Processing/DNA-Repair Disease Areas: Cancer Site: Toronto Status: Not counted


	PDB: 6QU2 Target: DYRK1AA Deposited: 26/02/2019 Crystal structure of DYRK1A complexed with FC162 inhibitor Target Class: Protein Kinase/CMGC Disease Areas: Signalling and cancer Site: Frankfurt Status: Not counted


	PDB: 6GI6 Target: ACVR1A Deposited: 07/02/2019 Crystal structure of the ACVR1 (ALK2) kinase in complex with a Quinazolinone based ALK2 inhibitor with a 5-methyl core. Target Class: Protein Kinase/TKL Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 5QHN Target: FAM83BA Deposited: 07/02/2019 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000622a Target Class: Cell Division Disease Areas: Cancer Site: Oxford Status: Follow-up not counted


	PDB: 6NM4 Target: PRDM9 Deposited: 10/01/2019 Human PR/SET domain 9, methyltransferase domain, in complex with chemical probe MRK-740 Target Class: Methyltransferases Disease Areas: Cancer Site: Toronto Status: MedChem


	PDB: 6QD5 Target: SLC14A1A Deposited: 31/12/2018 X-ray Structure of the Human Urea Channel SLC14A1/UT1 Target Class: Membrane proteins Disease Areas: Site: Oxford Status: Official


	PDB: 6NFX Target: MBTD1 Deposited: 29/12/2018 Human MBT domain-containing protein 1, MBT repeat, in complex with EPC1 peptide Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6NFT Target: USP05 Deposited: 20/12/2018 Human ubiquitin specific peptidase 5, second ZnF domain, in complex with inhibitor DAT194 Target Class: Deubiquitinating Enzymes - USP, Ubiquitin Related Biology Disease Areas: Signalling and cancer Site: Toronto Status: MedChem


	PDB: 6QB7 Target: KCTD16A Deposited: 20/12/2018 Structure of the H1 domain of human KCTD16 Target Class: Ubiquitin Related Biology Disease Areas: Site: Oxford Status: Official


	PDB: 6QAS Target: ULK1A Deposited: 19/12/2018 Crystal structure of ULK1 in complexed with PF-03814735 Target Class: Protein Kinase Disease Areas: Autophagy and cancer Site: Frankfurt Status: Follow-up official


	PDB: 6QAV Target: ULK2A Deposited: 19/12/2018 Crystal structure of ULK2 in complexed with MRT68921 Target Class: Protein Kinase Disease Areas: Autophagy and cancer Site: Frankfurt Status: Official


	PDB: 6QAU Target: ULK2A Deposited: 19/12/2018 Crystal structure of ULK2 in complexed with MRT67307 Target Class: Protein Kinase Disease Areas: Autophagy and cancer Site: Frankfurt Status: Follow-up official


	PDB: 6QAT Target: ULK2A Deposited: 19/12/2018 Crystal structure of ULK2 in complexed with hesperadin Target Class: Protein Kinase Disease Areas: Autophagy and cancer Site: Frankfurt Status: Follow-up official


	PDB: 6NEY Target: PP-BRD3 Deposited: 18/12/2018 Trypanosoma cruzi TcCLB.506755.120, bromodomain Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Counted


	PDB: 6NEZ Target: PP-BRD3 Deposited: 18/12/2018 Trypanosoma brucei BDF5 (Tb427tmp.01.5000), bromodomain, in complex with inhibitor PF-CBP1 Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Follow-up official


	PDB: 6Q8P Target: CLK1A Deposited: 16/12/2018 Structure of CLK1 with bound N-methyl-10-nitropyrido[3,4-g]quinazolin-2-amine Target Class: Protein Kinase/CMGC Disease Areas: Signalling and cancer Site: Frankfurt Status: Follow-up not counted


	PDB: 6Q8K Target: CLK1A Deposited: 15/12/2018 CLK1 with bound pyridoquinazoline inhibitor Target Class: Protein Kinase/CMGC Disease Areas: Signalling and cancer Site: Frankfurt Status: Follow-up not counted


	PDB: 6NIM Target: PP-BRD18 Deposited: 26/11/2018 Trypanosoma cruzi TcCLB.506553.20, bromodomain, in complex with bromosporine Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Follow-up official


	PDB: 6I8Y Target: SPIN1A Deposited: 22/11/2018 Crystal structure of Spindlin1 in complex with the Methyltransferase inhibitor A366 Target Class: Protein Kinase/STE Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6I8L Target: SPIN1A Deposited: 21/11/2018 Crystal structure of Spindlin1 in complex with the inhibitor TD001851a Target Class: SPINDLIN Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6I8B Target: SPIN1A Deposited: 20/11/2018 Crystal structure of Spindlin1 in complex with the inhibitor VinSpinIn Target Class: SPINDLIN Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6N31 Target: WDR12 Deposited: 14/11/2018 Human WD repeat domain 12, WDR domain Target Class: WDR Disease Areas: Signalling and cancer Site: Toronto Status: Counted


	PDB: 6I2Y Target: STK10A Deposited: 02/11/2018 Human STK10 bound to Foretinib Target Class: Protein Kinase/STE Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6HXF Target: STK10A Deposited: 17/10/2018 Human STK10 bound to a maleimide inhibitor Target Class: Protein Kinase/STE Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6HVD Target: SLKA Deposited: 11/10/2018 Human SLK bound to a maleimide inhibitor Target Class: Protein Kinase/STE Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6HT1 Target: MLLT1A Deposited: 02/10/2018 Crystal structure of MLLT1 (ENL) YEATS domain in complexed with SGC-iMLLT Target Class: YEATS Disease Areas: Cancer and epigenetics Site: Frankfurt Status: Follow-up official


	PDB: 6ht0 Target: MLLT1A Deposited: 02/10/2018 Crystal structure of MLLT1 (ENL) YEATS domain in complexed with compound 94 (a SGC iMLLT derivative) Target Class: YEATS Disease Areas: Cancer and epigenetics Site: Frankfurt Status: MedChem


	PDB: 6MLC Target: MLL3 Deposited: 29/09/2018 Human lysine methyltransferase 2C, 6th PHD domain, in complex with H4 peptide Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6ICT Target: SETD3 Deposited: 25/09/2018 Human SET Domain-Containing Protein 3, methyltransferase domain, in complex with methylated β-actin peptide Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6MIW Target: HUWE1 Deposited: 25/09/2018 Human HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase, WWE domain Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 6hpw Target: MLLT1A Deposited: 22/09/2018 Crystal structure of ENL (MLLT1) in complex with compound 20 (YTOOA000430a) Target Class: YEATS Disease Areas: Cancer and epigenetics Site: Frankfurt Status: MedChem


	PDB: 6hpx Target: MLLT1A Deposited: 22/09/2018 Crystal structure of ENL (MLLT1) in complex with compound 19 (benzimidazole fragment EF00114a) Target Class: YEATS Disease Areas: Cancer and epigenetics Site: Frankfurt Status: MedChem


	PDB: 6hpy Target: MLLT1A Deposited: 22/09/2018 Crystal structure of ENL (MLLT1) in complex with compound 12 (fragment EF00292) Target Class: YEATS Disease Areas: Cancer and epigenetics Site: Frankfurt Status: MedChem


	PDB: 6hpz Target: MLLT1A Deposited: 22/09/2018 Crystal structure of ENL (MLLT1) in complex with acetyllysine Target Class: YEATS Disease Areas: Cancer and epigenetics Site: Frankfurt Status: MedChem


	PDB: 6hq0 Target: MLLT1A Deposited: 22/09/2018 Crystal structure of ENL (MLLT1), apo form Target Class: YEATS Disease Areas: Cancer and epigenetics Site: Frankfurt Status: Follow-up not counted


	PDB: 6HP9 Target: DDR1A Deposited: 19/09/2018 Structure of the kinase domain of human DDR1 in complex with a 2-Amino-2,3-Dihydro-1H-Indene-5-Carboxamide-based inhibitor Target Class: Kinase-TK Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6MF9 Target: PP-BRD12 Deposited: 10/09/2018 Cryptosporidium parvum bromodomain containing protein 12 (cgd4_650), bromodomain, in complex with inhibitor BI-2536 Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Counted


	PDB: 6ICV Target: SETD3 Deposited: 07/09/2018 Human SET Domain-Containing Protein 3, methyltransferase domain, in complex with unmethylated β-actin peptide Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6MEW Target: RFXANK Deposited: 07/09/2018 Human regulatory factor X associated ankyrin containing protein, ankyrin repeat, in complex with a RFX7 peptide Target Class: Miscellaneous Disease Areas: Signalling Site: Toronto Status: Follow-up official


	PDB: 6HK6 Target: RIOK2A Deposited: 05/09/2018 Human RIOK2 bound to inhibitor Target Class: Protein Kinase Disease Areas: Site: Oxford Status: Official


	PDB: 6HDP Target: DYRK2 Deposited: 18/08/2018 Human dual specificity tyrosine phosphorylation regulated kinase 2 Target Class: Protein Kinase/CMGC Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6HDR Target: DYRK2 Deposited: 18/08/2018 Human dual specificity tyrosine phosphorylation regulated kinase 2 Target Class: Protein Kinase/CMGC Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6EDF Target: FYN Deposited: 09/08/2018 Human FYN proto-oncogene, Src family tyrosine kinase, SH3 domain Target Class: Miscellaneous Disease Areas: Signalling Site: Toronto Status: Not counted


	PDB: 6GYN Target: HCN4A Deposited: 30/06/2018 CryoEM structure of HCN4 Target Class: Membrane proteins Disease Areas: Site: Oxford Status: Official


	PDB: 6GYO Target: HCN4A Deposited: 30/06/2018 CryoEM structure of HCN4 with bound cAMP Target Class: Membrane proteins Disease Areas: Site: Oxford Status: Official


	PDB: 6DXT Target: USP05 Deposited: 29/06/2018 Human ubiquitin specific peptidase 5, second ZnF domain, in complex with inhibitor DAT180 Target Class: Deubiquitinating Enzymes - USP, Ubiquitin Related Biology Disease Areas: Signalling and cancer Site: Toronto Status: MedChem


	PDB: 6GY5 Target: KLHL20A Deposited: 28/06/2018 Crystal structure of the kelch domain of human KLHL20 in complex with DAPK1 peptide Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 6DXH Target: USP05 Deposited: 28/06/2018 Human ubiquitin specific peptidase 5, second ZnF domain, in complex with inhibitor DAT201 Target Class: Deubiquitinating Enzymes - USP, Ubiquitin Related Biology Disease Areas: Signalling and cancer Site: Toronto Status: MedChem


	PDB: 6GWR Target: DDR1A Deposited: 25/06/2018 Structure of the DDR1 kinase domain in complex with a heterocycloalkynylbenzimide inhibitor Target Class: Kinase-TK Disease Areas: Site: Oxford Status:


	PDB: 6DVR Target: CARM1 Deposited: 25/06/2018 Human coactivator associated arginine methyltransferase 1, methyltransferase domain, in complex with inhibitor (R)-SKI-72 Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 6DUB Target: LOC149281 Deposited: 20/06/2018 Human Alpha N-terminal protein methyltransferase 11B (a.k.a NTM1B), methyltransferase domain, in complex with SPKRI peptide substrate Target Class: Methyltransferases Disease Areas: Signalling Site: Toronto Status: Follow-up official


	PDB: 6GTT Target: STK10A Deposited: 18/06/2018 Human STK10 bound to BIRB-796 Target Class: Protein Kinase/STE Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6GRU Target: NUDT5A Deposited: 12/06/2018 Crystal structure of human NUDT5 Target Class: NUDIX Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 6GR8 Target: AURKC Deposited: 10/06/2018 Human aurora kinase C Target Class: Protein Kinase/Other Disease Areas: Cancer Site: Oxford Status: Counted


	PDB: 6GR9 Target: AURKC Deposited: 10/06/2018 Human aurora kinase C Target Class: Protein Kinase/Other Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 6GRA Target: STK6 Deposited: 10/06/2018 Human aurora kinase A Target Class: Protein Kinase/Other Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6GQD Target: GALTA Deposited: 07/06/2018 Structure of human galactose-1-phosphate uridylyltransferase (GALT), with crystallization epitope mutations A21Y:A22T:T23P:R25L Target Class: Disease Areas: Metabolism Site: Oxford Status: Follow-up official


	PDB: 6GMB Target: HAO1A Deposited: 06/06/2018 Structure of human hydroxyacid oxidase 1 bound with FMN and glycolate Target Class: Oxidoreductases Disease Areas: Site: Oxford Status:


	PDB: 6GPJ Target: GMDSA Deposited: 06/06/2018 Crystal structure of human GDP-D-mannose 4,6-dehydratase in complex with GDP-4F-Man Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6GMC Target: HAO1A Deposited: 06/06/2018 1.2 A resolution structure of human hydroxyacid oxidase 1 bound with FMN and 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole Target Class: Oxidoreductases Disease Areas: Site: Oxford Status:


	PDB: 6GPL Target: GMDSA Deposited: 06/06/2018 Crystal structure of human GDP-D-mannose 4,6-dehydratase in complex with GDP-4k6d-Man Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6GPK Target: GMDSA Deposited: 06/06/2018 Crystal structure of human GDP-D-mannose 4,6-dehydratase (E157Q) in complex with GDP-Man Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 5QIB Target: HAO1A Deposited: 22/05/2018 Crystal Structure of HAO1 in complex with FMOPL000388a Target Class: Disease Areas: Site: Oxford Status:


	PDB: 5QHI Target: FAM83BA Deposited: 18/05/2018 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000271a Target Class: Cell Division Disease Areas: Cancer Site: Oxford Status: Follow-up not counted


	PDB: 5QHJ Target: FAM83BA Deposited: 18/05/2018 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000709a Target Class: Cell Division Disease Areas: Cancer Site: Oxford Status: Follow-up not counted


	PDB: 5QHK Target: FAM83BA Deposited: 18/05/2018 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000010a Target Class: Cell Division Disease Areas: Cancer Site: Oxford Status: Follow-up not counted


	PDB: 5QHO Target: FAM83BA Deposited: 18/05/2018 Crystal Structure of human FAM83B in complex with FMOPL000010a Target Class: Cell Division Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 5QHP Target: FAM83BA Deposited: 18/05/2018 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000554a Target Class: Cell Division Disease Areas: Cancer Site: Oxford Status: Follow-up not counted


	PDB: 5QHQ Target: FAM83BA Deposited: 18/05/2018 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000574a Target Class: Cell Division Disease Areas: Cancer Site: Oxford Status: Follow-up not counted


	PDB: 5QHR Target: FAM83BA Deposited: 18/05/2018 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000635a Target Class: Cell Division Disease Areas: Cancer Site: Oxford Status: Follow-up not counted


	PDB: 6GIN Target: ACVR1A Deposited: 14/05/2018 Crystal structure of the ACVR1 (ALK2) kinase in complex with an Quinazolinone based ALK2 inhibitor with a 4-morpholinophenyl solvent accessible group. Target Class: Protein Kinase/TKL Disease Areas: Site: Oxford Status:


	PDB: 6GIP Target: ACVR1A Deposited: 14/05/2018 Crystal structure of the ACVR1 (ALK2) kinase in complex with a Quinazolinone based ALK2 inhibitor with a 2, 5-dimethyl core. Target Class: Protein Kinase/TKL Disease Areas: Site: Oxford Status:


	PDB: 6GES Target: MAPK3A Deposited: 27/04/2018 Crystal structure of ERK1 covalently bound to SM1-71 Target Class: Protein Kinase/CMGC Disease Areas: Signalling and cancer Site: Frankfurt Status: Follow-up not counted


	PDB: 6D1T Target: MBD1 Deposited: 12/04/2018 Human methyl-CpG binding domain protein 1, MBD domain, in complex with methylated DNA Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 6CVZ Target: RFWD3 Deposited: 29/03/2018 Human ring finger and WD repeat domain 3, WDR domain Target Class: WDR Disease Areas: Signalling and cancer Site: Toronto Status: Official


	PDB: 6G54 Target: MAPK1A Deposited: 29/03/2018 Crystal structure of ERK2 covalently bound to SM1-71 Target Class: Protein Kinase/CMGC Disease Areas: Signalling and cancer Site: Frankfurt Status: Follow-up not counted


	PDB: 6CW0 Target: PP-BRD13 Deposited: 29/03/2018 Cryptosporidium parvum bromodomain containing protein 13 (cgd2_2690), in complex with inhibitor BI-2536 Target Class: Bromodomain Disease Areas: Parasitic disease Site: Status: Counted


	PDB: 6D2L Target: CARM1 Deposited: 29/03/2018 Human coactivator associated arginine methyltransferase 1, methyltransferase domain, in complex with inhibitor (S)-SKI-72 Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 6CCG Target: MBD3 Deposited: 29/03/2018 Human methyl-CpG binding domain protein 3, MBD domain, in complex with methylated CpG DNA Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6G5N Target: SP100A Deposited: 29/03/2018 Crystal structure of human SP100 in complex with bromodomain-focused fragment XS039818e 1-(3-Phenyl-1,2,4-oxadiazol-5-yl)methanamine Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 6G57 Target: KCTD8A Deposited: 29/03/2018 Structure of the H1 domain of human KCTD8 Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Site: Oxford Status: Official


	PDB: 6G5P Target: SP100A Deposited: 29/03/2018 Crystal structure of human SP100 in complex with bromodomain-focused fragment FM009493b 2,3-Dimethoxy-2,3-dimethyl-2,3-dihydro-1,4-benzodioxin-6-amine Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 6G4Q Target: XX01SUCLG1A Deposited: 28/03/2018 Structure of human ADP-forming succinyl-CoA ligase complex SUCLG1-SUCLA2 Target Class: Disease Areas: Site: Oxford Status: Official


	PDB: 6CUI Target: BRD2 Deposited: 28/03/2018 Human bromodomain-containing protein 2, Extraterminal (ET) Domain Target Class: Bromodomain Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6G0O Target: BRD4A Deposited: 19/03/2018 Crystal Structure of the first bromodomain of human BRD4 in complex with an acetylated ATRX peptide (K1030ac/K1033ac) Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6G0P Target: BRD4A Deposited: 19/03/2018 Crystal Structure of the first bromodomain of human BRD4 in complex with an acetylated E2F1 peptide (K117ac/K120ac) Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6G0Q Target: BRD4A Deposited: 19/03/2018 Crystal Structure of the first bromodomain of human BRD4 in complex with an acetylated GATA1 peptide (K312ac/K315ac) Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6G0R Target: BRD4A Deposited: 19/03/2018 Crystal Structure of the first bromodomain of human BRD4 in complex with an acetylated POLR2A peptide (K775ac/K778ac) Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6G0S Target: BRD4A Deposited: 19/03/2018 Crystal Structure of the first bromodomain of human BRD4 in complex with an acetylated SIRT7 peptide (K272ac/K275ac) Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up not counted


	PDB: 6CNP Target: MBD2 Deposited: 08/03/2018 Human methyl-CpG binding domain protein 2, MBD domain, in complex with CpG island Target Class: Miscellaneous Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6FWZ Target: DPAGT1A Deposited: 07/03/2018 Crystal structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) (V264G mutant) in complex with UDP-GlcNAc Target Class: Membrane proteins Disease Areas: Neurobiology Site: Oxford Status: Follow-up official


	PDB: 6FU5 Target: RIPK2 Deposited: 28/02/2018 Human receptor interacting serine/threonine kinase 2 Target Class: Protein Kinase/TKL Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6CKN Target: MLLT10 Deposited: 28/02/2018 Human histone methyltransferase cofactor AF-10, OM-LZ domain Target Class: Miscellaneous Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6CKO Target: MLLT10 - DOT1L Deposited: 28/02/2018 Human histone methyltransferase cofactor AF-10, OM-LZ domain, in complex with DOT1L coiled-coil domain Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 5QHL Target: FAM83BA Deposited: 18/02/2018 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000551a Target Class: Cell Division Disease Areas: Cancer Site: Oxford Status: Follow-up not counted


	PDB: 6CDG Target: GID4 Deposited: 08/02/2018 Human glucose-induced degradation protein 4 homolog, substrate binding domain, in complex with substrate peptide PGLWKS Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Signalling and metabolism Site: Toronto Status: Counted


	PDB: 6CCR Target: GID4 Deposited: 07/02/2018 Human glucose-induced degradation protein 4 homolog, substrate binding domain Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Signalling and metabolism Site: Toronto Status: Counted


	PDB: 6CC8 Target: MBD3 Deposited: 06/02/2018 Human methyl-CpG binding domain protein 3, MBD domain, in complex with methylated CpG DNA Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Counted


	PDB: 6C1T Target: MBD2 Deposited: 05/01/2018 Human methyl-CpG binding domain protein 2, MBD domain, in complex with partially methylated DNA Target Class: Miscellaneous Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6C1V Target: MBD2 Deposited: 05/01/2018 Human methyl-CpG binding domain protein 2, MBD domain, in complex with double-stranded DNA Target Class: Miscellaneous Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6C1A Target: MBD2 Deposited: 04/01/2018 Human methyl-CpG binding domain protein 2, MBD domain, in complex with methylated DNA Target Class: Miscellaneous Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6FDY Target: ULK3 Deposited: 31/12/2017 Human unc-51 like kinase 3 Target Class: Protein Kinase/Other Disease Areas: Cancer Site: Oxford Status: Counted


	PDB: 6FDZ Target: ULK3 Deposited: 31/12/2017 Human unc-51 like kinase 3 Target Class: Protein Kinase/Other Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 6FCX Target: MTHFRA Deposited: 21/12/2017 Structure of human 5,10-methylenetetrahydrofolate reductase (MTHFR) Target Class: Disease Areas: Site: Oxford Status: Official


	PDB: 6BYA Target: PP-BRD3 Deposited: 20/12/2017 Leishmania donovani bromodomain containing 3 (LdBPK_091320), bromodomain, in complex with inhibitor SGC-CBP30 Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Follow-up official


	PDB: 6BY9 Target: EHMT1 Deposited: 20/12/2017 Human euchromatic histone lysine methyltransferase 1, ankyrin repeat Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Counted


	PDB: 6BYB Target: L3MBTL1 Deposited: 20/12/2017 Human L3MBTL1, histone methyl-lysine binding protein, MBT domains, in complex with inhibitor MBK14970 Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: MedChem


	PDB: 6FBK Target: WNK2A Deposited: 19/12/2017 Crystal structure of the human WNK2 CCT-like 1 domain in complex with a WNK1 RFXV peptide Target Class: Protein Kinase/Other Disease Areas: Site: Oxford Status:


	PDB: 6BW3 Target: RBBP4 Deposited: 14/12/2017 Human RB binding protein 4, chromatin remodeling factor, WDR domain, in complex with PRDM3 peptide Target Class: WDR Disease Areas: Cancer and epigenetics Site: Status: Follow-up official


	PDB: 6BW4 Target: RBBP4 Deposited: 14/12/2017 Human RB binding protein 4, chromatin remodeling factor, WDR domain, in complex with PRDM16 peptide Target Class: WDR Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 6BPI Target: SETDB1 Deposited: 23/11/2017 Human histone-lysine N-methyltransferase SETDB1, triple Tudor domain, in complex with aryl triazole fragment peptide conjugate Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 6EI2 Target: B2MA Deposited: 10/11/2017 Crystal Structure of HLA-A68 presenting a C-terminally extended peptide Target Class: Disease Areas: Site: Oxford Status:


	PDB: 6BHD Target: SETDB1 Deposited: 30/10/2017 Human histone-lysine N-methyltransferase SETDB1, triple Tudor domain, in complex with H3K9me2K14ac peptide Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6BHI Target: SETDB1 Deposited: 30/10/2017 Human histone-lysine N-methyltransferase SETDB1 W358A, triple Tudor domain, in complex with H3K9me3K14ac peptide Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 6BHH Target: SETDB1 Deposited: 30/10/2017 Human histone-lysine N-methyltransferase SETDB1 W358A, triple Tudor domain, in complex with H3K9me2K14ac peptide Target Class: Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 6BHE Target: SETDB1 Deposited: 30/10/2017 Human histone-lysine N-methyltransferase SETDB1, triple Tudor domain, in complex with H3K9me3K14ac peptide Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 6BHG Target: SETDB1 Deposited: 30/10/2017 Human histone-lysine N-methyltransferase SETDB1, triple Tudor domain, in complex with H3K14ac peptide Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 6ES0 Target: RIPK2A Deposited: 19/10/2017 Crystal structure of the kinase domain of human RIPK2 in complex with the activation loop targeting inhibitor CS-R35 Target Class: Kinase-Other Disease Areas: Site: Oxford Status:


	PDB: 6EIM Target: STK10 Deposited: 18/10/2017 Human serine/threonine kinase 10 Target Class: Protein Kinase/STE Disease Areas: Cancer Site: Oxford Status: MedChem


	PDB: 6ASB Target: FBXL19 Deposited: 30/09/2017 Human F-box/LRR-repeat protein 19, CXXC and PHD finger domains, in complex with DNA Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Signalling and epigenetics Site: Toronto Status: Counted


	PDB: 6EL8 Target: FOXN1A Deposited: 29/09/2017 Human transcription factor [Homo sapiens] Target Class: Disease Areas: Site: Oxford Status:


	PDB: 6ELM Target: WNK2A Deposited: 29/09/2017 Human WNK lysine deficient protein kinase 2 Target Class: Protein Kinase/Other Disease Areas: Site: Oxford Status:


	PDB: 6EIN Target: JARID1BA Deposited: 29/09/2017 Human lysine demethylase 5B Target Class: Demethylase/Methyl-Lysine Reader, PHD domain Disease Areas: Cancer Site: Oxford Status:


	PDB: 6EIU Target: JARID1BA Deposited: 29/09/2017 Human lysine demethylase 5B Target Class: Demethylase/Methyl-Lysine Reader, PHD domain Disease Areas: Cancer Site: Oxford Status:


	PDB: 6EIY Target: JARID1BA Deposited: 29/09/2017 Human lysine demethylase 5B Target Class: Demethylase/Methyl-Lysine Reader, PHD domain Disease Areas: Cancer Site: Oxford Status:


	PDB: 6EJ0 Target: JARID1BA Deposited: 29/09/2017 Human lysine demethylase 5B Target Class: Demethylase/Methyl-Lysine Reader, PHD domain Disease Areas: Cancer Site: Oxford Status:


	PDB: 6EJ1 Target: JARID1BA Deposited: 29/09/2017 Human lysine demethylase 5B Target Class: Demethylase/Methyl-Lysine Reader, PHD domain Disease Areas: Cancer Site: Oxford Status:


	PDB: 6B57 Target: TDRD2 Deposited: 29/09/2017 Human Tudor and KH domain-containing protein, extended Tudor domain, in complex with glycine-arginine rich peptide Target Class: Methyl-lysine readers Disease Areas: Signalling and cancer Site: Toronto Status: Follow-up official


	PDB: 6EK6 Target: JARID1BA Deposited: 29/09/2017 Human lysine demethylase 5B Target Class: Demethylase/Methyl-Lysine Reader, PHD domain Disease Areas: Cancer Site: Oxford Status:


	PDB: 6EKK Target: DENND1AA Deposited: 29/09/2017 Human DENN domain containing 1A Target Class: Disease Areas: Neurobiology Site: Oxford Status: Official


	PDB: 6AU2 Target: SETDB1 Deposited: 28/09/2017 Human histone-lysine N-methyltransferase SETDB1, triple Tudor domain, in complex with aryl triazole fragment Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Status: Follow-up not counted


	PDB: 6AU3 Target: SETDB1 Deposited: 28/09/2017 Human histone-lysine N-methyltransferase SETDB1, triple Tudor domain, in complex with aryl triazole fragment Target Class: Methyl-lysine readers Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 6ASD Target: TET1 Deposited: 28/09/2017 Human methylcytosine dioxygenase TET1, CXXC domain, in complex with DNA Target Class: Miscellaneous Disease Areas: Cancer and epigenetics Site: Toronto Status: Counted


	PDB: 6EIX Target: ACVR1Z Deposited: 19/09/2017 Mouse activin A receptor type 1 Target Class: Protein Kinase/TKL Disease Areas: Site: Oxford Status:


	PDB: 5OY6 Target: ACVR1A Deposited: 08/09/2017 Human activin A receptor type 1 Target Class: Protein Kinase/TKL Disease Areas: Site: Oxford Status:


	PDB: 5OXG Target: ACVR1A Deposited: 07/09/2017 Human activin A receptor type 1 Target Class: Protein Kinase/TKL Disease Areas: Site: Oxford Status:


	PDB: 5YBJ Target: KANK1 Deposited: 05/09/2017 Human KN motif and ankyrin repeat domains 1, ankyrin repeat Target Class: Miscellaneous Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 5YBU Target: KANK1 Deposited: 05/09/2017 Human KN motif and ankyrin repeat domains 1, ankyrin repeat, in complex with KIF21A peptide Target Class: Miscellaneous Disease Areas: Cancer Site: Toronto Status: Counted


	PDB: 5YBV Target: KANK2 Deposited: 05/09/2017 Human KN motif and ankyrin repeat domains 2, ankyrin repeat, in complex with KIF21A peptide Target Class: Miscellaneous Disease Areas: Cancer Site: Toronto Status: Follow-up not counted


	PDB: 5OWQ Target: STK10A Deposited: 03/09/2017 Human serine/threonine kinase 10 Target Class: Protein Kinase/STE Disease Areas: Site: Oxford Status:


	PDB: 5OWR Target: STK10A Deposited: 03/09/2017 Human serine/threonine kinase 10 Target Class: Protein Kinase/STE Disease Areas: Site: Oxford Status:


	PDB: 5WP3 Target: EED Deposited: 03/08/2017 Human Polycomb protein EED, in complex with EB22 Target Class: WDR Disease Areas: Cancer and epigenetics Site: Status: Follow-up official


	PDB: 5OCN Target: FOXN1A Deposited: 03/07/2017 Human transcription factor [Homo sapiens] Target Class: Disease Areas: Site: Oxford Status: Official


	PDB: 5W9S Target: CXXC5 Deposited: 30/06/2017 Human CXXC-type zinc finger protein 5, CXXC domain, in complex with DNA Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Counted


	PDB: 5W9Q Target: MBD1 Deposited: 30/06/2017 Human Methyl-CpG-binding domain protein 1, 3rd CXXC domain, in complex with DNA Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Official


	PDB: 5WBV Target: SUV420H1 Deposited: 30/06/2017 Human Histone-lysine N-methyltransferase KMT5B (SUV420H1), catalytic domain, in complex with inhibitor Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: Follow-up official


	PDB: 5WCJ Target: METTL13 Deposited: 30/06/2017 Human Methyltransferase-like protein 13, C-term catalytic domain, in complex with cofactor Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Counted


	PDB: 5WCI Target: MYST1 Deposited: 30/06/2017 Human histone acetyltransferase KAT8 (MYST1), catalytic domain, in complex with propionyl-coA Target Class: Transferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5WCG Target: SMYD2 Deposited: 30/06/2017 Human N-lysine methyltransferase SMYD2, full length, in complex with bi-subtrate inhibitor Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: MedChem


	PDB: 5OCH Target: ABCB8A Deposited: 30/06/2017 Human ATP binding cassette subfamily B member 8 Target Class: IMP/ABC Transporter Disease Areas: Metabolism Site: Oxford Status: Official


	PDB: 5WBN Target: HDAC6 Deposited: 30/06/2017 Human histone deacetylase 6, ZnF ubiquitin-binding domain, in complex with inhibitor Target Class: Transferases, Ubiquitin Related Biology Disease Areas: Cancer Site: Toronto Status: Follow-up official


	PDB: 5WCF Target: HRMT1L6 Deposited: 29/06/2017 Human protein arginine methyltransferase 6, catalytic domain, in complex with inhibitor Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 5OC9 Target: TMEM16KA Deposited: 29/06/2017 Human anoctamin 10 Target Class: IMP/Channel-Cl Disease Areas: Signalling Site: Oxford Status: Official


	PDB: 5W9R Target: PP-CDPK4 Deposited: 23/06/2017 Toxplasma gondii calmodulin-domain protein kinase 1 in complex with inhibitor LJQ138 Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up not counted


	PDB: 5W9E Target: PP-CDPK4 Deposited: 23/06/2017 Toxplasma gondii calmodulin-domain protein kinase 1 in complex with inhibitor GXJ-186 Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up not counted


	PDB: 5W91 Target: PP-CDPK4 Deposited: 22/06/2017 Toxplasma gondii calmodulin-domain protein kinase 1 in complex with inhibitor LZH-118 Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up not counted


	PDB: 5W8R Target: PP-CDPK4 Deposited: 22/06/2017 Toxplasma gondii calmodulin-domain protein kinase 1 in complex with inhibitor 3CIB-PPI Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up not counted


	PDB: 5W80 Target: PP-CDPK4 Deposited: 21/06/2017 Toxplasma gondii calmodulin-domain protein kinase 1 in complex with inhibitor GXJ-237 Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Status: Follow-up official


	PDB: 5W1Y Target: SETD8 Deposited: 05/06/2017 Human N-lysine methyltransferase KMT5A in complex with a covalent inhibitor Target Class: Methyltransferases Disease Areas: Cancer and epigenetics Site: Toronto Status: MedChem


	PDB: 5NZW Target: DCLRE1AA Deposited: 02/06/2017 Human DNA cross-link repair 1A Target Class: RNA/DNA Processing/DNA-Repair Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5NZX Target: DCLRE1AA Deposited: 02/06/2017 Human DNA cross-link repair 1A Target Class: RNA/DNA Processing/DNA-Repair Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5NZY Target: DCLRE1AA Deposited: 02/06/2017 Human DNA cross-link repair 1A Target Class: RNA/DNA Processing/DNA-Repair Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5O5E Target: DPAGT1A Deposited: 01/06/2017 Human dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 Target Class: IMP/Enzyme Disease Areas: Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5NXC Target: LIMK1A Deposited: 25/05/2017 Human LIM domain kinase 1 Target Class: Protein Kinase/TKL Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5NXD Target: LIMK2A Deposited: 25/05/2017 Human LIM domain kinase 2 Target Class: Protein Kinase/TKL Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5O33 Target: XX02KALRNA Deposited: 24/05/2017 Human A structure of the GEF Kalirin DH1 domain in complex with the small GTPase Rac1 Target Class: Disease Areas: Signalling Site: Oxford Status: Official


	PDB: 5O2C Target: WNK3B Deposited: 20/05/2017 Human WNK lysine deficient protein kinase 3 Target Class: Protein Kinase/Other Disease Areas: Signalling Site: Oxford Status: Official


	PDB: 5O1V Target: WNK3B Deposited: 20/05/2017 Human WNK lysine deficient protein kinase 3 Target Class: Protein Kinase/Other Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5O21 Target: WNK3B Deposited: 20/05/2017 Human WNK lysine deficient protein kinase 3 Target Class: Protein Kinase/Other Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5O23 Target: WNK3B Deposited: 20/05/2017 Human WNK lysine deficient protein kinase 3 Target Class: Protein Kinase/Other Disease Areas: Signalling Site: Oxford Status: Official


	PDB: 5O26 Target: WNK3B Deposited: 20/05/2017 Human WNK lysine deficient protein kinase 3 Target Class: Protein Kinase/Other Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5O2B Target: WNK3B Deposited: 20/05/2017 Human WNK lysine deficient protein kinase 3 Target Class: Protein Kinase/Other Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5O2D Target: PARP14A Deposited: 20/05/2017 Human poly(ADP-ribose) polymerase family member 14 Target Class: Disease Areas: Metabolism Site: Oxford Status: Official


	PDB: 5O1O Target: AASSA Deposited: 19/05/2017 Human aminoadipate-semialdehyde synthase Target Class: Oxidoreductases Disease Areas: Metabolism Site: Oxford Status: Follow-up official


	PDB: 5O1P Target: AASSA Deposited: 19/05/2017 Human aminoadipate-semialdehyde synthase Target Class: Oxidoreductases Disease Areas: Metabolism Site: Oxford Status: Follow-up official


	PDB: 5O1N Target: AASSA Deposited: 19/05/2017 Human aminoadipate-semialdehyde synthase Target Class: Oxidoreductases Disease Areas: Metabolism Site: Oxford Status: Follow-up official


	PDB: 5VS7 Target: PP-BRD4 Deposited: 11/05/2017 Plasmodium falciparum bromodomain protein 3 (PF3D7_1475600), bromodomain, in complex with H4K5ac peptide Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Follow-up official


	PDB: 5NNC Target: BRD4 Deposited: 19/04/2017 Human bromodomain containing 4 Target Class: Bromodomain Disease Areas: Cancer and epigenetics Site: Oxford Status: MedChem


	PDB: 5NND Target: BRD4 Deposited: 19/04/2017 Human bromodomain containing 4 Target Class: Bromodomain Disease Areas: Cancer and epigenetics Site: Oxford Status: MedChem


	PDB: 5NNE Target: BRD4 Deposited: 19/04/2017 Human bromodomain containing 4 Target Class: Bromodomain Disease Areas: Cancer and epigenetics Site: Oxford Status: MedChem


	PDB: 5NNF Target: BRD4 Deposited: 19/04/2017 Human bromodomain containing 4 Target Class: Bromodomain Disease Areas: Cancer and epigenetics Site: Oxford Status: MedChem


	PDB: 5NNG Target: BRD4 Deposited: 19/04/2017 Human bromodomain containing 4 Target Class: Bromodomain Disease Areas: Cancer and epigenetics Site: Oxford Status: MedChem


	PDB: 5NKP Target: KLHL3A Deposited: 31/03/2017 Human kelch like family member 3 (KLHL3) in complex with WNK3 peptide Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Metabolism Site: Oxford Status: Follow-up official


	PDB: 5NKS Target: DPYSL4A Deposited: 31/03/2017 Human dihydropyrimidinase like 4 Target Class: Disease Areas: Neurobiology Site: Oxford Status: Official


	PDB: 5NLB Target: XX09KEAP1A Deposited: 31/03/2017 5NLB Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Metabolism Site: Oxford Status: Official


	PDB: 5VC9 Target: CXXC4 Deposited: 29/03/2017 CXXC finger protein 4, Zinc finger, in complex with ACGT DNA Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Official


	PDB: 5VC8 Target: WHSC1 Deposited: 29/03/2017 Human nuclear receptor binding SET domain protein 2, first PWWP domain Target Class: Methyl-lysine readers Disease Areas: Cancer Site: Toronto Status: Official


	PDB: 5VBT Target: UBC Deposited: 29/03/2017 Human ubiquitin variant UBH04 Target Class: Ubiquitin Related Biology Disease Areas: Signalling Site: Toronto Status: Follow-up official


	PDB: 5VBB Target: RPUSD1 Deposited: 28/03/2017 Human RNA pseudouridylate synthase domain containing 1, catalytic domain Target Class: Oxidoreductases Disease Areas: Signalling Site: Toronto Status: Official


	PDB: 5VBD Target: USP09X Deposited: 28/03/2017 Human ubiquitin specific peptidase 9, X-linked, ubiquitin-like domain Target Class: Deubiquitinating Enzymes - USP, Ubiquitin Related Biology Disease Areas: Signalling Site: Toronto Status: Official


	PDB: 5V9I Target: BAT8 Deposited: 23/03/2017 Human euchromatic histone lysine methyltransferase 2, catalytic domain, in complex with inhibitor UNC3644 Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5V9J Target: EHMT1 Deposited: 23/03/2017 Human euchromatic histone lysine methyltransferase 1, catalytic domain, in complex with inhibitor MS0105 Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5NFJ Target: RG9MTD1A Deposited: 14/03/2017 Human tRNA methyltransferase 10C, mitochondrial RNase P subunit Target Class: Metabolic enzymes/Other Disease Areas: Metabolism Site: Oxford Status: Official


	PDB: 5MXX Target: SRPK1A Deposited: 07/02/2017 Human SRSF protein kinase 1 Target Class: Protein Kinase/CMGC Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5MYG Target: BRPF1B Deposited: 07/02/2017 Human bromodomain and PHD finger containing 1 Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up not counted


	PDB: 5N2L Target: BRD2A Deposited: 07/02/2017 Human bromodomain containing 2 Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5MYV Target: SRPK2A Deposited: 29/01/2017 Human SRSF protein kinase 2 Target Class: Protein Kinase/CMGC Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5MY8 Target: SRPK1A Deposited: 25/01/2017 Human SRSF protein kinase 1 Target Class: Protein Kinase/CMGC Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5ULO Target: YWHAZ Deposited: 25/01/2017 Human tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta, in complex with a TBC1D7 phosphopeptide Target Class: Signalling proteins Disease Areas: Metabolism Site: Toronto Status: Follow-up official


	PDB: 5MUF Target: PGAM5A Deposited: 13/01/2017 Human PGAM family member 5, mitochondrial serine/threonine protein phosphatase Target Class: Phosphatases Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5UBA Target: RPUSD4 Deposited: 30/12/2016 Human RNA pseudouridylate synthase domain containing 4, catalytic domain Target Class: Transferases Disease Areas: Chromatin and epigenetics, Signalling Site: Toronto Status: Pending-Official Structure


	PDB: 5UBB Target: LOC149281 Deposited: 30/12/2016 Human methyltransferase like 11B (a.k.a NTM1B), catalytic domain, in complex with cofactor SAM Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics, Signalling Site: Toronto Status: Pending-Official Structure


	PDB: 5MR8 Target: TRIM33B Deposited: 28/12/2016 Human tripartite motif containing 33 Target Class: Bromodomain, Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Official


	PDB: 5MR1 Target: PIP3EA Deposited: 21/12/2016 Human interaction protein for cytohesin exchange factors 1 Target Class: Miscellaneous Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5MQ4 Target: PRKCBP1A Deposited: 20/12/2016 Human zinc finger MYND-type containing 8 Target Class: Protein Kinase Disease Areas: Cancer Site: Oxford Status: Pending-Official Structure


	PDB: 5MQ1 Target: BRD7A Deposited: 19/12/2016 Human bromodomain containing 7 Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5MPO Target: XX02MOCS2A Deposited: 16/12/2016 Human molybdenum cofactor synthesis 2 Target Class: Miscellaneous Disease Areas: Neurobiology Site: Oxford Status: Pending-Official Structure


	PDB: 5U9N Target: PP-BRD3 Deposited: 16/12/2016 Cryptosporidium parvum cdg4_1340, second bromodomain, in complex with bromosporine Target Class: Bromodomain Disease Areas: Chromatin and epigenetics, Parasitic disease Site: Toronto Status: Pending-Official Structure


	PDB: 5MP0 Target: DCP2B Deposited: 15/12/2016 Human decapping mRNA 2 Target Class: NUDIX Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5MLE Target: DPYSL2A Deposited: 06/12/2016 Human dihydropyrimidinase like 2 Target Class: Miscellaneous Disease Areas: Neurobiology Site: Oxford Status: Pending-Official Structure


	PDB: 5U4X Target: CARM1 Deposited: 06/12/2016 Human coactivator associated arginine methyltransferase 1, catalytic domain, in complex with chemical probe TP-064 Target Class: Methyltransferases Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: MedChem


	PDB: 5MKV Target: DPYSL2A Deposited: 05/12/2016 Human dihydropyrimidinase like 2 Target Class: Miscellaneous Disease Areas: Neurobiology Site: Oxford Status: Pending-Official Structure


	PDB: 5MG2 Target: TAF1A Deposited: 20/11/2016 Human TATA-box binding protein associated factor 1 Target Class: Bromodomain Disease Areas: Cancer, Signalling Site: Oxford Status: Follow-up official


	PDB: 5TB6 Target: CREBBP Deposited: 09/11/2016 Human CREB binding protein isoform a Target Class: Bromodomain Disease Areas: Cancer, Metabolism, Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5TTW Target: EED Deposited: 04/11/2016 Human embryonic ectoderm development, WDR domain, in complex with peptoid inhibitor UNC4859 Target Class: WDR Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: MedChem


	PDB: 5TTF Target: BAT8 Deposited: 03/11/2016 Human euchromatic histone lysine methyltransferase 2, catalytic domain, in complex with inhibitor MS012 Target Class: Methyltransferases Disease Areas: Cancer, Chromatin and epigenetics, Neurobiology Site: Toronto Status: Follow-up not counted


	PDB: 5TTG Target: EHMT1 Deposited: 03/11/2016 Human euchromatic histone lysine methyltransferase 1, catalytic domain, in complex with inhibitor MS012 Target Class: Methyltransferases Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5M9N Target: TDRD1A Deposited: 01/11/2016 Human tudor domain containing 1 Target Class: Methyl-lysine readers Disease Areas: Site: Oxford Status: Pending-Official Structure


	PDB: 5M9O Target: SND1A Deposited: 01/11/2016 Human staphylococcal nuclease and tudor domain containing 1 Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5TPX Target: PF08_0034 Deposited: 24/10/2016 Plasmodium falciparum histone acetyltransferase GCN5, bromodomain, in complex with inhibitor L-45/L-Moses Target Class: Bromodomain Disease Areas: Chromatin and epigenetics, Parasitic disease Site: Toronto Status: Follow-up official


	PDB: 5T4U Target: BRPF1B Deposited: 01/10/2016 Human bromodomain and PHD finger containing 1 Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5T4V Target: BRPF1B Deposited: 01/10/2016 Human bromodomain and PHD finger containing 1 Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5TH7 Target: SETD8 Deposited: 30/09/2016 Human SET domain containing (lysine methyltransferase) 8, SET domain, in complex with covalent inhibitor MS453 Target Class: Methyltransferases Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: MedChem


	PDB: 5TEY Target: METTL3-METTL14 Deposited: 30/09/2016 Human methyltransferase like 3 - 14 dimer in complex with cofactor Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5LZK Target: FAM83BA Deposited: 29/09/2016 Human family with sequence similarity 83 member B Target Class: Cell Division Disease Areas: Cancer Site: Oxford Status: Pending-Official Structure


	PDB: 5GXH Target: GEMIN5 Deposited: 25/09/2016 Human gem nuclear organelle associated protein 5, WD40 domain, in complex with AAUUUUUG RNA Target Class: WDR Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5GXI Target: GEMIN5 Deposited: 25/09/2016 Human gem nuclear organelle associated protein 5, WD40 domain, in complex with AAUUUUUGAG RNA Target Class: WDR Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 5TEE Target: GEMIN5 Deposited: 23/09/2016 Human gem nuclear organelle associated protein 5, WD40 domain Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Pending-Official Structure


	PDB: 5TEF Target: GEMIN5 Deposited: 23/09/2016 Human gem nuclear organelle associated protein 5, WD40 domain, in complex with m7GpppG Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 5TF2 Target: PREB Deposited: 23/09/2016 Human prolactin regulatory element binding protein, WD40 domain Target Class: Miscellaneous Disease Areas: Neurobiology Site: Toronto Status: Pending - Official structure


	PDB: 5THA Target: GEMIN5 Deposited: 23/09/2016 Human gem nuclear organelle associated protein 5, WD40 domain, in complex with GTP Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5LXC Target: DYRK2A Deposited: 20/09/2016 Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 [isoform 1] Target Class: Protein Kinase Disease Areas: Cancer, Metabolism, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5LXD Target: DYRK2A Deposited: 20/09/2016 Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 [isoform 1] Target Class: Protein Kinase Disease Areas: Cancer, Metabolism, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5LWN Target: JAK3A Deposited: 18/09/2016 Human Janus kinase 3 (a protein tyrosine kinase, leukocyte) Target Class: Protein Kinase Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5LWM Target: JAK3A Deposited: 18/09/2016 Human Janus kinase 3 (a protein tyrosine kinase, leukocyte) Target Class: Protein Kinase Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5LTU Target: NUDT4A Deposited: 16/09/2016 Human nudix hydrolase 4 Target Class: NUDIX Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5TCM Target: PP-BRD3 Deposited: 15/09/2016 Leishmania donovani LdBPK.091320, first bromodomain, in complex with BI-2536 Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Pending-Official Structure


	PDB: 5LW9 Target: JARID1BA Deposited: 15/09/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5TCK Target: PP-BRD3 Deposited: 15/09/2016 Leishmania donovani LdBPK.091320, second bromodomain, in complex with Bromosporine Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Pending-Official Structure


	PDB: 5LVQ Target: PCAFA Deposited: 14/09/2016 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5LVR Target: PCAFA Deposited: 14/09/2016 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5LUU Target: BRD4A Deposited: 11/09/2016 Human bromodomain containing 4 [isoform long] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5LUG Target: SPIN2BA Deposited: 09/09/2016 Human spindlin family member 2B Target Class: Chromatin Regulation Disease Areas: Chromatin and epigenetics Site: Oxford Status: Pending-Official Structure


	PDB: 5T5G Target: SETD8 Deposited: 30/08/2016 Human SET domain containing (lysine methyltransferase) 8, SET domain, in complex with inhibitor MS2177 Target Class: Methyltransferases Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: MedChem


	PDB: 5T3P Target: NUDT7A Deposited: 26/08/2016 Human nudix hydrolase 7 Target Class: NUDIX Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5T1G Target: CBX1 Deposited: 19/08/2016 Human chromobox 1, chromoshadow domain, in complex with a histone 3 peptide Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5T1I Target: CBX3 Deposited: 19/08/2016 Human chromobox 3, chromoshadow domain, in complex with a histone 3 peptide Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 5LF8 Target: NUDT17A Deposited: 30/06/2016 Human nudix (nucleoside diphosphate linked moiety X)-type motif 17 Target Class: Nucleotide metabolism, NUDIX Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5LEV Target: DPAGT1A Deposited: 30/06/2016 Human dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 Target Class: IMP/Enzyme Disease Areas: Metabolism Site: Oxford Status: Official


	PDB: 5KO4 Target: PP-BRD19 Deposited: 29/06/2016 Trypanosoma brucei bromodomain containing factor 1 (Tb427.10.8150), Bromodomain Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Pending - Official structure


	PDB: 5KO9 Target: tesst Deposited: 29/06/2016 Human 5-hydroxymethylcytosine (hmC) binding, ES cell-specific, SRAP domain Target Class: Miscellaneous Disease Areas: Site: Oxford Status: Pending - Official structure


	PDB: 5KKP Target: PUS7 Deposited: 22/06/2016 Human pseudouridylate synthase 7, catalytic domain Target Class: Transferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Pending - Official structure


	PDB: 5LB8 Target: RECQL5A Deposited: 15/06/2016 Human RecQ protein-like 5 [isoform 1] Target Class: DExD-DExH RNA helicases Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5LBA Target: RECQL5A Deposited: 15/06/2016 Human RecQ protein-like 5 [isoform 1] Target Class: DExD-DExH RNA helicases Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5LB3 Target: RECQL5A Deposited: 15/06/2016 Human RecQ protein-like 5 [isoform 1] Target Class: DExD-DExH RNA helicases Disease Areas: Cancer Site: Oxford Status: Pending-Official Structure


	PDB: 5LB5 Target: RECQL5A Deposited: 15/06/2016 Human RecQ protein-like 5 [isoform 1] Target Class: DExD-DExH RNA helicases Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5B8D Target: HDAC6 Deposited: 14/06/2016 Human histone deacetylase 6, Znf ubiquitin binding domain, in complex with x304 (N-(4-Methyl-1,3-thiazol-2-yl)propanamide) in secondary pocket Target Class: Transferases, Ubiquitin Related Biology Disease Areas: Cancer Site: Toronto Status: MedChem


	PDB: 5KH3 Target: HDAC6 Deposited: 14/06/2016 Human histone deacetylase 6, Znf ubiquitin binding domain, in complex with DAT94a (3-(5-Chloro-1,3-benzothiazol-2-yl)propanoic acid). Target Class: Ubiquitin Related Biology Disease Areas: Site: Toronto Status: MedChem


	PDB: 5KH6 Target: SETDB1 Deposited: 14/06/2016 Human SET domain bifurcated 1, triple Tudor domain, in complex with fragment x337 Target Class: Methyl-lysine readers Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Pending-Official Structure


	PDB: 5KH7 Target: HDAC6 Deposited: 14/06/2016 Human histone deacetylase 6, Znf ubiquitin binding domain, in complex with F1967-0912 (3-[6-Oxo-3-(3-pyridinyl)-1(6H)-pyridazinyl]propanoic acid) Target Class: Transferases, Ubiquitin Related Biology Disease Areas: Cancer Site: Toronto Status: MedChem


	PDB: 5KH9 Target: HDAC6 Deposited: 14/06/2016 Human histone deacetylase 6, Znf ubiquitin binding domain, in complex with x469 (5-[(4-Isopropylphenyl)amino]-6-methyl-1,2,4-triazin-3(2H)-one) Target Class: Transferases, Ubiquitin Related Biology Disease Areas: Cancer Site: Toronto Status: MedChem


	PDB: 5LAR Target: MAPK14A Deposited: 14/06/2016 Human mitogen-activated protein kinase 14 [isoform 1] Target Class: Protein Kinase Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5L76 Target: AASSA Deposited: 02/06/2016 Human aminoadipate-semialdehyde synthase Target Class: Oxidoreductases Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5L78 Target: AASSA Deposited: 02/06/2016 Human aminoadipate-semialdehyde synthase Target Class: Oxidoreductases Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5L6W Target: XX02LIMK1A Deposited: 31/05/2016 Human LIMK1-ATPgammaS-CFL1 Complex Target Class: Protein Kinase Disease Areas: Cancer Site: Oxford Status: Pending-Official Structure


	PDB: 5J0D Target: CREBBPA Deposited: 30/05/2016 Human CREB binding protein Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics Site: Oxford Status: Pending-Official Structure


	PDB: 5L4Q Target: AAK1A Deposited: 26/05/2016 Human AP2 associated kinase 1 Target Class: Protein Kinase Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5K47 Target: PKD2A Deposited: 20/05/2016 Human polycystic kidney disease 2 (autosomal dominant) Target Class: Membrane proteins Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5K29 Target: PP-BRD3 Deposited: 18/05/2016 Trypanosoma brucei bromodomain containing factor 5 (Tb427tmp.01.5000), Bromodomain Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Pending-Official Structure


	PDB: 5JUW Target: DOT1L Deposited: 10/05/2016 Human DOT1 like histone lysine methyltransferase in complex with cyano-deaza-SAH Target Class: Methyltransferases Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5G3Q Target: WNK1A Deposited: 29/04/2016 Human WNK lysine deficient protein kinase 1 Target Class: Protein Kinase/Other Disease Areas: Cancer Site: Oxford Status: Pending-Official Structure


	PDB: 5JN2 Target: PP-CDPK4 Deposited: 29/04/2016 Toxoplasma gondii calcium dependent protein kinase 1, kinase domain, in complex with inhibitor NVPACU106 Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up official


	PDB: 5JJW Target: SART3 Deposited: 25/04/2016 Human squamous cell carcinoma antigen recognized by T-cells 3, HAT (Half-A-TPR) repeat, in complex with USP15 DUSP-UBL domain Target Class: Miscellaneous Disease Areas: Cancer Site: Toronto Status: Pending-Official Structure


	PDB: 5JJX Target: SART3 Deposited: 25/04/2016 Human squamous cell carcinoma antigen recognized by T-cells 3, HAT (Half-A-TPR) repeat Target Class: Miscellaneous Disease Areas: Cancer Site: Toronto Status: Pending-Official Structure


	PDB: 5FY7 Target: UTYC Deposited: 03/04/2016 Human tetratricopeptide repeat protein isoform 3; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Target Class: Oxidoreductases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5J3U Target: PP-PKAR Deposited: 31/03/2016 Toxoplasma gondii protein kinase A (583.m05422), regulatory domain, in complex with cAMP Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Pending-Official Structure


	PDB: 5J1V Target: CLK1A Deposited: 30/03/2016 Human CDC-like kinase 1 Target Class: Protein Kinase Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5J1W Target: CLK1A Deposited: 30/03/2016 Human CDC-like kinase 1 Target Class: Protein Kinase Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5J39 Target: TDRD2 Deposited: 30/03/2016 Human tudor and KH domain containing, extended tudor domain Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: Pending-Official Structure


	PDB: 5J3E Target: THYN1 Deposited: 30/03/2016 Human thymocyte nuclear protein 1, EVE domain, in complex with 5-methylcytosine containing DNA Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Pending-Official Structure


	PDB: 5HES Target: ZAKA Deposited: 23/03/2016 Human sterile-alpha motif and leucine zipper containing kinase AZK Target Class: Protein Kinase Disease Areas: Signalling Site: Oxford Status: Pending-Official Structure


	PDB: 5FZO Target: JMJD1CA Deposited: 15/03/2016 Human jumonji domain containing 1C [isoform a] Target Class: Oxidoreductases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZI Target: JARID1BA Deposited: 14/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZK Target: JARID1BA Deposited: 14/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZL Target: JARID1BA Deposited: 14/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZM Target: JARID1BA Deposited: 14/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZC Target: JARID1BA Deposited: 14/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZE Target: JARID1BA Deposited: 14/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Pending-Official Structure


	PDB: 5FZF Target: JARID1BA Deposited: 14/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZG Target: JARID1BA Deposited: 14/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZH Target: JARID1BA Deposited: 14/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZB Target: JARID1BA Deposited: 13/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZD Target: JARID1BA Deposited: 13/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZ9 Target: JARID1BA Deposited: 12/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZA Target: JARID1BA Deposited: 12/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZ6 Target: JARID1BA Deposited: 11/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZ7 Target: JARID1BA Deposited: 11/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZ8 Target: JARID1BA Deposited: 11/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZ0 Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZ1 Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZ3 Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FZ4 Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FYS Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FYT Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FYU Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FYV Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FYY Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FYZ Target: JARID1BA Deposited: 10/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FYM Target: UTYC Deposited: 08/03/2016 Human tetratricopeptide repeat protein isoform 3; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5FYC Target: JMJD2AA Deposited: 07/03/2016 Human jumonji domain containing 2A Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FYH Target: JMJD2AA Deposited: 07/03/2016 Human jumonji domain containing 2A Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FYI Target: JMJD2AA Deposited: 07/03/2016 Human jumonji domain containing 2A Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5IN3 Target: GALTA Deposited: 07/03/2016 Human galactose-1-phosphate uridylyltransferase Target Class: Transferases Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5FYB Target: JARID1BA Deposited: 05/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FY4 Target: JARID1BA Deposited: 04/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FY5 Target: JARID1BA Deposited: 04/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FY8 Target: JMJD2AA Deposited: 04/03/2016 Human jumonji domain containing 2A Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FY9 Target: JARID1BA Deposited: 04/03/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FXV Target: UTYC Deposited: 03/03/2016 Human tetratricopeptide repeat protein isoform 3; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5FXW Target: UTYC Deposited: 03/03/2016 Human tetratricopeptide repeat protein isoform 3; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5FXX Target: UTYC Deposited: 03/03/2016 Human tetratricopeptide repeat protein isoform 3; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5FXZ Target: UTYC Deposited: 03/03/2016 Human tetratricopeptide repeat protein isoform 3; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5FY0 Target: UTYC Deposited: 03/03/2016 Human tetratricopeptide repeat protein isoform 3; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5FY1 Target: UTYC Deposited: 03/03/2016 Human tetratricopeptide repeat protein isoform 3; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5II1 Target: PB1A Deposited: 01/03/2016 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5II2 Target: PB1A Deposited: 01/03/2016 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5IID Target: PB1A Deposited: 01/03/2016 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5IGN Target: BRD9A Deposited: 28/02/2016 Human bromodomain containing 9 [isoform 1] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FWJ Target: JARID1CA Deposited: 17/02/2016 Human Jumonji/ARID domain-containing protein 1C Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5I3L Target: DPF3 Deposited: 10/02/2016 Human double PHD fingers 3, double PHD domain, in complex with H3K14ac peptide Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5HZM Target: HRMT1L6 Deposited: 02/02/2016 Human protein arginine methyltransferase 6 with putative Rme2 electron density Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5FUN Target: JARID1BA Deposited: 28/01/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FUP Target: JARID1BA Deposited: 28/01/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FV3 Target: JARID1BA Deposited: 28/01/2016 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5HRV Target: PB1A Deposited: 24/01/2016 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5HRW Target: PB1A Deposited: 24/01/2016 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5HRX Target: PB1A Deposited: 24/01/2016 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5H9M Target: SIAH2 Deposited: 28/12/2015 Human siah E3 ubiquitin protein ligase 2, TRAF-like substrate binding domain Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Signalling Site: Toronto Status: Official


	PDB: 5FH6 Target: PB1A Deposited: 21/12/2015 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5FH7 Target: PB1A Deposited: 21/12/2015 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5FH8 Target: PB1A Deposited: 21/12/2015 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5FPL Target: JARID1BA Deposited: 21/12/2015 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FPU Target: JARID1BA Deposited: 21/12/2015 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FPV Target: JMJD2AA Deposited: 21/12/2015 Human jumonji domain containing 2A Target Class: Methyltransferases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FG4 Target: BRPF1B Deposited: 20/12/2015 Human bromodomain and PHD finger-containing protein 1 [isoform 2] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FG5 Target: BRPF1B Deposited: 20/12/2015 Human bromodomain and PHD finger-containing protein 1 [isoform 2] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FG6 Target: BRD1A Deposited: 20/12/2015 Human bromodomain containing protein 1 Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FFV Target: BRPF1B Deposited: 19/12/2015 Human bromodomain and PHD finger-containing protein 1 [isoform 2] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FFW Target: BRPF1B Deposited: 19/12/2015 Human bromodomain and PHD finger-containing protein 1 [isoform 2] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FFY Target: BRPF1B Deposited: 19/12/2015 Human bromodomain and PHD finger-containing protein 1 [isoform 2] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5FDP Target: DDR1A Deposited: 16/12/2015 Human discoidin domain receptor family, member 1 isoform b Target Class: Protein Kinase Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5FDX Target: DDR1A Deposited: 16/12/2015 Human discoidin domain receptor family, member 1 isoform b Target Class: Protein Kinase Disease Areas: Signalling Site: Oxford Status: Follow-up official


	PDB: 5FDZ Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FE0 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FE1 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FE2 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FE3 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FE4 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FE5 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FE6 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FE7 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FE8 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FE9 Target: PCAFA Deposited: 16/12/2015 Human p300/CBP-associated factor Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5FEA Target: PP-BRD19 Deposited: 16/12/2015 Leishmania donovani bromodomain (LdBPK_363520.1), domain swapped, in complex with Bromosporine Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Pending-Official Structure


	PDB: 5FBX Target: BRD4A Deposited: 14/12/2015 Human bromodomain containing 4 [isoform long] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 5FAI Target: EMG1 Deposited: 11/12/2015 Human EMG1 N1-specific pseudouridine methyltransferase, catalytic domain, in complex with S-adenosyl homocysteine Target Class: Transferases Disease Areas: Signalling Site: Toronto Status: Pending-Official Structure


	PDB: 5F5A Target: JMJD2DA Deposited: 04/12/2015 Human jumonji domain containing 2D Target Class: Oxidoreductases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5F5C Target: JMJD2DA Deposited: 04/12/2015 Human jumonji domain containing 2D Target Class: Oxidoreductases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5F5I Target: JMJD2AA Deposited: 04/12/2015 Human jumonji domain containing 2A Target Class: Oxidoreductases Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5EQ0 Target: CBX8 Deposited: 12/11/2015 Human chromobox 8, chromodomain, in complex with inhibitor UNC3866 Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5EPJ Target: CBX7 Deposited: 11/11/2015 Human chromobox 7, chromodomain, in complex with inhibitor UNC3866 Target Class: Methyl-lysine readers Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5EPK Target: CBX2 Deposited: 11/11/2015 Human chromobox 2, chromodomain, in complex with inhibitor UNC3866 Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5EPL Target: CBX4 Deposited: 11/11/2015 Human chromobox 4, chromodomain, in complex with inhibitor UNC3866 Target Class: Methyl-lysine readers Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 5ENB Target: PHIPA Deposited: 09/11/2015 Human pleckstrin homology domain interacting protein Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5ENC Target: PHIPA Deposited: 09/11/2015 Human pleckstrin homology domain interacting protein Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5ENE Target: PHIPA Deposited: 09/11/2015 Human pleckstrin homology domain interacting protein Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5ENF Target: PHIPA Deposited: 09/11/2015 Human pleckstrin homology domain interacting protein Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5ENH Target: PHIPA Deposited: 09/11/2015 Human pleckstrin homology domain interacting protein Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5ENI Target: PHIPA Deposited: 09/11/2015 Human pleckstrin homology domain interacting protein Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5ENJ Target: PHIPA Deposited: 09/11/2015 Human pleckstrin homology domain interacting protein Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5EK9 Target: BRD2A Deposited: 03/11/2015 Human bromodomain containing 2 Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5EAR Target: WDR5 Deposited: 16/10/2015 Human WD repeat domain 5 in complex with chemical probe OICR-9429 analog 9d Target Class: Miscellaneous Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5EAL Target: WDR5 Deposited: 16/10/2015 Human WD repeat domain 5 in complex with chemical probe OICR-9429 analog 9h Target Class: Miscellaneous Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5EAM Target: WDR5 Deposited: 16/10/2015 Human WD repeat domain 5 in complex with chemical probe OICR-9429 analog 9o Target Class: Miscellaneous Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5EAP Target: WDR5 Deposited: 16/10/2015 Human WD repeat domain 5 in complex with chemical probe OICR-9429 analog 9e Target Class: Miscellaneous Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5E9V Target: BRD9A Deposited: 15/10/2015 Human bromodomain containing 9 [isoform 1] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5E8R Target: HRMT1L6 Deposited: 14/10/2015 Human protein arginine methyltransferase 6 in complex with chemical probe MS023 Target Class: Methyltransferases Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5E26 Target: PANK2 Deposited: 30/09/2015 Human pantothenate kinase 2, catalytic domain, in complex with pantothenate and adenosine diphosphate Target Class: Non-protein Kinase Disease Areas: Metabolism, Signalling Site: Toronto Status: Pending-Official Structure


	PDB: 5E1B Target: AD-003 Deposited: 30/09/2015 Human N-terminal Xaa-Pro-Lys N-methyltransferase 1, in complex with cofactor SAH and SPKRIA peptide substrate Target Class: Methyltransferases Disease Areas: Cancer Site: Toronto Status: Pending-Official Structure


	PDB: 5E1D Target: AD-003 Deposited: 30/09/2015 Human N-terminal Xaa-Pro-Lys N-methyltransferase 1, in complex with cofactor SAH and YPKRIA peptide substrate Target Class: Methyltransferases Disease Areas: Cancer Site: Toronto Status: Follow-up official


	PDB: 5E1M Target: AD-003 Deposited: 30/09/2015 Human N-terminal Xaa-Pro-Lys N-methyltransferase 1, in complex with cofactor SAH and PPKRIA peptide substrate Target Class: Methyltransferases Disease Areas: Cancer Site: Toronto Status: Follow-up not counted


	PDB: 5E1O Target: AD-003 Deposited: 30/09/2015 Human N-terminal Xaa-Pro-Lys N-methyltransferase 1, in complex with cofactor SAH and RPKRIA peptide substrate Target Class: Methyltransferases Disease Areas: Cancer Site: Toronto Status: Follow-up not counted


	PDB: 5E2A Target: AD-003 Deposited: 30/09/2015 Human N-terminal Xaa-Pro-Lys N-methyltransferase 1, in complex with cofactor SAH and SmePKRIA peptide substrate Target Class: Methyltransferases Disease Areas: Cancer Site: Toronto Status: Follow-up not counted


	PDB: 5E2B Target: AD-003 Deposited: 30/09/2015 Human N-terminal Xaa-Pro-Lys N-methyltransferase 1, in complex with cofactor SAH and PmePKRIA peptide substrate Target Class: Methyltransferases Disease Areas: Cancer Site: Toronto Status: Follow-up not counted


	PDB: 5E16 Target: PP-PKG Deposited: 29/09/2015 Plasmodium falciparum cGMP-dependent protein kinase (PF14_0346), N-terminal cGMP binding domain, in complex with cyclic GMP Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up official


	PDB: 5FII Target: PAHA Deposited: 25/09/2015 Human phenylalanine hydroxylase Target Class: Amino oxidases Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5DVT Target: PP-CDPK4 Deposited: 25/09/2015 Toxoplasma gondii calcium dependent protein kinase 1, kinase domain, in complex with inhibitor SGC-1-19 Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up not counted


	PDB: 5DZC Target: PP-PKG Deposited: 25/09/2015 Plasmodium vivax protein kinase G (PVX_084705) in complex with a AMP-PNP Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up not counted


	PDB: 5DVR Target: PP-CDPK4 Deposited: 21/09/2015 Toxoplasma gondii calcium dependent protein kinase 1, kinase domain, in complex with inhibitor GW780159X Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up not counted


	PDB: 5DVU Target: PP-CDPK4 Deposited: 21/09/2015 Toxoplasma gondii calcium dependent protein kinase 1, kinase domain, in complex with inhibitor SGC-1-9 Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up not counted


	PDB: 5APA Target: ASPHA Deposited: 16/09/2015 Human aspartate beta-hydroxylase isoform a; junctin isoform 1; junctate; aspartyl/asparaginyl-beta-hydroxylase; peptide-aspartate beta-dioxygenase; humbug Target Class: Amino oxidases Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5DKC Target: SMARCA2B Deposited: 03/09/2015 Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5DKD Target: SMARCA4A Deposited: 03/09/2015 Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5DKH Target: SMARCA2B Deposited: 03/09/2015 Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5ACB Target: XX05CRK7A Deposited: 14/08/2015 Human CDK12-Cyclin K complex with inhibitor Target Class: Protein Kinase Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CZG Target: PP-BRD18 Deposited: 31/07/2015 Trypanosoma brucei hypothetical bromodomain Tb427.10.7420, in complex with bromosporine Target Class: Bromodomain Disease Areas: Chromatin and epigenetics, Parasitic disease Site: Toronto Status: Pending-Official Structure


	PDB: 5CUB Target: BAZ2BA Deposited: 24/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CUC Target: BAZ2BA Deposited: 24/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CUD Target: BAZ2BA Deposited: 24/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CUE Target: BAZ2BA Deposited: 24/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CUG Target: BAZ2BA Deposited: 24/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5A7N Target: JMJD2AA Deposited: 24/07/2015 Human jumonji domain containing 2A Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5A7O Target: JMJD2AA Deposited: 24/07/2015 Human jumonji domain containing 2A Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5A7P Target: JMJD2AA Deposited: 24/07/2015 Human jumonji domain containing 2A Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5A7Q Target: JMJD2AA Deposited: 24/07/2015 Human jumonji domain containing 2A Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5A7S Target: JMJD2AA Deposited: 24/07/2015 Human jumonji domain containing 2A Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5A7W Target: JMJD2AA Deposited: 24/07/2015 Human jumonji domain containing 2A Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5A80 Target: JMJD2AA Deposited: 24/07/2015 Human jumonji domain containing 2A Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5CU8 Target: BAZ2BA Deposited: 24/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CUA Target: BAZ2BA Deposited: 24/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CQ3 Target: BAZ2BA Deposited: 21/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CQ4 Target: BAZ2BA Deposited: 21/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CQ5 Target: BAZ2BA Deposited: 21/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CQ6 Target: BAZ2BA Deposited: 21/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CQ7 Target: BAZ2BA Deposited: 21/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CQ8 Target: BAZ2BA Deposited: 21/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CQA Target: BAZ2BA Deposited: 21/07/2015 Human bromodomain adjacent to zinc finger domain, 2B Target Class: Bromodomain Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5A9F Target: POLQA Deposited: 21/07/2015 Human DNA polymerase theta [isoform 1] Target Class: Miscellaneous Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5A9J Target: POLQA Deposited: 21/07/2015 Human DNA polymerase theta [isoform 1] Target Class: Miscellaneous Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5CLT Target: GBE1A Deposited: 16/07/2015 Human glucan (1,4-alpha-), branching enzyme 1 Target Class: Miscellaneous Disease Areas: Metabolism Site: Oxford Status: Follow-up official


	PDB: 5CLW Target: GBE1A Deposited: 16/07/2015 Human glucan (1,4-alpha-), branching enzyme 1 Target Class: Miscellaneous Disease Areas: Metabolism Site: Oxford Status: Follow-up official


	PDB: 5A6R Target: KCTD17A Deposited: 30/06/2015 Human BTB/POZ domain-containing protein KCTD17 Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Metabolism Site: Oxford Status: Official


	PDB: 5C96 Target: PTPN11 Deposited: 30/06/2015 Human protein tyrosine phosphatase, non-receptor type 11, SH2 domain, in complex with phosphotyrosine peptide Target Class: Phosphatases Disease Areas: Signalling Site: Toronto Status: Follow-up official


	PDB: 5CBD Target: PP-PKG Deposited: 30/06/2015 Plasmodium vivax protein kinase G in complex with a small molecule inhibitor Target Class: Protein Kinase Disease Areas: Parasitic disease Site: Toronto Status: Follow-up official


	PDB: 5C8G Target: PP-BRD20 Deposited: 25/06/2015 Trypanosoma brucei Tb427tmp.01.1830, bromodomain, in complex with inhibitor Target Class: Bromodomain Disease Areas: Site: Toronto Status: Pending-Official Structure


	PDB: 5C8H Target: ORC2 Deposited: 25/06/2015 Human origin recognition complex, subunit 2, C-terminal domain Target Class: Miscellaneous Disease Areas: Cancer Site: Toronto Status: Pending-Official Structure


	PDB: 5C7J Target: NEDD4 Deposited: 24/06/2015 Human neural precursor cell expressed, developmentally down-regulated 4 (E3 ubiquitin protein ligase), HECT domain, in complex with ubiquitin variant Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Cancer Site: Toronto Status: Official


	PDB: 5C7M Target: ITCH Deposited: 24/06/2015 Human itchy E3 ubiquitin protein ligase, HECT domain, in complex with a ubiquitin variant Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Cancer Site: Toronto Status: Official


	PDB: 5C6S Target: BRPF1 Deposited: 23/06/2015 Human Bromodomain and PHD Finger Containing 1, PWWP domain, in complex with fragment inhibitor Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: Pending-Official Structure


	PDB: 5C65 Target: SLC2A3A Deposited: 22/06/2015 Human solute carrier family 2 (facilitated glucose transporter), member 3 Target Class: Membrane proteins Disease Areas: Drug metabolism and toxicology Site: Oxford Status: Pending-Official Structure


	PDB: 5C5C Target: GRM7 Deposited: 19/06/2015 Human metabotropic glutamate receptor 7, extracellular ligand binding domain Target Class: Miscellaneous Disease Areas: Signalling, Neurobiology Site: Toronto Status: Pending-Official Structure


	PDB: 5C4Q Target: LdBPK_363130 Deposited: 18/06/2015 Leishmania donovani BPK282A1 (LdBPK_363130.1) bromodomain in complex with Bromosporine Target Class: Bromodomain Disease Areas: Parasitic disease Site: Toronto Status: Pending-Official Structure


	PDB: 5C0M Target: SGF29 Deposited: 12/06/2015 Human coiled-coil domain containing 101, tandem Tudor domain, in complex with peptidomimetic Target Class: Methyl-lysine readers Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 5A4R Target: MMADHCMMA Deposited: 11/06/2015 Methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria Target Class: Miscellaneous Disease Areas: Metabolism Site: Oxford Status: Pending - Official structure


	PDB: 5A3W Target: JARID1BA Deposited: 03/06/2015 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Oxidoreductases Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 4YLK Target: DYRK1AA Deposited: 02/06/2015 Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A [isoform 1] Target Class: Protein Kinase Disease Areas: Cancer, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5A3N Target: JARID1BA Deposited: 02/06/2015 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Oxidoreductases Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5A3P Target: JARID1BA Deposited: 02/06/2015 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5A3T Target: JARID1BA Deposited: 02/06/2015 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Oxidoreductases Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5BT3 Target: EP300A Deposited: 02/06/2015 Human E1A binding protein p300 Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5BT4 Target: BRD4A Deposited: 02/06/2015 Human bromodomain containing 4 [isoform long] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 5BT5 Target: BRD2A Deposited: 02/06/2015 Human bromodomain containing 2 Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 4ZQL Target: TIF1A Deposited: 15/05/2015 Human transcriptional intermediary factor 1 Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5A1H Target: SPIN3A Deposited: 01/05/2015 Human spindlin-3 Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Oxford Status: Pending - Official structure


	PDB: 5A1L Target: UTYC Deposited: 01/05/2015 Human tetratricopeptide repeat protein isoform 3; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Target Class: Oxidoreductases Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5A1F Target: JARID1BA Deposited: 29/04/2015 Human Jumonji, AT rich interactive domain 1B (RBP2-like); putative DNA/chromatin binding motif Target Class: Methyl-lysine readers Disease Areas: Site: Oxford Status: Pending - Official structure


	PDB: 5A15 Target: KCTD16A Deposited: 28/04/2015 Human BTB/POZ domain-containing protein KCTD16 Target Class: Ubiquitin Related Biology Disease Areas: Site: Oxford Status: Official


	PDB: 5A14 Target: CDK2A Deposited: 27/04/2015 Human cyclin-dependent kinase 2 [isoform 1] Target Class: Protein Kinase Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5AMF Target: BRD1A Deposited: 10/04/2015 Huma bromodomain containing protein 1 Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 5AME Target: BRD1A Deposited: 10/04/2015 Human bromodomain containing protein 1 Target Class: Bromodomain Disease Areas: Site: Oxford Status: Follow-up official


	PDB: 4Z6H Target: BRD9A Deposited: 05/04/2015 Human bromodomain containing 9 [isoform 1] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 4Z6I Target: BRD9A Deposited: 05/04/2015 Human bromodomain containing 9 [isoform 1] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 4Z3C Target: TET3 Deposited: 31/03/2015 Human tet methylcytosine dioxygenase 3, CXXC domain, in complex with DNA Target Class: Miscellaneous Disease Areas: Chromatin and epigenetics Site: Toronto Status: Pending-Official Structure


	PDB: 4UIJ Target: KCTD13A Deposited: 30/03/2015 Human BTB/POZ domain-containing protein KCTD13 Target Class: Ubiquitin Related Biology Disease Areas: Site: Oxford Status: Official


	PDB: 4Z30 Target: RC3H2 Deposited: 30/03/2015 Human ring finger and CCCH-type domains 2 (Roquin-2) Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Signalling Site: Toronto Status: Official


	PDB: 4Z31 Target: RC3H2 Deposited: 30/03/2015 Human ring finger and CCCH-type domains 2 (Roquin-2), in complex with RNA Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Signalling Site: Toronto Status: Official


	PDB: 4YZ8 Target: WHSC1L1 Deposited: 25/03/2015 Human Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1/NSD3), methyltransferase domain, in complex with the cofactor S-adenosylmethionine Target Class: Methyltransferases Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Pending-Official Structure


	PDB: 4Z02 Target: BRD1 Deposited: 25/03/2015 Human bromodomain containing 1, PWWP domain, in complex with fragment inhibitor Target Class: Methyl-lysine readers Disease Areas: Cancer, Chromatin and epigenetics Site: Toronto Status: Follow-up official


	PDB: 4YVD Target: PLRG1 Deposited: 23/03/2015 Human pleiotropic regulator 1, WD repeat Target Class: Miscellaneous Disease Areas: Signalling Site: Toronto Status: Pending-Official Structure


	PDB: 4YWQ Target: RC3H1 Deposited: 23/03/2015 Human ring finger and CCCH-type domains 1 (Roquin-1), ROQ domain Target Class: Ubiquitin Related Biology, Ubiquitylation - E3 Ligases Disease Areas: Signalling Site: Toronto Status: Follow-up not counted


	PDB: 4YY8 Target: PF13_0238 Deposited: 23/03/2015 Plasmodium falciparum kelch protein K13 (PF3D7_1343700/PF13_0238), BTB/Poz and galactose oxidase/beta-propeller domains Target Class: Miscellaneous Disease Areas: Parasitic disease Site: Toronto Status: Pending-Official Structure


	PDB: 4Z0O Target: ZCWPW2 Deposited: 23/03/2015 Human zinc finger, CW type with PWWP domain 2 (F78D mutant), Znf_CW domain Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 4Z0R Target: ZCWPW2 Deposited: 23/03/2015 Human zinc finger, CW type with PWWP domain 2 (F78R mutant), Znf_CW domain Target Class: Methyl-lysine readers Disease Areas: Chromatin and epigenetics Site: Toronto Status: Follow-up not counted


	PDB: 4YU2 Target: DYRK1AA Deposited: 18/03/2015 Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A [isoform 1] Target Class: Protein Kinase Disease Areas: Cancer, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 4YLL Target: DYRK1AA Deposited: 05/03/2015 Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A [isoform 1] Target Class: Protein Kinase Disease Areas: Cancer, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 4YLJ Target: DYRK1AA Deposited: 05/03/2015 Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A [isoform 1] Target Class: Protein Kinase Disease Areas: Cancer, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5AK7 Target: PG1424PGA Deposited: 02/03/2015 Human PG1424 peptidylarginine deiminase Target Class: Miscellaneous Disease Areas: Metabolism Site: Oxford Status: Pending-Official Structure


	PDB: 5AK8 Target: PG1424PGA Deposited: 02/03/2015 Human PG1424 peptidylarginine deiminase Target Class: Miscellaneous Disease Areas: Metabolism Site: Oxford Status: Follow-up official


	PDB: 5AJQ Target: STK10A Deposited: 26/02/2015 Human serine/threonine kinase 10 Target Class: Protein Kinase Disease Areas: Cancer Site: Oxford Status: Pending-Official Structure


	PDB: 4Y8D Target: XX03GAKA Deposited: 16/02/2015 Human crystal structure of Cyclin-G associated kinase (GAK) complexed with selective 12i inhibitor Target Class: Protein Kinase Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 5AIK Target: DYRK1AA Deposited: 15/02/2015 Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A [isoform 1] Target Class: Protein Kinase Disease Areas: Cancer, Signalling, Neurobiology Site: Oxford Status: Follow-up official


	PDB: 5AIL Target: PARP9B Deposited: 15/02/2015 Human PARP9 protein Target Class: Poly ADP-ribose polymerase Disease Areas: Chromatin and epigenetics Site: Oxford Status: Pending-Official Structure


	PDB: 5AHR Target: DCLRE1AA Deposited: 06/02/2015 Human DNA cross-link repair 1A Target Class: Miscellaneous Disease Areas: Cancer Site: Oxford Status: Follow-up official


	PDB: 4Y03 Target: PB1A Deposited: 05/02/2015 Human polybromo 1 [isoform a] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official


	PDB: 4XY8 Target: BRD9A Deposited: 02/02/2015 Human bromodomain containing 9 [isoform 1] Target Class: Bromodomain Disease Areas: Chromatin and epigenetics Site: Oxford Status: Follow-up official


	PDB: 4XY9 Target: BRD4A Deposited: 02/02/2015 Human bromodomain containing 4 [isoform long] Target Class: Bromodomain Disease Areas: Cancer, Chromatin and epigenetics, Signalling Site: Oxford Status: Follow-up official