DFG-1 residue controls inhibitor binding mode and affinity providing a basis for rational design of kinase inhibitor selectivity.

Site
Oxford
Frankfurt
Pubmed id
32787076
Authors

Schröder M, Bullock AN, Fedorov O, Bracher F, Chaikuad A, Knapp S

DOI
10.1021/acs.jmedchem.0c00898
Journal
J. Med. Chem.
Publication Date
2020-8-12
Year
2020
N Publication Date
PI authors
Knapp
Validated
Y