IQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain fold. Read more about IQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain fold.
A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Read more about A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Epigenetic protein families: a new frontier for drug discovery. Read more about Epigenetic protein families: a new frontier for drug discovery.
Structural basis of the chromodomain of Cbx3 bound to methylated peptides from histone h1 and G9a. Read more about Structural basis of the chromodomain of Cbx3 bound to methylated peptides from histone h1 and G9a.
Small-molecule inhibitors of the c-Fes protein-tyrosine kinase. Read more about Small-molecule inhibitors of the c-Fes protein-tyrosine kinase.
Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism. Read more about Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Novel insights into the regulation of malarial calcium-dependent protein kinase 1. Read more about Novel insights into the regulation of malarial calcium-dependent protein kinase 1.
The PHD and chromo domains regulate the ATPase activity of the human chromatin remodeler CHD4. Read more about The PHD and chromo domains regulate the ATPase activity of the human chromatin remodeler CHD4.
The structure of the full-length tetrameric PKA regulatory RIIβ complex reveals the mechanism of allosteric PKA activation. Read more about The structure of the full-length tetrameric PKA regulatory RIIβ complex reveals the mechanism of allosteric PKA activation.
Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation. Read more about Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation.
