Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches. Read more about Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches.
Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888. Read more about Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888.
A miniaturized screen for inhibitors of Jumonji histone demethylases. Read more about A miniaturized screen for inhibitors of Jumonji histone demethylases.
Toward a unified nomenclature for mammalian ADP-ribosyltransferases. Read more about Toward a unified nomenclature for mammalian ADP-ribosyltransferases.
Pharmacophore screening of the protein data bank for specific binding site chemistry. Read more about Pharmacophore screening of the protein data bank for specific binding site chemistry.
A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation. Read more about A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation.
PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers. Read more about PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers.
Structural basis of human CYP51 inhibition by antifungal azoles. Read more about Structural basis of human CYP51 inhibition by antifungal azoles.
Assessing the stability of membrane proteins to detect ligand binding using differential static light scattering. Read more about Assessing the stability of membrane proteins to detect ligand binding using differential static light scattering.
