An Overview of SGC Initiatives

The SGC has dedicated the past twenty years to advancing scientific knowledge by freely distributing research tools, data, and technologies. With over half of human genes and their corresponding proteins still largely unexplored, and many diseases poorly understood, SGC focuses on increasing research into these understudied areas – but can’t do it alone! Our mission involves a global call to action, encouraging collaboration across continents and sectors to address critical challenges in drug discovery and biological research. Through our cross-sector initiatives, SGC aims to catalyze breakthroughs that can transform our understanding and treatment of human diseases. 

Target 2035

An open science global movement to develop a pharmacological modulator for every protein in the human proteome by 2035.

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CACHE

A benchmarking competition to enable the best computational methods for prediction of protein-ligand binding. 

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READDI

A global organization formed to discover and develop antiviral drugs for future viral pandemics.

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Women's and Children's Health Initiative

A program focused on advancing drug discovery in reproductive biology and disease, child development, and childhood diseases.

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Conscience

A non-profit organization that uses AI and open science to advance drug discovery.

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Open Chemistry Networks

Brings together synthetic chemistry and SGC's biochemistry to create chemical probes and accelerate the search for new medicines.

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EUbOPEN

An Innovative Medicines Initiative funded project to develop high quality chemical tool compounds for 1,000 human proteins.

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Chemical Probes Portal

A free, public online resource of expert reviews and evaluations of chemical probes.

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YCharOS

An open science company to fully-characterize commercially available reagent antibodies.

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Agora Open Science Trust

A Canadian charity dedicated to creating affordable new medicines through open science.

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Treat-AD

An NIH-NIA funded open science research center to advance the next generation of drug targets for Alzheimer’s disease.

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