Thursday – 14th March 2013
Opening Remarks
9:00 – 9:10 | Udo Oppermann (SGC/Botnar Research Centre, Oxford, UK) |
Plenary Presentation
9:10 – 9:50 | Brad Bernstein (Harvard University, Boston, USA): Progress and challenges in epigenomics research |
Session 1: Epigenetics, Chromatin Biology and Human Disease
Chair: Cheryl Arrowsmith (SGC, Toronto, Canada)
9:50 – 10:20 | Karin Michels (Harvard University, Boston, USA): Considerations in Study Design and Analysis of Epigenetic Mechanisms in Health and Disease |
10:20 – 10:50 | Arturas Petronis (U of Toronto, Canada): Epigenomics of Complex Neuropsychiatric Disease |
10:50 – 11:20 | Coffee Break |
11:20 – 11:50 | Giuseppe Testa (Eur. Inst. Oncology, Milan, Italy) |
11:50 – 12:20 | Hinrich Gronemeyer (IGBMC, U of Strasbourg, France) |
12:20 – 12:50 | Chris Ponting (U of Oxford, UK): Shining a light on ‘dark matter’ genes: molecular mechanisms of lncRNAs |
Lunch: 12:50 – 13:50
Session 2: Inflammation
Chair: Marc Feldmann (Kennedy Institute, Oxford, UK)
13:50 – 14:00 | Marc Feldmann (Kennedy Institute, Oxford, UK): Overview |
14:00 – 14:30 | Christopher Glass (UC San Diego, USA): A genome-wide view of macrophage activation |
14:30 – 15:00 | Gioacchino Natoli (Eur. Inst. Oncology, Milan, Italy): The macrophage epigenome and the control of inflammatory gene expression |
15:00 – 15:30 | Coffee Break |
15:30 - 16:00 | Laurens Kruidenier (GlaxoSmithKline, Stevenage, UK): Unlocking histone lysine demethylases as epigenetic drug targets |
15:50 – 16:20 | TBC |
16:20 – 16:50 | Discussion |
Friday – 15th March 2013
Session 3: Neuropsychiatry
Chair: Andre Fischer (DZNE, Göttingen, Germany)
9:00 – 9:30 | TBC |
9:30 – 10:00 | Li-Huei Tsai (MIT, USA): Epigenetic mechanisms regulating neuronal plasticity gene expression and memory formation |
10:00 – 10:30 | Coffee Break |
10:30 – 11:00 | TBC |
11:00 – 11:30 | André Fischer (DZNE, Göttingen, Germany): Defining Epigenetic Disease Signatures for treating Brain Diseases |
11:30 – 12:00 | Discussion |
Lunch: 12:00 – 13:00
Session 4: Drug Discovery
Chair: Mark Bunnage (Pfizer, Cambridge, USA)
13:00 – 13:10 | Mark Bunnage (Pfizer, Cambridge, USA): Overview |
13:10 – 13:40 | Rab Prinjha (GlaxoSmithKline, Stevenage, UK) |
13:40 – 14:10 | Daf Owen (Pfizer, Cambridge, USA): Chemical Probes for Epigenetics |
14:10 - 14:40 | Coffee Break |
14:40 – 15:10 | TBC |
15:10 – 15:40 | TBC |
15:40 – 16:10 | Discussion |
Closing Remarks
16:10 – 16:40 | Chas Bountra (SGC Oxford, UK) |