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Thermal denaturation assays in chemical biology.

  • Read more about Thermal denaturation assays in chemical biology.

Protein aggregates are recruited to aggresome by histone deacetylase 6 via unanchored ubiquitin C termini.

  • Read more about Protein aggregates are recruited to aggresome by histone deacetylase 6 via unanchored ubiquitin C termini.

Structural and kinetic evidence that catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates.

  • Read more about Structural and kinetic evidence that catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates.

7,8-dichloro-1-oxo-β-carbolines as a versatile scaffold for the development of potent and selective kinase inhibitors with unusual binding modes.

  • Read more about 7,8-dichloro-1-oxo-β-carbolines as a versatile scaffold for the development of potent and selective kinase inhibitors with unusual binding modes.

Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family.

  • Read more about Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family.

Druggability of methyl-lysine binding sites.

  • Read more about Druggability of methyl-lysine binding sites.

Structural and functional insights into the DNA replication factor Cdc45 reveal an evolutionary relationship to the DHH family of phosphoesterases.

  • Read more about Structural and functional insights into the DNA replication factor Cdc45 reveal an evolutionary relationship to the DHH family of phosphoesterases.

Conformational plasticity of glycogenin and its maltosaccharide substrate during glycogen biogenesis.

  • Read more about Conformational plasticity of glycogenin and its maltosaccharide substrate during glycogen biogenesis.

Structural insights into the allosteric effects of 4EBP1 on the eukaryotic translation initiation factor eIF4E.

  • Read more about Structural insights into the allosteric effects of 4EBP1 on the eukaryotic translation initiation factor eIF4E.

Recombinant protein quality evaluation: proposal for a minimal information standard.

  • Read more about Recombinant protein quality evaluation: proposal for a minimal information standard.

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