PKC isoforms activate LRRK1 kinase by phosphorylating conserved residues (Ser1064, Ser1074 and Thr1075) within the CORB GTPase domain.

Site
Frankfurt
Pubmed id
36040231
Authors

Malik AU, Karapetsas A, Nirujogi RS, Chatterjee D, Phung TK, Wightman M, Gourlay R, Morrice NA, Mathea S, Knapp S, Alessi DR

DOI
10.1042/BCJ20220308
Journal
Biochem J
Publication Date
2022-8-30
Year
2022
N Publication Date
PI authors
Knapp
Validated
Y