Type 1 11beta-hydroxysteroid dehydrogenase as universal drug target in metabolic diseases? Read more about Type 1 11beta-hydroxysteroid dehydrogenase as universal drug target in metabolic diseases?
Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8). Read more about Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8).
Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination. Read more about Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination.
Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity. Read more about Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity.
Screening for ligands using a generic and high-throughput light-scattering-based assay. Read more about Screening for ligands using a generic and high-throughput light-scattering-based assay.
Reversible sequestration of active site cysteines in a 2Fe-2S-bridged dimer provides a mechanism for glutaredoxin 2 regulation in human mitochondria. Read more about Reversible sequestration of active site cysteines in a 2Fe-2S-bridged dimer provides a mechanism for glutaredoxin 2 regulation in human mitochondria.
Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Read more about Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Crystal structure of human inosine triphosphatase. Substrate binding and implication of the inosine triphosphatase deficiency mutation P32T. Read more about Crystal structure of human inosine triphosphatase. Substrate binding and implication of the inosine triphosphatase deficiency mutation P32T.
The crystal structures of human calpains 1 and 9 imply diverse mechanisms of action and auto-inhibition. Read more about The crystal structures of human calpains 1 and 9 imply diverse mechanisms of action and auto-inhibition.
Resonance assignment of the RGS domain of human RGS10. Read more about Resonance assignment of the RGS domain of human RGS10.
