Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors. Read more about Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors.
Crystal structure of a prokaryotic homologue of the mammalian oligopeptide-proton symporters, PepT1 and PepT2. Read more about Crystal structure of a prokaryotic homologue of the mammalian oligopeptide-proton symporters, PepT1 and PepT2.
Newly discovered and characterized antivirulence compounds inhibit bacterial mono-ADP-ribosyltransferase toxins. Read more about Newly discovered and characterized antivirulence compounds inhibit bacterial mono-ADP-ribosyltransferase toxins.
Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence. Read more about Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence.
Structural and mechanistic studies on γ-butyrobetaine hydroxylase. Read more about Structural and mechanistic studies on γ-butyrobetaine hydroxylase.
Challenges and prospects for pharmacotherapy in functional gastrointestinal disorders. Read more about Challenges and prospects for pharmacotherapy in functional gastrointestinal disorders.
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation. Read more about Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation.
Animal models of epigenetic regulation in neuropsychiatric disorders. Read more about Animal models of epigenetic regulation in neuropsychiatric disorders.
Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases. Read more about Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases.
