Activation of endogenous PRKN by structural derepression is linked to increased turnover of the E3 ubiquitin ligase.

Fiesel F, Bustillos B, Watzlawik J, Chen C, Berryer M, Zhang J, Boneski P, Hayes C, Bredenberg J, Deneault E, You Z, Abdien N, Aprahamian N, Goldsmith T, Baninameh Z, Cocker L, Zhang H, Goldberg M, Fon E, Trempe JF, Virdee S, Durcan T, Springer W