Welcome to the Structural Genomics Consortium

The SGC is a global private public partnership focused on understanding the functions of all human proteins. Over the past two decades, we have determined thousands of protein structures, and developed new chemical probes. We are now scaling up these efforts along with the computational community, using artificial intelligence to transform early drug discovery. Explore our work and see how we are accelerating drug discovery through open-access research.

19.06.2024

Dr. Rachel Harding is the recipient of the 2024 Nancy S. Wexler Young Investigator Prize

by: SGC

The Structural Genomics Consortium at the University of Toronto is thrilled to announce that Assistant Professor and Principal Investigator, Dr. Rachel Harding, has been honored with the Hereditary Disease Foundation’s (HDF) 2024 Nancy S. Wexler Young Investigator Prize. This award is given annually to an early-career researcher who demonstrates exceptional quality, innovation, and commitment in the field of hereditary disease research.

Mario Henrique Bengtson

bengtson@unicamp.br
Google Scholar

Affiliations

Principal Investigator at CQMED Professor in Instituto de Biologia, UNICAMP Department of Biochemistry and Tissue Biology

Biography

Dr. Bengtson holds a PhD in Biochemistry and Molecular Biology from São Paulo University (USP), awarded in 2002. He completed two postdoctoral fellowships: the first at the Genomics Institute of the Novartis Research Foundation (GNF) from 2003 to 2006, and the second at The Scripps Research Institute from 2007 to 2012. Since 2013, he has been an assistant professor at UNICAMP.

Research Areas

Dr. Bengtson’s lab is dedicated to studying translational ubiquitination and degradation of proteins, as well as the translational regulation of gene expression. The lab also investigates how failures in these mechanisms are implicated in human diseases.

SGC-Unicamp

The SGC at the Center of Medicinal Chemistry of UNICAMP (CQMED) is an affiliated SGC site. It is composed of a team of scientists who are dedicated on characterizing new potential disease targets and developing chemical probes for these targets. This site is located at the Universidade Estadual de Campinas in Brazil and focuses on characterizing Target enabling packages (TEPs) for understudied protein targets. These targets include areas such as female fertility, ribosomal quality control, RNA binding proteins and kinases in human and in infectious diseases.

Team’s capacities:

Protein: KCNK10
PDB ID: 8QZ4
Deposition Date: Thursday 26th October 2023
Authors: Rodstrom, K.E.J., Pike, A.C.W., Baronina, A., Ang, J., Bushell, S.R., Chalk, R., Mukhopadhyay, S.M.M., Pardon, E., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N.A., Tucker, S.J., Steyaert, J., Carpenter, E.P.
Protein: KCNK10
PDB ID: 8QZ3
Deposition Date: Thursday 26th October 2023
Authors: Baronina, A., Pike, A.C.W., Rodstrom, K.E.J., Ang, J., Bushell, S.R., Chalk, R., Mukhopadhyay, S.M.M., Pardon, E., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N.A., Tucker, S.J., Steyaert, J., Carpenter, E.P.
Protein: KCNK10
PDB ID: 8QZ2
Deposition Date: Thursday 26th October 2023
Authors: Baronina, A., Pike, A.C.W., Rodstrom, K.E.J., Ang, J., Bushell, S.R., Chalk, R., Mukhopadhyay, S.M.M., Pardon, E., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N.A., Tucker, S.J., Steyaert, J., Carpenter, E.P.
Protein: KCNK10
PDB ID: 8QZ1
Deposition Date: Thursday 26th October 2023
Authors: Rodstrom, K.E.J., Pike, A.C.W., Baronina, A., Ang, J., Bushell, S.R., Chalk, R., Mukhopadhyay, S.M.M., Pardon, E., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N.A., Tucker, S.J., Steyaert, J., Carpenter, E.P.
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