Novel Quinazolinone Inhibitors of ALK2 Flip between Alternate Binding Modes: Structure-Activity Relationship, Structural Characterization, Kinase Profiling, and Cellular Proof of Concept.

Site
Oxford
Pubmed id
30085668
Authors

Hudson L, Mui J, Vázquez S, Carvalho DM, Williams E, Jones C, Bullock AN, Hoelder S

DOI
10.1021/acs.jmedchem.8b00782
Journal
J. Med. Chem.
Publication Date
2018-8-7
Year
2018
N Publication Date
Validated
Y