Small-molecule inhibitors of the c-Fes protein-tyrosine kinase. Read more about Small-molecule inhibitors of the c-Fes protein-tyrosine kinase.
Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism. Read more about Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Novel insights into the regulation of malarial calcium-dependent protein kinase 1. Read more about Novel insights into the regulation of malarial calcium-dependent protein kinase 1.
The PHD and chromo domains regulate the ATPase activity of the human chromatin remodeler CHD4. Read more about The PHD and chromo domains regulate the ATPase activity of the human chromatin remodeler CHD4.
The structure of the full-length tetrameric PKA regulatory RIIβ complex reveals the mechanism of allosteric PKA activation. Read more about The structure of the full-length tetrameric PKA regulatory RIIβ complex reveals the mechanism of allosteric PKA activation.
Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation. Read more about Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation.
The Role of Protein Structural Analysis in the Next Generation Sequencing Era. Read more about The Role of Protein Structural Analysis in the Next Generation Sequencing Era.
Structural basis for substrate specificity and catalysis of human histone acetyltransferase 1. Read more about Structural basis for substrate specificity and catalysis of human histone acetyltransferase 1.
Rapid determination of multiple linear kinase substrate motifs by mass spectrometry. Read more about Rapid determination of multiple linear kinase substrate motifs by mass spectrometry.
Structure of MMACHC reveals an arginine-rich pocket and a domain-swapped dimer for its B12 processing function. Read more about Structure of MMACHC reveals an arginine-rich pocket and a domain-swapped dimer for its B12 processing function.
