Cheryl Arrowsmith is a Senior Scientist at the Princess Margaret Cancer Centre, Professor in the Department of Medical Biophysics, University of Toronto, and the Chief Scientist of the Structural Genomics Consortium (SGC) at the University of Toronto. Her research focuses on the structural and chemical biology of chromatin and epigenetic regulatory factors especially as relates to cancer and drug discovery. In partnership with major pharmaceutical companies, she leads the SGC’s international open science program that is developing and distributing unencumbered Chemical Probes that support the discovery of new medicines. She received her Ph.D. from the University of Toronto and carried out postdoctoral research at Stanford University, and was co-founder of Affinium Pharmaceuticals, which developed a new medicine for multidrug resistant bacteria. She has published over 300 research articles and was recognized by Clarivate Analytics as being among the worlds top 1% of highly cited scientists in 2018, 2019 and 2022. She was elected an AAAS Fellow (2015), and a Fellow of the Royal Society of Canada (2020).
Arrowsmith CH
Nat Struct Mol Biol. 2024-3-15 . 31(3):395-396 .doi: 10.1038/s41594-024-01244-3
PMID: 38486110Schapira M, Halabelian L, Arrowsmith CH, Harding RJ
Nat Chem Biol. 2024-3-8 . .doi: 10.1038/s41589-024-01570-z
PMID: 38459278Ipas H, Gouws EB, Abell NS, Chiou PC, Devanathan SK, Hervé S, Lee S, Mercado M, Reinsborough C, Halabelian L, Arrowsmith CH, Xhemalçe B
EMBO Rep. 2024-1-23 . .doi: 10.1038/s44319-024-00059-z
PMID: 38263329Kimani SW, Perveen S, Szewezyk M, Zeng H, Dong A, Li F, Ghiabi P, Li Y, Chau I, Arrowsmith CH, Barsyte-Lovejoy D, Santhakumar V, Vedadi M, Halabelian L
Commun Biol. 2023-12-16 . 6(1):1272 .doi: 10.1038/s42003-023-05655-8
PMID: 38104184Alqazzaz MA, Luciani GM, Vu V, Machado RAC, Szewczyk MM, Adamson EC, Cheon S, Li F, Arrowsmith CH, Minden MD, Barsyte-Lovejoy D
Exp Hematol. 2023-12-10 . 104135 .doi: 10.1016/j.exphem.2023.11.009
PMID: 38072134Krishnan R, Lapierre M, Gautreau B, Nixon KCJ, El Ghamrasni S, Patel PS, Hao J, Yerlici VT, Guturi KKN, St-Germain J, Mateo F, Saad A, Algouneh A, Earnshaw R, Shili D, Seitova A, Miller J, Khosraviani N, Penn A, Ho B, Sanchez O, Hande MP, Masson JY, Brown GW, Alaoui-Jamali M, Reynolds JJ, Arrowsmith C, Raught B, Pujana MA, Mekhail K, Stewart GS, Hakem A, Hakem R
Nucleic Acids Res. 2023-9-11 . .doi: 10.1093/nar/gkad733
PMID: 37697435Bhandari V, Reichheld SE, Houliston S, Lemak A, Arrowsmith CH, Sharpe S, Houry WA
J Biol Chem. 2023-9-1 . 105199 .doi: 10.1016/j.jbc.2023.105199
PMID: 37660904Medina TS, Murison A, Smith M, Kinker GS, Chakravarthy A, Vitiello GAF, Turpin W, Shen SY, Yau HL, Sarmento OF, Faubion W, Lupien M, Silverberg MS, Arrowsmith CH, De Carvalho DD
Front Immunol. 2023-8-21 . 14:1161901 .doi: 10.3389/fimmu.2023.1161901
PMID: 37600767Wang Z, Petricca J, Liu M, Zhang S, Chen S, Li M, Besschetnova A, Patalano S, Venkataramani K, Siegfried KR, Macoska JA, Han D, Gao S, Vedadi M, Arrowsmith CH, He HH, Cai C
Proc Natl Acad Sci U S A. 2023-8-15 . 120(33):e2220472120 .doi: 10.1073/pnas.2220472120
PMID: 37549269Uguen M, Deng Y, Li F, Shell DJ, Norris-Drouin JL, Stashko MA, Ackloo S, Arrowsmith CH, James LI, Liu P, Pearce KH, Frye SV
ACS Chem Biol. 2023-8-9 . .doi: 10.1021/acschembio.3c00280
PMID: 37556795