A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics. Read more about A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics.
Structure and functional characterization of the atypical human kinase haspin. Read more about Structure and functional characterization of the atypical human kinase haspin.
Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi. Read more about Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi.
SH2 domains: modulators of nonreceptor tyrosine kinase activity. Read more about SH2 domains: modulators of nonreceptor tyrosine kinase activity.
Screening for inhibitors of low-affinity epigenetic peptide-protein interactions: an AlphaScreen-based assay for antagonists of methyl-lysine binding proteins. Read more about Screening for inhibitors of low-affinity epigenetic peptide-protein interactions: an AlphaScreen-based assay for antagonists of methyl-lysine binding proteins.
Evaluation of substituted N,N'-diarylsulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase. Read more about Evaluation of substituted N,N'-diarylsulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase.
PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA. Read more about PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA.
Crystal structure of the PHF8 Jumonji domain, an Nepsilon-methyl lysine demethylase. Read more about Crystal structure of the PHF8 Jumonji domain, an Nepsilon-methyl lysine demethylase.
Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78. Read more about Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78.
The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma. Read more about The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma.
