Structural genomics-impact on biomedicine and drug discovery. Read more about Structural genomics-impact on biomedicine and drug discovery.
Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity. Read more about Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity.
Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design. Read more about Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design.
A software tool to accelerate design of protein constructs for recombinant expression. Read more about A software tool to accelerate design of protein constructs for recombinant expression.
N-myristoyltransferase inhibitors as new leads to treat sleeping sickness. Read more about N-myristoyltransferase inhibitors as new leads to treat sleeping sickness.
Crystal structure of the human ubiquitin-activating enzyme 5 (UBA5) bound to ATP: mechanistic insights into a minimalistic E1 enzyme. Read more about Crystal structure of the human ubiquitin-activating enzyme 5 (UBA5) bound to ATP: mechanistic insights into a minimalistic E1 enzyme.
Tamoxifen enhances the Hsp90 molecular chaperone ATPase activity. Read more about Tamoxifen enhances the Hsp90 molecular chaperone ATPase activity.
Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function. Read more about Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function.
Probing the structural basis of RecQ helicase function. Read more about Probing the structural basis of RecQ helicase function.
New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights. Read more about New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights.
