Michael Sundström

Michael Sundström

SGC Karolinska

Sundström

Michael Sundström

+46 70 65 44 662
SGC, Department of Medicine, Karolinska University Hospital and Karolinska Institutet, Tomtebodav. 23A, 171 65 Solna, Sweden

Affiliations

Biography

Michael Sundstrom received his PhD from Uppsala, followed by Postdoctoral studies at Karolinska Institute. From 1993-2000 he was at Pharmacia as Director for structure-based drug design and oncology R&D portfolio management. Between 2001 and 2003 he held senior positions at the Swedish Biotechs Actar and Biovitrum. In 2003 he joined the Structural Genomics Consortium (SGC) at the University of Oxford, as Chief Scientist. In 2007 he assumed the position as Managing Director for the Novo Nordisk Foundation Center for Protein Research (Copenhagen). In 2011, he was Vice President of Discovery Research at Karolinska Development. He then re-joined the SGC inmid-2014, as Scientific Director of European Initiatives at SGC.

Michael has three main responsibilities within the SGC; i) member of the global research leadership team coordinating projects and activities of common interest within the consortium; ii) site head for SGC Karolinska and iii) main scientific focus and responsibility for the SGC Tissue Platforms in Stockholm, Frankfurt, Toronto and Montreal; working to establish high quality cell-based assays using patient-derived cell systems in inflammation, oncology and neurodegenerative diseases.

Michael currently leads (ad interim) the efforts in the Tissue Assay platform at SGC Karolinska.
 

2007

The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins.

Gileadi O, Knapp S, Lee WH, Marsden BD, Müller S, Niesen FH, Kavanagh KL, Ball LJ, von Delft F, Doyle DA, Oppermann UC, Sundström M

J. Struct. Funct. Genomics. 2007-10-12 . 8(2-3):107-19 .doi: 10.1007/s10969-007-9027-2

PMID: 17932789

Insights for the development of specific kinase inhibitors by targeted structural genomics.

Fedorov O, Sundström M, Marsden B, Knapp S

Drug Discov. Today. 2007-3-29 . 12(9-10):365-72 .doi: 10.1016/j.drudis.2007.03.006

PMID: 17467572

2006

Inhibition of protein-protein interactions: the discovery of druglike beta-catenin inhibitors by combining virtual and biophysical screening.

Trosset JY, Dalvit C, Knapp S, Fasolini M, Veronesi M, Mantegani S, Gianellini LM, Catana C, Sundström M, Stouten PF, Moll JK

Proteins. 2006-7-1 . 64(1):60-7 .doi: 10.1002/prot.20955

PMID: 16568448

Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase.

Bullock AN, Debreczeni JE, Edwards AM, Sundström M, Knapp S

Proc. Natl. Acad. Sci. U.S.A.. 2006-5-16 . 103(20):7637-42 .doi: 10.1073/pnas.0601638103

PMID: 16675548