Fluorescence-based methods for screening writers and readers of histone methyl marks. Read more about Fluorescence-based methods for screening writers and readers of histone methyl marks.
Analysis of conditions affecting auto-phosphorylation of human kinases during expression in bacteria. Read more about Analysis of conditions affecting auto-phosphorylation of human kinases during expression in bacteria.
Target highlights in CASP9: Experimental target structures for the critical assessment of techniques for protein structure prediction. Read more about Target highlights in CASP9: Experimental target structures for the critical assessment of techniques for protein structure prediction.
Structural basis for specific binding of human MPP8 chromodomain to histone H3 methylated at lysine 9. Read more about Structural basis for specific binding of human MPP8 chromodomain to histone H3 methylated at lysine 9.
Expressing the human proteome for affinity proteomics: optimising expression of soluble protein domains and in vivo biotinylation. Read more about Expressing the human proteome for affinity proteomics: optimising expression of soluble protein domains and in vivo biotinylation.
Cofactor mobility determines reaction outcome in the IMPDH and GMPR (β-α)8 barrel enzymes. Read more about Cofactor mobility determines reaction outcome in the IMPDH and GMPR (β-α)8 barrel enzymes.
Thermal denaturation assays in chemical biology. Read more about Thermal denaturation assays in chemical biology.
Protein aggregates are recruited to aggresome by histone deacetylase 6 via unanchored ubiquitin C termini. Read more about Protein aggregates are recruited to aggresome by histone deacetylase 6 via unanchored ubiquitin C termini.
Structural and kinetic evidence that catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates. Read more about Structural and kinetic evidence that catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates.
7,8-dichloro-1-oxo-β-carbolines as a versatile scaffold for the development of potent and selective kinase inhibitors with unusual binding modes. Read more about 7,8-dichloro-1-oxo-β-carbolines as a versatile scaffold for the development of potent and selective kinase inhibitors with unusual binding modes.
