Opher Gileadi obtained his PhD in Biochemistry at the Hebrew University and was then a postdoctoral fellow at Stanford University Medical School. Subsequently he led a research group at the Weizmann Institute of Science. From 2004-2021 he was both at SGC University of Oxford, first as head of the Biotechnology group, then as Principal Investigator of the Genome Integrity & Repair Group as well as Head of the SGC Kinase Chemical Biology Center at the State University of Campinas (UNICAMP). In 2021 Opher took at position as Executive Director, Protein Science and Structure at Exscientia, but re-join the SGC at Karolinska in 2023.
Opher leads the Protein Science team at SGC Karolinska, focussing on developing antibodies and target-enabling packages (TEPs) for under-investigated proteins of humans and pathogens.
Pike AC, Gomathinayagam S, Swuec P, Berti M, Zhang Y, Schnecke C, Marino F, von Delft F, Renault L, Costa A, Gileadi O, Vindigni A
Proc. Natl. Acad. Sci. U.S.A.. 2015-3-23 . .doi: 10.1073/pnas.1417594112
PMID: 25831490Edwards AM, Arrowsmith CH, Bountra C, Bunnage ME, Feldmann M, Knight JC, Patel DD, Prinos P, Taylor MD, Sundström M, Barker P, Barsyte D, Bengtson MH, Bell C, Bowness P, Boycott KM, Buser-Doepner C, Carpenter CL, Carr AJ, Clark K, Das AM, Dhanak D, Dirks P, Ellis J, Fantin VR, Flores C, Fon EA, Frail DE, Gileadi O, O'Hagan RC, Howe T, Isaac JT, Jabado N, Jakobsson PJ, Klareskog L, Knapp S, Lee WH, Lima-Fernandes E, Lundberg IE, Marshall J, Massirer KB, MacKenzie AE, Maruyama T, Mueller-Fahrnow A, Muthuswamy S, Nanchahal J, O'Brien C, Oppermann U, Ostermann N, Petrecca K, Pollock BG, Poupon V, Prinjha RK, Rosenberg SH, Rouleau G, Skingle M, Slutsky AS, Smith GA, Verhelle D, Widmer H, Young LT
Nat Rev Drug Discov. 2015-2-20 . 14(3):149-50 .doi: 10.1038/nrd4565
PMID: 25722227Newman JA, Cooper CD, Aitkenhead H, Gileadi O
J. Biol. Chem.. 2015-2-10 . .doi: 10.1074/jbc.M114.619270
PMID: 25670864Iyama T, Lee SY, Berquist BR, Gileadi O, Bohr VA, Seidman MM, McHugh PJ, Wilson DM
Nucleic Acids Res.. 2014-12-10 . .doi: 10.1093/nar/gku1279
PMID: 25505141Chatterjee S, Zagelbaum J, Savitsky P, Sturzenegger A, Huttner D, Janscak P, Hickson ID, Gileadi O, Rothenberg E
Nat Commun. 2014-11-25 . 5:5556 .doi: 10.1038/ncomms6556
PMID: 25418155Walport LJ, Hopkinson RJ, Vollmar M, Madden SK, Gileadi C, Oppermann U, Schofield CJ, Johansson C
J. Biol. Chem.. 2014-5-5 . .doi: 10.1074/jbc.M114.555052
PMID: 24798337Johansson C, Tumber A, Che K, Cain P, Nowak R, Gileadi C, Oppermann U
Epigenomics. 2014-3-4 . 6(1):89-120 .doi: 10.2217/epi.13.79
PMID: 24579949Cooper CD, Newman JA, Gileadi O
Biochem. Soc. Trans.. 2014-2-1 . 42(1):130-8 .doi: 10.1042/BST20130227
PMID: 24450640Gileadi O
Biochem. Soc. Trans.. 2014-2-1 . 42(1):108-13 .doi: 10.1042/BST20130228
PMID: 24450636Mahajan P, Strain-Damerell C, Gileadi O, Burgess-Brown NA
Methods Mol. Biol.. 2013-11-10 . 1091:95-121 .doi: 10.1007/978-1-62703-691-7_6
PMID: 24203326