Inhibition of protein-protein interactions: the discovery of druglike beta-catenin inhibitors by combining virtual and biophysical screening. Read more about Inhibition of protein-protein interactions: the discovery of druglike beta-catenin inhibitors by combining virtual and biophysical screening.
The crystal structure of human receptor protein tyrosine phosphatase kappa phosphatase domain 1. Read more about The crystal structure of human receptor protein tyrosine phosphatase kappa phosphatase domain 1.
Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase. Read more about Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase.
The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs. Read more about The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs.
The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding. Read more about The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding.
Crystal structures of human sulfotransferases SULT1B1 and SULT1C1 complexed with the cofactor product adenosine-3'- 5'-diphosphate (PAP). Read more about Crystal structures of human sulfotransferases SULT1B1 and SULT1C1 complexed with the cofactor product adenosine-3'- 5'-diphosphate (PAP).
MAPK-specific tyrosine phosphatases: new targets for drug discovery? Read more about MAPK-specific tyrosine phosphatases: new targets for drug discovery?
Structural basis for molecular recognition and presentation of histone H3 by WDR5. Read more about Structural basis for molecular recognition and presentation of histone H3 by WDR5.
Structure of human protein kinase C eta (PKCeta) C2 domain and identification of phosphorylation sites. Read more about Structure of human protein kinase C eta (PKCeta) C2 domain and identification of phosphorylation sites.
Carbonyl reductases: the complex relationships of mammalian carbonyl- and quinone-reducing enzymes and their role in physiology. Read more about Carbonyl reductases: the complex relationships of mammalian carbonyl- and quinone-reducing enzymes and their role in physiology.
