Protein-protein interaction site mapping using NMR-detected mutational scanning. Read more about Protein-protein interaction site mapping using NMR-detected mutational scanning.
Insights for the development of specific kinase inhibitors by targeted structural genomics. Read more about Insights for the development of specific kinase inhibitors by targeted structural genomics.
Structure and mechanism of spermidine synthases. Read more about Structure and mechanism of spermidine synthases.
Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity. Read more about Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.
Crystallization and preliminary X-ray analysis of phage Mu activator protein C in a complex with promoter DNA. Read more about Crystallization and preliminary X-ray analysis of phage Mu activator protein C in a complex with promoter DNA.
Activation segment exchange: a common mechanism of kinase autophosphorylation? Read more about Activation segment exchange: a common mechanism of kinase autophosphorylation?
Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder. Read more about Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder.
Structural analysis identifies imidazo[1,2-b]pyridazines as PIM kinase inhibitors with in vitro antileukemic activity. Read more about Structural analysis identifies imidazo[1,2-b]pyridazines as PIM kinase inhibitors with in vitro antileukemic activity.
Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases. Read more about Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases.
Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO. Read more about Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO.
