Biological probes

Potent and selective affinity reagents targeting extracellular proteins are valued reagents in both fundamental and applied biological research. Much like chemical probes they are essential for the early stages of drug discovery by allowing preclinical target validation in both academic and industrial laboratories. Biological probes could also be used for other research purposes, for example detection of a certain protein in a biological sample. 

SGC biological probes meet the following criteria:

  • In vitro affinity of at least 20 nM
  • Can immunoprecipitate its endogenous full-length protein target from a complex mixture with high selectivity
  • Significant efficacy in one or more cell-based assays


Antigen Name Antigen Region Background Information
IL-2 Full length

Interleukin 2 (IL-2) is a type of cytokine signaling molecule in the immune system that...

IRF5 E232-L434

IRF5 or Interferon-regulatory factor 5 is a transcription factor involved in the induction of...

IL-6 Full-length

Interleukin 6 (IL-6) is a cytokine with a wide variety of biological functions...

IL-8 Full-length

Interleukin 8 (IL-8) is a chemotactic factor that attracts neutrophils,...

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