Conformational dynamics of the TTD-PHD histone reader module of UHRF1 reveals multiple histone binding states, allosteric regulation and druggability.

Site
Pubmed id
29074623
Authors

Houliston RS, Lemak A, Iqbal A, Ivanochko D, Duan S, Kaustov L, Ong MS, Fan L, Senisterra G, Brown PJ, Wang YX, Arrowsmith CH

DOI
10.1074/jbc.M117.799700
Journal
J. Biol. Chem.
Publication Date
2017-10-26
Year
2017
N Publication Date
PI authors
Validated
Y