Bioinformatics Resources

Bioinformatics Resources

Online tools to explore structural and chemical biology

The SGC develops online tools to evaluate the disease association of human genes based on the published literature and to define the domain architecture, structural coverage and chemical coverage of human proteins. ChemBioPort is the main resource, while Chromohub and UbiHub are focused on protein families associated with chromatin and ubiqutin mediated signaling respectively.

ChemBioPort is an integrative platform to navigate the biology, structure and chemical inhibition of human proteins

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Chromohub is an online resource where users can map on phylogenetic trees disease associations, protein structures, chemical inhibitors, histone substrates, chromosomal aberrations and other types of data extracted from public repositories and the published literature.

UbiHub is a data hub for the explorers of ubiquitination pathways

Read more about our bioinformatic resources:

  1.  ChemBioPort: an online portal to navigate the structure, function and chemical inhibition of the human proteome. Liu L, Rovers E, Schapira M - Database (Oxford). 2022 Sep 27:2022:baac088 
  2. ChromoHub: a data hub for navigators of chromatin-mediated signalling. Liu L, Zhen XT, Denton E, Marsden BD, Schapira M - Bioinformatics. 2012 Aug 15;28(16):2205-6 
  3. UbiHub: a data hub for the explorers of ubiquitination pathways, Liu L, Damerell DR, Koukouflis L, Tong Y, Marsden BD, Schapira M - Bioinformatics. 2019 Aug 15;35(16):2882-2884