Selective Brain-Penetrant TTBK1 Inhibitors Modulate TDP-43 Pathology and Rescue Cognitive Deficits in a Mouse Model of TDP-43 Proteinopathy.

Sanchez-Santos C, Jimenez-Amor A, Martinez-Gonzalez L, Nozal V, Martin-Morales R, Aledavood E, Bausela D, Merrigan K, Diaz-Palacios K, Zhubi R, Knapp S, Garcia-Gonzalo FR, Rodriguez-Cueto C, Gil C, de Lago E, Martinez A