Development of pyrazolo[1,5-a]pyrimidine based macrocyclic kinase inhibitors targeting AAK1.

Mensing TE, Kurz CG, Amrhein JA, Ehret TAL, Preuss F, Mathea S, Karim M, Tran DHN, Kadlecova Z, Tolvanen TA, Martinez-Molina D, Müller S, Einav S, Knapp S, Hanke T