ZMPSTE24 missense mutations that cause progeroid diseases decrease prelamin A cleavage activity and/or protein stability.

Site
Oxford
Pubmed id
29794150
Authors

Spear ED, Hsu ET, Nie L, Carpenter EP, Hrycyna CA, Michaelis S

DOI
10.1242/dmm.033670
Journal
Dis Model Mech
Publication Date
2018-5-24
Year
2018
N Publication Date
Validated
Y